ES472572A1 - Un procedimiento para la preparacion de derivados de morfi- nano 3-fenoxi-n-sustituidos levogiros - Google Patents

Un procedimiento para la preparacion de derivados de morfi- nano 3-fenoxi-n-sustituidos levogiros

Info

Publication number
ES472572A1
ES472572A1 ES472572A ES472572A ES472572A1 ES 472572 A1 ES472572 A1 ES 472572A1 ES 472572 A ES472572 A ES 472572A ES 472572 A ES472572 A ES 472572A ES 472572 A1 ES472572 A1 ES 472572A1
Authority
ES
Spain
Prior art keywords
phenoxy
manufacture
pharmaceutical preparations
preparations containing
morphinan derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES472572A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/811,233 external-priority patent/US4113729A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES472572A1 publication Critical patent/ES472572A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Un procedimiento para la preparación de derivados de morfinano 3-fenoxi-N-substituidos levogiros, de la fórmula general **(Fórmula)** en donde R es halógeno, nitro, alquilo inferior, alcoxilo inferior, hidroxilo o hidrógeno; R1 es alquilo inferior. p es un número entero comprendido entre 0 y 3 y n es un número entero comprendido entre 1 y 5 y sus sales aceptables en farmacia.
ES472572A 1976-12-06 1978-08-16 Un procedimiento para la preparacion de derivados de morfi- nano 3-fenoxi-n-sustituidos levogiros Expired ES472572A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74802276A 1976-12-06 1976-12-06
US05/811,233 US4113729A (en) 1976-12-06 1977-06-29 3-Phenoxymorphinans and derivatives thereof

Publications (1)

Publication Number Publication Date
ES472572A1 true ES472572A1 (es) 1979-02-16

Family

ID=27114858

Family Applications (3)

Application Number Title Priority Date Filing Date
ES464751A Expired ES464751A1 (es) 1976-12-06 1977-12-05 Un procedimiento para la preparacion de derivados de morfi- nano 3-3fenoxi-n-sustituidos levogiros.
ES472572A Expired ES472572A1 (es) 1976-12-06 1978-08-16 Un procedimiento para la preparacion de derivados de morfi- nano 3-fenoxi-n-sustituidos levogiros
ES472573A Expired ES472573A1 (es) 1976-12-06 1978-08-16 Un procedimiento para la preparacion de derivados de morfi- nano 3-fenoxi-n-sustituidos levogiros

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES464751A Expired ES464751A1 (es) 1976-12-06 1977-12-05 Un procedimiento para la preparacion de derivados de morfi- nano 3-3fenoxi-n-sustituidos levogiros.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES472573A Expired ES472573A1 (es) 1976-12-06 1978-08-16 Un procedimiento para la preparacion de derivados de morfi- nano 3-fenoxi-n-sustituidos levogiros

Country Status (22)

Country Link
JP (1) JPS5392776A (es)
AR (1) AR219510A1 (es)
AT (1) AT364826B (es)
AU (1) AU514827B2 (es)
CA (1) CA1088935A (es)
DE (1) DE2754062A1 (es)
DK (1) DK540977A (es)
ES (3) ES464751A1 (es)
FI (1) FI773636A7 (es)
FR (1) FR2372808A1 (es)
GB (1) GB1589792A (es)
HU (1) HU177640B (es)
IE (1) IE46003B1 (es)
IL (1) IL53532A (es)
IT (1) IT1143727B (es)
LU (1) LU78638A1 (es)
MC (1) MC1172A1 (es)
NL (1) NL7713432A (es)
NO (1) NO774155L (es)
NZ (1) NZ185860A (es)
PT (1) PT67363B (es)
SE (1) SE7713779L (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4247697A (en) * 1979-09-10 1981-01-27 Hoffmann-La Roche Inc. 3-Phenoxy morphinans and their derivatives
TW264473B (es) * 1993-01-06 1995-12-01 Hoffmann La Roche

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH560194A5 (es) * 1967-08-25 1975-03-27 Hoffmann La Roche
JPS493961B1 (es) * 1969-06-24 1974-01-29

Also Published As

Publication number Publication date
AU514827B2 (en) 1981-02-26
FR2372808B1 (es) 1981-07-10
NZ185860A (en) 1980-10-24
IL53532A (en) 1981-09-13
DK540977A (da) 1978-06-07
PT67363A (en) 1978-01-01
FR2372808A1 (fr) 1978-06-30
MC1172A1 (fr) 1978-09-25
IE46003L (en) 1978-06-06
ES472573A1 (es) 1979-02-16
ATA869277A (de) 1981-04-15
IE46003B1 (en) 1983-01-26
AR219510A1 (es) 1980-08-29
LU78638A1 (es) 1979-02-02
IL53532A0 (en) 1978-03-10
CA1088935A (en) 1980-11-04
SE7713779L (sv) 1978-06-07
FI773636A7 (fi) 1978-06-07
DE2754062A1 (de) 1978-06-08
JPS5392776A (en) 1978-08-15
HU177640B (en) 1981-11-28
ES464751A1 (es) 1978-12-16
PT67363B (en) 1979-12-17
NL7713432A (nl) 1978-06-08
AT364826B (de) 1981-11-25
IT1143727B (it) 1986-10-22
AU3126477A (en) 1979-06-14
GB1589792A (en) 1981-05-20
NO774155L (no) 1978-06-07

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