NO820742L - Fremgangsmaate for fremstilling av stabiliserte insulinpreparater - Google Patents

Fremgangsmaate for fremstilling av stabiliserte insulinpreparater

Info

Publication number: NO820742L
Authority: NO; Norway
Prior art keywords: procedure; preparation; insulin preparations; stabilized insulin; insulin
Prior art date: 1981-03-10

Application number

NO820742A

Other languages

English (en)

Other versions

NO157843B (no

NO157843C (no

Inventor

Jens Joergen Veilgaard Brange

Svend Havelund

Original Assignee

Novo Industri As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-03-10

Filing date

1982-03-09

Publication date

1982-09-13

1982-03-09 Application filed by Novo Industri As filed Critical Novo Industri As

1982-09-13 Publication of NO820742L publication Critical patent/NO820742L/no

1988-02-22 Publication of NO157843B publication Critical patent/NO157843B/no

1988-06-01 Publication of NO157843C publication Critical patent/NO157843C/no

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 8
102000004877 Insulin Human genes 0.000 title abstract 4
108090001061 Insulin Proteins 0.000 title abstract 4
229940125396 insulin Drugs 0.000 title abstract 4
238000002360 preparation method Methods 0.000 title abstract 3
238000000034 method Methods 0.000 title 1
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
229910052791 calcium Inorganic materials 0.000 abstract 1
239000011575 calcium Substances 0.000 abstract 1
229910052749 magnesium Inorganic materials 0.000 abstract 1
239000011777 magnesium Substances 0.000 abstract 1
159000000003 magnesium salts Chemical class 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
239000011701 zinc Substances 0.000 abstract 1
229910052725 zinc Inorganic materials 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)
Dental Preparations (AREA)

NO820742A 1981-03-10 1982-03-09 Fremgangsmaate for fremstilling av et opploest insulinpreparat. NO157843C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8107423		1981-03-10
DK414381		1981-09-18

Publications (3)

Publication Number	Publication Date
NO820742L true NO820742L (no)	1982-09-13
NO157843B NO157843B (no)	1988-02-22
NO157843C NO157843C (no)	1988-06-01

Family

ID=26067363

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO820742A NO157843C (no)	1981-03-10	1982-03-09	Fremgangsmaate for fremstilling av et opploest insulinpreparat.

Country Status (14)

Country	Link
US (1)	US4472385A (no)
EP (1)	EP0060141B1 (no)
AT (1)	ATE23269T1 (no)
AU (1)	AU550068B2 (no)
CA (1)	CA1170990A (no)
CH (1)	CH652031A5 (no)
DE (1)	DE3274064D1 (no)
ES (1)	ES510245A0 (no)
FI (1)	FI78838C (no)
FR (1)	FR2501507B1 (no)
GB (1)	GB2094145B (no)
IE (1)	IE52904B1 (no)
IT (1)	IT1150639B (no)
NO (1)	NO157843C (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1985002544A1 (en) *	1983-12-16	1985-06-20	Thomas Takemi Aoki	Insulin delivery algorithm
PH23446A (en) *	1986-10-20	1989-08-07	Novo Industri As	Peptide preparations
IE62879B1 (en) *	1987-02-25	1995-03-08	Novo Nordisk As	Novel insulin derivatives
US4789660A (en) *	1987-09-10	1988-12-06	American Home Products Corporation	Insulin administration using methyl and propyl paraben
BR9709845B1 (pt) †	1996-06-20	2008-11-18		preparaÇço aquosa de insulina, formulaÇço farmacÊutica parenteral, e, processso para aumentar a estabilidade quÍmica de uma preparaÇço de insulina.
AR012894A1 (es) *	1997-06-13	2000-11-22	Lilly Co Eli	Formulacion de insulina en solucion estable, su uso para preparar un medicamento y proceso para la preparacion de la misma.
WO1999034821A1 (en) *	1998-01-09	1999-07-15	Novo Nordisk A/S	Stabilised insulin compositions
US20020156434A1 (en) *	1998-03-13	2002-10-24	Minimed Inc.	Stabilizing catheter for protein drug delivery
JP5599543B2 (ja)	2002-05-07	2014-10-01	ノヴォノルディスクアー／エス	単量体インスリン及びアシル化インスリンを含む可溶性製剤
US20030226223A1 (en)	2002-06-11	2003-12-11	The Procter & Gamble Co.	High efficiency electric toothbrush
US7322066B2 (en)	2003-07-16	2008-01-29	Church & Dwight Co., Inc.	Electric toothbrushes having movable, intermittently movable, and fixed bristles
US20050053895A1 (en)	2003-09-09	2005-03-10	The Procter & Gamble Company Attention: Chief Patent Counsel	Illuminated electric toothbrushes emitting high luminous intensity toothbrush
US20050050659A1 (en)	2003-09-09	2005-03-10	The Procter & Gamble Company	Electric toothbrush comprising an electrically powered element
FR2896164B1 (fr) *	2006-01-18	2008-07-04	Flamel Technologies Sa	Formulation colloidale d'insuline longue action et sa preparation
FR2943538B1 (fr) *	2009-03-27	2011-05-20	Adocia	Formulation a action rapide d'insuline recombinante humaine
US9018190B2 (en)	2009-03-27	2015-04-28	Adocia	Functionalized oligosaccharides
US20130231281A1 (en)	2011-11-02	2013-09-05	Adocia	Rapid acting insulin formulation comprising an oligosaccharide
CN104902922B (zh)	2012-11-13	2017-12-12	阿道恰公司	包含经取代阴离子化合物的速效胰岛素制剂
WO2015120457A1 (en) *	2014-02-10	2015-08-13	Biodel Inc.	Stabilized ultra-rapid-acting insulin formulations
US9795678B2 (en)	2014-05-14	2017-10-24	Adocia	Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound
FR3020947B1 (fr)	2014-05-14	2018-08-31	Adocia	Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations
FR3043557B1 (fr)	2015-11-16	2019-05-31	Adocia	Composition a action rapide d'insuline comprenant un citrate substitue

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR892194A (fr) *	1938-06-29	1944-03-30	Ig Farbenindustrie Ag	Procédé de fabrication de préparations à base d'insuline
US2474729A (en) *	1945-01-03	1949-06-28	Rhone Poulenc Sa	Insulin preparations
US3102077A (en) *	1953-08-19	1963-08-27	Christensen Henry Marinus	Preparation of insulin containing 2.75 to 8 percent zinc content
DK98342C (da) *	1959-06-16	1964-03-31	Henry Marinus Dr Christensen	Fremgangsmåde til fremstilling af et insulinpræparat til peroral applikation.
US4196196A (en) *	1978-06-19	1980-04-01	Tiholiz Ivan C	Divalen/monovalent bipolar cation therapy for enhancement of tissue perfusion and reperfusion in disease states

1982
- 1982-03-04 AU AU81114/82A patent/AU550068B2/en not_active Ceased
- 1982-03-09 NO NO820742A patent/NO157843C/no unknown
- 1982-03-09 CH CH1447/82A patent/CH652031A5/de not_active IP Right Cessation
- 1982-03-09 CA CA000397937A patent/CA1170990A/en not_active Expired
- 1982-03-09 IE IE536/82A patent/IE52904B1/en not_active IP Right Cessation
- 1982-03-09 FR FR8203942A patent/FR2501507B1/fr not_active Expired
- 1982-03-09 ES ES82510245A patent/ES510245A0/es active Granted
- 1982-03-09 US US06/356,343 patent/US4472385A/en not_active Expired - Lifetime
- 1982-03-09 AT AT82301207T patent/ATE23269T1/de not_active IP Right Cessation
- 1982-03-09 IT IT8220038A patent/IT1150639B/it active
- 1982-03-09 GB GB8206899A patent/GB2094145B/en not_active Expired
- 1982-03-09 FI FI820808A patent/FI78838C/fi not_active IP Right Cessation
- 1982-03-09 EP EP82301207A patent/EP0060141B1/en not_active Expired
- 1982-03-09 DE DE8282301207T patent/DE3274064D1/de not_active Expired

Also Published As

Publication number	Publication date
EP0060141A3 (en)	1983-08-24
IT1150639B (it)	1986-12-17
CA1170990A (en)	1984-07-17
CH652031A5 (de)	1985-10-31
FR2501507A1 (no)	1982-09-17
AU8111482A (en)	1982-09-16
DE3274064D1 (en)	1986-12-11
NO157843B (no)	1988-02-22
NO157843C (no)	1988-06-01
US4472385A (en)	1984-09-18
FR2501507B1 (no)	1986-04-18
ATE23269T1 (de)	1986-11-15
EP0060141A2 (en)	1982-09-15
IE52904B1 (en)	1988-04-13
ES8302462A1 (es)	1983-01-16
FI820808L (fi)	1982-09-11
AU550068B2 (en)	1986-02-27
IT8220038A0 (it)	1982-03-09
FI78838C (fi)	1989-10-10
GB2094145A (en)	1982-09-15
IE820536L (en)	1982-09-10
EP0060141B1 (en)	1986-11-05
ES510245A0 (es)	1983-01-16
FI78838B (fi)	1989-06-30
GB2094145B (en)	1984-12-05

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