ES484702A1 - Procedimiento para producir un alergeno tratado con aldehidode baja reactividad alergenica en seres humanos alergicos - Google Patents

Procedimiento para producir un alergeno tratado con aldehidode baja reactividad alergenica en seres humanos alergicos

Info

Publication number
ES484702A1
ES484702A1 ES484702A ES484702A ES484702A1 ES 484702 A1 ES484702 A1 ES 484702A1 ES 484702 A ES484702 A ES 484702A ES 484702 A ES484702 A ES 484702A ES 484702 A1 ES484702 A1 ES 484702A1
Authority
ES
Spain
Prior art keywords
allergic
allergen
procedure
produce
humans
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES484702A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johns Hopkins University filed Critical Johns Hopkins University
Publication of ES484702A1 publication Critical patent/ES484702A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para producir un alergeno tratado con aldehído de baja reactividad alergénica en seres humanos alérgicos, y que conserva las propiedades inmunizantes deseadas del alergeno nativo dando lugar a la mejoría de la sintomatología de personas alérgicas y a la producción correspondiente de anticuerpo de bloqueo que se considera asociada con el alivio de síntomas, pero no unicamente responsable por necesidad del mismo, y que puede inducir en los animales mamíferos la formación de anticuerpos de bloqueo contra el alergeno nativo en concentración suficiente, caracterizado porque comprende dejar que los alergenos reaccionen químicamente en condiciones suaves con una solución elegida del grupo consistente en formaldehídos, aldehídos difuncionales alifáticos saturados inferiores y combinaciones de los mismos, en una pluralidad de etapas con la condición de que cualquier reacción de formaldehído se lleve a cabo en un ambiente no fenólico.
ES484702A 1978-10-04 1979-10-03 Procedimiento para producir un alergeno tratado con aldehidode baja reactividad alergenica en seres humanos alergicos Expired ES484702A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/948,409 US4234569A (en) 1978-10-04 1978-10-04 Production of aldehyde-treated allergen-containing substances

Publications (1)

Publication Number Publication Date
ES484702A1 true ES484702A1 (es) 1980-06-16

Family

ID=25487805

Family Applications (1)

Application Number Title Priority Date Filing Date
ES484702A Expired ES484702A1 (es) 1978-10-04 1979-10-03 Procedimiento para producir un alergeno tratado con aldehidode baja reactividad alergenica en seres humanos alergicos

Country Status (23)

Country Link
US (1) US4234569A (es)
JP (1) JPS55115826A (es)
AR (1) AR225616A1 (es)
AT (1) AT368006B (es)
AU (1) AU523526B2 (es)
BE (1) BE879173A (es)
CA (1) CA1122525A (es)
CH (1) CH648757A5 (es)
DE (1) DE2939557C2 (es)
DK (1) DK415279A (es)
ES (1) ES484702A1 (es)
FI (1) FI793017A7 (es)
FR (1) FR2437837A1 (es)
GB (1) GB2034585B (es)
GR (1) GR69120B (es)
IL (1) IL58238A (es)
IT (1) IT1193763B (es)
NL (1) NL7907365A (es)
NO (1) NO792968L (es)
PH (1) PH15825A (es)
PT (1) PT70244A (es)
SE (1) SE7908199L (es)
ZA (1) ZA794485B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58110240A (ja) * 1981-12-24 1983-06-30 いすゞ自動車株式会社 アスフアルトシ−ト及びその使用方法
EP0083497A3 (en) * 1982-01-06 1985-11-06 Beecham Group Plc Process for preparing modified allergens, their use in treating allergic conditions
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
US5543145A (en) * 1984-09-17 1996-08-06 Baxter International, Inc. Pharmaceutical composition and method for the suppression of factor VIII inhibitor production
US4740371A (en) * 1984-09-17 1988-04-26 International Institute Of Cellular And Molecular Pathology Treatment of allergy
US5026545A (en) * 1984-09-17 1991-06-25 Baxter International, Inc. Treatment of allergy and composition therefor
US4990336A (en) * 1989-02-08 1991-02-05 Biosearch, Inc. Sustained release dosage form
NL8900652A (nl) * 1989-03-16 1990-10-16 Leti Lab Primair-toxische stoffen of allergenen, isoleerbaar uit plantaardig materiaal, alsmede werkwijzen ter bereiding ervan en de toepassing ervan.
IT1237475B (it) * 1989-10-06 1993-06-07 Allergeni modificati chimicamente e procedimento per la loro preparazione
CA2015515C (en) 1990-01-03 1999-12-07 Jean-Marie Saint-Remy Pharmaceutical compositions containing antigen-antibody complexes and uses therefor
US5126147A (en) * 1990-02-08 1992-06-30 Biosearch, Inc. Sustained release dosage form
DE69233772D1 (de) * 1991-10-16 2009-11-12 Merck Patent Gmbh T-zell epitopen von den wichtigsten allergene von dermatophagoides (hausmilbe)
US20020090381A1 (en) * 1999-04-09 2002-07-11 H. Kim Bottomly System for controlling immune system response to antigen
GB0326439D0 (en) * 2003-11-13 2003-12-17 Imp College Innovations Ltd Methods
DE502004008649D1 (de) * 2004-09-18 2009-01-22 Protectimmun Gmbh Stallstaub-Extrakt zum Schutz vor Allergien
EP2258391A1 (en) * 2009-06-05 2010-12-08 Stallergenes S.A. Reduction of in vitro genotoxicity of pollen extracts by removal of flavonoids
MX2012009267A (es) * 2010-02-12 2013-02-07 Leti Sl Lab Proceso para producir un extracto alergenico.
GB201106802D0 (en) * 2011-04-21 2011-06-01 Allergy Therapeutics Ltd Process for preparing vaccine composition
ES2439617B1 (es) * 2012-07-20 2015-03-13 Diater Lab De Diagnostico Y Aplicaciones Terapeuticas S A Composicion para la administracion intradermica de alergoides
US20140170727A1 (en) * 2012-12-19 2014-06-19 Nanomr, Inc. Affinity medium using fixed whole cells
US11617789B2 (en) 2018-11-09 2023-04-04 Jubilant HollisterStier LLC Process for the preparation of allergenic extracts

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2019808A (en) * 1932-10-08 1935-11-05 Abbott Lab Detoxified pollen extract
US3057775A (en) * 1959-02-04 1962-10-09 Champion Co Embalming composition
US3135662A (en) * 1961-01-05 1964-06-02 Burroughs Wellcome Co Diphtheria toxoid preparation and its production
FR1604982A (en) * 1968-03-29 1972-06-26 Active protein product - with polymeric carrier
FR2035774A2 (en) * 1969-03-19 1970-12-24 Anvar Active protein product - with polymeric carrier
CH564031A5 (es) * 1968-03-29 1975-07-15 Anvar
NO132132C (es) * 1968-10-10 1975-09-24 David George Marsh
GB1282163A (en) * 1969-08-06 1972-07-19 Beecham Group Ltd Modified allergens and a process for their preparation
BE754523A (fr) * 1969-08-06 1971-02-08 Beecham Group Ltd Vaccins
JPS4935413A (es) * 1972-08-09 1974-04-02
DE2310964A1 (de) * 1973-03-02 1974-09-05 Schering Ag Antigen- bzw. antigen-proteinkonjugatbeschichtete erythrocytenpraeparation
FR2227861B1 (es) * 1973-05-04 1976-07-02 Anvar
FR2228478B1 (es) * 1973-05-08 1977-01-28 Abbott Lab
GB1492973A (en) * 1974-02-16 1977-11-23 Beecham Group Ltd Process for preparing injectable compositions
US4070455A (en) * 1974-02-16 1978-01-24 Beecham Group Limited Process for preparing injectable desensitizing compositions and products thereof in microparticle form

Also Published As

Publication number Publication date
NO792968L (no) 1980-04-09
SE7908199L (sv) 1980-04-05
GB2034585A (en) 1980-06-11
IT1193763B (it) 1988-08-24
PH15825A (en) 1983-04-08
FR2437837A1 (fr) 1980-04-30
JPS55115826A (en) 1980-09-06
CA1122525A (en) 1982-04-27
PT70244A (en) 1979-10-01
BE879173A (fr) 1980-02-01
IT7950450A0 (it) 1979-10-04
CH648757A5 (fr) 1985-04-15
GB2034585B (en) 1983-05-11
AU5111979A (en) 1980-04-17
FI793017A7 (fi) 1981-01-01
FR2437837B1 (es) 1983-10-21
ATA646179A (de) 1982-01-15
IL58238A0 (en) 1979-12-30
AT368006B (de) 1982-08-25
AU523526B2 (en) 1982-07-29
US4234569A (en) 1980-11-18
GR69120B (es) 1982-05-03
AR225616A1 (es) 1982-04-15
DK415279A (da) 1980-04-05
IL58238A (en) 1982-07-30
NL7907365A (nl) 1980-04-09
ZA794485B (en) 1980-08-27
DE2939557A1 (de) 1980-04-24
DE2939557C2 (de) 1986-10-09

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