JPS62223121A - （−）シス−１，２−エポキシプロピルホスホン酸のアミノ酸塩を基体とした水溶性医薬組成物 - Google Patents

（−）シス−１，２−エポキシプロピルホスホン酸のアミノ酸塩を基体とした水溶性医薬組成物

Info

Publication number
JPS62223121A
JPS62223121A JP60219969A JP21996985A JPS62223121A JP S62223121 A JPS62223121 A JP S62223121A JP 60219969 A JP60219969 A JP 60219969A JP 21996985 A JP21996985 A JP 21996985A JP S62223121 A JPS62223121 A JP S62223121A
Authority
JP
Japan
Prior art keywords
amino acid
acid
cis
epoxypropylphosphonic
water soluble
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP60219969A
Other languages
English (en)
Japanese (ja)
Inventor
ステフアニア　メオラ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seuref AG
Original Assignee
Seuref AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seuref AG filed Critical Seuref AG
Publication of JPS62223121A publication Critical patent/JPS62223121A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
    • C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP60219969A 1984-10-05 1985-10-02 （−）シス−１，２−エポキシプロピルホスホン酸のアミノ酸塩を基体とした水溶性医薬組成物 Pending JPS62223121A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH4792/84A CH660306A5 (de) 1984-10-05 1984-10-05 Wasserloesliche pharmazeutische zusammensetzungen auf der basis von salzen der (-)cis-1,2-epoxypropylphosphonsaeure mit aminosaeuren.
CH4792/84-2 1984-10-05

Publications (1)

Publication Number Publication Date
JPS62223121A true JPS62223121A (ja) 1987-10-01

Family

ID=4282621

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60219969A Pending JPS62223121A (ja) 1984-10-05 1985-10-02 （−）シス−１，２−エポキシプロピルホスホン酸のアミノ酸塩を基体とした水溶性医薬組成物

Country Status (11)

Country Link
JP (1) JPS62223121A (de)
KR (1) KR860003012A (de)
AT (1) AT383736B (de)
BE (1) BE903369A (de)
CH (1) CH660306A5 (de)
DE (1) DE3535356A1 (de)
ES (1) ES8609351A1 (de)
FR (1) FR2571255B1 (de)
GB (1) GB2165152B (de)
IT (1) IT1201479B (de)
NL (1) NL8502712A (de)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54109922A (en) * 1978-02-02 1979-08-29 Italchemi Spa *****cis**1*22epoxypropyl phosphonic acid salts* their manufacture and antibiotic chemicaltherapeutical drug containing it as active component

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH310498A (de) * 1951-11-14 1955-10-31 Waldhof Zellstoff Fab Verfahren zur Stabilisierung von Alkalisalzen von Adenosinpolyphosphorsäuren.
DE1767212B1 (de) * 1967-04-13 1971-05-06 Sumitomo Chemical Co Verfahren zur Herstellung injizierbarer Arzneimittel
US3639590A (en) * 1967-07-25 1972-02-01 Merck & Co Inc Antibacterial composition containing (-) (cis-1 2-epoxypropyl) phosphoric acid
BE756953A (fr) * 1969-10-02 1971-04-01 Merck & Co Inc Potentialisation d'antibiotiques
DE2813814A1 (de) * 1978-03-31 1979-10-18 Boehringer Mannheim Gmbh Hochwirksame, enteral resorbierbare pharmazeutische praeparate
IT1112282B (it) * 1978-07-19 1986-01-13 Zambon Spa Bis-(2-ammonio-2-idrossimetil-1,3-propandiolo)(2r-cis)-(3-metilossiranil)fosfonato
IT1097578B (it) * 1978-07-31 1985-08-31 Italchemi Spa Metodo per la preparazione di sali dell'acido (-)
US4235900A (en) * 1978-11-15 1980-11-25 E. R. Squibb & Sons, Inc. Cephradine compositions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54109922A (en) * 1978-02-02 1979-08-29 Italchemi Spa *****cis**1*22epoxypropyl phosphonic acid salts* their manufacture and antibiotic chemicaltherapeutical drug containing it as active component

Also Published As

Publication number Publication date
GB2165152A (en) 1986-04-09
ES547625A0 (es) 1986-09-01
AT383736B (de) 1987-08-10
GB8524550D0 (en) 1985-11-06
DE3535356A1 (de) 1986-04-24
NL8502712A (nl) 1986-05-01
KR860003012A (ko) 1986-05-19
ATA287185A (de) 1987-01-15
FR2571255A1 (fr) 1986-04-11
BE903369A (nl) 1986-02-03
ES8609351A1 (es) 1986-09-01
IT1201479B (it) 1989-02-02
IT8522367A0 (it) 1985-10-04
GB2165152B (en) 1988-03-16
FR2571255B1 (fr) 1988-09-16
CH660306A5 (de) 1987-04-15

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