FI104176B1 - Förfarande för framställning av nya antivirala fosfolipidderivat av nukleosider - Google Patents

Förfarande för framställning av nya antivirala fosfolipidderivat av nukleosider

Info

Publication number
FI104176B1
FI104176B1 FI930753A FI930753A FI104176B1 FI 104176 B1 FI104176 B1 FI 104176B1 FI 930753 A FI930753 A FI 930753A FI 930753 A FI930753 A FI 930753A FI 104176 B1 FI104176 B1 FI 104176B1
Authority
FI
Finland
Prior art keywords
preparation
nucleosides
phospholipid derivatives
novel antiviral
compounds
Prior art date
Application number
FI930753A
Other languages
English (en)
Finnish (fi)
Other versions
FI930753L (fi
FI104176B (sv
FI930753A0 (fi
Inventor
Harald Zilch
Herbert Leinert
Alfred Mertens
Dieter Herrmann
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25896049&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI104176(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of FI930753L publication Critical patent/FI930753L/fi
Publication of FI930753A0 publication Critical patent/FI930753A0/fi
Application granted granted Critical
Publication of FI104176B publication Critical patent/FI104176B/sv
Publication of FI104176B1 publication Critical patent/FI104176B1/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/10Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI930753A 1990-08-20 1993-02-19 Förfarande för framställning av nya antivirala fosfolipidderivat av nukleosider FI104176B1 (sv)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE4026265A DE4026265A1 (de) 1990-08-20 1990-08-20 Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
DE4026265 1990-08-20
EP9101541 1991-08-14
PCT/EP1991/001541 WO1992003462A1 (de) 1990-08-20 1991-08-14 Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
US66103896 1996-06-10
US08/661,038 US5756711A (en) 1990-08-20 1996-06-10 Phospholipid derivatives of nucleosides and their use as anti-viral medicaments

Publications (4)

Publication Number Publication Date
FI930753L FI930753L (fi) 1993-02-19
FI930753A0 FI930753A0 (fi) 1993-02-19
FI104176B FI104176B (sv) 1999-11-30
FI104176B1 true FI104176B1 (sv) 1999-11-30

Family

ID=25896049

Family Applications (1)

Application Number Title Priority Date Filing Date
FI930753A FI104176B1 (sv) 1990-08-20 1993-02-19 Förfarande för framställning av nya antivirala fosfolipidderivat av nukleosider

Country Status (15)

Country Link
US (1) US5756711A (sv)
EP (1) EP0545966B1 (sv)
CN (1) CN1032258C (sv)
AT (1) ATE114316T1 (sv)
CA (1) CA2090024C (sv)
DE (2) DE4026265A1 (sv)
DK (1) DK0545966T3 (sv)
ES (1) ES2066461T3 (sv)
FI (1) FI104176B1 (sv)
HK (1) HK35597A (sv)
IE (1) IE64374B1 (sv)
NO (1) NO179710C (sv)
PT (1) PT98720B (sv)
SK (1) SK281826B6 (sv)
WO (1) WO1992003462A1 (sv)

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Also Published As

Publication number Publication date
AU654670B2 (en) 1994-11-17
FI930753L (fi) 1993-02-19
NO179710B (no) 1996-08-26
DE4026265A1 (de) 1992-02-27
SK281826B6 (sk) 2001-08-06
NO179710C (no) 1996-12-04
ATE114316T1 (de) 1994-12-15
HK35597A (en) 1997-03-27
ES2066461T3 (es) 1995-03-01
FI104176B (sv) 1999-11-30
SK9293A3 (en) 1993-07-07
CN1059149A (zh) 1992-03-04
DK0545966T3 (da) 1995-05-08
CN1032258C (zh) 1996-07-10
PT98720B (pt) 1999-02-26
EP0545966B1 (de) 1994-11-23
DE59103595D1 (de) 1995-01-05
US5756711A (en) 1998-05-26
NO930587L (no) 1993-02-19
NO930587D0 (no) 1993-02-19
IE64374B1 (en) 1995-07-26
EP0545966A1 (de) 1993-06-16
IE912930A1 (en) 1992-02-26
WO1992003462A1 (de) 1992-03-05
AU8325191A (en) 1992-03-17
PT98720A (pt) 1992-07-31
CA2090024A1 (en) 1992-02-21
CA2090024C (en) 2000-05-02
FI930753A0 (fi) 1993-02-19

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