IT8220038A0 - Preparazione di insulina stabilizzate e metodo per la loro produzione. - Google Patents

Preparazione di insulina stabilizzate e metodo per la loro produzione.

Info

Publication number: IT8220038A0
Authority: IT; Italy
Prior art keywords: preparation; production; stabilized insulin; insulin; stabilized
Prior art date: 1981-03-10

Application number

IT8220038A

Other languages

English (en)

Other versions

IT1150639B (it

Inventor

Jens Jorgen Veilgaard Brange

Svend Havelund

Original Assignee

Novo Industri As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-03-10

Filing date

1982-03-09

Publication date

1982-03-09

1982-03-09 Application filed by Novo Industri As filed Critical Novo Industri As

1982-03-09 Publication of IT8220038A0 publication Critical patent/IT8220038A0/it

1986-12-17 Application granted granted Critical

1986-12-17 Publication of IT1150639B publication Critical patent/IT1150639B/it

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
102000004877 Insulin Human genes 0.000 title 1
108090001061 Insulin Proteins 0.000 title 1
229940125396 insulin Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)
Dental Preparations (AREA)

IT8220038A 1981-03-10 1982-03-09 Preparazione di insulina stabilizzate e metodo per la loro produzione IT1150639B (it)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8107423		1981-03-10
DK414381		1981-09-18

Publications (2)

Publication Number	Publication Date
IT8220038A0 true IT8220038A0 (it)	1982-03-09
IT1150639B IT1150639B (it)	1986-12-17

Family

ID=26067363

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT8220038A IT1150639B (it)	1981-03-10	1982-03-09	Preparazione di insulina stabilizzate e metodo per la loro produzione

Country Status (14)

Country	Link
US (1)	US4472385A (it)
EP (1)	EP0060141B1 (it)
AT (1)	ATE23269T1 (it)
AU (1)	AU550068B2 (it)
CA (1)	CA1170990A (it)
CH (1)	CH652031A5 (it)
DE (1)	DE3274064D1 (it)
ES (1)	ES510245A0 (it)
FI (1)	FI78838C (it)
FR (1)	FR2501507B1 (it)
GB (1)	GB2094145B (it)
IE (1)	IE52904B1 (it)
IT (1)	IT1150639B (it)
NO (1)	NO157843C (it)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU588794B2 (en) *	1983-12-16	1989-09-28	Thomas Takemi Aoki	Insulin delivery method
PH23446A (en) *	1986-10-20	1989-08-07	Novo Industri As	Peptide preparations
DE3880346T2 (de) *	1987-02-25	1993-07-29	Novonordisk As	Insulinderivate.
US4789660A (en) *	1987-09-10	1988-12-06	American Home Products Corporation	Insulin administration using methyl and propyl paraben
DK0921812T4 (da) †	1996-06-20	2012-04-02	Novo Nordisk As	Insulinpræparater, som indeholder et halogenid
ZA984697B (en)	1997-06-13	1999-12-01	Lilly Co Eli	Stable insulin formulations.
DE69924232D1 (de) *	1998-01-09	2005-04-21	Novo Nordisk As	Stabilisierte insulin-zubereitungen
US20020156434A1 (en) *	1998-03-13	2002-10-24	Minimed Inc.	Stabilizing catheter for protein drug delivery
WO2003094956A1 (en)	2002-05-07	2003-11-20	Novo Nordisk A/S	Soluble formulations comprising monomeric insulin and acylated insulin
US20030226223A1 (en)	2002-06-11	2003-12-11	The Procter & Gamble Co.	High efficiency electric toothbrush
US7322066B2 (en)	2003-07-16	2008-01-29	Church & Dwight Co., Inc.	Electric toothbrushes having movable, intermittently movable, and fixed bristles
US20050050659A1 (en)	2003-09-09	2005-03-10	The Procter & Gamble Company	Electric toothbrush comprising an electrically powered element
US20050053895A1 (en)	2003-09-09	2005-03-10	The Procter & Gamble Company Attention: Chief Patent Counsel	Illuminated electric toothbrushes emitting high luminous intensity toothbrush
FR2896164B1 (fr) *	2006-01-18	2008-07-04	Flamel Technologies Sa	Formulation colloidale d'insuline longue action et sa preparation
US9018190B2 (en)	2009-03-27	2015-04-28	Adocia	Functionalized oligosaccharides
FR2943538B1 (fr) *	2009-03-27	2011-05-20	Adocia	Formulation a action rapide d'insuline recombinante humaine
US20130231281A1 (en)	2011-11-02	2013-09-05	Adocia	Rapid acting insulin formulation comprising an oligosaccharide
ES2670969T3 (es)	2012-11-13	2018-06-04	Adocia	Formulación de acción rápida de insulina que comprende un compuesto aniónico sustituido
US20150273022A1 (en) *	2014-02-10	2015-10-01	Biodel Inc.	Stabilized ultra-rapid-acting insulin formulations
FR3020947B1 (fr)	2014-05-14	2018-08-31	Adocia	Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations
US9795678B2 (en)	2014-05-14	2017-10-24	Adocia	Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound
FR3043557B1 (fr)	2015-11-16	2019-05-31	Adocia	Composition a action rapide d'insuline comprenant un citrate substitue

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR892194A (fr) *	1938-06-29	1944-03-30	Ig Farbenindustrie Ag	Procédé de fabrication de préparations à base d'insuline
US2474729A (en) *	1945-01-03	1949-06-28	Rhone Poulenc Sa	Insulin preparations
US3102077A (en) *	1953-08-19	1963-08-27	Christensen Henry Marinus	Preparation of insulin containing 2.75 to 8 percent zinc content
DK98342C (da) *	1959-06-16	1964-03-31	Henry Marinus Dr Christensen	Fremgangsmåde til fremstilling af et insulinpræparat til peroral applikation.
US4196196A (en) *	1978-06-19	1980-04-01	Tiholiz Ivan C	Divalen/monovalent bipolar cation therapy for enhancement of tissue perfusion and reperfusion in disease states

1982
- 1982-03-04 AU AU81114/82A patent/AU550068B2/en not_active Ceased
- 1982-03-09 FI FI820808A patent/FI78838C/fi not_active IP Right Cessation
- 1982-03-09 ES ES82510245A patent/ES510245A0/es active Granted
- 1982-03-09 IE IE536/82A patent/IE52904B1/en not_active IP Right Cessation
- 1982-03-09 CH CH1447/82A patent/CH652031A5/de not_active IP Right Cessation
- 1982-03-09 FR FR8203942A patent/FR2501507B1/fr not_active Expired
- 1982-03-09 NO NO820742A patent/NO157843C/no unknown
- 1982-03-09 EP EP82301207A patent/EP0060141B1/en not_active Expired
- 1982-03-09 DE DE8282301207T patent/DE3274064D1/de not_active Expired
- 1982-03-09 US US06/356,343 patent/US4472385A/en not_active Expired - Lifetime
- 1982-03-09 AT AT82301207T patent/ATE23269T1/de not_active IP Right Cessation
- 1982-03-09 CA CA000397937A patent/CA1170990A/en not_active Expired
- 1982-03-09 IT IT8220038A patent/IT1150639B/it active
- 1982-03-09 GB GB8206899A patent/GB2094145B/en not_active Expired

Also Published As

Publication number	Publication date
US4472385A (en)	1984-09-18
IT1150639B (it)	1986-12-17
AU550068B2 (en)	1986-02-27
AU8111482A (en)	1982-09-16
NO820742L (no)	1982-09-13
EP0060141A3 (en)	1983-08-24
EP0060141A2 (en)	1982-09-15
CH652031A5 (de)	1985-10-31
GB2094145A (en)	1982-09-15
EP0060141B1 (en)	1986-11-05
CA1170990A (en)	1984-07-17
NO157843B (no)	1988-02-22
FI820808L (fi)	1982-09-11
DE3274064D1 (en)	1986-12-11
FI78838C (fi)	1989-10-10
FI78838B (fi)	1989-06-30
ES8302462A1 (es)	1983-01-16
GB2094145B (en)	1984-12-05
ATE23269T1 (de)	1986-11-15
IE820536L (en)	1982-09-10
FR2501507B1 (it)	1986-04-18
IE52904B1 (en)	1988-04-13
FR2501507A1 (it)	1982-09-17
NO157843C (no)	1988-06-01
ES510245A0 (es)	1983-01-16

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19970326

Publication	Publication Date	Title
IT1178455B (it)	1987-09-09	Soluzioni di insulina stabilizzate e metodi per la loro produzione
FI822548A7 (fi)	1983-01-25	Inhalatiolääkkeen valmistustapa.
ES509183A0 (es)	1983-10-01	Procedimiento para la obtencion de derivados ciclicos de acido carbonico.
IT8223990A0 (it)	1982-10-29	Preparazioni di insulina stabilizzate e un procedimento per la loro preparazione.
IT7925027A0 (it)	1979-08-09	Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
FI851836A7 (fi)	1985-11-13	Uusien yhdisteiden valmistusmenetelmä.
IT1152146B (it)	1986-12-31	Procedimento per la produzione di nerofumo
FI851837A7 (fi)	1985-11-13	Uusien yhdisteiden valmistusmenetelmä.
IT1150897B (it)	1986-12-17	Procedimento per la fabbricazione di vulcanizzati
IT1210939B (it)	1989-09-29	Procedimento per la produzione di gamma-decalattone.
IT8125932A0 (it)	1981-12-31	Composizioni di plasmina stabilizzata e metodo per la loro preparazione.
IT8222784A0 (it)	1982-08-09	Processo per la preparazione di derivati dell'insulina.
RO83840A2 (ro)	1984-04-02	Procedeu pentru prepararea unor acizi alfa-arilalconici
IT1137176B (it)	1986-09-03	Procedimento per la produzione di dimetiletere
IT1154275B (it)	1987-01-21	Procedimento per la produzione di disolfuri di tiurame
FI822408A7 (fi)	1983-01-09	Menetelmä amidobentsamidien valmistamiseksi.
IT1154271B (it)	1987-01-21	Procedimento per la produzione di disolfuri di tiurama sostituiti
IT1182155B (it)	1987-09-30	Metodo per la produzione di un elettrodo
IT8520246A0 (it)	1985-04-05	Procedimento stereocontrollato per la produzione di acetossiazetidinone.
IT1158015B (it)	1987-02-18	Procedimento per la produzione di acido 6-idrossi-2-naftoico
IT8248055A0 (it)	1982-03-23	Procedimento per la produzione di ditiazolil-2(2.2')-disolfuri
RO87709A (ro)	1985-10-31	Procedeu pentru prepararea unor 1,1-alcandioli-carboxilati
MX156441A (es)	1988-08-23	Metodo mejorado para la produccion de acido fluormidrico
IT8421110A0 (it)	1984-05-25	Procedimento e impianto per laproduzione di etanolo.
FI852751A7 (fi)	1986-01-12	Menetelmä nitrovinkamiinihappojohdannaisten valmistamiseksi.