ES556748A0 - Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxolicas. - Google Patents
Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxolicas.Info
- Publication number
- ES556748A0 ES556748A0 ES556748A ES556748A ES556748A0 ES 556748 A0 ES556748 A0 ES 556748A0 ES 556748 A ES556748 A ES 556748A ES 556748 A ES556748 A ES 556748A ES 556748 A0 ES556748 A0 ES 556748A0
- Authority
- ES
- Spain
- Prior art keywords
- hydroxyphenoxialkyleneheterociclyl
- carboxolic
- acids
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/58—Two sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/16—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/70—Sulfur atoms
- C07D277/74—Sulfur atoms substituted by carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C07D285/135—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23899184 | 1984-11-12 | ||
| JP21932785 | 1985-10-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES556748A0 true ES556748A0 (es) | 1987-12-16 |
| ES8801232A1 ES8801232A1 (es) | 1987-12-16 |
Family
ID=26523058
Family Applications (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES548772A Expired ES8707947A1 (es) | 1984-11-12 | 1985-11-11 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
| ES556747A Expired ES8801187A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
| ES556748A Expired ES8801232A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxolicas. |
| ES556746A Expired ES8801231A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
| ES556753A Expired ES8801189A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
| ES556752A Expired ES8801188A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
| ES556751A Expired ES8801235A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
| ES556749A Expired ES8801233A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
| ES556750A Expired ES8801234A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES548772A Expired ES8707947A1 (es) | 1984-11-12 | 1985-11-11 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
| ES556747A Expired ES8801187A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
Family Applications After (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES556746A Expired ES8801231A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
| ES556753A Expired ES8801189A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
| ES556752A Expired ES8801188A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
| ES556751A Expired ES8801235A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
| ES556749A Expired ES8801233A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
| ES556750A Expired ES8801234A1 (es) | 1984-11-12 | 1986-06-25 | Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos. |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US4855310A (es) |
| EP (1) | EP0181779B1 (es) |
| KR (1) | KR900004804B1 (es) |
| AT (1) | ATE102930T1 (es) |
| CA (1) | CA1269982A (es) |
| DE (1) | DE3587777T2 (es) |
| ES (9) | ES8707947A1 (es) |
| PH (1) | PH22520A (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61186368A (ja) * | 1985-02-14 | 1986-08-20 | Kyorin Pharmaceut Co Ltd | 新規な抗アレルギ−薬およびその製造方法 |
| US5180730A (en) * | 1985-07-22 | 1993-01-19 | Yamanouchi Pharmaceutical Co., Ltd. | Heterocyclic compounds |
| US4803211A (en) * | 1985-07-22 | 1989-02-07 | Yamanouchi Pharmaceutical Co., Ltd. | Thiadizazole compounds as antagonists of SRS-A |
| US4942245A (en) * | 1987-04-20 | 1990-07-17 | Kyorin Pharmaceutical Co., Ltd. | Benzimidazole Derivatives |
| JPH0667836B2 (ja) * | 1989-03-01 | 1994-08-31 | 東洋紡績株式会社 | アミド系化合物からなる抗アレルギー剤 |
| US5102897A (en) * | 1990-03-27 | 1992-04-07 | Warner-Lambert Company | 3,5-ditertiarybutyl-4-hydroxyphenyl, 1,3,4-thiadiazoles and oxadiazoles linked by carbon, oxygen, and sulfur residues |
| DE4035599A1 (de) * | 1990-11-06 | 1992-05-07 | Dresden Arzneimittel | Neue 5-(phenoxyalkanoylamino)-uracile, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| JP2002504892A (ja) * | 1997-04-11 | 2002-02-12 | イーライ・リリー・アンド・カンパニー | ペプチド様アミノチオエーテル酸の組み合わせライブラリー |
| CN1231212C (zh) | 1999-01-22 | 2005-12-14 | 依兰制药公司 | 抑制vla－4介导的白细胞粘着的多环化合物 |
| IL143928A0 (en) * | 1999-01-22 | 2002-04-21 | Elan Pharm Inc | Fused ring heteroaryl and heterocyclic compounds which inhibit leukocyte adhesion mediated by vla-4 |
| PL350050A1 (en) | 1999-01-22 | 2002-10-21 | Elan Pharm Inc | Acyl derivatives which treat vla-4 related disorders |
| US6436904B1 (en) | 1999-01-25 | 2002-08-20 | Elan Pharmaceuticals, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| ATE264298T1 (de) | 1999-03-01 | 2004-04-15 | Elan Pharm Inc | Alpha-aminoessigsäure derivate als alpha 4 beta 7-rezeptor antagonisten |
| US6552073B1 (en) * | 2002-03-01 | 2003-04-22 | Exonhit Therapeutics Sa | Compounds and methods of treating cell proliferative diseases |
| TW200307671A (en) * | 2002-05-24 | 2003-12-16 | Elan Pharm Inc | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins |
| TWI281470B (en) * | 2002-05-24 | 2007-05-21 | Elan Pharm Inc | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins |
| EP1521577A1 (en) * | 2002-06-13 | 2005-04-13 | QLT, Inc. | Methods of using isothiazole derivatives to treat cancer or inflammation |
| ATE493405T1 (de) * | 2005-09-29 | 2011-01-15 | Elan Pharm Inc | Pyrimidinylamidverbindungen, die die durch vla-4 vermittelte leukozytenadhäsion inhibieren |
| CA2624524C (en) * | 2005-09-29 | 2014-07-08 | Elan Pharmaceuticals, Inc. | Carbamate compounds which inhibit leukocyte adhesion mediated by vla-4 |
| WO2007101165A1 (en) * | 2006-02-27 | 2007-09-07 | Elan Pharmaceuticals, Inc. | Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by vla-4 |
| AU2010241742A1 (en) * | 2009-04-27 | 2011-11-17 | Elan Pharmaceuticals, Inc. | Pyridinone antagonists of alpha-4 integrins |
| CA2782797C (en) | 2009-10-02 | 2018-08-07 | Avexxin As | Anti inflammatory 2-oxothiazoles and 2 -oxooxazoles |
| CN105102438B (zh) | 2013-01-29 | 2019-04-30 | 埃维克辛公司 | 抗炎症和抗肿瘤的2-氧代噻唑类和2-氧代噻吩类化合物 |
| GB201413695D0 (en) | 2014-08-01 | 2014-09-17 | Avexxin As | Compound |
| GB201604318D0 (en) | 2016-03-14 | 2016-04-27 | Avexxin As | Combination therapy |
| CA3150299A1 (en) * | 2019-09-17 | 2021-03-25 | Paul E. Adams | 2,5-DIMERCAPTO-1,3,4-THIADIAZOLE DERIVATIVES ("DMTD") |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1546937A (en) * | 1976-07-29 | 1979-05-31 | Beecham Group Ltd | 2,4-diaminopyrimidine derivatives |
| JPS591268B2 (ja) * | 1978-10-18 | 1984-01-11 | 興和株式会社 | チアジアゾ−ル誘導体 |
| US4411905A (en) * | 1979-09-04 | 1983-10-25 | Richardson-Merrell Inc. | Antisecretory 1,2,4-triazole-3-thiols |
| AU554388B2 (en) * | 1981-06-15 | 1986-08-21 | American Home Products Corporation | Alpha-phenyl-2-(aza)benzothiazolylthioglycolic acid derivatives |
| EP0084673B1 (de) * | 1982-01-22 | 1986-04-02 | BASF Aktiengesellschaft | Aminothiadiazole, Verfahren zu ihrer Herstellung und ihre Verwendung zur Bekämpfung unerwünschten Pflanzenwuchses |
| US4517188A (en) * | 1983-05-09 | 1985-05-14 | Mead Johnson & Company | 1-Pyrimidinyloxy-3-hetaryl-alkylamino-2-propanols |
| US4672066A (en) * | 1985-04-22 | 1987-06-09 | Hoffmann-La Roche Inc. | Derivatives of 4-acetyl-3-hydroxy-2-alkyl-phenoxycarboxylic acids |
| US4803211A (en) * | 1985-07-22 | 1989-02-07 | Yamanouchi Pharmaceutical Co., Ltd. | Thiadizazole compounds as antagonists of SRS-A |
-
1985
- 1985-11-07 PH PH33025A patent/PH22520A/en unknown
- 1985-11-11 ES ES548772A patent/ES8707947A1/es not_active Expired
- 1985-11-11 KR KR1019850008402A patent/KR900004804B1/ko not_active Expired
- 1985-11-12 CA CA000495080A patent/CA1269982A/en not_active Expired - Fee Related
- 1985-11-12 EP EP85308227A patent/EP0181779B1/en not_active Expired - Lifetime
- 1985-11-12 DE DE3587777T patent/DE3587777T2/de not_active Expired - Fee Related
- 1985-11-12 AT AT85308227T patent/ATE102930T1/de not_active IP Right Cessation
-
1986
- 1986-06-25 ES ES556747A patent/ES8801187A1/es not_active Expired
- 1986-06-25 ES ES556748A patent/ES8801232A1/es not_active Expired
- 1986-06-25 ES ES556746A patent/ES8801231A1/es not_active Expired
- 1986-06-25 ES ES556753A patent/ES8801189A1/es not_active Expired
- 1986-06-25 ES ES556752A patent/ES8801188A1/es not_active Expired
- 1986-06-25 ES ES556751A patent/ES8801235A1/es not_active Expired
- 1986-06-25 ES ES556749A patent/ES8801233A1/es not_active Expired
- 1986-06-25 ES ES556750A patent/ES8801234A1/es not_active Expired
-
1988
- 1988-03-25 US US07/173,734 patent/US4855310A/en not_active Expired - Fee Related
-
1989
- 1989-06-07 US US07/362,959 patent/US4908368A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES8801234A1 (es) | 1987-12-16 |
| ES556750A0 (es) | 1987-12-16 |
| ES8801187A1 (es) | 1987-12-16 |
| PH22520A (en) | 1988-10-17 |
| ES556747A0 (es) | 1987-12-16 |
| DE3587777D1 (de) | 1994-04-21 |
| EP0181779B1 (en) | 1994-03-16 |
| ES8707947A1 (es) | 1987-09-01 |
| ES556753A0 (es) | 1987-12-16 |
| ES556751A0 (es) | 1987-12-16 |
| ES556749A0 (es) | 1987-12-16 |
| ES556746A0 (es) | 1987-12-16 |
| ATE102930T1 (de) | 1994-04-15 |
| US4908368A (en) | 1990-03-13 |
| DE3587777T2 (de) | 1994-06-23 |
| ES8801189A1 (es) | 1987-12-16 |
| CA1269982A (en) | 1990-06-05 |
| US4855310A (en) | 1989-08-08 |
| ES556752A0 (es) | 1987-12-16 |
| ES8801188A1 (es) | 1987-12-16 |
| KR900004804B1 (ko) | 1990-07-06 |
| KR860004041A (ko) | 1986-06-16 |
| ES548772A0 (es) | 1987-09-01 |
| EP0181779A1 (en) | 1986-05-21 |
| ES8801231A1 (es) | 1987-12-16 |
| ES8801232A1 (es) | 1987-12-16 |
| ES8801235A1 (es) | 1987-12-16 |
| ES8801233A1 (es) | 1987-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19971001 |