ES2196026T3 - Uso de ndv en la fabricacion de un medicamento para tratar el cancer. - Google Patents

Uso de ndv en la fabricacion de un medicamento para tratar el cancer.

Info

Publication number
ES2196026T3
ES2196026T3 ES94916604T ES94916604T ES2196026T3 ES 2196026 T3 ES2196026 T3 ES 2196026T3 ES 94916604 T ES94916604 T ES 94916604T ES 94916604 T ES94916604 T ES 94916604T ES 2196026 T3 ES2196026 T3 ES 2196026T3
Authority
ES
Spain
Prior art keywords
ndv
manufacture
treat cancer
medicinal product
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94916604T
Other languages
English (en)
Inventor
Robert M Lorence
Kirk W Reichard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellstat Biologics Corp
Original Assignee
Wellstat Biologics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellstat Biologics Corp filed Critical Wellstat Biologics Corp
Application granted granted Critical
Publication of ES2196026T3 publication Critical patent/ES2196026T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0331—Animal model for proliferative diseases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION PROPORCIONA UN METODO DE TRATAMIENTO DE CANCER EN UN MAMIFERO QUE COMPRENDE LA ADMINISTRACION AL MAMIFERO DE UNA CANTIDAD EFECTIVA DE VIRUS, PARTICULARMENTE VIRUS DE LA ENFERMEDAD DE NEWCASTLE O OTROS PARAMIXOVIRUS. LA INVENCION ADEMAS PROPORCIONA UN METODO DE TRATAMIENTO DE CANCER EN UN MAMIFERO QUE COMPRENDE LA ADMINISTRACION DE TALES VIRUS AL MAMIFERO EN COMBINACION CON OTRO AGENTE COMO UN COMPUESTO QUIMIOTERAPEUTICO, INMUNOADYUVANTE, CITOQUINA O AGENTE INMUNOSUPRESOR. LA INVENCION PROPORCIONA ADEMAS UN METODO DE DETECCION DE CELULAS CANCERIGENAS EN UN MAMIFERO UTILIZANDO PARAMIXOVIRUS COMO UN AGENTE DE PRESENTACION Y COMO UN INDICADOR DEL CRECIMIENTO DE CELULAS CANCERIGENAS EN EL MAMIFERO.
ES94916604T 1993-04-30 1994-04-29 Uso de ndv en la fabricacion de un medicamento para tratar el cancer. Expired - Lifetime ES2196026T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5551993A 1993-04-30 1993-04-30

Publications (1)

Publication Number Publication Date
ES2196026T3 true ES2196026T3 (es) 2003-12-16

Family

ID=21998395

Family Applications (3)

Application Number Title Priority Date Filing Date
ES04017349T Expired - Lifetime ES2315595T3 (es) 1993-04-30 1994-04-29 Composiciones para tratar cancer con uso de virus.
ES94916604T Expired - Lifetime ES2196026T3 (es) 1993-04-30 1994-04-29 Uso de ndv en la fabricacion de un medicamento para tratar el cancer.
ES02026340T Expired - Lifetime ES2310580T3 (es) 1993-04-30 1994-04-29 Composiciones purificadas del virus de la enfermedad de newcastle.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES04017349T Expired - Lifetime ES2315595T3 (es) 1993-04-30 1994-04-29 Composiciones para tratar cancer con uso de virus.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES02026340T Expired - Lifetime ES2310580T3 (es) 1993-04-30 1994-04-29 Composiciones purificadas del virus de la enfermedad de newcastle.

Country Status (12)

Country Link
US (2) US7056689B1 (es)
EP (4) EP0696326B1 (es)
JP (3) JP4338781B2 (es)
AT (3) ATE401092T1 (es)
AU (1) AU699487B2 (es)
CA (1) CA2161671A1 (es)
DE (3) DE69435118D1 (es)
DK (3) DK1486211T3 (es)
ES (3) ES2315595T3 (es)
HK (1) HK1052871A1 (es)
PT (3) PT696326E (es)
WO (1) WO1994025627A1 (es)

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US7780962B2 (en) 1997-10-09 2010-08-24 Wellstat Biologics Corporation Treatment of neoplasms with RNA viruses
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US7767200B2 (en) * 2005-07-14 2010-08-03 Wellstat Biologics Corporation Cancer treatment using viruses, fluoropyrimidines and camptothecins
PL2251034T3 (pl) 2005-12-02 2018-07-31 Icahn School Of Medicine At Mount Sinai Chimeryczne wirusy prezentujące nienatywne białka powierzchniowe i zastosowania tych wirusów
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Also Published As

Publication number Publication date
AU699487B2 (en) 1998-12-03
ATE411809T1 (de) 2008-11-15
CA2161671A1 (en) 1994-11-10
EP1314431A3 (en) 2003-06-18
DK0696326T3 (da) 2003-06-23
EP1314431B1 (en) 2008-07-16
JPH09503995A (ja) 1997-04-22
EP1486211B1 (en) 2008-10-22
PT1314431E (pt) 2008-10-24
US7736640B2 (en) 2010-06-15
JP4338781B2 (ja) 2009-10-07
PT696326E (pt) 2003-08-29
PT1486211E (pt) 2009-02-02
EP0696326A1 (en) 1996-02-14
WO1994025627A1 (en) 1994-11-10
ATE236271T1 (de) 2003-04-15
AU6821394A (en) 1994-11-21
EP2009119A1 (en) 2008-12-31
ES2315595T3 (es) 2009-04-01
ES2310580T3 (es) 2009-01-16
JP2005187484A (ja) 2005-07-14
DK1314431T3 (da) 2008-11-10
US7056689B1 (en) 2006-06-06
DE69435155D1 (de) 2008-12-04
ATE401092T1 (de) 2008-08-15
JP2009149689A (ja) 2009-07-09
HK1052871A1 (en) 2003-10-03
EP1486211A1 (en) 2004-12-15
EP0696326A4 (en) 1997-08-20
DE69432409T2 (de) 2003-12-24
DK0696326T5 (da) 2003-07-14
EP0696326B1 (en) 2003-04-02
DE69435118D1 (de) 2008-08-28
DK1486211T3 (da) 2009-01-19
DE69432409D1 (de) 2003-05-08
EP1314431A2 (en) 2003-05-28
US20060216310A1 (en) 2006-09-28

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