ES8502333A1 - Un procedimiento para la preparacion de una tableta farmaceutica - Google Patents

Un procedimiento para la preparacion de una tableta farmaceutica

Info

Publication number
ES8502333A1
ES8502333A1 ES524892A ES524892A ES8502333A1 ES 8502333 A1 ES8502333 A1 ES 8502333A1 ES 524892 A ES524892 A ES 524892A ES 524892 A ES524892 A ES 524892A ES 8502333 A1 ES8502333 A1 ES 8502333A1
Authority
ES
Spain
Prior art keywords
pharmaceutically acceptable
long
tablet formulations
matrix tablet
releases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524892A
Other languages
English (en)
Other versions
ES524892A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES524892A0 publication Critical patent/ES524892A0/es
Publication of ES8502333A1 publication Critical patent/ES8502333A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UNA TABLETA FARMACEUTICA FORMADA POR UN AGENTE TERAPEUTICO SOLUBLE EN ACIDOS EN UNA MATRIZ INSOLUBLE, LA CUAL LIBERA UNA GRAN CANTIDAD INICIAL DE AGENTE TERAPEUTICO Y DESPUES LIBERA DICHO AGENTE A UNA VELOCIDAD ESENCIALMENTE CONSTANTE.COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE JUNTAN UN COMPONENTE FARMACEUTICAMENTE ACEPTABLE, INSOLUBLE EN ACIDOS Y SOLUBLE EN BASES, QUE SE SELECCIONA ENTRE POLIMEROS Y ACIDOS GRASOS, UN ACIDO ORGANICO FARMACEUTICAMENTE ACEPTABLE Y POR LO MENOS UN EXCIPIENTE FARMACEUTICAMENTE ACEPTABLE; SEGUNDA, SE MEZCLAN ENTRE SI LOS INGREDIENTES CITADOS, COMPONENTES DE LA TABLETA; Y POR ULTIMO, SE COMPRIMEN DICHOS EXCIPIENTES PARA OBTENER TABLETAS DE TAMAN/O DESEADO.
ES524892A 1982-08-12 1983-08-11 Un procedimiento para la preparacion de una tableta farmaceutica Expired ES8502333A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/407,511 US4704284A (en) 1982-08-12 1982-08-12 Long-acting matrix tablet formulations

Publications (2)

Publication Number Publication Date
ES524892A0 ES524892A0 (es) 1985-01-01
ES8502333A1 true ES8502333A1 (es) 1985-01-01

Family

ID=23612384

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524892A Expired ES8502333A1 (es) 1982-08-12 1983-08-11 Un procedimiento para la preparacion de una tableta farmaceutica

Country Status (17)

Country Link
US (1) US4704284A (es)
EP (1) EP0103387A3 (es)
JP (1) JPS5948415A (es)
KR (1) KR860000840B1 (es)
AU (1) AU546249B2 (es)
CA (1) CA1214391A (es)
DK (1) DK365883A (es)
EG (1) EG16065A (es)
ES (1) ES8502333A1 (es)
FI (1) FI82186C (es)
GR (1) GR78921B (es)
GT (1) GT198303076A (es)
NO (1) NO169818C (es)
NZ (1) NZ205205A (es)
PH (1) PH18211A (es)
PT (1) PT77185B (es)
ZA (1) ZA835900B (es)

Families Citing this family (30)

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JPH0729927B2 (ja) * 1983-04-09 1995-04-05 日研化学株式会社 テオフィリン徐放性製剤
IE58246B1 (en) * 1984-12-21 1993-08-11 Byk Gulden Lomberg Chem Fab Theophylline sustained release formulation
FR2585246A1 (fr) * 1985-07-26 1987-01-30 Cortial Procede d'obtention de formes pharmaceutiques solides a liberation prolongee
US5188840A (en) * 1985-09-26 1993-02-23 Chugai Seiyaku Kabushiki Kaisha Slow-release pharmaceutical agent
US4837032A (en) * 1986-02-04 1989-06-06 Farval Ag Theophylline sustained release tablet
US4820523A (en) * 1986-04-15 1989-04-11 Warner-Lambert Company Pharmaceutical composition
JPH0776172B2 (ja) * 1986-04-16 1995-08-16 藤沢薬品工業株式会社 マトリツクス錠
US4917892A (en) * 1988-06-28 1990-04-17 Temple University Encapsulated topical delivery system
DK469989D0 (da) * 1989-09-22 1989-09-22 Bukh Meditec Farmaceutisk praeparat
US5364646A (en) * 1990-01-10 1994-11-15 Dr. Karl Thomae Gmbh Oral pharmaceutical forms of pimobendan
US5431922A (en) * 1991-03-05 1995-07-11 Bristol-Myers Squibb Company Method for administration of buspirone
US5160742A (en) * 1991-12-31 1992-11-03 Abbott Laboratories System for delivering an active substance for sustained release
MX9300110A (es) * 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.
US20070082918A1 (en) * 1993-11-02 2007-04-12 Naftchi N E Neurologically active compounds and compounds with multiple activities
US5478572A (en) * 1994-09-06 1995-12-26 Bristol-Myers Squibb Co. Gepirone dosage form
DE19631084A1 (de) * 1996-08-01 1998-02-05 Basf Ag Verwendung von (Meth)acrylsäure-Copolymeren zur Erhöhung der Permeabilität der Schleimhaut
US6028929A (en) * 1997-11-14 2000-02-22 Tellabs Operations, Inc. Echo canceller employing dual-H architecture having improved non-linear echo path detection
US20020106408A1 (en) * 2000-12-01 2002-08-08 Johnatan Bacon Prolamin-based sustained-release compositions and delayed-onset compositions
BRPI0307786B8 (pt) * 2002-02-26 2021-05-25 Astrazeneca Ab composição farmacêutica, método para preparar a mesma, métodos para inibir a taxa de precipitação do agente da solução no trato gi, e para reduzir variabilidade inter-pacientes no que se refere à biodisponibilidade e/ou concentrações plásmáticas do agente, e, uso de um celulose éter solúvel em água ou de um éster de um celulose éter solúvel em água
US20060093661A1 (en) * 2002-05-07 2006-05-04 Kapac, Llc Methods and formulations for enhancing the absorption and gastro-intestinal bioavailability of hydrophobic drugs
GB0317663D0 (en) * 2003-07-29 2003-09-03 Astrazeneca Ab Pharmaceutical composition
AU2004264958B2 (en) 2003-08-13 2010-04-15 Biocon, Ltd Micro-particle fatty acid salt solid dosage formulations for therapeutic agents
US20050215561A1 (en) * 2004-03-19 2005-09-29 Krishnendu Ghosh Pharmaceutical dosage forms and compositions
EP1579862A1 (en) 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
EP1920785A1 (en) 2006-11-07 2008-05-14 Boehringer Ingelheim Vetmedica Gmbh Liquid preparation comprising a complex of pimobendan and cyclodextrin
HUE060093T2 (hu) 2012-03-15 2023-01-28 Boehringer Ingelheim Vetmedica Gmbh Gyógyszerészeti tablettakészítmény az állatgyógyászati ágazat számára, eljárás annak elõállítására és annak alkalmazása
HUE054186T2 (hu) 2013-07-19 2021-08-30 Boehringer Ingelheim Vetmedica Gmbh Éterezett ciklodextrin-származékokat tartalmazó, tartósított, folyékony, vizes gyógyászati készítmény
ES2883448T3 (es) 2013-12-04 2021-12-07 Boehringer Ingelheim Vetmedica Gmbh Composiciones farmacéuticas mejoradas de pimobendán
US10537570B2 (en) 2016-04-06 2020-01-21 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2793979A (en) * 1953-03-30 1957-05-28 Smith Kline French Lab Method of making a sustained release pharmaceutical tablet and product of the method
US2953497A (en) * 1953-06-03 1960-09-20 Howard A Press Therapeutic tablets
US3044938A (en) * 1955-07-01 1962-07-17 Sandoz Chemical Works Inc Sustained action pharmaceutical tablets
US2809917A (en) * 1955-10-17 1957-10-15 Victor M Hermelin Sustained release pharmaceutical tablets
NL109293C (es) * 1955-12-22
US3039933A (en) * 1957-10-07 1962-06-19 Premo Pharmaceutical Lab Inc Ethyl cellulose-polyethylene glycol tablet matrix
US2993836A (en) * 1958-02-20 1961-07-25 Dow Chemical Co Sustained release tablets
US2956926A (en) * 1958-09-23 1960-10-18 American Cyanamid Co Coated citric acid particles
US2987445A (en) * 1958-10-10 1961-06-06 Rohm & Haas Drug composition
US3087860A (en) * 1958-12-19 1963-04-30 Abbott Lab Method of prolonging release of drug from a precompressed solid carrier
US2951792A (en) * 1959-11-18 1960-09-06 Smith Kline French Lab Sustained release pharmaceutical tablets
NL113366C (es) * 1961-02-24
US3115441A (en) * 1962-06-06 1963-12-24 Victor M Hermelin Timed release pharmaceutical preparations and method of making the same
US3336200A (en) * 1963-05-28 1967-08-15 Warner Lambert Pharmaceutical Tablet structure
NL297631A (es) * 1963-06-03
US3400197A (en) * 1965-01-26 1968-09-03 Robins Co Inc A H Compressible sustained release pharmaceutical tablet lipid-colloidal silica gel matrix fragment granules
FR1545612A (fr) * 1967-06-15 1968-11-15 Dausse Lab Procédé de fabrication de comprimés
US3577514A (en) * 1968-06-10 1971-05-04 Pfizer Sustained release pharmaceutical tablets
US3608063A (en) * 1969-08-15 1971-09-21 Gilbert S Banker Molecular drug entrapment process and compositions
US3632739A (en) * 1969-12-29 1972-01-04 Sandoz Ag Solid sustained release pharmaceutical preparation
US3669968A (en) * 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines
US3906086A (en) * 1971-07-19 1975-09-16 Richard G Powers Timed-release aspirin
DE2336218C3 (de) * 1973-07-17 1985-11-14 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz Orale Arzneiform
US4012498A (en) * 1974-03-27 1977-03-15 Sandoz, Inc. Sustained release tablet formulations
US3939259A (en) * 1974-05-24 1976-02-17 Anthony Pescetti Coating composition and therapeutic preparation incorporating same
US3978203A (en) * 1974-07-12 1976-08-31 Dynatech Corporation Sustained release of pharmaceuticals from polyester matrices
US4171363A (en) * 1977-02-22 1979-10-16 Bristol-Myers Company 1,2,3-Thiadiazole process
US4122157A (en) * 1977-03-04 1978-10-24 Richardson-Merrell Inc. Nitrofurantoin sustained release tablet
US4130647A (en) * 1977-07-08 1978-12-19 Pfizer Inc. Methods for treating congestive heart failure and ischemic heart disease
DD146547A5 (de) * 1978-07-15 1981-02-18 Boehringer Sohn Ingelheim Arzneimittel-retardform mit unloeslichen poroesen diffusionshuellen
JPS55153715A (en) * 1979-05-18 1980-11-29 Nikken Kagaku Kk Prolonged granule of theophylline
US4361545A (en) * 1979-05-21 1982-11-30 Rowell Laboratories, Inc. Solid pharmaceutical formulations for slow, zero order release via controlled surface erosion
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
JPS5649314A (en) * 1979-07-05 1981-05-02 Yamanouchi Pharmaceut Co Ltd Lasting pharmaceutical composition having prolonged action and its preparation
US4248856A (en) * 1979-07-10 1981-02-03 American Home Products Corporation Sustained release pharmaceutical compositions
DE3000979A1 (de) * 1980-01-12 1981-07-23 Dr. Karl Thomae Gmbh, 7950 Biberach Neue dipyridamol-retardformen und verfahren zu ihrer herstellung
JPS56122311A (en) * 1980-02-29 1981-09-25 Eisai Co Ltd Lasting theophylline pharmaceutical composition

Also Published As

Publication number Publication date
GT198303076A (es) 1985-01-30
EP0103387A3 (en) 1984-12-12
ZA835900B (en) 1985-03-27
US4704284A (en) 1987-11-03
PT77185A (en) 1983-09-01
FI82186C (fi) 1991-02-11
AU1788683A (en) 1984-02-16
EG16065A (en) 1986-12-30
KR840005661A (ko) 1984-11-15
FI832895L (fi) 1984-02-13
NO169818B (no) 1992-05-04
EP0103387A2 (en) 1984-03-21
NZ205205A (en) 1986-06-11
GR78921B (es) 1984-10-02
FI82186B (fi) 1990-10-31
FI832895A0 (fi) 1983-08-11
CA1214391A (en) 1986-11-25
PT77185B (en) 1986-07-11
ES524892A0 (es) 1985-01-01
AU546249B2 (en) 1985-08-22
PH18211A (en) 1985-04-30
JPS5948415A (ja) 1984-03-19
KR860000840B1 (ko) 1986-07-09
NO169818C (no) 1992-08-12
DK365883D0 (da) 1983-08-11
DK365883A (da) 1984-02-13
NO832883L (no) 1984-02-13

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303