ES2170117T3 - Procedimiento para acoplar anticuerpos a un nuevo sustrato de latex y su uso en inmunoensayos. - Google Patents
Procedimiento para acoplar anticuerpos a un nuevo sustrato de latex y su uso en inmunoensayos.Info
- Publication number
- ES2170117T3 ES2170117T3 ES95116241T ES95116241T ES2170117T3 ES 2170117 T3 ES2170117 T3 ES 2170117T3 ES 95116241 T ES95116241 T ES 95116241T ES 95116241 T ES95116241 T ES 95116241T ES 2170117 T3 ES2170117 T3 ES 2170117T3
- Authority
- ES
- Spain
- Prior art keywords
- latex
- procedure
- new substrate
- antibodies
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000004816 latex Substances 0.000 title abstract 3
- 239000000758 substrate Substances 0.000 title abstract 2
- 230000008878 coupling Effects 0.000 title 1
- 238000010168 coupling process Methods 0.000 title 1
- 238000005859 coupling reaction Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Nanotechnology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
SE PREPARAN NUEVOS REACTIVOS ANTICUERPO-LATEX QUE UTILIZAN UN NUEVO ENLACE COVALENTE ESPECIFICO DEL LUGAR DE ANTICUERPOS, A TRAVES DE SUS UNIDADES DE FC INTERFERENTES, SOBRE NUEVOS SUSTRATOS ESFERICOS DE LATEX POLIMERICO, CONSERVANDO ASI LOS LUGARES DE ENLACE A LOS ANTIGENOS DE LOS ANTICUERPOS. ESTA INMOVILIZACION DE LOS ANTICUERPOS ES ESENCIAL PARA ENSAYOS DE ALTA ACTIVIDAD ESPECIFICA Y SENSIBILIDAD, Y TAMBIEN ES ECONOMICA Y MUCHO MAS SENCILLA QUE OTRAS INMOVILIZACIONES COVALENTES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/330,259 US5585278A (en) | 1994-10-27 | 1994-10-27 | Method for coupling antibody to novel latex substrate and its use in immunoassay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2170117T3 true ES2170117T3 (es) | 2002-08-01 |
Family
ID=23288981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95116241T Expired - Lifetime ES2170117T3 (es) | 1994-10-27 | 1995-10-16 | Procedimiento para acoplar anticuerpos a un nuevo sustrato de latex y su uso en inmunoensayos. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5585278A (es) |
| EP (1) | EP0709676B2 (es) |
| JP (1) | JPH08211060A (es) |
| CA (1) | CA2156588A1 (es) |
| DE (1) | DE69524842T2 (es) |
| ES (1) | ES2170117T3 (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6379975B1 (en) * | 1996-11-27 | 2002-04-30 | T.A.C. Thrombosis And Coagulation Aktiebolag | Methods and reagents for determining protein S |
| FI101543B1 (fi) * | 1996-12-17 | 1998-07-15 | Orion Yhtymae Oy | Biomolekyylien kytkeminen kiintofaasiin |
| US6267722B1 (en) | 1998-02-03 | 2001-07-31 | Adeza Biomedical Corporation | Point of care diagnostic systems |
| US6394952B1 (en) | 1998-02-03 | 2002-05-28 | Adeza Biomedical Corporation | Point of care diagnostic systems |
| WO2001077182A1 (en) * | 2000-04-07 | 2001-10-18 | Matsushita Electric Industrial Co., Ltd. | Antibody/carrier complex, process for producing the same, method of controlling antigen-antibody reaction by using the same and immunoassay method |
| US7935539B2 (en) * | 2003-02-14 | 2011-05-03 | Siemens Healthcare Diagnostics, Inc. | Generic method for latex agglutination assays |
| AU2004258113B2 (en) * | 2003-07-07 | 2009-11-05 | University Of North Carolina At Chapel Hill | Method and system for detection of von Willebrand factor (vWF) multimers |
| US7771660B2 (en) * | 2004-05-04 | 2010-08-10 | University Of North Carolina At Chapel Hill | Electrophoretic interactive spectral methods and devices for the detection and/or characterization of biological particles |
| US20060154372A1 (en) * | 2004-12-21 | 2006-07-13 | Arter Thomas C | Providing additional motion in assays |
| WO2011035385A1 (en) * | 2009-09-24 | 2011-03-31 | Monash University | Testing device for identifying antigens and antibodies in biofluids |
| ES2628351T3 (es) * | 2010-10-13 | 2017-08-02 | Pharma Diagnostics Nv | Método para recubrir nanopartículas |
| JP2012242278A (ja) * | 2011-05-20 | 2012-12-10 | Rohm Co Ltd | マイクロチップに用いられる検査試薬 |
| US9274107B2 (en) | 2011-05-20 | 2016-03-01 | Rohm Co., Ltd. | Microchip, measurement system and method using the same, and test reagent to be used for microchip |
| JP6190132B2 (ja) * | 2013-03-21 | 2017-08-30 | 学校法人近畿大学 | 遺伝子試料導入用基板及び遺伝子試料導入方法 |
| JP6900207B2 (ja) * | 2017-03-09 | 2021-07-07 | Jsr株式会社 | プローブ結合担体の製造方法、および、標的物質を検出または分離する方法 |
| JP2022155547A (ja) * | 2021-03-30 | 2022-10-13 | ミナリスメディカル株式会社 | 蛋白質が結合したラテックス粒子の安定化方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4210723A (en) * | 1976-07-23 | 1980-07-01 | The Dow Chemical Company | Method of coupling a protein to an epoxylated latex |
| US4164558A (en) * | 1976-11-22 | 1979-08-14 | Massachusetts Institute Of Technology | Method for optimizing reagents for agglutination reactions |
| US4184849A (en) * | 1977-12-05 | 1980-01-22 | Technicon Instruments Corporation | Mixed agglutination |
| GB2013211B (en) * | 1978-01-26 | 1982-06-30 | Technicon Instr | Immunoassays using f(ab')2 fragments |
| US4401765A (en) * | 1981-09-01 | 1983-08-30 | E. I. Du Pont De Nemours And Company | Covalently bonded high refractive index particle reagents and their use in light scattering immunoassays |
| US4480042A (en) * | 1981-10-28 | 1984-10-30 | E. I. Du Pont De Nemours And Company | Covalently bonded high refractive index particle reagents and their use in light scattering immunoassays |
| JPS59224565A (ja) * | 1983-04-28 | 1984-12-17 | Morinaga Milk Ind Co Ltd | 抗原検出用試薬 |
| DE3622993A1 (de) † | 1986-07-09 | 1988-01-21 | Behringwerke Ag | Dispersionspolymere, biologisch aktive dispersionspolymere, verfahren zu ihrer herstellung und verwendung als diagnostisches mittel |
| DE3919873A1 (de) * | 1989-06-19 | 1990-12-20 | Behringwerke Ag | Magnetische protein-konjugate, verfahren zu ihrer herstellung und ihre verwendung |
| FR2676451B1 (fr) * | 1991-05-15 | 1993-08-06 | Bio Merieux | Procede pour preparer un latex a groupements fonctionnels de surface et latex obtenu. |
-
1994
- 1994-10-27 US US08/330,259 patent/US5585278A/en not_active Expired - Fee Related
-
1995
- 1995-08-21 CA CA002156588A patent/CA2156588A1/en not_active Abandoned
- 1995-10-16 EP EP95116241A patent/EP0709676B2/en not_active Expired - Lifetime
- 1995-10-16 ES ES95116241T patent/ES2170117T3/es not_active Expired - Lifetime
- 1995-10-16 DE DE69524842T patent/DE69524842T2/de not_active Expired - Fee Related
- 1995-10-27 JP JP7302267A patent/JPH08211060A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPH08211060A (ja) | 1996-08-20 |
| EP0709676A3 (en) | 1996-11-20 |
| EP0709676B1 (en) | 2002-01-02 |
| DE69524842D1 (de) | 2002-02-07 |
| US5585278A (en) | 1996-12-17 |
| EP0709676B2 (en) | 2007-03-21 |
| CA2156588A1 (en) | 1996-04-28 |
| EP0709676A2 (en) | 1996-05-01 |
| DE69524842T2 (de) | 2002-09-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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