ES8302462A1 - "un metodo para obtener una preparacion de insulina". - Google Patents

"un metodo para obtener una preparacion de insulina".

Info

Publication number
ES8302462A1
ES8302462A1 ES82510245A ES510245A ES8302462A1 ES 8302462 A1 ES8302462 A1 ES 8302462A1 ES 82510245 A ES82510245 A ES 82510245A ES 510245 A ES510245 A ES 510245A ES 8302462 A1 ES8302462 A1 ES 8302462A1
Authority
ES
Spain
Prior art keywords
magnesium
production
calcium
insulin
insulin preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES82510245A
Other languages
English (en)
Other versions
ES510245A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Industri AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri AS filed Critical Novo Industri AS
Publication of ES8302462A1 publication Critical patent/ES8302462A1/es
Publication of ES510245A0 publication Critical patent/ES510245A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Dental Preparations (AREA)

Abstract

METODO PARA OBTENER UNA PREPARACION DE INSULINA, ADECUADA PARA UTILIZARLA EN SISTEMAS DE SUMINISTRO DE INSULINA. SE DISUELVE LA INSULINA, JUNTO CON CALCIO O MAGNESIO EN FORMA ESENCIALMENTE IONIZABLE, EN UNA CONCENTRACION SUFICIENTE PARA COMUNICAR A DICHA SOLUCION LA ESTABILIDAD FISICA NECESARIA, PERO INSUFICIENTE PARA INDUCIR LA PRECIPITACION DE INSULINA EN ELLA, EN LAS CONDICIONES NORMALES. DESPUES SE AÑADE UN AGENTE DE CONSERVACION Y, OPCIONALMENTE, UN AGENTE NO IONIZANTE REGULADOR DE LA PRESION OSMOTICA Y/O UN AGENTE TAMPONADOR DEL PH QUE NO FORMA COMPLEJO NI COMPUESTOS LIGERAMENTE SOLUBLES CON LOS IONES CALCIO O MAGNESIO.
ES82510245A 1981-03-10 1982-03-09 "un metodo para obtener una preparacion de insulina". Granted ES510245A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8107423 1981-03-10
DK414381 1981-09-18

Publications (2)

Publication Number Publication Date
ES8302462A1 true ES8302462A1 (es) 1983-01-16
ES510245A0 ES510245A0 (es) 1983-01-16

Family

ID=26067363

Family Applications (1)

Application Number Title Priority Date Filing Date
ES82510245A Granted ES510245A0 (es) 1981-03-10 1982-03-09 "un metodo para obtener una preparacion de insulina".

Country Status (14)

Country Link
US (1) US4472385A (es)
EP (1) EP0060141B1 (es)
AT (1) ATE23269T1 (es)
AU (1) AU550068B2 (es)
CA (1) CA1170990A (es)
CH (1) CH652031A5 (es)
DE (1) DE3274064D1 (es)
ES (1) ES510245A0 (es)
FI (1) FI78838C (es)
FR (1) FR2501507B1 (es)
GB (1) GB2094145B (es)
IE (1) IE52904B1 (es)
IT (1) IT1150639B (es)
NO (1) NO157843C (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985002544A1 (en) * 1983-12-16 1985-06-20 Thomas Takemi Aoki Insulin delivery algorithm
PH23446A (en) * 1986-10-20 1989-08-07 Novo Industri As Peptide preparations
IE62879B1 (en) * 1987-02-25 1995-03-08 Novo Nordisk As Novel insulin derivatives
US4789660A (en) * 1987-09-10 1988-12-06 American Home Products Corporation Insulin administration using methyl and propyl paraben
BR9709845B1 (pt) † 1996-06-20 2008-11-18 preparaÇço aquosa de insulina, formulaÇço farmacÊutica parenteral, e, processso para aumentar a estabilidade quÍmica de uma preparaÇço de insulina.
AR012894A1 (es) * 1997-06-13 2000-11-22 Lilly Co Eli Formulacion de insulina en solucion estable, su uso para preparar un medicamento y proceso para la preparacion de la misma.
WO1999034821A1 (en) * 1998-01-09 1999-07-15 Novo Nordisk A/S Stabilised insulin compositions
US20020156434A1 (en) * 1998-03-13 2002-10-24 Minimed Inc. Stabilizing catheter for protein drug delivery
JP5599543B2 (ja) 2002-05-07 2014-10-01 ノヴォ ノルディスク アー／エス 単量体インスリン及びアシル化インスリンを含む可溶性製剤
US20030226223A1 (en) 2002-06-11 2003-12-11 The Procter & Gamble Co. High efficiency electric toothbrush
US7322066B2 (en) 2003-07-16 2008-01-29 Church & Dwight Co., Inc. Electric toothbrushes having movable, intermittently movable, and fixed bristles
US20050053895A1 (en) 2003-09-09 2005-03-10 The Procter & Gamble Company Attention: Chief Patent Counsel Illuminated electric toothbrushes emitting high luminous intensity toothbrush
US20050050659A1 (en) 2003-09-09 2005-03-10 The Procter & Gamble Company Electric toothbrush comprising an electrically powered element
FR2896164B1 (fr) * 2006-01-18 2008-07-04 Flamel Technologies Sa Formulation colloidale d'insuline longue action et sa preparation
FR2943538B1 (fr) * 2009-03-27 2011-05-20 Adocia Formulation a action rapide d'insuline recombinante humaine
US9018190B2 (en) 2009-03-27 2015-04-28 Adocia Functionalized oligosaccharides
US20130231281A1 (en) 2011-11-02 2013-09-05 Adocia Rapid acting insulin formulation comprising an oligosaccharide
CN104902922B (zh) 2012-11-13 2017-12-12 阿道恰公司 包含经取代阴离子化合物的速效胰岛素制剂
WO2015120457A1 (en) * 2014-02-10 2015-08-13 Biodel Inc. Stabilized ultra-rapid-acting insulin formulations
US9795678B2 (en) 2014-05-14 2017-10-24 Adocia Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound
FR3020947B1 (fr) 2014-05-14 2018-08-31 Adocia Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations
FR3043557B1 (fr) 2015-11-16 2019-05-31 Adocia Composition a action rapide d'insuline comprenant un citrate substitue

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR892194A (fr) * 1938-06-29 1944-03-30 Ig Farbenindustrie Ag Procédé de fabrication de préparations à base d'insuline
US2474729A (en) * 1945-01-03 1949-06-28 Rhone Poulenc Sa Insulin preparations
US3102077A (en) * 1953-08-19 1963-08-27 Christensen Henry Marinus Preparation of insulin containing 2.75 to 8 percent zinc content
DK98342C (da) * 1959-06-16 1964-03-31 Henry Marinus Dr Christensen Fremgangsmåde til fremstilling af et insulinpræparat til peroral applikation.
US4196196A (en) * 1978-06-19 1980-04-01 Tiholiz Ivan C Divalen/monovalent bipolar cation therapy for enhancement of tissue perfusion and reperfusion in disease states

Also Published As

Publication number Publication date
EP0060141A3 (en) 1983-08-24
IT1150639B (it) 1986-12-17
CA1170990A (en) 1984-07-17
CH652031A5 (de) 1985-10-31
FR2501507A1 (es) 1982-09-17
AU8111482A (en) 1982-09-16
NO820742L (no) 1982-09-13
DE3274064D1 (en) 1986-12-11
NO157843B (no) 1988-02-22
NO157843C (no) 1988-06-01
US4472385A (en) 1984-09-18
FR2501507B1 (es) 1986-04-18
ATE23269T1 (de) 1986-11-15
EP0060141A2 (en) 1982-09-15
IE52904B1 (en) 1988-04-13
FI820808L (fi) 1982-09-11
AU550068B2 (en) 1986-02-27
IT8220038A0 (it) 1982-03-09
FI78838C (fi) 1989-10-10
GB2094145A (en) 1982-09-15
IE820536L (en) 1982-09-10
EP0060141B1 (en) 1986-11-05
ES510245A0 (es) 1983-01-16
FI78838B (fi) 1989-06-30
GB2094145B (en) 1984-12-05

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