FI104233B1 - Menetelmä stabiilien, interleukiineja sisältävien rokotekoostumusten valmistamiseksi - Google Patents
Menetelmä stabiilien, interleukiineja sisältävien rokotekoostumusten valmistamiseksiInfo
- Publication number
- FI104233B1 FI104233B1 FI920132A FI920132A FI104233B1 FI 104233 B1 FI104233 B1 FI 104233B1 FI 920132 A FI920132 A FI 920132A FI 920132 A FI920132 A FI 920132A FI 104233 B1 FI104233 B1 FI 104233B1
- Authority
- FI
- Finland
- Prior art keywords
- vaccine compositions
- preparation
- compositions containing
- interleukins
- interleukin
- Prior art date
Links
- 102000015696 Interleukins Human genes 0.000 title abstract 5
- 108010063738 Interleukins Proteins 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 3
- 229940047122 interleukins Drugs 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 3
- 239000011707 mineral Substances 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 229940037003 alum Drugs 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37974289A | 1989-07-14 | 1989-07-14 | |
| US37974289 | 1989-07-14 | ||
| PCT/US1990/003982 WO1991001143A1 (en) | 1989-07-14 | 1990-07-16 | Stable vaccine compositions containing interleukins |
| US9003982 | 1990-07-16 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI920132A0 FI920132A0 (fi) | 1992-01-13 |
| FI104233B FI104233B (fi) | 1999-12-15 |
| FI104233B1 true FI104233B1 (fi) | 1999-12-15 |
Family
ID=23498494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI920132A FI104233B1 (fi) | 1989-07-14 | 1992-01-13 | Menetelmä stabiilien, interleukiineja sisältävien rokotekoostumusten valmistamiseksi |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0482076B1 (de) |
| JP (2) | JP3485184B2 (de) |
| KR (1) | KR0177179B1 (de) |
| AT (1) | ATE121629T1 (de) |
| AU (1) | AU648509B2 (de) |
| CA (1) | CA2063587C (de) |
| DE (1) | DE69018990T2 (de) |
| DK (1) | DK0482076T3 (de) |
| ES (1) | ES2075900T3 (de) |
| FI (1) | FI104233B1 (de) |
| NO (1) | NO301577B1 (de) |
| WO (1) | WO1991001143A1 (de) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6642390A (en) * | 1989-10-27 | 1991-05-31 | Arch Development Corporation | Methods and compositions for promoting immunopotentiation |
| US6406696B1 (en) | 1989-10-27 | 2002-06-18 | Tolerance Therapeutics, Inc. | Methods of stimulating the immune system with anti-CD3 antibodies |
| GR1000881B (el) * | 1990-08-06 | 1993-03-16 | Praxis Biolog Inc | Σταθερες συνθεσεις εμβολιου που περιεχουν ιντερλευκινες. |
| ZA919907B (en) * | 1990-12-19 | 1992-08-26 | Schering Corp | Use of il-4 to enhance immune response to immunogens in vaccines |
| JPH07500813A (ja) * | 1991-05-13 | 1995-01-26 | リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア | リポソーム多糖体ワクチン |
| DE4126983A1 (de) | 1991-08-15 | 1993-02-18 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von humanprotein-enthaltenden, konservierten arzneimitteln fuer infusions- oder injektionszwecke |
| EP0655927B1 (de) * | 1992-08-10 | 1997-04-23 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Interleukin-4 stimulierter t-lymphozyten-zelltod |
| ZA936095B (en) * | 1992-08-21 | 1994-03-14 | Univ Melbourne | Cytokine applications. |
| US6491916B1 (en) | 1994-06-01 | 2002-12-10 | Tolerance Therapeutics, Inc. | Methods and materials for modulation of the immunosuppresive activity and toxicity of monoclonal antibodies |
| AU3541495A (en) * | 1994-09-01 | 1996-03-22 | Wisconsin Alumni Research Foundation | Therapeutic remodeling in aids |
| US6509313B1 (en) * | 1996-02-28 | 2003-01-21 | Cornell Research Foundation, Inc. | Stimulation of immune response with low doses of cytokines |
| DE69735856T2 (de) * | 1996-05-31 | 2006-11-16 | National University Of Ireland Maynooth, Maynooth | Il-12 als adjuvanz für bordetella pertussis impfstoffe |
| TW586934B (en) * | 1997-05-19 | 2004-05-11 | Sumitomo Pharma | Immunopotentiating composition |
| US6270758B1 (en) | 1998-10-08 | 2001-08-07 | Duke University | Substantially non-toxic biologically active mucosal adjuvants in vertebrate subjects |
| US6027731A (en) * | 1998-11-17 | 2000-02-22 | Wisconsin Alumni Research Foundation | Pertussis toxin induced lymphocytosis |
| IT1302534B1 (it) | 1998-12-21 | 2000-09-05 | Fidia Advanced Biopolymers Srl | Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per |
| SK782002A3 (en) * | 1999-07-21 | 2003-08-05 | Lexigen Pharm Corp | FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens |
| AU1813701A (en) | 1999-12-03 | 2001-06-12 | Celltech Chiroscience Limited | Interleukin-1 muteins useful as vaccine adjuvants |
| US8663634B2 (en) | 2005-07-11 | 2014-03-04 | Macrogenics, Inc. | Methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity |
| WO2007039584A1 (en) * | 2005-09-30 | 2007-04-12 | Lipoxen Technologies Limited | Multivalent liposomal vaccine compositions comprising polysaccharide antigens and a protein adjuvant |
| CA2655080A1 (en) | 2006-06-14 | 2007-12-21 | Macrogenics, Inc. | Methods for the treatment of autoimmune disorders using monoclonal antibodies with reduced toxicity |
| JP2010520874A (ja) * | 2007-03-09 | 2010-06-17 | メルク・シャープ・エンド・ドーム・コーポレイション | パピローマウイルスワクチン組成物 |
| DK2925297T3 (en) * | 2012-11-02 | 2017-10-02 | Cytuvax | COMPOSITION COMPREHENSIVE CYTOCHINE MACROAGGERATES |
| JP7478144B2 (ja) * | 2018-10-12 | 2024-05-02 | セラム インスティチュート オブ インディア プライベイト リミテッド | 低減用量の不活化ポリオウイルスを含む混合ワクチン組成物およびそれを調製するための方法 |
| WO2020102728A1 (en) | 2018-11-16 | 2020-05-22 | Neoimmunetech, Inc. | Method of treating a tumor with a combination of il-7 protein and an immune checkpoint inhibitor |
| US20230057939A1 (en) | 2020-01-13 | 2023-02-23 | Neoimmunetech, Inc. | Method of treating a tumor with a combination of il-7 protein and a bispecific antibody |
| US20230210952A1 (en) | 2020-02-05 | 2023-07-06 | Washington University | Method of treating a solid tumor with a combination of an il-7 protein and car-bearing immune cells |
| EP4232070A1 (de) | 2020-10-26 | 2023-08-30 | NeoImmuneTech, Inc. | Verfahren zur induktion von stammzellenmobilisierung |
| EP4236989A1 (de) | 2020-11-02 | 2023-09-06 | NeoImmuneTech, Inc. | Verwendung von interleukin-7 zur behandlung des coronavirus |
| EP4240408A1 (de) | 2020-11-05 | 2023-09-13 | Neoimmunetech, Inc. | Verfahren zur behandlung eines tumors mit einer kombination aus einem il-7-protein und einem nukleotidimpfstoff |
| AU2022283271A1 (en) | 2021-05-24 | 2023-12-07 | Provention Bio, Inc. | Methods for treating type 1 diabetes |
| US20250099542A1 (en) | 2021-12-30 | 2025-03-27 | Neoimmunetech, Inc. | Method of treating a tumor with a combination of il-7 protein and vegf antagonist |
| JP2026504619A (ja) | 2022-11-07 | 2026-02-06 | ネオイミューンテック, インコーポレイテッド | 非メチル化mgmtプロモーターを含む腫瘍を治療する方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2849632B2 (ja) * | 1988-04-08 | 1999-01-20 | 社団法人北里研究所 | ワクチン製剤 |
| DE3818054C2 (de) * | 1988-05-27 | 1994-02-17 | Biotest Pharma Gmbh | Verwendung einer Kombination aus einem Antigen bzw. einer Vakzine und humanem Interleukin zur Behandlung der Non-Responsiveness gegenüber immunologischen Defektzuständen |
| JPH0236129A (ja) * | 1988-07-22 | 1990-02-06 | Ajinomoto Co Inc | ワクチン効果増強剤 |
-
1990
- 1990-07-16 EP EP90911344A patent/EP0482076B1/de not_active Expired - Lifetime
- 1990-07-16 KR KR1019920700086A patent/KR0177179B1/ko not_active Expired - Fee Related
- 1990-07-16 DE DE69018990T patent/DE69018990T2/de not_active Expired - Fee Related
- 1990-07-16 DK DK90911344.1T patent/DK0482076T3/da active
- 1990-07-16 WO PCT/US1990/003982 patent/WO1991001143A1/en not_active Ceased
- 1990-07-16 ES ES90911344T patent/ES2075900T3/es not_active Expired - Lifetime
- 1990-07-16 AT AT90911344T patent/ATE121629T1/de not_active IP Right Cessation
- 1990-07-16 AU AU60500/90A patent/AU648509B2/en not_active Ceased
- 1990-07-16 CA CA002063587A patent/CA2063587C/en not_active Expired - Fee Related
- 1990-07-16 JP JP51060090A patent/JP3485184B2/ja not_active Expired - Fee Related
-
1992
- 1992-01-13 NO NO920161A patent/NO301577B1/no unknown
- 1992-01-13 FI FI920132A patent/FI104233B1/fi not_active IP Right Cessation
-
2003
- 2003-07-31 JP JP2003284148A patent/JP2004002463A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI920132A0 (fi) | 1992-01-13 |
| EP0482076B1 (de) | 1995-04-26 |
| WO1991001143A1 (en) | 1991-02-07 |
| NO920161D0 (no) | 1992-01-13 |
| ATE121629T1 (de) | 1995-05-15 |
| DK0482076T3 (da) | 1995-07-17 |
| FI104233B (fi) | 1999-12-15 |
| JP3485184B2 (ja) | 2004-01-13 |
| CA2063587C (en) | 2005-08-30 |
| KR0177179B1 (ko) | 1999-03-20 |
| DE69018990T2 (de) | 1995-12-14 |
| ES2075900T3 (es) | 1995-10-16 |
| AU6050090A (en) | 1991-02-22 |
| EP0482076A1 (de) | 1992-04-29 |
| AU648509B2 (en) | 1994-04-28 |
| DE69018990D1 (de) | 1995-06-01 |
| JP2004002463A (ja) | 2004-01-08 |
| JPH04506663A (ja) | 1992-11-19 |
| KR920703103A (ko) | 1992-12-17 |
| NO920161L (no) | 1992-03-05 |
| CA2063587A1 (en) | 1991-01-15 |
| NO301577B1 (no) | 1997-11-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or assigment of application |
Owner name: AMERICAN CYANAMID COMPANY |
|
| MA | Patent expired |