ES2478875T3 - Proceso para preparar amidas de ácidos carboxílicos pirazólicos - Google Patents

Proceso para preparar amidas de ácidos carboxílicos pirazólicos Download PDF

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Publication number
ES2478875T3
ES2478875T3 ES11714295.0T ES11714295T ES2478875T3 ES 2478875 T3 ES2478875 T3 ES 2478875T3 ES 11714295 T ES11714295 T ES 11714295T ES 2478875 T3 ES2478875 T3 ES 2478875T3
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ES
Spain
Prior art keywords
formula
compound
preparing
pyrazolic
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11714295.0T
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English (en)
Inventor
Raphael Dumeunier
Hans Tobler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Participations AG
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Syngenta Participations AG
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Filing date
Publication date
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Application granted granted Critical
Publication of ES2478875T3 publication Critical patent/ES2478875T3/es
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Un proceso para preparar el compuesto de fórmula I**Fórmula** comprendiendo el proceso a) hacer reaccionar el compuesto de fórmula II**Fórmula** con ciclopentadieno en presencia de un nitrito de alquilo y un disolvente inerte para obtener un compuesto de fórmula**Fórmula** b) hacer reaccionar el compuesto de fórmula III en presencia de un oxidante y un disolvente inerte para obtener el compuesto de fórmula IV**Fórmula** c) hidrogenar el compuesto de fórmula IV en presencia de un catalizador metálico y un disolvente inerte en atmósfera de hidrógeno para obtener el compuesto de fórmula V**FFórmula** d) hacer reaccionar el compuesto de fórmula V en presencia de un ácido de Brönsted seguido de un agente reductor para obtener el compuesto de fórmula VI**Fórmula**

Description

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Claims (1)

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ES11714295.0T 2010-04-20 2011-04-14 Proceso para preparar amidas de ácidos carboxílicos pirazólicos Active ES2478875T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10160440 2010-04-20
EP10160440 2010-04-20
PCT/EP2011/055869 WO2011131543A1 (en) 2010-04-20 2011-04-14 Process for the preparation of pyrazole carboxylic acid amides

Publications (1)

Publication Number Publication Date
ES2478875T3 true ES2478875T3 (es) 2014-07-23

Family

ID=44080322

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11714295.0T Active ES2478875T3 (es) 2010-04-20 2011-04-14 Proceso para preparar amidas de ácidos carboxílicos pirazólicos

Country Status (12)

Country Link
US (1) US8450499B2 (es)
EP (1) EP2560957B1 (es)
JP (1) JP5684895B2 (es)
CN (1) CN102858750A (es)
AR (1) AR080924A1 (es)
BR (1) BR112012026720B1 (es)
ES (1) ES2478875T3 (es)
IL (1) IL222399A (es)
MX (1) MX2012012007A (es)
TW (1) TWI419881B (es)
UY (1) UY33342A (es)
WO (1) WO2011131543A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2012012009A (es) * 2010-04-20 2012-12-17 Syngenta Participations Ag Proceso para preparar amidas de acidos carboxilicos pirazolicos.
CN106588745B (zh) * 2016-12-02 2019-06-14 杭州百昂锐地科技有限公司 一种苯并烯氟菌唑的中间体及其制备方法和应用
CN106588668A (zh) * 2016-12-02 2017-04-26 杭州百昂锐地科技有限公司 2‑溴‑5‑硝基‑1,2,3,4‑四氢‑1,4‑桥亚甲基‑萘‑9‑酚及其制备方法
CN108003030B (zh) * 2017-11-09 2020-03-31 浙江工业大学 一种管道化连续制备5-硝基-1,4-二氢-1,4-桥亚甲基-萘的方法及装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5093347A (en) 1991-01-28 1992-03-03 Monsanto Company 3-difluoromethylpyrazolecarboxamide fungicides, compositions and use
WO1993023420A1 (en) * 1992-05-20 1993-11-25 Merck & Co., Inc. NEW 7β-SUBSTITUTED-4-AZA-5α-ANDROSTAN-3-ONES AS 5α-REDUCTASE INHIBITORS
TW200401635A (en) * 2002-07-23 2004-02-01 Yamanouchi Pharma Co Ltd 2-Cyano-4-fluoropyrrolidine derivative or salt thereof
WO2007031323A1 (en) 2005-09-16 2007-03-22 Syngenta Participations Ag. Process for the production of amides
EA014297B1 (ru) * 2005-10-25 2010-10-29 Зингента Партисипейшнс Аг Гетероциклические амиды, применимые в качестве микробиоцидов
US8637678B2 (en) * 2008-12-24 2014-01-28 Syngenta Limited Methods for the preparation of aryl amides

Also Published As

Publication number Publication date
JP2013525316A (ja) 2013-06-20
TWI419881B (zh) 2013-12-21
EP2560957B1 (en) 2014-05-07
JP5684895B2 (ja) 2015-03-18
CN102858750A (zh) 2013-01-02
BR112012026720A2 (pt) 2015-10-06
US20130041161A1 (en) 2013-02-14
AR080924A1 (es) 2012-05-16
EP2560957A1 (en) 2013-02-27
UY33342A (es) 2011-12-01
BR112012026720B1 (pt) 2018-01-30
WO2011131543A1 (en) 2011-10-27
TW201204705A (en) 2012-02-01
MX2012012007A (es) 2012-12-17
US8450499B2 (en) 2013-05-28
IL222399A (en) 2015-04-30

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