ES410832A1 - Procedimiento para la preparacion de nuevas amidas de acido4-(4-bifenilil)-4-oxo-butirico. - Google Patents
Procedimiento para la preparacion de nuevas amidas de acido4-(4-bifenilil)-4-oxo-butirico.Info
- Publication number
- ES410832A1 ES410832A1 ES410832A ES410832A ES410832A1 ES 410832 A1 ES410832 A1 ES 410832A1 ES 410832 A ES410832 A ES 410832A ES 410832 A ES410832 A ES 410832A ES 410832 A1 ES410832 A1 ES 410832A1
- Authority
- ES
- Spain
- Prior art keywords
- corresp
- substd
- halogen
- reacting
- opt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001408 amides Chemical class 0.000 title 1
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- -1 pyrrolidino, piperidino, morpholino Chemical group 0.000 abstract 3
- QNMNMNZGJJDCSG-UHFFFAOYSA-N 3-(4-phenylphenyl)prop-2-enamide Chemical compound C1=CC(C=CC(=O)N)=CC=C1C1=CC=CC=C1 QNMNMNZGJJDCSG-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical compound C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 abstract 2
- 150000002825 nitriles Chemical class 0.000 abstract 2
- NABGULCRNBRRDQ-UHFFFAOYSA-N 5-(4-phenylphenyl)-3h-furan-2-one Chemical compound O1C(=O)CC=C1C1=CC=C(C=2C=CC=CC=2)C=C1 NABGULCRNBRRDQ-UHFFFAOYSA-N 0.000 abstract 1
- 238000005727 Friedel-Crafts reaction Methods 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 235000010290 biphenyl Nutrition 0.000 abstract 1
- 239000004305 biphenyl Substances 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229960002317 succinimide Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Procedimiento para la preparación de nuevas amidas de ácido 4-(4-bifenil)-4-oxo -butírico de la fórmula general I **fórmula** en la que R1 significa un átomo de hidrógeno o de halógeno, el grupo ciano, nitro o amino, R2 significa un átomo de hidrógeno o de halógeno, R3 y R4 , que pueden ser iguales o diferentes, significan átomos de hidrógeno, radicales alcohilo con 1 a 5 átomos de carbono eventualmente sustituidos por un grupo hidroxi o alcoxi inferior, o radicales fenilo que pueden estar sustituido por un átomo de halógeno, un grupo trifluorometilo, hidroxi, alcohilo inferior o alcoxi inferior, o R3 y R4 , juntamente con el átomo de nitrógeno, significan un radical pirrolidino, piperidino, morfolino o piperazino eventualmente sustituido por un radical alcohilo inferior, así como de sus sales fisiológicamente compatibles con ácidos orgánicos o inorgánicos, caso de que un compuesto de la fórmula general I contenga un radical básico, caracterizado porque se hace reaccionar un derivado de ácido 4-(4-bifenilil)-4-oxo-butírico
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2141925A DE2141925A1 (de) | 1971-08-20 | 1971-08-20 | Neue 4-(4-biphenylyl)-4-oxo-buttersaeureamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES410832A1 true ES410832A1 (es) | 1975-12-01 |
Family
ID=5817371
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES410833A Expired ES410833A1 (es) | 1971-08-20 | 1973-01-20 | Procedimiento para la preparacion de nuevas amidas de acido4-(4-bifenilil)-4-oxo-butirico. |
| ES410835A Expired ES410835A1 (es) | 1971-08-20 | 1973-01-20 | Procedimiento para la preparacion de nuevas amidas de acido4 - (4-bifenilil)-4-oxo-butirico. |
| ES410832A Expired ES410832A1 (es) | 1971-08-20 | 1973-01-20 | Procedimiento para la preparacion de nuevas amidas de acido4-(4-bifenilil)-4-oxo-butirico. |
| ES410837A Expired ES410837A1 (es) | 1971-08-20 | 1973-01-20 | Procedimiento para la preparacion de nuevas amidas de acido4-(4-bifenilil)-4-oxo-butirico. |
| ES410836A Expired ES410836A1 (es) | 1971-08-20 | 1973-01-20 | Procedimiento para la preparacion de nuevas amidas de acido4 - (4-bifenilil)-4-oxo-butirico. |
| ES410834A Expired ES410834A1 (es) | 1971-08-20 | 1973-01-20 | Procedimiento para la preparacion de nuevas amidas de acido4 - (4-bifenilil)-4-oxo-butirico. |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES410833A Expired ES410833A1 (es) | 1971-08-20 | 1973-01-20 | Procedimiento para la preparacion de nuevas amidas de acido4-(4-bifenilil)-4-oxo-butirico. |
| ES410835A Expired ES410835A1 (es) | 1971-08-20 | 1973-01-20 | Procedimiento para la preparacion de nuevas amidas de acido4 - (4-bifenilil)-4-oxo-butirico. |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES410837A Expired ES410837A1 (es) | 1971-08-20 | 1973-01-20 | Procedimiento para la preparacion de nuevas amidas de acido4-(4-bifenilil)-4-oxo-butirico. |
| ES410836A Expired ES410836A1 (es) | 1971-08-20 | 1973-01-20 | Procedimiento para la preparacion de nuevas amidas de acido4 - (4-bifenilil)-4-oxo-butirico. |
| ES410834A Expired ES410834A1 (es) | 1971-08-20 | 1973-01-20 | Procedimiento para la preparacion de nuevas amidas de acido4 - (4-bifenilil)-4-oxo-butirico. |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS4829749A (es) |
| AT (5) | AT323723B (es) |
| AU (1) | AU4575272A (es) |
| DD (1) | DD99990A5 (es) |
| DE (1) | DE2141925A1 (es) |
| ES (6) | ES410833A1 (es) |
| HU (1) | HU163806B (es) |
| PL (1) | PL83431B1 (es) |
| RO (1) | RO59404A (es) |
| ZA (1) | ZA725709B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51119170A (en) * | 1975-04-10 | 1976-10-19 | Shimakura Kogyosho:Kk | Process and apparatus for producing a toothbrush |
-
1971
- 1971-08-20 DE DE2141925A patent/DE2141925A1/de active Pending
-
1972
- 1972-08-10 AT AT690573A patent/AT323723B/de not_active IP Right Cessation
- 1972-08-10 AT AT690373A patent/AT323721B/de not_active IP Right Cessation
- 1972-08-10 AT AT690673A patent/AT323724B/de not_active IP Right Cessation
- 1972-08-10 AT AT690572A patent/AT318583B/de not_active IP Right Cessation
- 1972-08-10 AT AT690473A patent/AT323722B/de not_active IP Right Cessation
- 1972-08-18 RO RO71986A patent/RO59404A/ro unknown
- 1972-08-18 AU AU45752/72A patent/AU4575272A/en not_active Expired
- 1972-08-18 HU HUTO883A patent/HU163806B/hu unknown
- 1972-08-18 ZA ZA725709A patent/ZA725709B/xx unknown
- 1972-08-18 DD DD165129A patent/DD99990A5/xx unknown
- 1972-08-19 JP JP47083254A patent/JPS4829749A/ja active Pending
- 1972-08-19 PL PL1972157362A patent/PL83431B1/pl unknown
-
1973
- 1973-01-20 ES ES410833A patent/ES410833A1/es not_active Expired
- 1973-01-20 ES ES410835A patent/ES410835A1/es not_active Expired
- 1973-01-20 ES ES410832A patent/ES410832A1/es not_active Expired
- 1973-01-20 ES ES410837A patent/ES410837A1/es not_active Expired
- 1973-01-20 ES ES410836A patent/ES410836A1/es not_active Expired
- 1973-01-20 ES ES410834A patent/ES410834A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ZA725709B (en) | 1974-04-24 |
| AT323723B (de) | 1975-07-25 |
| ES410836A1 (es) | 1975-12-16 |
| JPS4829749A (es) | 1973-04-19 |
| ES410834A1 (es) | 1975-12-16 |
| DD99990A5 (es) | 1973-09-05 |
| AT323724B (de) | 1975-07-25 |
| RO59404A (es) | 1976-06-15 |
| ES410837A1 (es) | 1975-12-01 |
| ES410835A1 (es) | 1975-12-16 |
| HU163806B (es) | 1973-10-27 |
| PL83431B1 (es) | 1975-12-31 |
| AT323721B (de) | 1975-07-25 |
| DE2141925A1 (de) | 1973-03-08 |
| ES410833A1 (es) | 1975-12-01 |
| AU4575272A (en) | 1974-02-21 |
| AT318583B (de) | 1974-10-25 |
| AT323722B (de) | 1975-07-25 |
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