ES550106A0 - Un procedimiento para preparar heteroarilpiperazinas biciclicas. - Google Patents

Un procedimiento para preparar heteroarilpiperazinas biciclicas.

Info

Publication number
ES550106A0
ES550106A0 ES550106A ES550106A ES550106A0 ES 550106 A0 ES550106 A0 ES 550106A0 ES 550106 A ES550106 A ES 550106A ES 550106 A ES550106 A ES 550106A ES 550106 A0 ES550106 A0 ES 550106A0
Authority
ES
Spain
Prior art keywords
compounds
heteroarilpiperazines
procedure
bicycle
prepare
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES550106A
Other languages
English (en)
Other versions
ES8704348A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duphar International Research BV
Original Assignee
Duphar International Research BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar International Research BV filed Critical Duphar International Research BV
Publication of ES550106A0 publication Critical patent/ES550106A0/es
Publication of ES8704348A1 publication Critical patent/ES8704348A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18—Benzotriazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Peptides Or Proteins (AREA)
  • Indole Compounds (AREA)
  • Furan Compounds (AREA)
ES550106A 1984-12-21 1985-12-18 Un procedimiento para preparar heteroarilpiperazinas biciclicas. Expired ES8704348A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8403918 1984-12-21

Publications (2)

Publication Number Publication Date
ES550106A0 true ES550106A0 (es) 1987-04-01
ES8704348A1 ES8704348A1 (es) 1987-04-01

Family

ID=19844955

Family Applications (2)

Application Number Title Priority Date Filing Date
ES550106A Expired ES8704348A1 (es) 1984-12-21 1985-12-18 Un procedimiento para preparar heteroarilpiperazinas biciclicas.
ES557359A Expired ES8802516A1 (es) 1984-12-21 1987-01-29 Un procedimiento para preparar derivados de piperazina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES557359A Expired ES8802516A1 (es) 1984-12-21 1987-01-29 Un procedimiento para preparar derivados de piperazina

Country Status (14)

Country Link
US (1) US4782061A (es)
EP (2) EP0190472B1 (es)
JP (2) JPS61152662A (es)
AT (1) ATE44528T1 (es)
AU (2) AU589387B2 (es)
DE (1) DE3571436D1 (es)
DK (2) DK589985A (es)
ES (2) ES8704348A1 (es)
GR (2) GR853065B (es)
IE (1) IE58916B1 (es)
IL (1) IL77396A (es)
NZ (2) NZ214611A (es)
PH (2) PH22040A (es)
ZA (2) ZA859662B (es)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190472B1 (en) * 1984-12-21 1989-07-12 Duphar International Research B.V New pharmaceutical compositions having anti-psychotic properties
EP0189612B1 (en) * 1984-12-21 1992-11-04 Duphar International Research B.V New pharmaceutical compositions having a psychotropic activity
DE3855147D1 (de) * 1987-07-20 1996-05-02 Duphar Int Res 8,9-Anellierte 1,2,3,4-Tetrahydro-beta-carbolin-Derivate
US5328905A (en) * 1987-07-20 1994-07-12 Duphar International Research B.V. 8,9-anellated-1,2,3,4-tetrahydro-β-carboline derivatives
IE74200B1 (en) * 1987-09-11 1997-07-16 Duphar Int Res Anxiolytically active piperazine derivatives
US4992441A (en) * 1987-10-14 1991-02-12 Mcneilab, Inc. 1-[[5-[[4-substituted-1-piperazinyl]methyl]-pyrrol-2-yl or furan-2-yl]methyl-2-piperidinones useful in treating schizophrenia
IL92544A0 (en) * 1988-12-08 1990-08-31 Duphar Int Res Piperazine derivatives,their preparation and pharmaceutical compositions containing them
GB8830312D0 (en) * 1988-12-28 1989-02-22 Lundbeck & Co As H Heterocyclic compounds
EP0380155A1 (en) * 1989-01-19 1990-08-01 Duphar International Research B.V 8,9-Annelated-1,2,3,4-tetrahydro-beta-carboline derivatives
EP0398413A1 (en) * 1989-05-16 1990-11-22 Duphar International Research B.V "3,4-dehydropiperidine derivatives having psychotropic activity
US5296497A (en) * 1989-05-16 1994-03-22 Duphar International Research B.V. 3,4-dehydropiperidine derivatives having psychotropic activity
FR2670491B1 (fr) * 1990-12-14 1993-02-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant.
US5569659A (en) * 1991-09-11 1996-10-29 Mcneilab, Inc. 4-arylpiperazines and 4-arylpiperidines
IE914218A1 (en) * 1991-09-11 1993-03-24 Mcneilab Inc Novel 4-arylpiperazines and 4-arylpiperidines
GB9200293D0 (en) * 1992-01-08 1992-02-26 Wyeth John & Brother Ltd Piperazine derivatives
FR2692264B1 (fr) * 1992-06-12 1994-08-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
DE4219973A1 (de) * 1992-06-19 1993-12-23 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US5314885A (en) * 1992-09-11 1994-05-24 Mcneilab, Inc. Cyclic benzylamino, benzylamido, and benzylimido antipsychotic agents
US5436246A (en) * 1992-09-17 1995-07-25 Merrell Dow Pharmaceuticals Inc. Serotonin receptor agents
DK148392D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocykliske forbindelser
HU213569B (en) * 1992-12-21 1997-08-28 Duphar Int Res Enzymatic process for the stereoselective preparation of a heterobicyclic alcohol enantiomer
EP0939135A1 (en) * 1992-12-21 1999-09-01 Duphar International Research B.V Substantially pure hetero-bicyclic alcohol enantiomers
US5395936A (en) * 1993-06-04 1995-03-07 Manzo; Ruben H. 7-(4-[4-aminophenyl)sulphonyl]-1-piperazinyl fluorquinolonic derivatives and synthesis
RU2118322C1 (ru) * 1993-07-05 1998-08-27 Дюфар Интернэшнл Рисерч Б.В. 2,3-дигидро-1,4-бензодиокси-5-ил-пиперазиновые производные или их соли
DE4341403A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
GB9408872D0 (en) * 1994-05-03 1994-06-22 Zeneca Ltd Heterocyclic compounds
FI970310L (fi) * 1994-07-26 1997-01-24 Pfizer 4-indolijohdannaiset serotoniinin vaikuttaja- ja vastavaikuttaja-aineina
DE69534213T2 (de) * 1994-10-25 2006-01-12 Astrazeneca Ab Therapeutisch wirksame Heterocyclen
US5998444A (en) * 1995-10-24 1999-12-07 Zeneca Ltd. Piperidinyl compounds as NK1 or NK2 antagonists
US6008223A (en) * 1994-10-27 1999-12-28 Zeneca Limited Therapeutic compounds
GB9508786D0 (en) * 1995-04-29 1995-06-21 Zeneca Ltd Substituted heterocycles
GB9523526D0 (en) * 1995-11-17 1996-01-17 Zeneca Ltd Therapeutic compounds
JP3989554B2 (ja) * 1996-03-29 2007-10-10 デユフアー・インターナシヨナル・リサーチ・ベー・ブイ ピペラジンおよびピペリジン化合物
TW530054B (en) * 1997-09-24 2003-05-01 Duphar Int Res New piperazine and piperidine compounds
FR2769312B1 (fr) * 1997-10-03 1999-12-03 Adir Nouveaux composes de l'indanol, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
UA71590C2 (en) * 1998-11-13 2004-12-15 Duphar Int Res Piperazine and piperidine derivatives
US20030186838A1 (en) * 2000-05-12 2003-10-02 Feenstra Roelof W. Use of compounds having combined dopamine d2, 5-ht1a and alpha adrenoreceptor agonistic action for treating cns disorders
EP1283838B1 (en) 2000-05-12 2003-12-03 Solvay Pharmaceuticals B.V. Piperazine and piperidine compounds
AR034206A1 (es) * 2001-02-16 2004-02-04 Solvay Pharm Bv Un procedimiento para la preparacion de mesilatos de derivados de piperazina y dichos mesilatos
ES2323451T7 (es) 2001-07-20 2011-08-01 Psychogenics Inc. Tratamiento para el trastorno de hiperactividad con deficit de atencion.
US9066903B2 (en) 2006-02-28 2015-06-30 The United States Of America As Represented By The Department Of Veterans Affairs Pharmacological treatment of Parkinson's disease
JP2008075402A (ja) * 2006-09-25 2008-04-03 Jfe Metal Products & Engineering Inc 防護柵用ブラケット及び防護柵
PL392436A1 (pl) 2010-09-17 2012-03-26 Adamed Spółka Z Ograniczoną Odpowiedzialnością Pochodne arylosulfonamidów do leczenia chorób odśrodkowego układu nerwowego
CN103380129B (zh) * 2010-12-20 2016-04-20 阿克图拉姆生命科学股份公司 2-甲酰胺-4-哌嗪基-苯并呋喃衍生物

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2037852C3 (de) * 1970-07-30 1980-06-26 Boehringer Sohn Ingelheim Neue Piperazinderivate und Verfahren zu ihrer Herstellung
US4118572A (en) * 1974-01-04 1978-10-03 Hoffmann-La Roche Inc. Dibenz(b,f)oxepin derivatives
US4062870A (en) * 1974-05-31 1977-12-13 Beecham Group Limited Chroman derivatives
US4091101A (en) * 1977-06-15 1978-05-23 Merck & Co., Inc. 6-(1-Piperazinyl)quinoxaline
US4404383A (en) * 1979-07-31 1983-09-13 The Quaker Oats Company N,N'-Bis[5-hydroxymethylfurfuryl]piperazine
NL8005133A (nl) * 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met antiagressieve werking.
JPS5777676A (en) * 1980-10-31 1982-05-15 Otsuka Pharmaceut Co Ltd Carbostyril derivative
KR880001634B1 (ko) * 1980-12-18 1988-09-03 오쯔까 세이야꾸 가부시끼가이샤 벤조 헤테로사이클릭 화합물의 제조방법
CH653021A5 (fr) * 1981-04-24 1985-12-13 Delalande Sa Derives piperidino, piperazino et homopiperazino, n-substitues par un groupe heterocyclique aromatique, leur procede de preparation et composition therapeutique les contenant.
US4355031A (en) * 1981-05-11 1982-10-19 American Home Products Corp. 2,3-Dihydro-3-[4-(substituted)-1-piperazinyl]-1H-isoindol-1-ones
US4426380A (en) * 1981-10-28 1984-01-17 Ciba-Geigy Corporation Benzofuran-2-ones and pharmaceutical compositions
JPS5883677A (ja) * 1981-11-11 1983-05-19 Otsuka Pharmaceut Co Ltd カルボスチリル誘導体
JPS5888314A (ja) * 1981-11-20 1983-05-26 Otsuka Pharmaceut Co Ltd 強心剤
JPS5955878A (ja) * 1982-09-24 1984-03-31 Chugai Pharmaceut Co Ltd 新規なフエニルピペラジン誘導体
EP0106800A1 (de) * 1982-10-08 1984-04-25 Ciba-Geigy Ag Furane
AU577802B2 (en) * 1983-10-17 1988-10-06 Duphar International Research B.V. Blood-pressure lowering piperazine derivatives
EP0189612B1 (en) * 1984-12-21 1992-11-04 Duphar International Research B.V New pharmaceutical compositions having a psychotropic activity
EP0190472B1 (en) * 1984-12-21 1989-07-12 Duphar International Research B.V New pharmaceutical compositions having anti-psychotic properties

Also Published As

Publication number Publication date
DK589985D0 (da) 1985-12-18
DE3571436D1 (en) 1989-08-17
DK589985A (da) 1986-06-22
AU5139085A (en) 1986-07-17
GR853065B (es) 1986-04-09
IL77396A (en) 1990-02-09
JPS61152666A (ja) 1986-07-11
EP0190472A1 (en) 1986-08-13
ES557359A0 (es) 1988-07-16
ZA859662B (en) 1986-08-27
EP0185429A1 (en) 1986-06-25
AU589387B2 (en) 1989-10-12
US4782061A (en) 1988-11-01
NZ214611A (en) 1988-06-30
IE853218L (en) 1986-06-21
PH23958A (en) 1990-01-23
EP0190472B1 (en) 1989-07-12
DK590085A (da) 1986-06-22
JPS61152662A (ja) 1986-07-11
ZA859664B (en) 1986-08-27
ES8802516A1 (es) 1988-07-16
AU5139285A (en) 1986-06-26
GR853063B (es) 1986-04-09
PH22040A (en) 1988-05-13
DK590085D0 (da) 1985-12-18
ATE44528T1 (de) 1989-07-15
IE58916B1 (en) 1993-12-01
ES8704348A1 (es) 1987-04-01
NZ214612A (en) 1988-06-30

Similar Documents

Publication Publication Date Title
ES550106A0 (es) Un procedimiento para preparar heteroarilpiperazinas biciclicas.
DK153943C (da) Fremgangsmaade til fremstilling af 1-hydroxyvitamin-d-forbindelser ud fra 1-hydroxy-3,5-cyclovitamin-d-forbindelser
ES542321A0 (es) Un procedimiento para la preparacion de derivados de la 2 pirimidinil-1-piperazina
ES478687A1 (es) Un procedimiento para la preparacion de derivados de acido carbamico.
NO854996L (no) Fremgangsmaate for fremstilling av hydrokarboner fra hetero-substituerte metaner.
ES557152A0 (es) Un procedimiento para preparar laudanos
ES525786A0 (es) Un procedimiento para preparar derivados de pirazolo (3,4-b) piridina
IT1207498B (it) Procedimento per la preparazione di composizioni plasto-elastomeriche poliolefiniche, mediante vulcanizzazione dinamica.
DE3060165D1 (en) Process for the stereospecific preparation of compounds of the vitamin k1- and k2-series, as well as new starting materials for the process
IT8420358A0 (it) Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti.
ES2012519A6 (es) Procedimiento para preparar compuestos polifluorados.
ES528152A0 (es) Un procedimiento para preparar derivados de acido 4,7-dihidropirazolo (3,4-b)piridin-5-carboxilico
SE8404334L (sv) 16-fluoro-16,17-didehydro-prostanoider och forfarande for deras framstellning
BG44203A3 (en) Method for preparing of 2- oxyindol- 1- carboxamides
RO92377A (ro) Procedeu pentru prepararea 8-halo-5,6-dialcoxichinazoli-2,4-dionelor
ES520843A0 (es) Procedimiento para la obtencion de nuevos derivados del indolizino (8,7-b 7-indol.
EP0200132A3 (en) (aminoalkylthio)hydroxydibenzoxepins, a process for their preparation and their use as medicaments
EP0141354A3 (en) Compounds useful for combatting swine dysentery and as growth promoting factors, method for the preparation thereof and compositions containing them
FI864736A7 (fi) Menetelmä 2-substituoitujen 5-nitroso-4,6-diamino-pyrimidiinien valmistamiseksi.
ZA845668B (en) Novel process for the preparation of steffimycinone analogs,novel steffimycione analogs thus obtained,novel intermediates which can be used for the synthesis of these compounds,and use of these compounds as antibacterials and for the synthesis of antitumor agents
IT8341518A0 (it) Procedimento per la preparazione di derivati dell'acido 1,1'-dinaftil-4,4',5,5',8,8'-esacarbossilico.
IT8223177A0 (it) Procedimento per la preparazione dell'acido 1,4-dimetil-pirrol-5-(p-clorobenzoil)-2-acetico.
DK146084A (da) Fremgangsmaade til fremstilling af melasseholdige, mineralske blandingsfoderstoffer