ES2171398T3 - Acidos nucleicos viricos vegetales recombinantes. - Google Patents
Acidos nucleicos viricos vegetales recombinantes.Info
- Publication number
- ES2171398T3 ES2171398T3 ES92916441T ES92916441T ES2171398T3 ES 2171398 T3 ES2171398 T3 ES 2171398T3 ES 92916441 T ES92916441 T ES 92916441T ES 92916441 T ES92916441 T ES 92916441T ES 2171398 T3 ES2171398 T3 ES 2171398T3
- Authority
- ES
- Spain
- Prior art keywords
- viral
- nucleic acids
- viretal
- plant
- native
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
- C12N15/8203—Virus mediated transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
- C12N9/1074—Cyclomaltodextrin glucanotransferase (2.4.1.19)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/18—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with another compound as one donor, and incorporation of one atom of oxygen (1.14.18)
- C12Y114/18001—Tyrosinase (1.14.18.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/12011—Geminiviridae
- C12N2750/12022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
LA INVENCION SE DIRIGE A ACIDOS NUCLEICOS VIRALES DE PLANTAS RECOMBINANTES Y A LOS ANFITRIONES INFECTADOS POR LAS MISMAS. LOS ACIDOS NUCLEICOS VIRALES DE PLANTAS RECOMBINANTES COMPRENDEN UN PROMOTOR SUBGENOMICO VIRAL DE LA PLANTA NATIVA, AL MENOS UN PROMOTOR SUBGENOMICO VIRAL DE LA PLANTA NO NATIVA, UNA SECUENCIA QUE CODIFICA UNA PROTEINA DE RECUBRIMIENTO VIRAL DE LA PLANTA, Y OPCIONALMENTE, AL MENOS UNA SECUENCIA DE ACIDO NUCLEICO NO NATIVA QUE SE TRANSCRIBE O EXPRESA EN LA PLANTA ANFITRIONA INFECTADA. LOS ACIDOS NUCLEICOS VIRALES DE PLANTAS RECOMBINANTES SON ESTABLES, CAPACES DE INFECCIONES SISTEMICAS Y CAPACES DE UNA TRANSCRIPCION O EXPRESION ESTABLE EN LA PLANTA ANFITRIONA DE LAS SECUENCIAS DE ACIDO NUCLEICO NO NATIVAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73914391A | 1991-08-01 | 1991-08-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2171398T3 true ES2171398T3 (es) | 2002-09-16 |
Family
ID=24971018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92916441T Expired - Lifetime ES2171398T3 (es) | 1991-08-01 | 1992-07-31 | Acidos nucleicos viricos vegetales recombinantes. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0596979B1 (es) |
| JP (3) | JPH07503361A (es) |
| KR (1) | KR100238904B1 (es) |
| AT (1) | ATE212671T1 (es) |
| AU (1) | AU683412B2 (es) |
| CA (1) | CA2114636C (es) |
| DE (1) | DE69232393T2 (es) |
| DK (1) | DK0596979T3 (es) |
| ES (1) | ES2171398T3 (es) |
| WO (1) | WO1993003161A1 (es) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6660500B2 (en) | 1988-02-26 | 2003-12-09 | Large Scale Biology Corporation | Production of peptides in plants as viral coat protein fusions |
| US5922602A (en) * | 1988-02-26 | 1999-07-13 | Biosource Technologies, Inc. | Cytoplasmic inhibition of gene expression |
| US7033835B1 (en) | 1988-02-26 | 2006-04-25 | Large Scale Biology Corporation | Production of peptides in plants as viral coat protein fusions |
| US5977438A (en) * | 1988-02-26 | 1999-11-02 | Biosource Technologies, Inc. | Production of peptides in plants as viral coat protein fusions |
| US6054566A (en) | 1988-02-26 | 2000-04-25 | Biosource Technologies, Inc. | Recombinant animal viral nucleic acids |
| US6284492B1 (en) * | 1988-02-26 | 2001-09-04 | Large Scale Biology Corporation | Recombinant animal viral nucleic acids |
| GB9108386D0 (en) | 1991-04-19 | 1991-06-05 | Agricultural Genetics Co | Modified plant viruses as vectors |
| US5491076A (en) * | 1993-11-01 | 1996-02-13 | The Texas A&M University System | Expression of foreign genes using a replicating polyprotein producing virus vector |
| GB9414118D0 (en) * | 1994-07-13 | 1994-08-31 | Axis Genetics Ltd | Modified plant viruses as vectors of heterologous peptides |
| FR2722798B1 (fr) * | 1994-07-25 | 1996-09-13 | Toulouse Inst Nat Polytech | 1procede de production d'acides gras2plantes oleagineuses |
| AU702802B2 (en) | 1994-10-18 | 1999-03-04 | Scottish Crop Research Institute | Method of producing a chimeric protein |
| FR2733249B1 (fr) * | 1995-04-20 | 1997-06-06 | Biocem | Lipase gastrique de chien recombinante et polypeptides derives produits par les plantes, leurs procedes d'obtention et leurs utilisations |
| US5723755A (en) * | 1995-05-16 | 1998-03-03 | Francis E. Lefaivre | Large scale production of human or animal proteins using plant bioreactors |
| FR2736930B1 (fr) | 1995-07-17 | 1997-09-19 | Biocem | Procede de production, par des cellules vegetales, de proteines heminiques, proteines ainsi obtenues et produits contenant ces proteines |
| US5939262A (en) | 1996-07-03 | 1999-08-17 | Ambion, Inc. | Ribonuclease resistant RNA preparation and utilization |
| FR2754827B1 (fr) * | 1996-10-17 | 1998-12-24 | Biocem | Lipases pancreatiques et/ou colipases recombinantes et polypeptides dervies produits par les plantes, leurs procedes d'obtention et leurs utilisations |
| US7361331B2 (en) | 1996-10-18 | 2008-04-22 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food | Plant bioreactors |
| GB9703146D0 (en) | 1997-02-14 | 1997-04-02 | Innes John Centre Innov Ltd | Methods and means for gene silencing in transgenic plants |
| FI110323B (fi) | 1997-06-02 | 2002-12-31 | Timo Korpela | Rekombinanttikonstrukti geenin ilmentämisen lisäämiseksi kasveissa |
| NZ507093A (en) | 1998-04-08 | 2003-08-29 | Commw Scient Ind Res Org | Methods and means for reducing the phenotypic expression of a nucleic acid of interest in a plant |
| ES2336861T3 (es) * | 1998-06-22 | 2010-04-16 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food | Produccion de il-10 en biorreactor de planta de cultivo no alimenticia. |
| US7148400B1 (en) | 1999-04-20 | 2006-12-12 | Bayer Bioscience N.V. | Methods and means for delivering inhibitory RNA to plants and applications thereof |
| WO2001007613A2 (en) * | 1999-07-21 | 2001-02-01 | Large Scale Biology Corporation | Method for enhancing rna or protein production using non-native 5' untranslated sequences in recombinant viral nucleic acids |
| EP1458876A2 (en) | 2001-12-18 | 2004-09-22 | Bayer BioScience N.V. | Improved methods and means for delivering inhibitory rna to plants and applications thereof |
| DE10212892A1 (de) | 2002-03-20 | 2003-10-09 | Basf Plant Science Gmbh | Konstrukte und Verfahren zur Regulation der Genexpression |
| ATE405658T1 (de) | 2002-07-26 | 2008-09-15 | Basf Plant Science Gmbh | Neue selektionsverfahren |
| WO2005086667A2 (en) * | 2004-02-27 | 2005-09-22 | The Dow Chemical Company | High efficiency peptide production in plant cells |
| EP1874936B1 (en) | 2005-04-19 | 2013-10-30 | BASF Plant Science GmbH | Improved methods controlling gene expression |
| EP2980220A1 (en) | 2005-09-20 | 2016-02-03 | BASF Plant Science GmbH | Improved methods controlling gene expression |
| JP2007151435A (ja) * | 2005-12-02 | 2007-06-21 | Niigata Univ | デンプン集積能力の高い形質転換植物およびその製造方法 |
| CA2674499A1 (en) | 2007-02-06 | 2008-08-14 | Basf Plant Science Gmbh | Use of alanine racemase genes to confer nematode resistance to plants |
| MX2009007608A (es) | 2007-02-06 | 2009-07-27 | Basf Plant Science Gmbh | Composiciones y metodos que utilizan arn de interferencia para el control de nematodos. |
| CA2674562A1 (en) | 2007-02-08 | 2008-08-14 | Basf Plant Science Gmbh | Compositions and methods using rna interference of opr3-like gene for control of nematodes |
| US20100017910A1 (en) | 2007-02-09 | 2010-01-21 | Basf Plant Science Gmbh | Compositions and Methods Using RNA Interference of CDPK-Like For Control of Nematodes |
| WO2008110522A1 (en) | 2007-03-15 | 2008-09-18 | Basf Plant Science Gmbh | Use of nematode chitinase genes to control plant parasitic nematodes |
| BRPI0917371A2 (pt) | 2008-08-27 | 2015-11-17 | Basf Plant Science Gmbh | planta trangênica transformada com um vetor de expressão, semente, vetor de expressão, e, método para produzir uma planta trangênica resistente a nematóides. |
| DE112009003576T5 (de) | 2008-12-11 | 2012-09-06 | Basf Plant Science Gmbh | Pflanzenwurzel-spezifische Nematodenresistenz |
| CA2754956A1 (en) | 2009-03-20 | 2010-09-23 | Basf Plant Science Company Gmbh | Nematode-resistant transgenic plants |
| CA2765287C (en) | 2009-06-15 | 2018-12-11 | Bayer Bioscience N.V. | Nicotiana benthamiana plants deficient in xylosyltransferase activity |
| US20120151629A1 (en) | 2009-08-25 | 2012-06-14 | Basf Plant Science Company Gmbh | Nematode-Resistant Transgenic Plants |
| US8927812B2 (en) | 2009-12-09 | 2015-01-06 | Basf Plant Science Company Gmbh | Methods for increasing the resistance of plants to fungi by silencing the fungal SMT1-gene |
| EP2539362A1 (en) | 2010-02-23 | 2013-01-02 | BASF Plant Science Company GmbH | Nematode-resistant transgenic plants |
| CA2822004A1 (en) | 2010-12-20 | 2012-06-28 | Basf Plant Science Company Gmbh | Nematode-resistant transgenic plants |
| EP2535416A1 (en) | 2011-05-24 | 2012-12-19 | BASF Plant Science Company GmbH | Development of phytophthora resistant potato with increased yield |
| EP2551348B1 (en) | 2011-07-29 | 2014-09-24 | Icon Genetics GmbH | Production of galactosylated N-glycans in plants |
| US10196664B2 (en) | 2011-10-04 | 2019-02-05 | Icon Genetics Gmbh | Nicotiana benthamiana plants deficient in fucosyltransferase activity |
| WO2013050611A1 (en) | 2011-10-07 | 2013-04-11 | Basf Plant Science Company Gmbh | Method of producing plants having increased resistance to pathogens |
| WO2013050593A1 (en) | 2011-10-07 | 2013-04-11 | Basf Plant Science Company Gmbh | Method of producing plants having increased resistance to pathogens |
| WO2013050318A1 (en) | 2011-10-07 | 2013-04-11 | Basf Plant Science Company Gmbh | Method of producing plants having increased resistance to pathogens |
| WO2013053711A1 (en) | 2011-10-10 | 2013-04-18 | Basf Plant Science Company Gmbh | Method of producing plants having increased resistance to pathogens |
| WO2013053686A1 (en) | 2011-10-10 | 2013-04-18 | Basf Plant Science Company Gmbh | Method of producing plants having increased resistance to pathogens |
| CA2897485A1 (en) | 2013-01-29 | 2014-08-07 | Basf Plant Science Company Gmbh | Fungal resistant plants expressing hcp6 |
| US10462994B2 (en) | 2013-01-29 | 2019-11-05 | Basf Plant Science Company Gmbh | Fungal resistant plants expressing HCP7 |
| US10231397B2 (en) | 2013-01-29 | 2019-03-19 | Basf Plant Science Company Gmbh | Fungal resistant plants expressing EIN2 |
| CA2900005A1 (en) | 2013-03-08 | 2014-09-12 | Basf Plant Science Company Gmbh | Fungal resistant plants expressing mybtf |
| WO2014202463A1 (en) | 2013-06-17 | 2014-12-24 | Rheinisch-Westfälische Technische Hochschule Aachen | Method for identifying substances which prime cells for a stress response and cells for use in this method |
| CN105518136A (zh) | 2013-07-10 | 2016-04-20 | 巴斯夫欧洲公司 | 用于通过抑制CYP51基因表达来控制致植物病真菌和卵菌的RNAi |
| BR112017016688B1 (pt) | 2015-02-04 | 2024-01-23 | Basf Plant Science Company Gmbh | Método para aumentar a resistência fúngica, método para a produção de um produto e método para criar uma planta resistente a fungos |
| EP3302033A4 (en) | 2015-05-28 | 2018-10-31 | Tweed Inc. | Cannabis plants having modified expression of thca synthase |
| EP3054014A3 (en) | 2016-05-10 | 2016-11-23 | BASF Plant Science Company GmbH | Use of a fungicide on transgenic plants |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4407956A (en) * | 1981-03-13 | 1983-10-04 | The Regents Of The University Of California | Cloned cauliflower mosaic virus DNA as a plant vehicle |
| US5034322A (en) * | 1983-01-17 | 1991-07-23 | Monsanto Company | Chimeric genes suitable for expression in plant cells |
| ATE80182T1 (de) * | 1985-10-25 | 1992-09-15 | Monsanto Co | Pflanzenvektoren. |
| ATE108828T1 (de) * | 1987-02-09 | 1994-08-15 | Lubrizol Genetics Inc | Hybrides rns-virus. |
| NL9001711A (nl) * | 1989-10-03 | 1991-05-01 | Clovis Matton N V | Genetische manipulaties met recombinant dna, dat van rna virus afgeleide sequenties omvat. |
-
1992
- 1992-07-31 EP EP92916441A patent/EP0596979B1/en not_active Expired - Lifetime
- 1992-07-31 DE DE69232393T patent/DE69232393T2/de not_active Expired - Fee Related
- 1992-07-31 ES ES92916441T patent/ES2171398T3/es not_active Expired - Lifetime
- 1992-07-31 JP JP4511611A patent/JPH07503361A/ja not_active Withdrawn
- 1992-07-31 DK DK92916441T patent/DK0596979T3/da active
- 1992-07-31 KR KR1019940700361A patent/KR100238904B1/ko not_active Expired - Fee Related
- 1992-07-31 CA CA002114636A patent/CA2114636C/en not_active Expired - Fee Related
- 1992-07-31 WO PCT/US1992/006359 patent/WO1993003161A1/en not_active Ceased
- 1992-07-31 AT AT92916441T patent/ATE212671T1/de not_active IP Right Cessation
- 1992-07-31 AU AU33511/93A patent/AU683412B2/en not_active Ceased
-
2000
- 2000-07-12 JP JP2000212070A patent/JP3545683B2/ja not_active Expired - Fee Related
-
2001
- 2001-10-10 JP JP2001313207A patent/JP3316209B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP3316209B2 (ja) | 2002-08-19 |
| CA2114636A1 (en) | 1993-02-18 |
| DE69232393T2 (de) | 2002-08-29 |
| WO1993003161A1 (en) | 1993-02-18 |
| DE69232393D1 (de) | 2002-03-14 |
| KR100238904B1 (ko) | 2000-01-15 |
| EP0596979B1 (en) | 2002-01-30 |
| DK0596979T3 (da) | 2002-05-13 |
| ATE212671T1 (de) | 2002-02-15 |
| EP0596979A4 (en) | 1994-07-13 |
| JP3545683B2 (ja) | 2004-07-21 |
| JP2002171976A (ja) | 2002-06-18 |
| JPH07503361A (ja) | 1995-04-13 |
| EP0596979A1 (en) | 1994-05-18 |
| AU683412B2 (en) | 1997-11-13 |
| AU3351193A (en) | 1993-03-02 |
| JP2001054394A (ja) | 2001-02-27 |
| CA2114636C (en) | 2006-11-28 |
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