ES537785A0 - Procedimiento para la preparacion de nuevas 2-piperazino-pteridinas - Google Patents

Procedimiento para la preparacion de nuevas 2-piperazino-pteridinas

Info

Publication number
ES537785A0
ES537785A0 ES537785A ES537785A ES537785A0 ES 537785 A0 ES537785 A0 ES 537785A0 ES 537785 A ES537785 A ES 537785A ES 537785 A ES537785 A ES 537785A ES 537785 A0 ES537785 A0 ES 537785A0
Authority
ES
Spain
Prior art keywords
group
pteridines
piperazino
new
thiomorpholino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES537785A
Other languages
English (en)
Other versions
ES8601205A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KARL mbH
Original Assignee
KARL mbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KARL mbH filed Critical KARL mbH
Publication of ES537785A0 publication Critical patent/ES537785A0/es
Publication of ES8601205A1 publication Critical patent/ES8601205A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrrole Compounds (AREA)
ES537785A 1983-07-02 1984-11-20 Procedimiento para la preparacion de nuevas 2-piperazino-pteridinas Expired ES8601205A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833323932 DE3323932A1 (de) 1983-07-02 1983-07-02 Neue 2-piperazino-pteridine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES537785A0 true ES537785A0 (es) 1985-10-16
ES8601205A1 ES8601205A1 (es) 1985-10-16

Family

ID=6203017

Family Applications (2)

Application Number Title Priority Date Filing Date
ES533298A Expired ES8503352A1 (es) 1983-07-02 1984-06-11 Procedimiento para la preparacion de 2-piperazino-pferidinas
ES537785A Expired ES8601205A1 (es) 1983-07-02 1984-11-20 Procedimiento para la preparacion de nuevas 2-piperazino-pteridinas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES533298A Expired ES8503352A1 (es) 1983-07-02 1984-06-11 Procedimiento para la preparacion de 2-piperazino-pferidinas

Country Status (17)

Country Link
EP (1) EP0134922B1 (es)
JP (1) JPS6025991A (es)
AT (1) ATE39253T1 (es)
AU (1) AU565105B2 (es)
CA (1) CA1233179A (es)
DD (1) DD229990A5 (es)
DE (2) DE3323932A1 (es)
DK (1) DK159113C (es)
ES (2) ES8503352A1 (es)
FI (1) FI80454C (es)
GB (1) GB2143232B (es)
HU (1) HU190932B (es)
IL (1) IL72265A (es)
NO (1) NO160920C (es)
NZ (1) NZ208725A (es)
PH (1) PH22493A (es)
ZA (1) ZA844968B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3445298A1 (de) * 1984-12-12 1986-06-12 Dr. Karl Thomae Gmbh, 7950 Biberach Neue pteridine, verfahren zu ihrer herstellung und deren verwendung als zwischenprodukte oder als arzneimittel
DE3540952C2 (de) * 1985-11-19 1997-08-14 Thomae Gmbh Dr K 2-Piperazino-pteridine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
DE10202468A1 (de) * 2002-01-23 2004-09-30 Faustus Forschungs Cie. Translational Cancer Research Gmbh Pteridinderivate, Verfahren zu deren Herstellung und ihre Verwendung
AU2004267885A1 (en) * 2003-08-29 2005-03-10 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
GB2407089A (en) * 2003-10-17 2005-04-20 4 Aza Bioscience Nv Pteridine derivatives
DE102004057645A1 (de) * 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057595A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057618A1 (de) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057594A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substitueirte Pteridine zur Behandlung von entzündlichen Erkrankungen
EP2029600B1 (de) * 2006-05-24 2012-03-14 Boehringer Ingelheim International GmbH Substituierte pteridine, die mit einem viergliedrigen heterocyclus substituiert sind
JP5440934B2 (ja) * 2006-05-24 2014-03-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 置換プテリジン
WO2008003149A2 (en) * 2006-07-06 2008-01-10 Gilead Sciences , Inc. Substituted pteridines for the treatment and prevention of viral infections
WO2008009078A2 (en) 2006-07-20 2008-01-24 Gilead Sciences, Inc. 4,6-dl- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
US10144736B2 (en) 2006-07-20 2018-12-04 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
US9670205B2 (en) 2015-03-04 2017-06-06 Gilead Sciences, Inc. Toll like receptor modulator compounds
AU2017318601B2 (en) 2016-09-02 2020-09-03 Gilead Sciences, Inc. Toll like receptor modulator compounds
WO2018045150A1 (en) 2016-09-02 2018-03-08 Gilead Sciences, Inc. 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
TWI751516B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202212339A (zh) 2019-04-17 2022-04-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TWI879779B (zh) 2019-06-28 2025-04-11 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2940972A (en) * 1957-06-27 1960-06-14 Thomae Gmbh Dr K Tri-and tetra-substituted pteridine derivatives
FR1352111A (fr) * 1962-01-25 1964-02-14 Lumiere Lab Triamino ptéridines et leur préparation

Also Published As

Publication number Publication date
GB8416682D0 (en) 1984-08-01
NZ208725A (en) 1988-10-28
IL72265A0 (en) 1984-10-31
DK159113C (da) 1991-02-18
PH22493A (en) 1988-09-12
ES533298A0 (es) 1985-02-16
ZA844968B (en) 1986-03-26
DE3475620D1 (en) 1989-01-19
FI80454B (fi) 1990-02-28
DE3323932A1 (de) 1985-01-10
DK316284D0 (da) 1984-06-28
CA1233179A (en) 1988-02-23
HUT34487A (en) 1985-03-28
NO842631L (no) 1985-01-03
AU3009284A (en) 1985-01-03
JPS6025991A (ja) 1985-02-08
DD229990A5 (de) 1985-11-20
ES8503352A1 (es) 1985-02-16
FI80454C (fi) 1990-06-11
GB2143232A (en) 1985-02-06
EP0134922B1 (de) 1988-12-14
IL72265A (en) 1987-08-31
HU190932B (en) 1986-12-28
DK316284A (da) 1985-01-03
FI842622A7 (fi) 1985-01-03
DK159113B (da) 1990-09-03
ATE39253T1 (de) 1988-12-15
AU565105B2 (en) 1987-09-03
NO160920C (no) 1989-06-14
FI842622A0 (fi) 1984-06-29
GB2143232B (en) 1986-11-05
EP0134922A1 (de) 1985-03-27
NO160920B (no) 1989-03-06
ES8601205A1 (es) 1985-10-16

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