ES8201316A1 - Procedimiento de preparar agentes de utilidad clinica a par-tir de substancias solubles en lipoides - Google Patents

Procedimiento de preparar agentes de utilidad clinica a par-tir de substancias solubles en lipoides

Info

Publication number
ES8201316A1
ES8201316A1 ES80498048A ES498048A ES8201316A1 ES 8201316 A1 ES8201316 A1 ES 8201316A1 ES 80498048 A ES80498048 A ES 80498048A ES 498048 A ES498048 A ES 498048A ES 8201316 A1 ES8201316 A1 ES 8201316A1
Authority
ES
Spain
Prior art keywords
biologically active
lipoid
preparing
active particles
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES80498048A
Other languages
English (en)
Other versions
ES498048A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HUMAN OLTOANYAGTERMELO
Original Assignee
HUMAN OLTOANYAGTERMELO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HUMAN OLTOANYAGTERMELO filed Critical HUMAN OLTOANYAGTERMELO
Publication of ES8201316A1 publication Critical patent/ES8201316A1/es
Publication of ES498048A0 publication Critical patent/ES498048A0/es
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/586—Liposomes, microcapsules or cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)

Abstract

PROCEDIMIENTO DE PREPARAR AGENTES DE UTILIDAD CLINICA A PARTIR DE SUSTANCIAS SOLUBLES EN LIPOIDES. SE MEZCLA UNA SUSTANCI FORMADORA DE PARTICULAS DE LIPOIDES QUE CONTIENE UN AGENTE DE ACTIVIDAD SUPERFICIAL DISUELTO EN ALCOHOL, O CUALQUIER OTRO DISOLVENTE ORGANICO, CON UNA DISOLUCION DE UNA SUSTANCIA BIOLOGICAMENTE ACTIVA EN AGUA O UNA DISOLUCION CON UN PH DE 2 A 10, EN UNA RELACION DE VOLUMEN DE 1: 1000 A 9: 1, AGITANDO LA MEZCLA DE REACCION DURANTE UN MINUTO, AL MENOS, Y DEJANDOLO REPOSAR DURANTE SIETE DIAS, PARA LUEGO SEPARAR LAS PARTICULAS PRECIPITADAS. TAMBIEN SE PUEDE MEZCLAR CON UNA SOLUCION ELECTROLITICA ACUOSA, SEPARANDO LAS PARTICULAS PRECIPITADAS Y SUSPENDERLAS EN AGUA O EN UNA DISOLUCION ELECTROLITICA ACUOSA CON AGITACION O SIN ELLA. SE UTILIZA PARA PREPARAR SISTEMAS PARA EXAMENES DE INMUNODIAGNOSIS <IN VITRO>, COMO DIAGNOSTICO DE UNA DETERMINACION CUANTITATIVA DE ARTRITIS REUMATOIDE.
ES498048A 1979-12-27 1980-12-22 Procedimiento de preparar agentes de utilidad clinica a par-tir de substancias solubles en lipoides Granted ES498048A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79HU299A HU184141B (en) 1979-12-27 1979-12-27 Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof

Publications (2)

Publication Number Publication Date
ES8201316A1 true ES8201316A1 (es) 1981-12-16
ES498048A0 ES498048A0 (es) 1981-12-16

Family

ID=10997378

Family Applications (1)

Application Number Title Priority Date Filing Date
ES498048A Granted ES498048A0 (es) 1979-12-27 1980-12-22 Procedimiento de preparar agentes de utilidad clinica a par-tir de substancias solubles en lipoides

Country Status (21)

Country Link
US (1) US4396630A (es)
JP (1) JPS57112334A (es)
BE (1) BE886884A (es)
CA (1) CA1165237A (es)
CH (1) CH655246A5 (es)
CS (1) CS241478B2 (es)
DD (1) DD158738A5 (es)
DE (1) DE3048815A1 (es)
DK (1) DK160288C (es)
ES (1) ES498048A0 (es)
FR (1) FR2472386B1 (es)
GB (1) GB2066203B (es)
HU (1) HU184141B (es)
IT (1) IT1150073B (es)
NL (1) NL8007041A (es)
PL (1) PL228755A1 (es)
PT (1) PT72261B (es)
RO (1) RO81371A (es)
SE (1) SE453537B (es)
SU (1) SU1487802A3 (es)
YU (1) YU44413B (es)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4598051A (en) * 1980-03-12 1986-07-01 The Regents Of The University Of California Liposome conjugates and diagnostic methods therewith
US4806466A (en) * 1981-10-29 1989-02-21 The Regents Of The University Of California Cell agglutination reagent comprising conjugates of antibody covalently bound to liposomes
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
DD247570A3 (de) * 1983-01-14 1987-07-15 Univ Berlin Humboldt Vesikulaeres trenn-, fuell- und traegermaterial
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
US5059591B1 (en) * 1983-05-26 2000-04-25 Liposome Co Inc Drug preparations of reduced toxicity
US4708861A (en) * 1984-02-15 1987-11-24 The Liposome Company, Inc. Liposome-gel compositions
US5916588A (en) * 1984-04-12 1999-06-29 The Liposome Company, Inc. Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
US6090406A (en) * 1984-04-12 2000-07-18 The Liposome Company, Inc. Potentiation of immune responses with liposomal adjuvants
GB2160312B (en) * 1984-04-13 1987-09-16 South African Inventions Adjuvant for immunisation
PT78628B (en) * 1984-05-02 1986-06-18 Liposome Co Inc Pharmaceutical composition with reduced toxicity
US4619904A (en) * 1984-10-29 1986-10-28 General Electric Company Agglutinating immunoassay using protein-coated liquid droplets
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
JP2519029B2 (ja) * 1985-10-31 1996-07-31 ケ−・ブイ・ファ−マシュ−ティカル・カンパニ− 腟内送達用製剤
US5266329A (en) * 1985-10-31 1993-11-30 Kv Pharmaceutical Company Vaginal delivery system
US4790987A (en) * 1985-11-15 1988-12-13 Research Corporation Viral glycoprotein subunit vaccine
CA1338736C (fr) * 1986-12-05 1996-11-26 Roger Baurain Microcristaux comportant une substance active presentant une affinite pour les phospholipides, et au moins un phospholipide, procede de preparation
US5688519A (en) * 1987-04-06 1997-11-18 Leonard; Robert J. Flash-flow fused medicinal implants
US4748024A (en) * 1987-04-06 1988-05-31 Endocon, Inc. Flash flow fused medicinal implants
WO1990001947A1 (en) * 1988-08-25 1990-03-08 The Liposome Company, Inc. Affinity associated vaccine
EP0374296B1 (en) * 1988-12-22 1995-02-01 Dade International Inc. Lipohaptens and use of carrier-bound lipohaptens in immunoassays
US5100662A (en) * 1989-08-23 1992-03-31 The Liposome Company, Inc. Steroidal liposomes exhibiting enhanced stability
JPH07113641B2 (ja) * 1989-11-17 1995-12-06 積水化学工業株式会社 梅毒診断試薬の製造方法
NL9000207A (es) * 1990-01-29 1991-08-16 Duphar Int Res
US5709879A (en) * 1990-06-29 1998-01-20 Chiron Corporation Vaccine compositions containing liposomes
WO1992000081A1 (en) * 1990-06-29 1992-01-09 Chiron Corporation Vaccine compositions containing liposomes
IE912535A1 (en) * 1990-07-27 1992-01-29 Res Dev Foundation Liposomes that Provide Thymic Dependent Help to Weak Vaccine¹Antigens
WO1992004887A1 (fr) * 1990-09-25 1992-04-02 Kyowa Hakko Kogyo Co., Ltd. Production de lymphocites t cytotoxiques
US6048531A (en) * 1991-04-15 2000-04-11 Albany Medical College Immunogenic composites capable of stimulating production of anti-peptide antibodies, pharmaceutical compositions employing these composites and methods of selectively inducing production of anti-peptide antibodies
US5336507A (en) * 1992-12-11 1994-08-09 Sterling Winthrop Inc. Use of charged phospholipids to reduce nanoparticle aggregation
GB9320668D0 (en) 1993-10-07 1993-11-24 Secr Defence Liposomes containing particulare materials
AUPM500494A0 (en) * 1994-04-12 1994-05-05 Minister For Agriculture & Rural Affairs For The State Of New South Wales, The Composition for use in increasing mucosal immunity
HUP0302352A3 (en) * 2000-11-09 2007-03-28 Neopharm Sn-38 lipid complexes and methods of use
WO2003030864A1 (en) * 2001-05-29 2003-04-17 Neopharm, Inc. Liposomal formulation of irinotecan
AU2003230600B2 (en) * 2002-03-05 2009-06-04 Transave, Inc. An inhalation system for prevention and treatment of intracellular infections
AU2003296897A1 (en) * 2002-08-20 2004-05-04 Neopharm, Inc. Pharmaceutical formulations of camptothecine derivatives
US20060030578A1 (en) * 2002-08-20 2006-02-09 Neopharm, Inc. Pharmaceutically active lipid based formulation of irinotecan
AU2003304204B2 (en) * 2002-10-29 2009-12-24 Insmed Incorporated Sustained release of antiinfectives
US7879351B2 (en) * 2002-10-29 2011-02-01 Transave, Inc. High delivery rates for lipid based drug formulations, and methods of treatment thereof
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
KR100651728B1 (ko) * 2004-11-10 2006-12-06 한국전자통신연구원 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법
WO2006090816A1 (ja) * 2005-02-25 2006-08-31 Mie University リポソームワクチンの作製法
ES2798263T3 (es) 2005-12-08 2020-12-10 Insmed Inc Composiciones a base de lípidos de antiinfecciosos para tratar infecciones pulmonares
WO2008137717A1 (en) 2007-05-04 2008-11-13 Transave, Inc. Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
PL2852391T3 (pl) 2012-05-21 2022-04-11 Insmed Incorporated Układy do leczenia infekcji płuc
CA2891487A1 (en) 2012-11-29 2014-06-05 Insmed Incorporated Stabilized vancomycin formulations
MX384843B (es) 2014-05-15 2025-03-14 Insmed Inc Métodos para tratar infecciones pulmonares micobacterianas no tuberculosas.
EP3773505B1 (en) 2018-03-30 2026-04-29 Insmed Incorporated Methods for continuous manufacture of liposomal drug products
EP3787602A4 (en) 2018-05-02 2022-03-23 Insmed Incorporated PROCESS FOR THE MANUFACTURE OF LIPOSOMAL DRUG FORMULATIONS

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3265629A (en) * 1958-12-22 1966-08-09 Ncr Co Coating by phase separation
DE2249552A1 (de) * 1971-10-12 1973-05-30 Inchema S A Verfahren zur inkapsulation von insbesondere wasserloeslichen verbindungen
GB1502774A (en) * 1974-06-25 1978-03-01 Nat Res Dev Immunological preparations
JPS5126213A (ja) * 1974-08-21 1976-03-04 Tanabe Seiyaku Co Johoseibiryushiseizaino seiho
GB1564500A (en) * 1975-09-29 1980-04-10 Wellcome Found Biological preparations
GB1523965A (en) * 1976-03-19 1978-09-06 Ici Ltd Pharmaceutical compositions containing steroids
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
IT1110989B (it) * 1979-01-19 1986-01-13 Erba Farmitalia Forme farmaceutiche costitutite da liposomi e procedimenti relativi
FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
JPS55118415A (en) * 1979-02-28 1980-09-11 Pii Papahadojiyopo Dometoriosu Method of encapsulating biologically active substance in lipoid cell

Also Published As

Publication number Publication date
DK160288C (da) 1991-08-05
JPH0314814B2 (es) 1991-02-27
IT8026950A0 (it) 1980-12-24
US4396630A (en) 1983-08-02
RO81371B (ro) 1983-11-02
BE886884A (fr) 1981-06-29
GB2066203A (en) 1981-07-08
FR2472386B1 (es) 1985-08-23
DK160288B (da) 1991-02-25
RO81371A (ro) 1984-04-02
PL228755A1 (es) 1982-02-15
DK552280A (da) 1981-06-28
CS241478B2 (en) 1986-03-13
ES498048A0 (es) 1981-12-16
CA1165237A (en) 1984-04-10
IT1150073B (it) 1986-12-10
FR2472386A1 (es) 1981-07-03
PT72261A (en) 1981-01-01
SE453537B (sv) 1988-02-08
SU1487802A3 (ru) 1989-06-15
DE3048815A1 (de) 1981-09-10
YU44413B (en) 1990-08-31
GB2066203B (en) 1984-01-11
CS924680A2 (en) 1985-07-16
YU329080A (en) 1984-04-30
JPS57112334A (en) 1982-07-13
HU184141B (en) 1984-07-30
NL8007041A (nl) 1981-07-16
DD158738A5 (de) 1983-02-02
CH655246A5 (de) 1986-04-15
SE8009068L (sv) 1981-06-28
PT72261B (en) 1981-11-05

Similar Documents

Publication Publication Date Title
SE8009068L (sv) Partiklar av lipoidlosliga substanser, blandningar innefattande sadana partiklar och pa dessa adsorberade biologiskt aktiva substanser liksom even sett for framstellning av sadana blandningar
AU587525B2 (en) Indolizine derivatives, process for preparing them and the compositions containing them
AU646112B2 (en) N,O-sulphated heparosans, process for preparing them and pharmaceutical compositions containing them
ZA921875B (en) New esters of bi- and tricyclic amino alcohols, their preparation and their use in pharmaceutical compositions
EP0326618A4 (en) MEDICINAL COMPOSITION CONTAINING ALBUMIN AS SUPPORT AND PREPARATION METHOD.
PT83509A (en) Process for the preparation of pharmaceutical compositions with controlled release of metoprolol
PH21386A (en) Platinum-diamine complexes, their pharmaceutical compositions and process for the preparation thereof
DE3060777D1 (en) Drug composition based on plants and process for its preparation
HUT37424A (en) Process for preparing new 5-pyridyl-1,3-thiazoie derivatives and pharmaceutical compositions containing thereof as active substances
AU5642294A (en) Bacteriocidal gas composition and process for preparing the same
HUT36991A (en) Herbicide compositions containing 1-aryl-4-substituted-1,4-dihydro-5h-tetrazol-5-one /or-thione/ derivatives and process for preparing the active substances
HUT42292A (en) Insecticidal compositions comprising fluorbenzyl esters as active substance and process for preparing the active substances
EP0175667A3 (en) Macrophage-activating composition and a process for its manufacture
CS78485A3 (en) Biologically usable preparation containing as an active component methylhydroxyprogesterone acetate and process for preparing thereof
HUT36345A (en) Herbicide compositions containing cyano-pyrazole derivatives as active substances and process for preparing the active substances
DE3361610D1 (en) Enzyme derivatives, process for preparing them and pharmaceutical compositions containing them
DE3167664D1 (en) Pyrazoloindazole derivatives, process for preparing the same, and pharmaceutical composition containing the same
AU552567B2 (en) Oligopeptides with specific inhibiting properties of collageninduced aggregation, process for preparing the same and pharmaceutical compositions containing them
DE3169602D1 (en) 2-pyridinecarboxamide derivative, process for preparing same and pharmaceutical composition, useful as an anti-allergic agent
HUT37857A (en) Insectide compositions containing cyclodextrin inclusion complex as active substance and process for preparing the active substances
DE3366324D1 (en) Peptides, process for preparing the same and psychodepressant compositions containing the same
AU540216B2 (en) Nicotinamide derivative, process for preparing the same and pharmaceutical composition containing the same
DE3479656D1 (en) Rhodanine derivative, process for preparing the same and pharmaceutical composition containing the same
IL61099A (en) 9-deoxy-6,9alpha-imino-delta6,8-pgi analogues,process for their preparation and pharmaceutical compositions containing them
DE3160797D1 (en) 11-alpha-amino androstanes, pharmaceutical compositions containing them and processes for their preparation