ES464834A1 - Procedimiento para la preparacion de derivados de 2-fenil-2-hidroxietilamina. - Google Patents

Procedimiento para la preparacion de derivados de 2-fenil-2-hidroxietilamina.

Info

Publication number
ES464834A1
ES464834A1 ES464834A ES464834A ES464834A1 ES 464834 A1 ES464834 A1 ES 464834A1 ES 464834 A ES464834 A ES 464834A ES 464834 A ES464834 A ES 464834A ES 464834 A1 ES464834 A1 ES 464834A1
Authority
ES
Spain
Prior art keywords
phenyl
preparation
hydrogen
means hydrogen
hydroxyethylamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES464834A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
C.H. Boehringer Sohn AG and Co KG
Original Assignee
C.H. Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H. Boehringer Sohn AG and Co KG filed Critical C.H. Boehringer Sohn AG and Co KG
Publication of ES464834A1 publication Critical patent/ES464834A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedimiento para la preparación de derivados de 2-fenil-2-hidroxietilemina de la fórmula:(Ver fórmula)en la que R1 significa hidrógeno; halógenohidroxiaminoalcohiloalcoxi o acilamido; R2 significa hidrógenohidroxialcohiloalcoxi o carboxamido; R3 significa hidrógeno o halógenoalcohilo o alcoxi; R4 significa hidrógenometilo o etilo; y R5 y R6 significan hidrógenohalógenoalcohiloalcoxibenciloxihidroxiaminocianocarboxicarbalcoxicarboxamidoalcohilencarboxamido o acilamido; con la condición de que en el caso de que R1 signifique hidrógeno4-hidroxi o 4-cloro; R2 signifique hidrógenoR3 signifique hidrógenoR4 signifique metiloy R5 signifique hidrógeno o 2-halógenoR6 no representa 4-hidroxi o 4-benciloxien forma de racematosmezclas de racematos y antípodas ópticos individuales.
ES464834A 1976-02-17 1977-12-07 Procedimiento para la preparacion de derivados de 2-fenil-2-hidroxietilamina. Expired ES464834A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762606140 DE2606140A1 (de) 1976-02-17 1976-02-17 Neue derivate des 2-phenyl-2-hydroxyaethylamins

Publications (1)

Publication Number Publication Date
ES464834A1 true ES464834A1 (es) 1978-09-01

Family

ID=5970017

Family Applications (7)

Application Number Title Priority Date Filing Date
ES455942A Expired ES455942A1 (es) 1976-02-17 1977-02-16 Procedimiento para la preparacion de derivados de 2-fenil-2 hidroxietilamina.
ES464832A Expired ES464832A1 (es) 1976-02-17 1977-12-02 Procedimiento para la preparacion de derivados de 2-fenil-2-hidroxietilamina.
ES464833A Expired ES464833A1 (es) 1976-02-17 1977-12-07 Procedimiento para la preparacion de derivados de 2-fenil-2-hidroxietilamina.
ES464834A Expired ES464834A1 (es) 1976-02-17 1977-12-07 Procedimiento para la preparacion de derivados de 2-fenil-2-hidroxietilamina.
ES464836A Expired ES464836A1 (es) 1976-02-17 1977-12-07 Procedimiento para la preparacion de derivados de 2-fenil-2-hidroxietilamina.
ES464835A Expired ES464835A1 (es) 1976-02-17 1977-12-07 Procedimiento para la preparacion de derivados de 2-fenil-2-hidroxietilamina
ES464837A Expired ES464837A1 (es) 1976-02-17 1977-12-07 Procedimiento para la preparacion de derivados de 2-fenil-2-2hidroxietilamina.

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES455942A Expired ES455942A1 (es) 1976-02-17 1977-02-16 Procedimiento para la preparacion de derivados de 2-fenil-2 hidroxietilamina.
ES464832A Expired ES464832A1 (es) 1976-02-17 1977-12-02 Procedimiento para la preparacion de derivados de 2-fenil-2-hidroxietilamina.
ES464833A Expired ES464833A1 (es) 1976-02-17 1977-12-07 Procedimiento para la preparacion de derivados de 2-fenil-2-hidroxietilamina.

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES464836A Expired ES464836A1 (es) 1976-02-17 1977-12-07 Procedimiento para la preparacion de derivados de 2-fenil-2-hidroxietilamina.
ES464835A Expired ES464835A1 (es) 1976-02-17 1977-12-07 Procedimiento para la preparacion de derivados de 2-fenil-2-hidroxietilamina
ES464837A Expired ES464837A1 (es) 1976-02-17 1977-12-07 Procedimiento para la preparacion de derivados de 2-fenil-2-2hidroxietilamina.

Country Status (16)

Country Link
JP (1) JPS52100433A (es)
AT (1) AT355008B (es)
AU (1) AU512322B2 (es)
BE (1) BE851503A (es)
CH (4) CH634820A5 (es)
DE (1) DE2606140A1 (es)
DK (1) DK66177A (es)
ES (7) ES455942A1 (es)
FI (1) FI770170A7 (es)
FR (1) FR2341557A1 (es)
GB (1) GB1544883A (es)
IE (1) IE45186B1 (es)
LU (1) LU76774A1 (es)
NL (1) NL7701613A (es)
NO (1) NO143345C (es)
SE (1) SE7701724L (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0025331B1 (en) * 1979-09-06 1983-03-02 Beecham Group Plc Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them
DE3125870C2 (de) * 1980-07-09 1994-09-15 William John Louis 3-Aminopropoxyphenyl Derivate, ihre Herstellung und sie enthaltende Arzneimittel
EP2141154A4 (en) 2007-03-30 2011-06-01 Inst Med Molecular Design Inc OXAZOLIDINONE DERIVATIVITY WITH HEMMETIC EFFECT ON TYPE I 11-HYDROXYSTEROIDDEHYDROGENASE

Also Published As

Publication number Publication date
AT355008B (de) 1980-02-11
ES464833A1 (es) 1978-09-01
ES464836A1 (es) 1978-08-01
NL7701613A (nl) 1977-08-19
JPS52100433A (en) 1977-08-23
SE7701724L (sv) 1977-08-18
ATA67677A (de) 1979-07-15
FR2341557B1 (es) 1980-08-14
ES464837A1 (es) 1978-08-01
IE45186L (en) 1977-08-17
DK66177A (da) 1977-08-18
FI770170A7 (es) 1977-08-18
AU512322B2 (en) 1980-10-02
CH634820A5 (en) 1983-02-28
ES464832A1 (es) 1978-09-01
CH634822A5 (en) 1983-02-28
NO143345B (no) 1980-10-13
LU76774A1 (es) 1978-04-13
BE851503A (fr) 1977-08-16
CH635569A5 (en) 1983-04-15
IE45186B1 (en) 1982-07-14
CH634821A5 (en) 1983-02-28
AU2233477A (en) 1978-08-24
NO770509L (no) 1977-08-18
FR2341557A1 (fr) 1977-09-16
ES464835A1 (es) 1979-09-16
GB1544883A (en) 1979-04-25
ES455942A1 (es) 1978-11-01
NO143345C (no) 1981-01-21
DE2606140A1 (de) 1977-08-25

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19981103