ES551203A0 - Procedimiento para preparar 17 beta-acetoxi-8,13-expoxi-ialfa.6beta,9alfa-trihidroxilabol-14-en-11-ona,sus compuestos analogos y derivados. - Google Patents

Procedimiento para preparar 17 beta-acetoxi-8,13-expoxi-ialfa.6beta,9alfa-trihidroxilabol-14-en-11-ona,sus compuestos analogos y derivados.

Info

Publication number
ES551203A0
ES551203A0 ES551203A ES551203A ES551203A0 ES 551203 A0 ES551203 A0 ES 551203A0 ES 551203 A ES551203 A ES 551203A ES 551203 A ES551203 A ES 551203A ES 551203 A0 ES551203 A0 ES 551203A0
Authority
ES
Spain
Prior art keywords
dsm
compound
formula
strain
see diagramm
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES551203A
Other languages
English (en)
Other versions
ES8705873A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES551203A0 publication Critical patent/ES551203A0/es
Publication of ES8705873A1 publication Critical patent/ES8705873A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/92Naphthopyrans; Hydrogenated naphthopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ES551203A 1985-01-26 1986-01-24 Procedimiento para preparar 17 beta-acetoxi-8,13-expoxi-ialfa.6beta,9alfa-trihidroxilabol-14-en-11-ona,sus compuestos analogos y derivados. Expired ES8705873A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853502685 DE3502685A1 (de) 1985-01-26 1985-01-26 Forskolin, seine analoge und derivate, verfahren zu deren herstellung mittels mikrobieller umwandlungen und die anwendung dieser verbindungen als arzneimittel

Publications (2)

Publication Number Publication Date
ES551203A0 true ES551203A0 (es) 1987-05-16
ES8705873A1 ES8705873A1 (es) 1987-05-16

Family

ID=6260903

Family Applications (1)

Application Number Title Priority Date Filing Date
ES551203A Expired ES8705873A1 (es) 1985-01-26 1986-01-24 Procedimiento para preparar 17 beta-acetoxi-8,13-expoxi-ialfa.6beta,9alfa-trihidroxilabol-14-en-11-ona,sus compuestos analogos y derivados.

Country Status (8)

Country Link
EP (1) EP0189801B1 (es)
JP (1) JPS61180782A (es)
AT (1) ATE40362T1 (es)
DE (2) DE3502685A1 (es)
DK (1) DK37586A (es)
ES (1) ES8705873A1 (es)
GR (1) GR860206B (es)
PT (1) PT81900B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963537A (en) * 1985-03-01 1990-10-16 Hoechst-Roussel Pharmaceuticals Inc. Labdane compounds, pharmaceutical compositions and use
IN163242B (es) 1985-05-03 1988-08-27 Hoechst India
US5247097A (en) * 1986-08-28 1993-09-21 Hoechst-Roussel Pharmaceuticals Incorporated Oxolabdanes
US4740522A (en) * 1986-08-28 1988-04-26 Hoechst-Roussel Pharmaceuticals Inc. Oxolabdanes useful as pharmaceuticals for reducing intraocular pressure
US4920146A (en) * 1986-12-29 1990-04-24 Hoechst Roussel Pharmaceuticals Inc. Carbamoyloxylabdane compounds useful in reducing intraocular pressure
US5646175A (en) * 1987-12-28 1997-07-08 Hoechst Marion Roussel, Inc. Carbamoyloxylabdane compounds
IN166900B (es) * 1987-06-03 1990-08-04 Hoechst India
AT389114B (de) * 1987-10-08 1989-10-25 Hoechst Ag 7-acyloxy-6-aminoacyloxypolyoxylabdane und verfahren zu ihrer herstellung
US4883793A (en) * 1988-05-09 1989-11-28 Hoechst-Roussel Pharmaceuticals Inc. Hydrazinocarbonyloxylabdanes for treating cardiac failure
US5177207A (en) * 1989-01-11 1993-01-05 Hoechst-Roussel Pharmaceuticals, Inc. 7-aryl and heteroaryl ethers of desacetylforskolin
US4999351A (en) * 1989-01-11 1991-03-12 Hoechst-Roussel Pharmaceuticals, Inc. 7-aryl and heteroaryl ethers of desacetylforskolin
US5145855A (en) * 1989-07-06 1992-09-08 Hoechst Roussel Pharmaceuticals, Inc. 6- and 7-deoxyforskolin and derivatives thereof
US5093336A (en) * 1989-07-06 1992-03-03 Hoechat-Roussel Pharmaceuticals, Inc. 6- and 7-deoxyforskolin and derivatives thereof
US5629345A (en) * 1993-07-23 1997-05-13 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
US5965620A (en) * 1993-07-23 1999-10-12 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
JP5933419B2 (ja) * 2012-11-26 2016-06-08 株式会社シャローム ジテルペン化合物、美白剤およびジテルペン化合物の製造方法
JP5933420B2 (ja) * 2012-11-26 2016-06-08 株式会社シャローム 新規化合物、美白剤および前記化合物の製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557784C2 (de) * 1975-12-22 1986-04-17 Hoechst Ag, 6230 Frankfurt Forskolin, Verfahren zu dessen Gewinnung und diese Verbindung enthaltende pharmazeutische Präparate
DE2654796A1 (de) * 1976-12-03 1978-06-08 Hoechst Ag Polyoxygenierte labdan-derivate
US4517200A (en) * 1982-12-27 1985-05-14 Schering-Plough Corporation Method for treating allergic reactions with forskolin
DE3314999A1 (de) * 1983-04-26 1985-03-14 Behringwerke Ag, 3550 Marburg Verwendung des diterpen-derivates forskolin zur immunstimulation
US4476140A (en) * 1983-05-16 1984-10-09 Yale University Composition and method for treatment of glaucoma
WO1985002616A1 (en) * 1983-12-14 1985-06-20 Brown University Research Foundation Treatment of metastasis

Also Published As

Publication number Publication date
GR860206B (en) 1986-05-21
DK37586D0 (da) 1986-01-24
DE3502685A1 (de) 1986-09-04
PT81900B (pt) 1988-07-01
JPS61180782A (ja) 1986-08-13
DE3661915D1 (en) 1989-03-02
DK37586A (da) 1986-07-27
EP0189801A1 (de) 1986-08-06
ATE40362T1 (de) 1989-02-15
ES8705873A1 (es) 1987-05-16
EP0189801B1 (de) 1989-01-25
PT81900A (de) 1986-02-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401