ES542565A0 - Un procedimiento para la preparacion de nuevas ocfidrotiazolo (4,5-g) guinolinas. - Google Patents

Un procedimiento para la preparacion de nuevas ocfidrotiazolo (4,5-g) guinolinas.

Info

Publication number: ES542565A0
Authority: ES; Spain
Prior art keywords: sub; alkyl; ocfidrotiazolo; guinolins; procedure
Prior art date: 1984-04-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES542565A

Other languages

English (en)

Other versions

ES8704177A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-04-27

Filing date

1985-04-25

Publication date

1987-03-16

1985-04-25 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

1987-03-16 Publication of ES8704177A1 publication Critical patent/ES8704177A1/es

1987-03-16 Publication of ES542565A0 publication Critical patent/ES542565A0/es

Status Expired legal-status Critical Current

Links

125000000217 alkyl group Chemical group 0.000 abstract 3
239000002253 acid Substances 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
150000003839 salts Chemical group 0.000 abstract 2
125000004214 1-pyrrolidinyl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
125000005037 alkyl phenyl group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
229940052760 dopamine agonists Drugs 0.000 abstract 1
239000003136 dopamine receptor stimulating agent Substances 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
-1 substituted-octahydrothiazolo [4,5-g]quinolines Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/30—Metal salts; Chelates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Anesthesiology (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

ES542565A 1984-04-27 1985-04-25 Un procedimiento para la preparacion de nuevas ocfidrotiazolo (4,5-g) guinolinas. Expired ES8704177A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/604,687 US4537893A (en)	1984-04-27	1984-04-27	Octahydrothiazolo[4,5-g]quinolines and use as prolactin secretion inhibitors

Publications (2)

Publication Number	Publication Date
ES8704177A1 ES8704177A1 (es)	1987-03-16
ES542565A0 true ES542565A0 (es)	1987-03-16

Family

ID=24420601

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES542565A Expired ES8704177A1 (es)	1984-04-27	1985-04-25	Un procedimiento para la preparacion de nuevas ocfidrotiazolo (4,5-g) guinolinas.

Country Status (19)

Country	Link
US (1)	US4537893A (es)
EP (1)	EP0160502B1 (es)
JP (1)	JPH0631262B2 (es)
KR (1)	KR870001072B1 (es)
CN (1)	CN85101547A (es)
AT (1)	ATE67767T1 (es)
AU (1)	AU564946B2 (es)
CA (1)	CA1287356C (es)
DE (1)	DE3584183D1 (es)
DK (1)	DK185485A (es)
ES (1)	ES8704177A1 (es)
GR (1)	GR850989B (es)
HU (1)	HU193113B (es)
IL (1)	IL74988A0 (es)
NZ (1)	NZ211863A (es)
PH (1)	PH21951A (es)
PT (1)	PT80339B (es)
SU (1)	SU1414318A3 (es)
ZA (1)	ZA852999B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4778894A (en) *	1983-09-26	1988-10-18	Eli Lilly And Company	6 oxo-decahydroquinolines
US4977160A (en) *	1986-06-16	1990-12-11	Eli Lilly And Company	BCD tricyclic ergoline part-structure analogues
US5134143A (en) *	1986-06-16	1992-07-28	Eli Lilly And Company	BCD tricyclic ergoline part-structure analogues
US4826986A (en) *	1986-06-16	1989-05-02	Eli Lilly And Company	6-Oxo-trans-octa- and decahydroquinolines
DE3624607A1 (de) *	1986-07-21	1988-01-28	Boehringer Ingelheim Kg	Neue tetrahydrobenzothiazolo-chinoline ihre herstellung und verwendung
US4762843A (en) *	1986-09-15	1988-08-09	Warner-Lambert Company	Hetero [f] fused carbocyclic pyridines as dopaminergic agents
US5006525A (en) *	1989-07-24	1991-04-09	Eli Lilly And Company	Dopamine agonists method
US4939259A (en) *	1989-07-24	1990-07-03	Eli Lilly And Company	2-oxo-pyrido[2,3-g]quinoline derivatives
US5057515A (en) *	1989-07-24	1991-10-15	Eli Lilly And Company	Method for agonizing a dopamine receptor
US4977149A (en) *	1989-07-24	1990-12-11	Eli Lilly And Company	Pyridoquinoline dopamine agonists, compositions and use
US5416090A (en) *	1991-01-31	1995-05-16	Eli Lilly And Company	Method of treating inflammation
CA2144669A1 (en) *	1994-03-29	1995-09-30	Kozo Akasaka	Biphenyl derivatives
EP0816406B1 (de) *	1996-06-26	2000-09-06	Bayer Ag	Verfahren zur Herstellung salzarmer Präparationen von Kondensationsprodukten
WO2009139855A2 (en) *	2008-05-14	2009-11-19	Ipsen Pharma S.A.S.	Pharmaceutical compositions of somatostatin-dopamine conjugates
TWI537274B (zh) *	2011-03-14	2016-06-11	橘生藥品工業股份有限公司	新穎之八氫噻吩并喹啉衍生物、含有其之醫藥組成物及該等之用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2056224A1 (de) *	1969-11-17	1971-06-03	Danchi Seiyaku Co , Ltd , Tokio	Neue Thiazolochinohnderivate und Ver fahren zu ihrer Herstellung
US4198415A (en) *	1979-01-22	1980-04-15	Eli Lilly And Company	Prolactin inhibiting octahydro pyrazolo[3,4-g]quinolines
US4258049A (en) *	1979-07-02	1981-03-24	Smithkline Corporation	Inhibiting phenylethanolamine N-methyltransferase with thiadiazolo and oxadiazolotetrahydroisoquinolines
US4367231A (en) *	1979-09-14	1983-01-04	Eli Lilly And Company	Method of using octahydro pyrazolo[3,4-g]quinolines

1984
- 1984-04-27 US US06/604,687 patent/US4537893A/en not_active Expired - Fee Related
1985
- 1985-04-01 CN CN198585101547A patent/CN85101547A/zh active Pending
- 1985-04-22 ZA ZA852999A patent/ZA852999B/xx unknown
- 1985-04-22 NZ NZ211863A patent/NZ211863A/en unknown
- 1985-04-22 CA CA000479702A patent/CA1287356C/en not_active Expired - Lifetime
- 1985-04-22 SU SU853883101A patent/SU1414318A3/ru active
- 1985-04-23 GR GR850989A patent/GR850989B/el unknown
- 1985-04-23 IL IL74988A patent/IL74988A0/xx unknown
- 1985-04-23 PT PT80339A patent/PT80339B/pt not_active IP Right Cessation
- 1985-04-24 AT AT85302852T patent/ATE67767T1/de not_active IP Right Cessation
- 1985-04-24 DE DE8585302852T patent/DE3584183D1/de not_active Expired - Lifetime
- 1985-04-24 AU AU41666/85A patent/AU564946B2/en not_active Ceased
- 1985-04-24 EP EP85302852A patent/EP0160502B1/en not_active Expired - Lifetime
- 1985-04-25 DK DK185485A patent/DK185485A/da not_active Application Discontinuation
- 1985-04-25 ES ES542565A patent/ES8704177A1/es not_active Expired
- 1985-04-25 PH PH32196A patent/PH21951A/en unknown
- 1985-04-25 KR KR1019850002803A patent/KR870001072B1/ko not_active Expired
- 1985-04-26 JP JP60092157A patent/JPH0631262B2/ja not_active Expired - Lifetime
- 1985-04-26 HU HU851624A patent/HU193113B/hu unknown

Also Published As

Publication number	Publication date
PH21951A (en)	1988-04-15
JPH0631262B2 (ja)	1994-04-27
US4537893A (en)	1985-08-27
ATE67767T1 (de)	1991-10-15
GR850989B (es)	1985-11-25
DK185485D0 (da)	1985-04-25
ES8704177A1 (es)	1987-03-16
JPS60233091A (ja)	1985-11-19
PT80339B (en)	1987-02-16
IL74988A0 (en)	1985-08-30
DK185485A (da)	1985-10-28
KR870001072B1 (ko)	1987-05-27
DE3584183D1 (de)	1991-10-31
HUT37624A (en)	1986-01-23
HU193113B (en)	1987-08-28
EP0160502A2 (en)	1985-11-06
EP0160502A3 (en)	1987-03-11
AU564946B2 (en)	1987-09-03
PT80339A (en)	1985-05-01
KR850007261A (ko)	1985-12-02
CN85101547A (zh)	1987-01-24
SU1414318A3 (ru)	1988-07-30
CA1287356C (en)	1991-08-06
ZA852999B (en)	1986-11-26
AU4166685A (en)	1985-10-31
NZ211863A (en)	1987-10-30
EP0160502B1 (en)	1991-09-25

Legal Events

Date	Code	Title	Description
1997-07-16	FD1A	Patent lapsed	Effective date: 19970612

Publication	Publication Date	Title
DE3584183D1 (de)	1991-10-31	Octahydrothiazolo(4,5-g)chinoline.
KR830005187A (ko)	1983-08-03	아미노사이클로펜탄 알케노산 및 에스테르의 제조방법
ES541557A0 (es)	1985-12-01	Un procedimiento para la preparacion de nuevos derivados de 8-cloro-1,5-benzotiazepina
DE3687288D1 (de)	1993-01-28	Chinuclidinderivate.
KR850001171A (ko)	1985-03-16	퀴놀린 화합물의 제조방법
ES8406440A1 (es)	1984-07-01	Procedimiento para preparar derivados de 2-amino-3-acilamino-6-bencilamino-piridina
ES8604547A1 (es)	1986-02-01	Procedimiento para preparar nuevos derivados de acidos feni-laceticos
SE8302347L (sv)	1983-10-28	Bensoazacykloalkyl-spiro-imidazolidiner, framstellning derav och farmaceutiska kompositioner innehallande dem
ES8601201A1 (es)	1985-10-16	Procedimiento para preparar derivados de imidazolina
ES529069A0 (es)	1984-10-01	Procedimiento de preparar nuevos derivados de sales inertes de hidroxido de aminopiridinio y sus sales correspondientes
KR840004422A (ko)	1984-10-15	사이프로헵타딘-3-카복실산의 에스테르 및 관련 화합물의 제조방법
ES533320A0 (es)	1985-08-01	Procedimiento para preparar 1-acetonil-2-(fenilimino)-imidazolidinas
ES8308325A1 (es)	1983-08-16	"procedimiento para la preparacion de benzotriazoles".
ES515106A0 (es)	1983-11-01	"procedimiento para la preparacion de compuestos de 1-fenilindazol-3-ona".
ES8106517A1 (es)	1981-08-01	Procedimiento para la preparacion de nuevos derivados de 10-halogen-e-homo-eburnanos.
KR860001815A (ko)	1986-03-22	옥타하이드로-옥사졸로[4,5-g]퀴놀린의 제조방법
ES8500924A1 (es)	1984-11-01	Procedimiento para la preparacion de derivados de acido fenilacetico
DK469285A (da)	1986-04-19	Thiadiazolderivater, der indvirker paa centralnervesystemet, fremgangsmaade til fremstilling deraf og midler indeholdende derivaterne
AU2508584A (en)	1984-09-06	N-arylpiperazine derivatives
KR850004760A (ko)	1985-07-27	이미다조 퀴놀린 유도체의 제조방법
ES2007339A6 (es)	1989-06-16	Procedimiento para preparar nueevos derivados de ergoleno halogenados.
RU95117134A (ru)	1997-09-27	Производное морфолина или его фармацевтически приемлемая соль и фармацевтическая композиция на его основе
ES8607331A1 (es)	1986-05-16	Procedimiento para preparar derivados de oxazafosforina
RU94012551A (ru)	1996-01-20	Бензамидные производные, способы их получения, фармацевтическая композиция и способ лечения
KR850002479A (ko)	1985-05-13	피리미도 [4,5-g] 퀴놀린 유도체의 제조방법