ES2183606T3 - Granulado de adhesivo de fibrina y procedimiento para su preparacion. - Google Patents

Granulado de adhesivo de fibrina y procedimiento para su preparacion.

Info

Publication number
ES2183606T3
ES2183606T3 ES99946186T ES99946186T ES2183606T3 ES 2183606 T3 ES2183606 T3 ES 2183606T3 ES 99946186 T ES99946186 T ES 99946186T ES 99946186 T ES99946186 T ES 99946186T ES 2183606 T3 ES2183606 T3 ES 2183606T3
Authority
ES
Spain
Prior art keywords
granulate
adhesive
fibrine
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99946186T
Other languages
English (en)
Other versions
ES2183606T5 (es
Inventor
Mirna Rapp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CSL Behring GmbH Deutschland
Original Assignee
Aventis Behring GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27218889&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2183606(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE19859611A external-priority patent/DE19859611C2/de
Priority claimed from DE1999128372 external-priority patent/DE19928372A1/de
Priority claimed from DE1999128371 external-priority patent/DE19928371A1/de
Application filed by Aventis Behring GmbH filed Critical Aventis Behring GmbH
Application granted granted Critical
Publication of ES2183606T3 publication Critical patent/ES2183606T3/es
Publication of ES2183606T5 publication Critical patent/ES2183606T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Granulado de adhesivo de fibrina capaz de deslizarse sin dificultad, caracterizado porque presenta partículas de granulado con un tamaño de partícula de más de 50 µm hasta aproximadamente 1000 µm, que contienen trombina, factor XIII, fibrinógeno y una sal de calcio.
ES99946186T 1998-12-23 1999-09-17 Granulado de adhesivo de fibrina y procedimiento para su preparacion. Expired - Lifetime ES2183606T5 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE19859611 1998-12-23
DE19859611A DE19859611C2 (de) 1998-12-23 1998-12-23 Fibrinklebergranulat und Verfahren zu dessen Herstellung
DE19928372 1999-06-21
DE1999128372 DE19928372A1 (de) 1999-06-21 1999-06-21 Brausegranulat oder Brausepulver zur Erzeugung eines zur Blutstillung geeigneten Schaumes
DE1999128371 DE19928371A1 (de) 1999-06-21 1999-06-21 Zubereitung zur Stillung von Blutungen
DE19928371 1999-06-21

Publications (2)

Publication Number Publication Date
ES2183606T3 true ES2183606T3 (es) 2003-03-16
ES2183606T5 ES2183606T5 (es) 2008-05-16

Family

ID=27218889

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99946186T Expired - Lifetime ES2183606T5 (es) 1998-12-23 1999-09-17 Granulado de adhesivo de fibrina y procedimiento para su preparacion.

Country Status (9)

Country Link
EP (1) EP1140235B2 (es)
JP (1) JP4651819B2 (es)
KR (1) KR100804434B1 (es)
AT (1) ATE222781T1 (es)
AU (1) AU754458B2 (es)
CA (1) CA2363916C (es)
DE (1) DE59902496D1 (es)
ES (1) ES2183606T5 (es)
WO (1) WO2000038752A1 (es)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19849589C1 (de) † 1998-10-27 2000-06-15 Glatt Process Technology Gmbh Fibrin-Gewebekleber-Formulierung und Verfahren zu dessen Herstellung
US6730299B1 (en) * 1999-07-21 2004-05-04 Imedex Biomateriaux Adhesive protein foam for surgical and/or therapeutic uses
DE19962221A1 (de) * 1999-10-01 2001-05-23 Glatt Process Technology Gmbh Dispersionen für Depotapplikationen
PL206194B1 (pl) * 2001-01-25 2010-07-30 Nycomed Pharma Asnycomed Pharma As Sposób wytwarzania zawiesiny cząstek fibrynogenu i trombiny, zawiesina zawierająca fibrynogen, trombinę i alkohol oraz sposób powlekania nośnika taką zawiesiną
US7052713B2 (en) 2001-02-13 2006-05-30 Nycomed Pharma As Carrier with solid fibrinogen and solid thrombin
US7923431B2 (en) 2001-12-21 2011-04-12 Ferrosan Medical Devices A/S Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostatis
US7846141B2 (en) 2002-09-03 2010-12-07 Bluesky Medical Group Incorporated Reduced pressure treatment system
JP3640655B2 (ja) * 2002-10-23 2005-04-20 一知 井上 血管新生誘導剤
GB0224986D0 (en) 2002-10-28 2002-12-04 Smith & Nephew Apparatus
CA2509914A1 (en) 2002-12-11 2004-06-24 Ferrosan A/S Gelatine-based materials as swabs
US20060051340A1 (en) * 2003-01-20 2006-03-09 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Hemostatic materials
MXPA05010692A (es) 2003-04-04 2006-04-18 Tissuemed Ltd Formulaciones que se adhieren a tejido.
AR054637A1 (es) 2004-01-30 2007-07-11 Ferrosan As Aerosoles y composiciones hemostaticas
US7909805B2 (en) 2004-04-05 2011-03-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US8062272B2 (en) 2004-05-21 2011-11-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US10058642B2 (en) 2004-04-05 2018-08-28 Bluesky Medical Group Incorporated Reduced pressure treatment system
GB0409446D0 (en) 2004-04-28 2004-06-02 Smith & Nephew Apparatus
KR20070026578A (ko) * 2004-05-21 2007-03-08 자이단호진 가가쿠오요비겟세이료호겐쿠쇼 조직 봉합제
CN101001649B (zh) 2004-07-09 2011-08-31 弗罗桑医疗设备公司 包括透明质酸的止血组合物及其制备方法
BRPI0514106A (pt) 2004-08-03 2008-05-27 Tissuemed Ltd materiais adesivos a tecidos
US9358318B2 (en) 2004-10-20 2016-06-07 Ethicon, Inc. Method of making a reinforced absorbable multilayered hemostatic wound dressing
ES2530989T3 (es) 2004-10-20 2015-03-09 Ethicon Inc Hemostático absorbible
CA2640629A1 (en) 2006-02-03 2007-08-09 Tissuemed Limited Tissue-adhesive materials
EP1837038A1 (en) * 2006-03-20 2007-09-26 Tissuemed Limited Tissue-Adhesive Formulations
WO2007099370A2 (en) * 2006-03-01 2007-09-07 Tissuemed Limited Tissue-adhesive formulations
JP4571693B2 (ja) * 2006-11-30 2010-10-27 株式会社ビーエムジー 自己分解性を有する粉体−液体及び粉体−粉体の２反応剤型の医療用接着剤
DE102007012105A1 (de) * 2007-03-13 2008-09-18 Add Advanced Drug Delivery Technologies Ltd. Pellets enthaltend pharmazeutische Substanz, Verfahren zu deren Herstellung und deren Verwendung
DE102007024220A1 (de) * 2007-05-15 2008-11-20 Aesculap Ag Blutstillendes Vlies
US20100291219A1 (en) * 2007-06-21 2010-11-18 Massachusetts Institute Of Technology Methods and compositions relating to progenitor cells
HUE049431T2 (hu) 2007-11-21 2020-09-28 Smith & Nephew Sebkötözés
US8808259B2 (en) 2007-11-21 2014-08-19 T.J. Smith & Nephew Limited Suction device and dressing
GB0722820D0 (en) 2007-11-21 2008-01-02 Smith & Nephew Vacuum assisted wound dressing
US11253399B2 (en) 2007-12-06 2022-02-22 Smith & Nephew Plc Wound filling apparatuses and methods
GB0723875D0 (en) 2007-12-06 2008-01-16 Smith & Nephew Wound management
US20130096518A1 (en) 2007-12-06 2013-04-18 Smith & Nephew Plc Wound filling apparatuses and methods
GB0803564D0 (en) 2008-02-27 2008-04-02 Smith & Nephew Fluid collection
CN102014973A (zh) 2008-02-29 2011-04-13 弗罗桑医疗设备公司 用于促进止血和/或伤口愈合的装置
GB0902816D0 (en) 2009-02-19 2009-04-08 Smith & Nephew Fluid communication path
NZ600812A (en) * 2010-01-08 2014-08-29 Profibrix Bv Dry powder fibrin sealant
US9061095B2 (en) 2010-04-27 2015-06-23 Smith & Nephew Plc Wound dressing and method of use
GB201011173D0 (en) 2010-07-02 2010-08-18 Smith & Nephew Provision of wound filler
MX337627B (es) 2010-11-25 2016-03-10 Smith & Nephew Composiciones i-ii y productos y usos de la misma.
GB201020005D0 (en) 2010-11-25 2011-01-12 Smith & Nephew Composition 1-1
RU2013155713A (ru) 2011-07-06 2015-08-20 Профибрикс Бв Составы для лечения ран
US20150159066A1 (en) 2011-11-25 2015-06-11 Smith & Nephew Plc Composition, apparatus, kit and method and uses thereof
US9056092B2 (en) * 2011-12-02 2015-06-16 Ethicon, Inc. Hemostatic bioabsorbable device with polyethylene glycol binder
WO2013131520A2 (en) 2012-03-06 2013-09-12 Ferrosan Medical Devices A/S Pressurized container containing haemostatic paste
RU2636240C2 (ru) 2012-06-12 2017-11-21 Ферросан Медикал Дивайсиз А/С Сухая гемостатическая композиция
EP2968647B1 (en) 2013-03-15 2022-06-29 Smith & Nephew plc Wound dressing sealant and use thereof
US20160120706A1 (en) 2013-03-15 2016-05-05 Smith & Nephew Plc Wound dressing sealant and use thereof
EP3010419B1 (en) 2013-06-21 2020-05-20 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
US10765774B2 (en) 2013-07-09 2020-09-08 Ethicon, Inc. Hemostatic pad assembly kit and method
JP6489485B2 (ja) 2013-12-11 2019-03-27 フェロサン メディカル デバイシーズ エイ／エス 押し出し増強因子を含んでいる乾燥組成物
ES2985799T3 (es) * 2013-12-16 2024-11-07 Univ British Columbia Partículas autoalimentadas para la propulsión a través de fluidos acuosos líquidos
CA2960309A1 (en) 2014-10-13 2016-04-21 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
RU2705905C2 (ru) 2014-12-24 2019-11-12 Ферросан Медикал Дивайсиз А/С Шприц для удерживания и смешивания первого и второго веществ
AU2016290433B2 (en) 2015-07-03 2018-05-24 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
MX384582B (es) 2015-11-06 2025-03-14 Ethicon Inc Agregados celulósicos hemostáticos compactados.
US11413335B2 (en) * 2018-02-13 2022-08-16 Guangzhou Bioseal Biotech Co. Ltd Hemostatic compositions and methods of making thereof
CN107754005B (zh) 2016-08-15 2021-06-15 广州倍绣生物技术有限公司 止血组合物及其制造方法
CN106344960B (zh) * 2016-09-20 2019-02-22 安徽思维特生物科技有限公司 利用微晶纤维素接枝改性胎牛皮胶原纤维制备的止血凝胶
ES2968412T3 (es) 2018-05-09 2024-05-09 Ferrosan Medical Devices As Método para preparar una composición hemostática
CN114246974B (zh) * 2021-12-24 2023-11-03 中国人民解放军军事科学院军事医学研究院 一种止血贴的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3105624A1 (de) * 1981-02-16 1982-09-02 Hormon-Chemie München GmbH, 8000 München Material zum abdichten und heilen von wunden
ATE13810T1 (de) * 1981-06-25 1985-07-15 Serapharm Gmbh & Co Kg Angereichertes plasmaderivat zur unterstuetzung von wundverschluss und wundabdeckung.
DE3535536A1 (de) * 1985-10-04 1987-04-09 Lentia Gmbh Verfahren zum gleichzeitigen trocknen und granulieren von extraktstoffen aus enteiweisstem kaelberblut
WO1997028832A1 (en) * 1996-02-06 1997-08-14 New Generation Medical Corporation Composition for sealing wounds
JP4024302B2 (ja) † 1996-05-17 2007-12-19 クアドラント、 ドラッグ、 デリバリー、 リミテッド 微粒子および創傷治療におけるその用途
DE19849589C1 (de) † 1998-10-27 2000-06-15 Glatt Process Technology Gmbh Fibrin-Gewebekleber-Formulierung und Verfahren zu dessen Herstellung

Also Published As

Publication number Publication date
JP4651819B2 (ja) 2011-03-16
EP1140235B1 (de) 2002-08-28
WO2000038752A1 (de) 2000-07-06
CA2363916C (en) 2010-12-07
CA2363916A1 (en) 2000-07-06
AU5863899A (en) 2000-07-31
ES2183606T5 (es) 2008-05-16
KR100804434B1 (ko) 2008-02-20
KR20010099897A (ko) 2001-11-09
AU754458B2 (en) 2002-11-14
JP2002533164A (ja) 2002-10-08
ATE222781T1 (de) 2002-09-15
EP1140235A1 (de) 2001-10-10
EP1140235B2 (de) 2007-12-19
DE59902496D1 (de) 2002-10-02

Similar Documents

Publication Publication Date Title
DE59902496D1 (de) Fibrinklebergranulat und verfahren zu dessen herstellung
PL334547A1 (en) Stabilised mixture containing fibrinogen
AU7977298A (en) Compositions containing thrombin and microfibrillar collagen, and methods for preparation and use thereof
DE59801528D1 (de) In flüssigkeit zerfallender pressling
MX9204268A (es) Una composicion para la liberacion prolongada y controlada de substancias medicamentosas y un proceso para preparar la misma.
ZA82123B (en) Material for sealing and healing of wounds
FI20001087A7 (fi) Monikomponenttiset superabsorbentit geelipartikkelit
AU6805701A (en) Preservation and storage medium for biological materials
AR024306A1 (es) Preparacion farmaceutica que contiene una neurotoxina botulinica.
HUP0001796A3 (en) Dipeptide benzamidine as a kininogenase inhibitor and pharmaceutical compositions containing them
EP1088223A4 (en) METHODS OF ANALYSIS OF FIBRINOGEN USING DRY CHEMICAL REAGENTS CONTAINING SCARIN AND MAGNETIC PARTICLES
MX208598B (es) Granulos utiles para aplicaciones de oxidacion cuando se disuelven en presencia de una fuente activa de oxigeno, y composicion blanqueadora quecomprende a dichos granulos
ATE321577T1 (de) Stabilisierte proteinzubereitungen für einen gewebekleber
BG103096A (en) Thrombin inhibitors
ZA974542B (en) New amino acid derivatives and their use as thrombin inhibitors.
HUP0002951A3 (en) Bis-aminomethylcarbonyl compounds as protease inhibitors and pharmaceutical compositions containing them
DE69415018D1 (de) Oralanzuwendende flüssige arzneizubereitung enthaltend 2-(4-isobutylphenyl)propionsäure
NZ337877A (en) Composition containing betaine, sodium cholide, sodium citrate and a calcium salt useful in the preservation of viable biological material
FR2679772B1 (fr) Emboles en particules non resorbables enrobees de materiau hemostatique.
ES2185743T3 (es) Procedimiento y dispositivo de fabricacion de composicion helada conteniendo trozos.
DE69906982D1 (de) Ibuprofen und domperidone enthaltende pharmazeutische zusammensetzungen
EP0823476A3 (en) Method for activating prothrombin to thrombin
DE60010263D1 (de) Verwendung von sulfon- und phosphonsäuren als dotierstoffe von polyanilinfilmen und aus polyanilin leitende verbundwerkstoffe
AU2837595A (en) Friction materials containing blends of organic fibrous and particulate components
ATE151295T1 (de) Zweikomponenten-fibrinkleber zur verbesserung von in-vitro befruchtung