ES8401476A1 - Procedimiento para la preparacion de nuevas carboxamidas vinilogas. - Google Patents

Procedimiento para la preparacion de nuevas carboxamidas vinilogas.

Info

Publication number
ES8401476A1
ES8401476A1 ES520825A ES520825A ES8401476A1 ES 8401476 A1 ES8401476 A1 ES 8401476A1 ES 520825 A ES520825 A ES 520825A ES 520825 A ES520825 A ES 520825A ES 8401476 A1 ES8401476 A1 ES 8401476A1
Authority
ES
Spain
Prior art keywords
vinylogous
carboxamides
formula
preparing
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES520825A
Other languages
English (en)
Other versions
ES520825A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES8401476A1 publication Critical patent/ES8401476A1/es
Publication of ES520825A0 publication Critical patent/ES520825A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64Oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE CARBOXAMIDAS VINILOGAS, DE FORMULA (I), EN LA QUE X ES SULFINILO O SULFONILO; R1 ES FENILO O FENILO SUSTITUIDO; R3 ES HIDROGENO O ALCOHILO C1-3; Y R2 Y R4 PUEDEN SER VARIOS TIPOS DE RADICALES.CONSISTE EN LA REACCION DE OXIDACION DE UN COMPUESTO DE FORMULA (II) EN LA QUE Y ES AZUFRE O SULFINILO, Y LOS DEMAS RADICALES TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA OXIDACION SE LLEVA A CABO EN UN DISOLVENTE INERTE, CON UN OXIDANTE ADECUADO, TAL COMO PEROXIDO DE HIDROGENO, UN PERACIDO, METAPERYODATO, ETC., A UNATEMPERATURA ENTRE C80JC Y 120JC.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU EFECTO SOBRE EL SISTEMA NERVIOSO CENTRAL.
ES520825A 1982-04-06 1983-03-22 Procedimiento para la preparacion de nuevas carboxamidas vinilogas. Granted ES520825A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823212752 DE3212752A1 (de) 1982-04-06 1982-04-06 Neue vinyloge carboxamide, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES8401476A1 true ES8401476A1 (es) 1983-12-16
ES520825A0 ES520825A0 (es) 1983-12-16

Family

ID=6160342

Family Applications (1)

Application Number Title Priority Date Filing Date
ES520825A Granted ES520825A0 (es) 1982-04-06 1983-03-22 Procedimiento para la preparacion de nuevas carboxamidas vinilogas.

Country Status (13)

Country Link
US (1) US4536402A (es)
EP (1) EP0091041B1 (es)
JP (1) JPS58185580A (es)
AT (1) ATE20350T1 (es)
AU (1) AU556937B2 (es)
DE (2) DE3212752A1 (es)
DK (1) DK158733C (es)
ES (1) ES520825A0 (es)
FI (1) FI79309C (es)
IE (1) IE54793B1 (es)
IL (1) IL68285A0 (es)
NO (1) NO158255C (es)
ZA (1) ZA832381B (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3070606A (en) * 1962-12-25 Xchxn
DE2931010A1 (de) 1979-07-31 1981-02-26 Thomae Gmbh Dr K Neue vinyloge carboxamide, diese enthaltende arzneimittel und verfahren zur herstellung

Also Published As

Publication number Publication date
NO158255B (no) 1988-05-02
EP0091041A2 (de) 1983-10-12
AU556937B2 (en) 1986-11-27
DK158733B (da) 1990-07-09
DK87483D0 (da) 1983-02-24
IL68285A0 (en) 1983-07-31
DK87483A (da) 1983-10-07
ZA832381B (en) 1984-12-24
FI79309C (fi) 1989-12-11
IE830758L (en) 1983-10-06
US4536402A (en) 1985-08-20
EP0091041A3 (en) 1984-07-25
DK158733C (da) 1990-12-03
ES520825A0 (es) 1983-12-16
DE3212752A1 (de) 1983-10-13
FI79309B (fi) 1989-08-31
FI831056L (fi) 1983-10-07
NO158255C (no) 1988-08-10
DE3364034D1 (en) 1986-07-17
FI831056A0 (fi) 1983-03-29
EP0091041B1 (de) 1986-06-11
ATE20350T1 (de) 1986-06-15
IE54793B1 (en) 1990-02-14
AU1314583A (en) 1983-10-13
JPS58185580A (ja) 1983-10-29
NO831207L (no) 1983-10-07

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603