ES461101A2 - Procedimiento para preparar compuestos antagonistas de re- ceptores h-2 de histamina. - Google Patents
Procedimiento para preparar compuestos antagonistas de re- ceptores h-2 de histamina.Info
- Publication number
- ES461101A2 ES461101A2 ES461101A ES461101A ES461101A2 ES 461101 A2 ES461101 A2 ES 461101A2 ES 461101 A ES461101 A ES 461101A ES 461101 A ES461101 A ES 461101A ES 461101 A2 ES461101 A2 ES 461101A2
- Authority
- ES
- Spain
- Prior art keywords
- het
- lower alkyl
- opt
- triazolyl
- pyrazolyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000002883 imidazolyl group Chemical group 0.000 abstract 2
- 125000003226 pyrazolyl group Chemical group 0.000 abstract 2
- 125000001425 triazolyl group Chemical group 0.000 abstract 2
- -1 Heterocyclic guanidines Chemical class 0.000 abstract 1
- 102000000543 Histamine Receptors Human genes 0.000 abstract 1
- 108010002059 Histamine Receptors Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 230000001262 anti-secretory effect Effects 0.000 abstract 1
- 229940125715 antihistaminic agent Drugs 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 229940125692 cardiovascular agent Drugs 0.000 abstract 1
- 239000002327 cardiovascular agent Substances 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000001786 isothiazolyl group Chemical group 0.000 abstract 1
- 150000002541 isothioureas Chemical class 0.000 abstract 1
- 125000000842 isoxazolyl group Chemical group 0.000 abstract 1
- YECBIJXISLIIDS-UHFFFAOYSA-N mepyramine Chemical compound C1=CC(OC)=CC=C1CN(CCN(C)C)C1=CC=CC=N1 YECBIJXISLIIDS-UHFFFAOYSA-N 0.000 abstract 1
- 229960000582 mepyramine Drugs 0.000 abstract 1
- 125000002971 oxazolyl group Chemical group 0.000 abstract 1
- 125000003373 pyrazinyl group Chemical group 0.000 abstract 1
- 125000002098 pyridazinyl group Chemical group 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- IMCGHZIGRANKHV-AJNGGQMLSA-N tert-butyl (3s,5s)-2-oxo-5-[(2s,4s)-5-oxo-4-propan-2-yloxolan-2-yl]-3-propan-2-ylpyrrolidine-1-carboxylate Chemical compound O1C(=O)[C@H](C(C)C)C[C@H]1[C@H]1N(C(=O)OC(C)(C)C)C(=O)[C@H](C(C)C)C1 IMCGHZIGRANKHV-AJNGGQMLSA-N 0.000 abstract 1
- 125000001113 thiadiazolyl group Chemical group 0.000 abstract 1
- 125000000335 thiazolyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3139376 | 1976-07-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES461101A2 true ES461101A2 (es) | 1978-12-01 |
Family
ID=10322438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES461101A Expired ES461101A2 (es) | 1976-07-28 | 1977-07-28 | Procedimiento para preparar compuestos antagonistas de re- ceptores h-2 de histamina. |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5315371A (pl) |
| AU (1) | AU2734777A (pl) |
| BE (1) | BE857219R (pl) |
| DE (1) | DE2733952A1 (pl) |
| DK (1) | DK331977A (pl) |
| ES (1) | ES461101A2 (pl) |
| FI (1) | FI772294A7 (pl) |
| FR (1) | FR2359841A1 (pl) |
| IL (1) | IL52545A0 (pl) |
| LU (1) | LU77865A1 (pl) |
| NL (1) | NL7708379A (pl) |
| NO (1) | NO772669L (pl) |
| PL (1) | PL199909A1 (pl) |
| ZA (1) | ZA774221B (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4309435A (en) | 1978-10-16 | 1982-01-05 | Imperial Chemical Industries Ltd. | Antisecretory guanidine derivatives and pharmaceutical compositions containing them |
| FR2446829A1 (fr) | 1978-11-16 | 1980-08-14 | Glaxo Group Ltd | Derives de polymethylene disubstitues en alpha, omega, procede pour leur preparation et compositions pharmaceutiques les contenant |
| JPS57102852A (en) * | 1980-12-19 | 1982-06-26 | Shionogi & Co Ltd | Dicarboxylic acid diamide |
| US5352831A (en) * | 1987-09-02 | 1994-10-04 | Ciba-Geigy Corporation | Oligomeric cyanoguanidines |
| DE3866829D1 (de) * | 1987-09-02 | 1992-01-23 | Ciba Geigy Ag | Oligomere cyanoguanidine. |
| US20230349922A1 (en) | 2020-08-11 | 2023-11-02 | Université De Strasbourg | H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR735087A (fr) * | 1930-09-01 | 1932-11-03 | Anticoman Ges M B H | Procédé pour fabriquer des sels de polyméthylène-biguanidine se dissolvant facilement dans l'eau et dans le suc gastrique |
| GB1493931A (en) * | 1974-02-07 | 1977-11-30 | Smith Kline French Lab | Guanidines isothioureas and thioureas |
-
1977
- 1977-07-14 ZA ZA00774221A patent/ZA774221B/xx unknown
- 1977-07-18 IL IL52545A patent/IL52545A0/xx unknown
- 1977-07-22 DK DK331977A patent/DK331977A/da not_active Application Discontinuation
- 1977-07-26 AU AU27347/77A patent/AU2734777A/en active Pending
- 1977-07-27 DE DE19772733952 patent/DE2733952A1/de not_active Withdrawn
- 1977-07-27 NO NO772669A patent/NO772669L/no unknown
- 1977-07-27 FR FR7723081A patent/FR2359841A1/fr active Pending
- 1977-07-27 FI FI772294A patent/FI772294A7/fi not_active Application Discontinuation
- 1977-07-27 BE BE179688A patent/BE857219R/xx active
- 1977-07-28 ES ES461101A patent/ES461101A2/es not_active Expired
- 1977-07-28 LU LU77865A patent/LU77865A1/xx unknown
- 1977-07-28 NL NL7708379A patent/NL7708379A/xx not_active Application Discontinuation
- 1977-07-28 PL PL19990977A patent/PL199909A1/pl unknown
- 1977-07-28 JP JP9132577A patent/JPS5315371A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI772294A7 (pl) | 1978-01-29 |
| ZA774221B (en) | 1978-06-28 |
| DK331977A (da) | 1978-01-29 |
| IL52545A0 (en) | 1977-10-31 |
| FR2359841A1 (fr) | 1978-02-24 |
| NL7708379A (nl) | 1978-01-31 |
| DE2733952A1 (de) | 1978-02-02 |
| NO772669L (no) | 1978-01-31 |
| BE857219R (fr) | 1978-01-27 |
| AU2734777A (en) | 1979-02-01 |
| LU77865A1 (pl) | 1977-10-24 |
| PL199909A1 (pl) | 1978-11-20 |
| JPS5315371A (en) | 1978-02-13 |
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