FR2284592A1 - Nouveaux derives de benzoxazole et procede pour leur preparation - Google Patents

Nouveaux derives de benzoxazole et procede pour leur preparation

Info

Publication number: FR2284592A1
Authority: FR; France
Prior art keywords: benzoxazole; preparation; new derivatives; derivatives; cyclising
Prior art date: 1972-05-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

FR7518361A

Other languages

English (en)

Other versions

FR2284592B1 (fr

Inventor

Delme Evans

David William Dunwell

Torence Alan Hicks

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Lilly Industries Ltd

Original Assignee

Lilly Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-05-18

Filing date

1975-06-12

Publication date

1976-04-09

1975-06-12 Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd

1976-04-09 Publication of FR2284592A1 publication Critical patent/FR2284592A1/fr

1979-01-05 Application granted granted Critical

1979-01-05 Publication of FR2284592B1 publication Critical patent/FR2284592B1/fr

Status Granted legal-status Critical Current

Links

BCMCBBGGLRIHSE-UHFFFAOYSA-N 1,3-benzoxazole Chemical class C1=CC=C2OC=NC2=C1 BCMCBBGGLRIHSE-UHFFFAOYSA-N 0.000 title abstract 2
CDAWCLOXVUBKRW-UHFFFAOYSA-N 2-aminophenol Chemical class NC1=CC=CC=C1O CDAWCLOXVUBKRW-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
-1 6-benzoxazolyl Chemical group 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
230000001760 anti-analgesic effect Effects 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
230000001754 anti-pyretic effect Effects 0.000 abstract 1
239000002221 antipyretic Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D263/57—Aryl or substituted aryl radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Rheumatology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Furan Compounds (AREA)

FR7518361A 1972-05-18 1975-06-12 Nouveaux derives de benzoxazole et procede pour leur preparation Granted FR2284592A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB2340972A GB1435721A (en)	1972-05-18	1972-05-18	Benzoxazole derivatives

Publications (2)

Publication Number	Publication Date
FR2284592A1 true FR2284592A1 (fr)	1976-04-09
FR2284592B1 FR2284592B1 (fr)	1979-01-05

Family

ID=10195157

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
FR7317894A Expired FR2184966B1 (fr)	1972-05-18	1973-05-17
FR7518361A Granted FR2284592A1 (fr)	1972-05-18	1975-06-12	Nouveaux derives de benzoxazole et procede pour leur preparation

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
FR7317894A Expired FR2184966B1 (fr)	1972-05-18	1973-05-17

Country Status (31)

Country	Link
US (1)	US3912748A (fr)
JP (6)	JPS5912672B2 (fr)
KR (1)	KR780000234B1 (fr)
AR (4)	AR230991A1 (fr)
AT (1)	AT333752B (fr)
BE (1)	BE799790A (fr)
BG (1)	BG21408A3 (fr)
CA (1)	CA1029019A (fr)
CH (5)	CH595361A5 (fr)
CS (1)	CS200455B2 (fr)
CY (1)	CY1016A (fr)
DD (1)	DD105229A5 (fr)
DE (1)	DE2324443A1 (fr)
DK (1)	DK140340B (fr)
ES (1)	ES414863A1 (fr)
FR (2)	FR2184966B1 (fr)
GB (1)	GB1435721A (fr)
HK (1)	HK72579A (fr)
HU (1)	HU167933B (fr)
IE (2)	IE37564B1 (fr)
IL (2)	IL42102A (fr)
KE (1)	KE2975A (fr)
MY (1)	MY8000063A (fr)
NL (1)	NL170145C (fr)
PH (3)	PH9685A (fr)
PL (3)	PL94208B1 (fr)
RO (2)	RO66800A (fr)
SE (3)	SE386174B (fr)
SU (3)	SU574157A3 (fr)
YU (3)	YU130473A (fr)
ZA (1)	ZA732791B (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1495488A (en) *	1976-06-23	1977-12-21	Ippco Int Pharma Patents Co Es	Optically active 2-(2-phenyl-5-benzoxazolyl)propionic acids
US4087437A (en) *	1976-09-07	1978-05-02	Eli Lilly And Company	2-Phenyl-5-benzoxazolylalkanoic acid purification process
GB1590587A (en) *	1977-06-28	1981-06-03	Lilly Industries Ltd	Benoxaprofen
IT1099589B (it) *	1978-08-04	1985-09-18	Ravizza Spa	Processo per la preparazione di derivati dell'acido benzoxazolil propionico
CA1125768A (fr) *	1978-10-31	1982-06-15	Hoffmann-La Roche Limited	Derives de benzoxazole
GR75153B (fr) *	1981-03-27	1984-07-13	Lilly Co Eli
IT1157295B (it) *	1982-07-19	1987-02-11	Ravizza Spa	Processo perfezionato per la preparazione di derivati dell'acido benzoxazolil propionico
DE3413875A1 (de) *	1984-04-12	1985-10-17	Ludwig Heumann & Co GmbH, 8500 Nürnberg	Benzothiazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltendes arzneimittel
IT1177017B (it) *	1984-10-22	1987-08-26	Ravizza Spa	Processo per la preparazione dell'acido 2(4-flurofenil)alfa-metil-5-benzox azoloacetico
US4873259A (en) *	1987-06-10	1989-10-10	Abbott Laboratories	Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds
US4822809A (en) *	1987-11-13	1989-04-18	Abbott Laboratories	Benzazole lipoxygenase inhibiting compounds
IT1233836B (it) *	1988-01-13	1992-04-21	Euroresearch Srl	Sali idrosolubili dell'acido (+)2-(4 fluorofenil)-alfa-metil-5 benzoxazolo acetato.
UA83620C2 (ru) *	2001-12-05	2008-08-11	Уайт	Замещенные бензоксазолы и их аналоги как эстрогенные агенты
AU2003283597A1 (en) *	2002-11-16	2004-06-15	Oxford Glycosciences (Uk) Ltd	Benzoxazole, benzthiazole and benzimidazole acid derivatives and their use as heparanase inhibitors
EP1599449A2 (fr) *	2003-02-25	2005-11-30	TopoTarget UK Limited	Composes d'acide carbamique comprenant un groupe heteroaryle bicyclique utilises en tant qu'inhibiteurs de hdac
KR101291483B1 (ko) *	2004-12-15	2013-07-30	돔페 파르마 에스.피.에이.	2-아릴프로피온산 유도체 및 이들을 함유하는 제약학적조성물
AU2006249866B2 (en)	2005-05-26	2011-10-13	Aldeyra Therapeutics, Inc.	Compositions and methods of treating retinal disease
JP5369854B2 (ja)	2008-04-21	2013-12-18	住友化学株式会社	有害節足動物防除組成物および縮合複素環化合物
CA2782015C (fr)	2009-12-11	2020-08-25	Neuron Systems, Inc.	Compositions ophthalmiques topiques et methodes de traitement de la degenerescence maculaire
CN111135171B (zh)	2013-01-23	2023-09-08	奥尔德拉医疗公司	与毒性醛相关的疾病和治疗
AU2014209585A1 (en)	2013-01-25	2015-07-23	Aldeyra Therapeutics, Inc.	Novel traps in the treatment of macular degeneration
US20170298081A1 (en) *	2014-08-08	2017-10-19	Kasuma Partners Inc.	Condensed heterocyclic compound
CN118724806A (zh)	2015-08-21	2024-10-01	奥尔德拉医疗公司	氘化化合物和其用途
CN109152774A (zh)	2016-05-09	2019-01-04	奥尔德拉医疗公司	眼部炎性病症和疾病的组合治疗
WO2018170476A1 (fr)	2017-03-16	2018-09-20	Aldeyra Therapeutics, Inc.	Composés polymorphes et leurs utilisations
CN111356451A (zh)	2017-10-10	2020-06-30	奥尔德拉医疗公司	炎性病症的治疗
CN112714762A (zh)	2018-08-06	2021-04-27	奥尔德拉医疗公司	多晶型化合物及其用途
CN113056353B (zh)	2018-09-25	2022-11-01	奥尔德拉医疗公司	用于治疗干眼病的调配物
US11786518B2 (en)	2019-03-26	2023-10-17	Aldeyra Therapeutics, Inc.	Ophthalmic formulations and uses thereof
US12098132B2 (en)	2019-05-02	2024-09-24	Aldeyra Therapeutics, Inc.	Process for preparation of aldehyde scavenger and intermediates
CN113784954A (zh)	2019-05-02	2021-12-10	奥尔德拉医疗公司	多晶型化合物和其用途
WO2021231792A1 (fr)	2020-05-13	2021-11-18	Aldeyra Therapeutics, Inc.	Formulations pharmaceutiques et leurs utilisations

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee
FR2037486A5 (fr) *	1969-03-03	1970-12-31	Ciba Geigy
FR2132372A1 (fr) *	1971-04-01	1972-11-17	Boehringer Sohn Ingelheim
FR2248039A1 (fr) *	1973-10-23	1975-05-16	Lilly Industries Ltd

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DD70860A (fr) *
BE625278A (fr) *	1961-11-27
DE2118315C3 (de) *	1970-04-20	1975-04-03	Sumitomo Chemical Co., Ltd., Osaka (Japan)	2-(1H)-Chinazolinonderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
IL37633A (en) *	1970-09-10	1975-08-31	Merck & Co Inc	2-(4-(2-benzoxazolyl)phenyl)alkanoic acid derivatives
GB1590587A (en) *	1977-06-28	1981-06-03	Lilly Industries Ltd	Benoxaprofen

1972
- 1972-05-18 GB GB2340972A patent/GB1435721A/en not_active Expired
1973
- 1973-04-25 ZA ZA732791A patent/ZA732791B/xx unknown
- 1973-04-25 IL IL42102A patent/IL42102A/en unknown
- 1973-04-25 IE IE1898/76A patent/IE37564B1/xx unknown
- 1973-04-28 IE IE648/73A patent/IE37563B1/xx unknown
- 1973-05-01 CA CA170,186A patent/CA1029019A/fr not_active Expired
- 1973-05-01 US US356251A patent/US3912748A/en not_active Expired - Lifetime
- 1973-05-07 PH PH14592*UA patent/PH9685A/en unknown
- 1973-05-11 AR AR247979A patent/AR230991A1/es active
- 1973-05-15 DE DE2324443A patent/DE2324443A1/de not_active Ceased
- 1973-05-15 CY CY1016A patent/CY1016A/xx unknown
- 1973-05-16 HU HULI244A patent/HU167933B/hu not_active IP Right Cessation
- 1973-05-16 KR KR7300790A patent/KR780000234B1/ko not_active Expired
- 1973-05-16 CS CS733508A patent/CS200455B2/cs unknown
- 1973-05-16 DD DD170872A patent/DD105229A5/xx unknown
- 1973-05-17 CH CH1621275A patent/CH595361A5/xx not_active IP Right Cessation
- 1973-05-17 AT AT432573A patent/AT333752B/de not_active IP Right Cessation
- 1973-05-17 ES ES414863A patent/ES414863A1/es not_active Expired
- 1973-05-17 JP JP48055110A patent/JPS5912672B2/ja not_active Expired
- 1973-05-17 CH CH703673A patent/CH592071A5/xx not_active IP Right Cessation
- 1973-05-17 SE SE7307005A patent/SE386174B/xx unknown
- 1973-05-17 CH CH1621375A patent/CH587834A5/xx not_active IP Right Cessation
- 1973-05-17 CH CH1298676A patent/CH594643A5/xx not_active IP Right Cessation
- 1973-05-17 FR FR7317894A patent/FR2184966B1/fr not_active Expired
- 1973-05-17 CH CH1298576A patent/CH595362A5/xx not_active IP Right Cessation
- 1973-05-17 DK DK274673AA patent/DK140340B/da not_active IP Right Cessation
- 1973-05-17 YU YU01304/73A patent/YU130473A/xx unknown
- 1973-05-17 SU SU7301916802A patent/SU574157A3/ru active
- 1973-05-18 PL PL1973183011A patent/PL94208B1/pl unknown
- 1973-05-18 RO RO7384621A patent/RO66800A/fr unknown
- 1973-05-18 NL NLAANVRAGE7307018,A patent/NL170145C/xx not_active IP Right Cessation
- 1973-05-18 BE BE6044169A patent/BE799790A/fr not_active IP Right Cessation
- 1973-05-18 PL PL1973162653A patent/PL89247B1/pl unknown
- 1973-05-18 RO RO7374829A patent/RO66278A/fr unknown
- 1973-05-18 PL PL1973182614A patent/PL92565B1/pl unknown
- 1973-05-18 BG BG023657A patent/BG21408A3/xx unknown
1974
- 1974-11-21 PH PH16541A patent/PH11718A/en unknown
- 1974-11-21 PH PH16542A patent/PH10704A/en unknown
- 1974-11-29 SU SU7402079274A patent/SU580837A3/ru active
- 1974-11-29 SU SU7402079273A patent/SU582762A3/ru active
1975
- 1975-01-01 AR AR257862A patent/AR207857A1/es active
- 1975-01-01 AR AR257863A patent/AR205021A1/es active
- 1975-06-12 FR FR7518361A patent/FR2284592A1/fr active Granted
- 1975-08-22 SE SE7509387A patent/SE434399B/xx not_active IP Right Cessation
- 1975-12-23 IL IL48711A patent/IL48711A0/xx unknown
1976
- 1976-03-06 AR AR257861A patent/AR212010A1/es active
1977
- 1977-09-21 SE SE7710602A patent/SE435838B/xx not_active IP Right Cessation
1979
- 1979-05-17 YU YU1171/79A patent/YU36298B/xx unknown
- 1979-05-17 YU YU01170/79A patent/YU117079A/xx unknown
- 1979-07-03 KE KE2975A patent/KE2975A/xx unknown
- 1979-10-11 HK HK725/79A patent/HK72579A/xx unknown
1980
- 1980-12-31 MY MY198063A patent/MY8000063A/xx unknown
1981
- 1981-05-13 JP JP56072123A patent/JPS5929185B2/ja not_active Expired
- 1981-05-13 JP JP7212281A patent/JPS56167674A/ja active Pending
- 1981-05-13 JP JP7212481A patent/JPS56167675A/ja active Pending
- 1981-05-13 JP JP7212181A patent/JPS56167673A/ja active Pending
1984
- 1984-02-02 JP JP59017637A patent/JPS6021976B2/ja not_active Expired

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee
FR2037486A5 (fr) *	1969-03-03	1970-12-31	Ciba Geigy
FR2132372A1 (fr) *	1971-04-01	1972-11-17	Boehringer Sohn Ingelheim
FR2248039A1 (fr) *	1973-10-23	1975-05-16	Lilly Industries Ltd

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
("J.HETEROCYCLIC CHEM." 1972 9 3 P.681-682.) *
J.HETEROCYCLIC CHEM." 1972 9 3 P.681-682.) *

Also Published As

Publication number	Publication date
RO66278A (fr)	1981-06-26
MY8000063A (en)	1980-12-31
SE435838B (sv)	1984-10-22
JPS56167645A (en)	1981-12-23
ATA432573A (de)	1976-04-15
RO66800A (fr)	1982-03-24
YU117079A (en)	1981-08-31
IE37564B1 (en)	1977-08-17
CA1029019A (fr)	1978-04-04
PL89247B1 (fr)	1976-11-30
JPS59161346A (ja)	1984-09-12
NL170145B (nl)	1982-05-03
ES414863A1 (es)	1976-02-01
SE386174B (sv)	1976-08-02
FR2184966A1 (fr)	1973-12-28
IE37564L (en)	1973-11-18
IL42102A0 (en)	1973-06-29
KE2975A (en)	1979-07-20
CS200455B2 (en)	1980-09-15
CH595361A5 (fr)	1978-02-15
DK140340B (da)	1979-08-06
HU167933B (fr)	1976-01-28
YU36298B (en)	1982-06-18
IL42102A (en)	1977-07-31
JPS56167674A (en)	1981-12-23
JPS56167675A (en)	1981-12-23
FR2284592B1 (fr)	1979-01-05
SU582762A3 (ru)	1977-11-30
SE7710602L (sv)	1977-09-21
JPS6021976B2 (ja)	1985-05-30
SE7509387L (sv)	1975-08-22
AT333752B (de)	1976-12-10
SE434399B (sv)	1984-07-23
NL170145C (nl)	1982-10-01
PH10704A (en)	1977-08-24
US3912748A (en)	1975-10-14
PH11718A (en)	1978-05-30
YU117179A (en)	1981-08-31
JPS4954363A (fr)	1974-05-27
AU5590773A (en)	1974-11-21
ZA732791B (en)	1974-12-24
CH592071A5 (fr)	1977-10-14
GB1435721A (en)	1976-05-12
PL92565B1 (fr)	1977-04-30
PH9685A (en)	1976-02-10
AR230991A1 (es)	1984-08-31
DK140340C (fr)	1979-12-31
CH587834A5 (fr)	1977-05-13
IE37563L (en)	1973-11-18
IL48711A0 (en)	1976-02-29
AR207857A1 (es)	1976-11-08
CH594643A5 (fr)	1978-01-13
JPS5929185B2 (ja)	1984-07-18
IE37563B1 (en)	1977-08-17
JPS5912672B2 (ja)	1984-03-24
SU574157A3 (ru)	1977-09-25
HK72579A (en)	1979-10-19
JPS56167673A (en)	1981-12-23
AR212010A1 (es)	1978-04-28
CY1016A (en)	1979-11-23
DE2324443A1 (de)	1973-11-29
SU580837A3 (ru)	1977-11-15
DD105229A5 (fr)	1974-04-12
BG21408A3 (bg)	1976-05-20
YU130473A (en)	1981-08-31
BE799790A (fr)	1973-11-19
FR2184966B1 (fr)	1979-01-12
PL94208B1 (fr)	1977-07-30
AR205021A1 (es)	1976-03-31
KR780000234B1 (en)	1978-07-01
NL7307018A (fr)	1973-11-20
CH595362A5 (fr)	1978-02-15

Legal Events

Date	Code	Title
1976-07-23	AR	Application made for restoration
1976-09-03	AR	Application made for restoration
1993-03-26	ST	Notification of lapse

Publication	Publication Date	Title
SE386174B (sv)	1976-08-02	Forfarande for framstellning av bensoxazolderivat.
OA03907A (fr)	1975-08-14	Procédé de préparation de nouveaux dérivés de l'isoindoline.
RO62810A (fr)	1978-01-15	Procede pour la preparation des acides hydroxydiphenylylpropioniques
BE816973A (fr)	1974-12-27	Procede de preparation de l'0,o-diethyldithio-phosphorylmethyl-3 chloro-6 benzoxazolone
CH457423A (fr)	1968-06-15	Procédé de préparation de nouveaux dérivés de la série de l'estrane
OA03393A (fr)	1970-12-15	Procédé pour la préparation de nouveaux acides gras B-phénylés.
OA04342A (fr)	1980-01-31	Procédé de préparation de nouveaux dérivés de salicylanilide.
CH554353A (fr)	1974-09-30	Procede de preparation de nouveaux derives de l'isoindoline.
OA04368A (fr)	1980-01-31	Procédé de préparation de nouveaux acylamino acides.
RO62639A (fr)	1978-05-15	Procede pour la preparation des acides 2-alcoxy-inferieur-5-alkyle-inferieur-
CH518253A (fr)	1972-01-31	Procédé de préparation de nouveaux acides cyclohexényl acétiques
BE808187A (fr)	1974-06-04	Procede de preparation d'halogenures d'acides halogenomethyl-phosphoniques
BE805999A (fr)	1974-04-12	Procede de preparation d'ethers en 4 d'acides 3-amino-5- sulfamoyl-benzoiques
OA03550A (fr)	1971-03-30	Procédé pour la préparation de nouveaux acides carboxiliques.
BE808247A (fr)	1974-06-05	Procede de preparation de dihalogenures d'acides halogenomethane-phosphoniques
BE795721A (fr)	1973-08-21	Procede de preparation d'acides omega- ureidocarboxyliques
RO62549A2 (fr)	1978-02-15	Procede pour la preparation du ethyl 1/-cyclohexenylecynacetat de methyle