ES361975A2 - Procedimiento de preparacion de nuevos derivados del spiro (4,5) decano - Google Patents

Procedimiento de preparacion de nuevos derivados del spiro (4,5) decano

Info

Publication number: ES361975A2
Authority: ES; Spain
Prior art keywords: radical; spiro; general formula; formula; translation
Prior art date: 1964-04-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES361975A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Science Union et Cie

Original Assignee

Science Union et Cie

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1964-04-22

Filing date

1968-12-28

Publication date

1971-01-16

1968-12-28 Application filed by Science Union et Cie filed Critical Science Union et Cie

1971-01-16 Publication of ES361975A2 publication Critical patent/ES361975A2/es

Status Expired legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 2
125000003003 spiro group Chemical group 0.000 title 1
-1 chlorobenzamido Chemical group 0.000 abstract 4
CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 2
CTDQAGUNKPRERK-UHFFFAOYSA-N spirodecane Chemical compound C1CCCC21CCCCC2 CTDQAGUNKPRERK-UHFFFAOYSA-N 0.000 abstract 2
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
150000007522 mineralic acids Chemical class 0.000 abstract 1
150000007524 organic acids Chemical class 0.000 abstract 1
235000005985 organic acids Nutrition 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000003198 secondary alcohol group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Hydrogenated Pyridines (AREA)

ES361975A 1964-04-22 1968-12-28 Procedimiento de preparacion de nuevos derivados del spiro (4,5) decano Expired ES361975A2 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB16696/64A GB1100281A (en)	1964-04-22	1964-04-22	New spiro-decane derivatives and process for the preparation thereof
ES0312091A ES312091A1 (es)	1964-04-22	1965-04-21	Procedimiento de preparacion de nuevos derivados del spiro (4, 5) decano

Publications (1)

Publication Number	Publication Date
ES361975A2 true ES361975A2 (es)	1971-01-16

Family

ID=10081982

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES0312091A Expired ES312091A1 (es)	1964-04-22	1965-04-21	Procedimiento de preparacion de nuevos derivados del spiro (4, 5) decano
ES361975A Expired ES361975A2 (es)	1964-04-22	1968-12-28	Procedimiento de preparacion de nuevos derivados del spiro (4,5) decano

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
ES0312091A Expired ES312091A1 (es)	1964-04-22	1965-04-21	Procedimiento de preparacion de nuevos derivados del spiro (4, 5) decano

Country Status (9)

Country	Link
US (1)	US3399192A (es)
BE (1)	BE662817A (es)
CH (1)	CH454160A (es)
DE (1)	DE1620262C3 (es)
ES (2)	ES312091A1 (es)
FR (2)	FR1441575A (es)
GB (1)	GB1100281A (es)
NL (2)	NL6504602A (es)
SE (1)	SE307793B (es)

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US4255432A (en) *	1979-09-06	1981-03-10	Syntex (U.S.A.) Inc.	8-[2-3-Indolyl)ethyl]-1-oxa-3-,8-diazaspiro[4.5]decan-2-ones, pharmaceutical compositions thereof and methods of use thereof
ES8401072A1 (es) *	1982-11-23	1983-12-16	Faes	Procedimiento de preparacion de un nuevo espirodecano.
HU204054B (en) *	1989-08-10	1991-11-28	Richter Gedeon Vegyeszet	Process for producing new 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives and pharmaceutical compositions comprising same
YU150489A (sh) *	1989-08-10	1992-12-21	W.L. Gore & Co. Gmbh.	Uređaj za ispitivanje odevnih predmeta na nepromočivost
FR2666583B1 (fr) *	1990-09-06	1994-09-09	Adir	Nouveaux derives du spiro [4.5] decane, leur procede de preparation et leurs compositions pharmaceutiques les renfermant.
FR2734265B1 (fr) *	1995-05-17	1997-06-13	Adir	Nouveaux composes spiro heterocycliques, leur procede de preparation et les compositions pharmaceutiques les contenant
US6982251B2 (en) *	2000-12-20	2006-01-03	Schering Corporation	Substituted 2-azetidinones useful as hypocholesterolemic agents
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HU230253B1 (hu) *	2001-01-26	2015-11-30	Merck Sharp & Dohme Corp	Peroxiszóma proliferátor-aktivált receptor (PPAR) aktivátor(ok) és szterin-abszorpció inhibitor(ok) kombinációi és alkalmazásuk vaszkuláris indikációk kezelésére
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AU2002241956A1 (en) *	2001-01-26	2002-08-06	Schering Corporation	Combinations of bile acid sequestrant(s) and sterol absorption inhibitor(s) and treatments for vascular indications
PL364178A1 (en) *	2001-01-26	2004-12-13	Schering Corporation	Combinations of sterol absorption inhibitor(s) with blood modifier(s) for treating vascular conditions
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JP2004532868A (ja) *	2001-05-25	2004-10-28	シェーリング　コーポレイション	アルツハイマー病の処置におけるアゼチジノン置換誘導体の使用
DE10130020A1 (de) *	2001-06-25	2003-12-04	Gruenenthal Gmbh	Substituierte 1-Oxa-2,8-diaza-spiro[4.5]dec-2-en-derivate
DE10146275A1 (de)	2001-09-18	2003-04-24	Gruenenthal Gmbh	Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz
US7053080B2 (en) *	2001-09-21	2006-05-30	Schering Corporation	Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
JP2005504091A (ja) *	2001-09-21	2005-02-10	シェーリング　コーポレイション	ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置
US20030119808A1 (en) *	2001-09-21	2003-06-26	Schering Corporation	Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
AU2002335770B2 (en) *	2001-09-21	2005-08-18	Merck Sharp & Dohme Corp.	Methods for treating or preventing vascular inflammation using sterol absorption inhibitor(s)
US7056906B2 (en) *	2001-09-21	2006-06-06	Schering Corporation	Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
AU2003250483A1 (en)	2002-08-19	2004-03-11	Pfizer Products Inc.	Combination therapy for hyperproliferative diseases
WO2004043457A1 (en) *	2002-11-06	2004-05-27	Schering Corporation	Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
JP2006519869A (ja) *	2003-03-07	2006-08-31	シェーリング　コーポレイション	置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用
JP4589919B2 (ja)	2003-03-07	2010-12-01	シェーリングコーポレイション	高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
US7459442B2 (en)	2003-03-07	2008-12-02	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
CA2517571C (en) *	2003-03-07	2011-07-05	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
US20050037063A1 (en) *	2003-07-21	2005-02-17	Bolton Anthony E.	Combined therapies
EP1680189A2 (en) *	2003-11-05	2006-07-19	Schering Corporation	Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions
RU2006132465A (ru) *	2004-02-10	2008-03-20	Ф.Хоффманн-Ля Рош Аг (Ch)	Модуляторы хемокинового рецептора ccr5
US20060063803A1 (en) *	2004-09-23	2006-03-23	Pfizer Inc	4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
GT200600381A (es)	2005-08-25	2007-03-28		Compuestos organicos
US7741317B2 (en)	2005-10-21	2010-06-22	Bristol-Myers Squibb Company	LXR modulators
US7888376B2 (en)	2005-11-23	2011-02-15	Bristol-Myers Squibb Company	Heterocyclic CETP inhibitors
US7919506B2 (en)	2006-03-10	2011-04-05	Pfizer Inc.	Dibenzyl amine compounds and derivatives
US8383660B2 (en)	2006-03-10	2013-02-26	Pfizer Inc.	Dibenzyl amine compounds and derivatives
CN101663262B (zh)	2006-12-01	2014-03-26	百时美施贵宝公司	用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
WO2008119663A1 (en) *	2007-03-29	2008-10-09	F. Hoffmann-La Roche Ag	Heterocyclic antiviral compounds
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
MX354786B (es)	2007-06-04	2018-03-21	Synergy Pharmaceuticals Inc	Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
ES2522968T3 (es)	2008-06-04	2014-11-19	Synergy Pharmaceuticals Inc.	Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
AU2009270833B2 (en)	2008-07-16	2015-02-19	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
CN102766147B (zh) *	2012-08-03	2015-07-15	无锡药兴医药科技有限公司	一种芬司匹利及其氢卤酸盐的制备方法
AU2014235209B2 (en)	2013-03-15	2018-06-14	Bausch Health Ireland Limited	Guanylate cyclase receptor agonists combined with other drugs
AU2014235215A1 (en)	2013-03-15	2015-10-01	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
EP2986599A1 (en)	2013-04-17	2016-02-24	Pfizer Inc.	N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
BR112015030326A2 (pt)	2013-06-05	2017-08-29	Synergy Pharmaceuticals Inc	Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos
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US3193559A (en) *		1965-07-06		New derivatives of z-oxazolidinones
US2437388A (en) *		1948-03-09		Z-oxazolidone compounds and proc
US2500714A (en) *	1944-10-30	1950-03-14	Abbott Lab	4-phenyl-1-alkyl isonipecotic acid lactones
US3054794A (en) *	1958-01-17	1962-09-18	Us Vitamin Pharm Corp	Process for preparing 3-(aminoalkyl)-oxazolidine-2, 4-diones
GB974134A (en) *	1963-03-28	1964-11-04	Science Union Et Compagnie Soc	Oxazolidinone derivatives

0
- NL NL127065D patent/NL127065C/xx active
1964
- 1964-04-22 GB GB16696/64A patent/GB1100281A/en not_active Expired
1965
- 1965-03-27 SE SE4001/65A patent/SE307793B/xx unknown
- 1965-04-09 DE DE1620262A patent/DE1620262C3/de not_active Expired
- 1965-04-12 NL NL6504602A patent/NL6504602A/xx unknown
- 1965-04-14 US US447952A patent/US3399192A/en not_active Expired - Lifetime
- 1965-04-16 FR FR13521A patent/FR1441575A/fr not_active Expired
- 1965-04-21 ES ES0312091A patent/ES312091A1/es not_active Expired
- 1965-04-21 BE BE662817A patent/BE662817A/xx unknown
- 1965-04-22 CH CH558965A patent/CH454160A/fr unknown
- 1965-06-25 FR FR22211A patent/FR4463M/fr not_active Expired
1968
- 1968-12-28 ES ES361975A patent/ES361975A2/es not_active Expired

Also Published As

Publication number	Publication date
FR1441575A (fr)	1966-06-10
DE1620262C3 (de)	1980-07-03
NL6504602A (es)	1965-10-25
CH454160A (fr)	1968-04-15
DE1620262A1 (de)	1972-03-23
GB1100281A (en)	1968-01-24
ES312091A1 (es)	1965-10-01
DE1620262B2 (de)	1979-10-11
BE662817A (es)	1965-10-21
FR4463M (es)	1966-09-26
NL127065C (es)
US3399192A (en)	1968-08-27
SE307793B (es)	1969-01-20

Publication	Publication Date	Title
ES361975A2 (es)	1971-01-16	Procedimiento de preparacion de nuevos derivados del spiro (4,5) decano
ES302622A1 (es)	1965-03-16	Procedimiento para la preparacion de derivados heterociclicos.
ES334560A1 (es)	1967-11-01	Un procedimiento para la preparacion de un compuesto tetrahidro-halo-sulfamil-quinazolinonas.
ES306817A1 (es)	1965-05-16	Procedimiento para preparar un nuevo derivado de isoxazol.
ES331339A1 (es)	1967-07-01	Procedimiento para la preparacion de alquilenpiperidinas sustituidas.
GB1031367A (en)	1966-06-02	Photographic light-sensitive materials
ES440029A1 (es)	1977-02-16	Un procedimiento para preparar nuevos derivados de 2-ami- noindano.
ES295832A1 (es)	1964-06-16	Procedimiento para la preparación de antiparasitarios
ES335648A1 (es)	1967-12-16	Procedimiento para la obtencion de compuestos bencimidazolicos.
ES395701A1 (es)	1973-12-01	Procedimiento para la produccion de un compuesto de fenil- hidrazonas.
GB1042480A (en)	1966-09-14	Substituted pyridyl coumarins
ES327846A1 (es)	1967-08-01	Procedimiento para la preparacion de derivados de la isoindolobenzodiacepin-6-ona.
ES332645A1 (es)	1967-07-16	Procedimiento para la preparacion de nuevos n-heterociclos.
ES412068A1 (es)	1976-01-01	Un procedimiento para la preparacion de compuestos anaste- sicos locales.
ES311323A1 (es)	1966-01-01	Procedimiento para la preparacion de acetilencarbinoles.
ES298316A1 (es)	1964-06-01	Procedimiento para la preparación de derivados de benzoxazepina
ES334350A1 (es)	1967-10-16	Un procedimiento de diazotipia.
ES295069A1 (es)	1963-11-01	Procedimiento para la preparación de agentes para combatir los parásitos del algodón
ES317572A1 (es)	1966-07-01	Procedimiento para la preparaciën de compuestos de actividad antibiëtica
ES422351A1 (es)	1976-07-16	Un procedimiento para la preparacion de un nuevo compuesto aralquilo.
ES293872A1 (es)	1964-03-01	Un procedimiento para la preparaciën de una composiciën antihelmintica
ES332685A1 (es)	1967-07-16	Un procedimiento para la polimerizacion alcalina de lactamas con mas de seis miembros en el anillo.
ES322107A1 (es)	1966-11-16	Procedimiento para la obtenciën de derivados de 6-epi-6-desoxitetraciclinas
ES368566A1 (es)	1971-05-01	Procedimiento para la preparacion de derivados de alfa-ni- cotinoil - beta - (fenilsustituido) etileno.
ES259951A1 (es)	1960-11-16	Procedimiento de preparaciën de nuevos compuestos diazoaminos