ES2176260T3 - Polipeptido proteico de membrana que tiene la funcion de mantener el crecimiento de las celulas pre-b y gen para el mismo. - Google Patents

Polipeptido proteico de membrana que tiene la funcion de mantener el crecimiento de las celulas pre-b y gen para el mismo.

Info

Publication number
ES2176260T3
ES2176260T3 ES94929665T ES94929665T ES2176260T3 ES 2176260 T3 ES2176260 T3 ES 2176260T3 ES 94929665 T ES94929665 T ES 94929665T ES 94929665 T ES94929665 T ES 94929665T ES 2176260 T3 ES2176260 T3 ES 2176260T3
Authority
ES
Spain
Prior art keywords
polypeptide
function
new
membrane protein
cell growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94929665T
Other languages
English (en)
Inventor
Toshio Hirano
Tsuneyasu Kaisho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17641696&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2176260(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2176260T3 publication Critical patent/ES2176260T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

LA INVENCION SE REFIERE A UN GEN QUE CODIFICA UN NUEVO POLIPEPTIDO DE PROTEINA DE MEMBRANA QUE TIENE LA FUNCION DE SOPORTAR EL CRECIMIENTO DE CELULA PRE-B, UN NUEVO POLIPEPTIDO DE PROTEINA DE MEMBRANA QUE TIENE LA FUNCION DE SOPORTAR EL CRECIMIENTO DE CELULA PRE-B Y SOPORTAR TODA O PARTE DE LA SECUENCIA QUE COMPRENDE 180 RESIDUOS DE AMINOACIDO, UN PROCESO PARA PRODUCIR EL NUEVO POLIPEPTIDO MEDIANTE LA TRANSFORMACION DE CELULAS HUESPED CON UN VECTOR QUE CONTIENE EL GEN ANTERIOR Y CULTIVANDO EL TRANSFORMANTE ASI OBTENIDO, Y UN ANTICUERPO MONOCLONAL QUE RECONOCE EL NUEVO POLIPEPTIDO. EL GEN ANTERIOR CODIFICA UNA PROTEINA DE MEMBRANA QUE TIENE LA FUNCION DE SOPORTAR EL CRECIMIENTO DE CELULA PRE-B. EL PROCESO DE LA INVENCION PERMITE LA PRODUCCION EN GRAN CANTIDAD DE UN NUEVO POLIPEPTIDO DE PROTEINA DE MEMBRANA UNIFORME Y LA PRODUCCION DE TAMBIEN UN ANTICUERPO MONOCLONAL QUE RECONOCE EL POLIPEPTIDO. ASI ES POSIBLE PREPARAR UN REACTIVO PARA LA IDENTIFICACION Y DIAGNOSTICO CLINICO DE ARTRITIS REUMATOIDE (RA).
ES94929665T 1993-10-15 1994-10-14 Polipeptido proteico de membrana que tiene la funcion de mantener el crecimiento de las celulas pre-b y gen para el mismo. Expired - Lifetime ES2176260T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP28162293 1993-10-15

Publications (1)

Publication Number Publication Date
ES2176260T3 true ES2176260T3 (es) 2002-12-01

Family

ID=17641696

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94929665T Expired - Lifetime ES2176260T3 (es) 1993-10-15 1994-10-14 Polipeptido proteico de membrana que tiene la funcion de mantener el crecimiento de las celulas pre-b y gen para el mismo.

Country Status (14)

Country Link
US (2) US5914252A (es)
EP (4) EP1156061B1 (es)
KR (1) KR100260873B1 (es)
CN (2) CN1056616C (es)
AT (2) ATE326483T1 (es)
AU (1) AU688801B2 (es)
DE (2) DE69431068T2 (es)
DK (1) DK0733643T3 (es)
ES (1) ES2176260T3 (es)
HK (1) HK1039623A1 (es)
PT (1) PT733643E (es)
TW (2) TW474991B (es)
WO (1) WO1995010536A1 (es)
ZA (1) ZA948016B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA943348B (en) * 1993-05-21 1995-11-16 Hirano Toshio A gene encoding a polypeptide having pre-B cell growth-supporting ability
US7049408B2 (en) * 1993-10-15 2006-05-23 Toshio Hirano Antibody reactive with a protein having pre-B cell growth-supporting ability
KR20000070989A (ko) * 1997-02-12 2000-11-25 나가야마 오사무 임파구계 종양의 치료제
EP0972524A4 (en) * 1997-02-28 2001-03-28 Chugai Pharmaceutical Co Ltd LYMPHOCYTE ACTIVATION INHIBITORS
KR20020025990A (ko) 1999-08-23 2002-04-04 나가야마 오사무 에이치엠1.24 항원의 발현 증강제
WO2001077362A1 (fr) * 2000-04-06 2001-10-18 Chugai Seiyaku Kabushiki Kaisha Dosage immunologique d'anticorps anti hm1 . 24
JP3986439B2 (ja) 2001-02-07 2007-10-03 中外製薬株式会社 造血器腫瘍の治療剤
US20080219974A1 (en) * 2002-03-01 2008-09-11 Bernett Matthew J Optimized antibodies that target hm1.24
EP1767625A4 (en) 2004-06-11 2007-12-05 Ginkgo Biomedical Res Inst Co ACTIVITY REGULATOR FOR INTERFERON-PRODUCING CELL
EP2064240A2 (en) 2006-09-18 2009-06-03 Xencor, Inc. Optimized antibodies that target hm1.24
MX2010004251A (es) * 2007-10-16 2010-08-30 Sbi Biotech Co Ltd Anticuerpo anti-bst2.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA887773B (en) * 1987-10-26 1989-07-26 Immunex Corp Interleukin-7
ZA943348B (en) * 1993-05-21 1995-11-16 Hirano Toshio A gene encoding a polypeptide having pre-B cell growth-supporting ability
KR20000070989A (ko) * 1997-02-12 2000-11-25 나가야마 오사무 임파구계 종양의 치료제

Also Published As

Publication number Publication date
ATE221082T1 (de) 2002-08-15
CN1056616C (zh) 2000-09-20
DE69431068D1 (de) 2002-08-29
EP0733643A4 (en) 1999-05-06
DE69431068T2 (de) 2003-02-13
EP1705185A3 (en) 2006-10-04
US5914252A (en) 1999-06-22
DE69434741D1 (de) 2006-06-22
CN1239518C (zh) 2006-02-01
PT733643E (pt) 2002-11-29
EP1156061A1 (en) 2001-11-21
US20020161190A1 (en) 2002-10-31
EP0733643A1 (en) 1996-09-25
AU688801B2 (en) 1998-03-19
DK0733643T3 (da) 2002-10-14
US6489126B2 (en) 2002-12-03
HK1017364A1 (en) 1999-11-19
HK1039623A1 (en) 2002-05-03
AU7863894A (en) 1995-05-04
WO1995010536A1 (en) 1995-04-20
EP1156061B1 (en) 2006-05-17
KR100260873B1 (ko) 2000-07-01
CN1135759A (zh) 1996-11-13
TW474991B (en) 2002-02-01
EP0733643B1 (en) 2002-07-24
EP1705185A2 (en) 2006-09-27
ATE326483T1 (de) 2006-06-15
EP1862474A1 (en) 2007-12-05
TW442493B (en) 2001-06-23
DE69434741T2 (de) 2007-04-26
ZA948016B (en) 1995-05-31
CN1203921A (zh) 1999-01-06

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