ES8609351A1 - Procedimiento para la preparacion de composiciones farmaceuticas hidrosolubles a base de sales del acido (-) cis-1, 2-epoxi-propilfosfonico. - Google Patents

Procedimiento para la preparacion de composiciones farmaceuticas hidrosolubles a base de sales del acido (-) cis-1, 2-epoxi-propilfosfonico.

Info

Publication number: ES8609351A1
Authority: ES; Spain
Prior art keywords: hydrosoluble; pharmaceutical compositions; antibiotic pharmaceutical; antibiotic; salified
Prior art date: 1984-10-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES547625A

Other languages

English (en)

Spanish (es)

Other versions

ES547625A0 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Schering SpA

Original Assignee

Schering SpA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-05

Filing date

1985-10-04

Publication date

1986-09-01

1985-10-04 Application filed by Schering SpA filed Critical Schering SpA

1986-09-01 Publication of ES547625A0 publication Critical patent/ES547625A0/es

1986-09-01 Publication of ES8609351A1 publication Critical patent/ES8609351A1/es

Status Expired legal-status Critical Current

Links

230000003115 biocidal effect Effects 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
235000001014 amino acid Nutrition 0.000 abstract 2
150000001413 amino acids Chemical class 0.000 abstract 2
239000004475 Arginine Substances 0.000 abstract 1
XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 abstract 1
AHLPHDHHMVZTML-BYPYZUCNSA-N L-Ornithine Chemical compound NCCC[C@H](N)C(O)=O AHLPHDHHMVZTML-BYPYZUCNSA-N 0.000 abstract 1
ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 abstract 1
KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 1
239000004472 Lysine Substances 0.000 abstract 1
KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
AHLPHDHHMVZTML-UHFFFAOYSA-N Orn-delta-NH2 Natural products NCCCC(N)C(O)=O AHLPHDHHMVZTML-UHFFFAOYSA-N 0.000 abstract 1
UTJLXEIPEHZYQJ-UHFFFAOYSA-N Ornithine Natural products OC(=O)C(C)CCCN UTJLXEIPEHZYQJ-UHFFFAOYSA-N 0.000 abstract 1
ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 1
235000018417 cysteine Nutrition 0.000 abstract 1
XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229960003104 ornithine Drugs 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
- C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Oil, Petroleum & Natural Gas (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Dermatology (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ES547625A 1984-10-05 1985-10-04 Procedimiento para la preparacion de composiciones farmaceuticas hidrosolubles a base de sales del acido (-) cis-1, 2-epoxi-propilfosfonico. Expired ES8609351A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH4792/84A CH660306A5 (de)	1984-10-05	1984-10-05	Wasserloesliche pharmazeutische zusammensetzungen auf der basis von salzen der (-)cis-1,2-epoxypropylphosphonsaeure mit aminosaeuren.

Publications (2)

Publication Number	Publication Date
ES547625A0 ES547625A0 (es)	1986-09-01
ES8609351A1 true ES8609351A1 (es)	1986-09-01

Family

ID=4282621

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES547625A Expired ES8609351A1 (es)	1984-10-05	1985-10-04	Procedimiento para la preparacion de composiciones farmaceuticas hidrosolubles a base de sales del acido (-) cis-1, 2-epoxi-propilfosfonico.

Country Status (11)

Country	Link
JP (1)	JPS62223121A (de)
KR (1)	KR860003012A (de)
AT (1)	AT383736B (de)
BE (1)	BE903369A (de)
CH (1)	CH660306A5 (de)
DE (1)	DE3535356A1 (de)
ES (1)	ES8609351A1 (de)
FR (1)	FR2571255B1 (de)
GB (1)	GB2165152B (de)
IT (1)	IT1201479B (de)
NL (1)	NL8502712A (de)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH310498A (de) *	1951-11-14	1955-10-31	Waldhof Zellstoff Fab	Verfahren zur Stabilisierung von Alkalisalzen von Adenosinpolyphosphorsäuren.
DE1767212B1 (de) *	1967-04-13	1971-05-06	Sumitomo Chemical Co	Verfahren zur Herstellung injizierbarer Arzneimittel
US3639590A (en) *	1967-07-25	1972-02-01	Merck & Co Inc	Antibacterial composition containing (-) (cis-1 2-epoxypropyl) phosphoric acid
BE756953A (fr) *	1969-10-02	1971-04-01	Merck & Co Inc	Potentialisation d'antibiotiques
IT1161974B (it) *	1978-02-02	1987-03-18	Italchemi Spa	Derivti dell acido cis.i 2 epossipropilfosfonico loro procedimento di preparazione e composizioni farmaceutiche che li contengono
DE2813814A1 (de) *	1978-03-31	1979-10-18	Boehringer Mannheim Gmbh	Hochwirksame, enteral resorbierbare pharmazeutische praeparate
IT1112282B (it) *	1978-07-19	1986-01-13	Zambon Spa	Bis-(2-ammonio-2-idrossimetil-1,3-propandiolo)(2r-cis)-(3-metilossiranil)fosfonato
IT1097578B (it) *	1978-07-31	1985-08-31	Italchemi Spa	Metodo per la preparazione di sali dell'acido (-)
US4235900A (en) *	1978-11-15	1980-11-25	E. R. Squibb & Sons, Inc.	Cephradine compositions

1984
- 1984-10-05 CH CH4792/84A patent/CH660306A5/de not_active IP Right Cessation
1985
- 1985-10-02 JP JP60219969A patent/JPS62223121A/ja active Pending
- 1985-10-03 AT AT0287185A patent/AT383736B/de not_active IP Right Cessation
- 1985-10-03 DE DE19853535356 patent/DE3535356A1/de not_active Withdrawn
- 1985-10-04 GB GB08524550A patent/GB2165152B/en not_active Expired
- 1985-10-04 NL NL8502712A patent/NL8502712A/nl not_active Application Discontinuation
- 1985-10-04 ES ES547625A patent/ES8609351A1/es not_active Expired
- 1985-10-04 IT IT22367/85A patent/IT1201479B/it active
- 1985-10-04 BE BE2/60807A patent/BE903369A/nl not_active IP Right Cessation
- 1985-10-05 KR KR1019850007328A patent/KR860003012A/ko not_active Abandoned
- 1985-10-07 FR FR8514800A patent/FR2571255B1/fr not_active Expired

Also Published As

Publication number	Publication date
GB2165152A (en)	1986-04-09
ES547625A0 (es)	1986-09-01
AT383736B (de)	1987-08-10
GB8524550D0 (en)	1985-11-06
DE3535356A1 (de)	1986-04-24
NL8502712A (nl)	1986-05-01
KR860003012A (ko)	1986-05-19
ATA287185A (de)	1987-01-15
FR2571255A1 (fr)	1986-04-11
JPS62223121A (ja)	1987-10-01
BE903369A (nl)	1986-02-03
IT1201479B (it)	1989-02-02
IT8522367A0 (it)	1985-10-04
GB2165152B (en)	1988-03-16
FR2571255B1 (fr)	1988-09-16
CH660306A5 (de)	1987-04-15

Publication	Publication Date	Title
ES8801930A1 (es)	1988-03-16	Procedimiento para la preparacion de dipeptidos de n,n'-dialquilguanidino
GR3018228T3 (en)	1996-02-29	Homogeneous mammalian hematopoietic stem cell composition.
IE45390L (en)	1977-12-18	Anti-caries composition
PT82127A (en)	1986-04-01	Process for the preparation of phenyl carbamates
DE3271532D1 (en)	1986-07-10	Salts of n-substituted-2-pyrrolidone-4-carboxylic acids as humectants
CA2015186A1 (en)	1990-10-24	Nutrient composition
SE8901041L (sv)	1989-09-24	Antitrombotiska farmaceutiska preparat samt foerfarande foer deras framstaellning
GB2181647B (en)	1989-10-11	Compositions based on lysine and arginine salts.
DE3582895D1 (de)	1991-06-27	Peptid, dessen herstellung und benutzung.
AU4629885A (en)	1986-04-10	4,5-dihydro-4-oxo-2-((2-trans-phenylcyclopropyl) amino)-3- furancarboxylic acid derivatives
ES8609351A1 (es)	1986-09-01	Procedimiento para la preparacion de composiciones farmaceuticas hidrosolubles a base de sales del acido (-) cis-1, 2-epoxi-propilfosfonico.
MY101821A (en)	1992-01-31	Quinazolinediones and pyridopyrimidinediones
IL84551A0 (en)	1988-04-29	Peptides,their preparation and pharmaceutical compositions containing them
ES8608861A1 (es)	1986-09-01	Procedimiento para la preparacion de composiciones farmaceuticas hidrosolubles a base de sales de fosfomicina.
GB1051686A (de)
AU544742B2 (en)	1985-06-13	Prepare amides especially peptides
DE2965364D1 (en)	1983-06-16	Alpha-difluoromethyl amino acids and pharmaceutical composition containing the same
JPS6463342A (en)	1989-03-09	Stabilization of glutathione-containing composition
ES2000182A6 (es)	1988-01-01	Procedimiento para la obtencion de (iso) ureas substituidas potenciadoras del rendimiento.
JPS5332193A (en)	1978-03-27	Preparation of l-glutamic acid by fermentation
ES8606259A1 (es)	1986-04-01	Un metodo de producir una composicion farmaceutica que contiene isoxicamato de l-arginina como ingrediente activo.
ES8308832A1 (es)	1983-10-16	Procedimiento para preparar derivados fluorados de diaminohepteno o -heptina.
ES8606248A1 (es)	1986-04-01	Un procedimiento para la produccion de una dihidroxifenil- glicina opticamente activa
ES2051788T3 (es)	1994-07-01	Un producto farmaceutico.
AU6387886A (en)	1987-04-16	Mitogenic peptides