ES429247A1 - Halogen-pyrazole derivatives a method for producing them and medicaments containing them - Google Patents
Halogen-pyrazole derivatives a method for producing them and medicaments containing themInfo
- Publication number
- ES429247A1 ES429247A1 ES429247A ES429247A ES429247A1 ES 429247 A1 ES429247 A1 ES 429247A1 ES 429247 A ES429247 A ES 429247A ES 429247 A ES429247 A ES 429247A ES 429247 A1 ES429247 A1 ES 429247A1
- Authority
- ES
- Spain
- Prior art keywords
- general formula
- halogen
- salts
- producing
- transformed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Procedure for the preparation of halogenopyrazole derivatives and their salts with organic or inorganic bases of the general formula I ** (See formula) ** wherein Ph1 and Ph2 mean the same or different phenyl radicals and Halogen means a fluorine, chlorine or bromine atom, as well as their salts, characterized in that a compound of the general formula II is hydrolyzed ** (See formula) ** wherein Ph1, Ph2 and Halogen have the meanings indicated above, and B means a functional derivative of an acetic acid group, and optionally the compounds obtained of the general formula I are transformed into their salts or, if desired, a compound obtained from the general formula I in the form of a salt is transformed into free acid. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU68238A LU68238A1 (en) | 1973-08-16 | 1973-08-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES429247A1 true ES429247A1 (en) | 1976-08-16 |
Family
ID=19727442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES429247A Expired ES429247A1 (en) | 1973-08-16 | 1974-08-14 | Halogen-pyrazole derivatives a method for producing them and medicaments containing them |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS5230515B2 (en) |
| AT (1) | AT339892B (en) |
| BE (1) | BE818912A (en) |
| CA (1) | CA1048499A (en) |
| CH (1) | CH601250A5 (en) |
| DE (2) | DE2462459C3 (en) |
| DK (1) | DK136953B (en) |
| ES (1) | ES429247A1 (en) |
| FI (1) | FI57584C (en) |
| FR (1) | FR2240732B1 (en) |
| GB (1) | GB1475806A (en) |
| IE (1) | IE39999B1 (en) |
| LU (1) | LU68238A1 (en) |
| NL (1) | NL169070C (en) |
| NO (1) | NO140733C (en) |
| SE (1) | SE409454B (en) |
| YU (1) | YU222474A (en) |
| ZA (1) | ZA745252B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5297383A (en) * | 1976-02-13 | 1977-08-16 | Ngk Spark Plug Co | Ceramic honeycomb structures for exhaust gas purification |
| HUP0304101A3 (en) * | 2003-12-22 | 2008-10-28 | Sanofi Aventis | Pyrazole derivatives, process for producing them, their use, pharmaceutical compositions containing them and their intermediates |
-
1973
- 1973-08-16 LU LU68238A patent/LU68238A1/xx unknown
-
1974
- 1974-08-13 DE DE2462459A patent/DE2462459C3/en not_active Expired
- 1974-08-13 DE DE2438779A patent/DE2438779C3/en not_active Expired
- 1974-08-14 GB GB3574074A patent/GB1475806A/en not_active Expired
- 1974-08-14 FR FR7428162A patent/FR2240732B1/fr not_active Expired
- 1974-08-14 YU YU02224/74A patent/YU222474A/en unknown
- 1974-08-14 ES ES429247A patent/ES429247A1/en not_active Expired
- 1974-08-14 CH CH1111874A patent/CH601250A5/xx not_active IP Right Cessation
- 1974-08-15 FI FI2422/74A patent/FI57584C/en active
- 1974-08-15 IE IE1705/74A patent/IE39999B1/en unknown
- 1974-08-15 CA CA74207072A patent/CA1048499A/en not_active Expired
- 1974-08-15 DK DK438174AA patent/DK136953B/en unknown
- 1974-08-15 JP JP49093786A patent/JPS5230515B2/ja not_active Expired
- 1974-08-15 ZA ZA00745252A patent/ZA745252B/en unknown
- 1974-08-15 SE SE7410419A patent/SE409454B/en unknown
- 1974-08-15 NL NLAANVRAGE7410921,A patent/NL169070C/en not_active IP Right Cessation
- 1974-08-15 NO NO742941A patent/NO140733C/en unknown
- 1974-08-16 AT AT671174A patent/AT339892B/en not_active IP Right Cessation
- 1974-08-16 BE BE147661A patent/BE818912A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO742941L (en) | 1975-03-17 |
| NO140733C (en) | 1979-10-31 |
| DE2438779A1 (en) | 1975-02-27 |
| CH601250A5 (en) | 1978-06-30 |
| DE2462459B2 (en) | 1979-02-08 |
| DE2438779B2 (en) | 1979-01-25 |
| DE2462459C3 (en) | 1979-10-04 |
| IE39999L (en) | 1975-02-16 |
| NL7410921A (en) | 1975-02-18 |
| GB1475806A (en) | 1977-06-10 |
| FI57584B (en) | 1980-05-30 |
| AT339892B (en) | 1977-11-10 |
| FI242274A7 (en) | 1975-02-17 |
| CA1048499A (en) | 1979-02-13 |
| BE818912A (en) | 1975-02-17 |
| DE2462459A1 (en) | 1977-04-07 |
| LU68238A1 (en) | 1975-05-21 |
| DK438174A (en) | 1975-04-28 |
| NO140733B (en) | 1979-07-23 |
| JPS5049278A (en) | 1975-05-01 |
| FR2240732B1 (en) | 1978-07-21 |
| DK136953C (en) | 1978-05-29 |
| SE409454B (en) | 1979-08-20 |
| IE39999B1 (en) | 1979-02-14 |
| DK136953B (en) | 1977-12-19 |
| FI57584C (en) | 1980-09-10 |
| NL169070C (en) | 1982-06-01 |
| DE2438779C3 (en) | 1979-09-20 |
| ZA745252B (en) | 1976-03-31 |
| JPS5230515B2 (en) | 1977-08-09 |
| ATA671174A (en) | 1977-03-15 |
| SE7410419L (en) | 1975-02-17 |
| YU222474A (en) | 1983-04-27 |
| NL169070B (en) | 1982-01-04 |
| FR2240732A1 (en) | 1975-03-14 |
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