JPS56167675A - Manufacture of benzoxazole derivative - Google Patents

Manufacture of benzoxazole derivative

Info

Publication number: JPS56167675A
Authority: JP; Japan
Prior art keywords: manufacture; benzoxazole derivative; benzoxazole; cyclising; pyretic
Prior art date: 1972-05-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP7212481A

Other languages

English (en)

Inventor

Ebuansu Derumu

Uiriamu Danuiru Debuitsuto

Aran Hitsukusu Terensu

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Lilly Industries Ltd

Original Assignee

Lilly Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-05-18

Filing date

1981-05-13

Publication date

1981-12-23

1981-05-13 Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd

1981-12-23 Publication of JPS56167675A publication Critical patent/JPS56167675A/ja

Status Pending legal-status Critical Current

Links

BCMCBBGGLRIHSE-UHFFFAOYSA-N 1,3-benzoxazole Chemical class C1=CC=C2OC=NC2=C1 BCMCBBGGLRIHSE-UHFFFAOYSA-N 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title abstract 2
CDAWCLOXVUBKRW-UHFFFAOYSA-N 2-aminophenol Chemical class NC1=CC=CC=C1O CDAWCLOXVUBKRW-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
-1 6-benzoxazolyl Chemical group 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
230000001760 anti-analgesic effect Effects 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
230000001754 anti-pyretic effect Effects 0.000 abstract 1
239000002221 antipyretic Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D263/57—Aryl or substituted aryl radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Furan Compounds (AREA)

JP7212481A 1972-05-18 1981-05-13 Manufacture of benzoxazole derivative Pending JPS56167675A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB2340972A GB1435721A (en)	1972-05-18	1972-05-18	Benzoxazole derivatives

Publications (1)

Publication Number	Publication Date
JPS56167675A true JPS56167675A (en)	1981-12-23

Family

ID=10195157

Family Applications (6)

Application Number	Title	Priority Date	Filing Date
JP48055110A Expired JPS5912672B2 (ja)	1972-05-18	1973-05-17	ベンゾオキサゾ−ル誘導体の製造法
JP7212481A Pending JPS56167675A (en)	1972-05-18	1981-05-13	Manufacture of benzoxazole derivative
JP7212281A Pending JPS56167674A (en)	1972-05-18	1981-05-13	Manufacture of benzoxazole derivative
JP7212181A Pending JPS56167673A (en)	1972-05-18	1981-05-13	Manufacture of benzoxazole derivative
JP56072123A Expired JPS5929185B2 (ja)	1972-05-18	1981-05-13	フエノ−ル誘導体の製造法
JP59017637A Expired JPS6021976B2 (ja)	1972-05-18	1984-02-02	フエノール誘導体の製造法

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
JP48055110A Expired JPS5912672B2 (ja)	1972-05-18	1973-05-17	ベンゾオキサゾ−ル誘導体の製造法

Family Applications After (4)

Application Number	Title	Priority Date	Filing Date
JP7212281A Pending JPS56167674A (en)	1972-05-18	1981-05-13	Manufacture of benzoxazole derivative
JP7212181A Pending JPS56167673A (en)	1972-05-18	1981-05-13	Manufacture of benzoxazole derivative
JP56072123A Expired JPS5929185B2 (ja)	1972-05-18	1981-05-13	フエノ−ル誘導体の製造法
JP59017637A Expired JPS6021976B2 (ja)	1972-05-18	1984-02-02	フエノール誘導体の製造法

Country Status (31)

Country	Link
US (1)	US3912748A (ja)
JP (6)	JPS5912672B2 (ja)
KR (1)	KR780000234B1 (ja)
AR (4)	AR230991A1 (ja)
AT (1)	AT333752B (ja)
BE (1)	BE799790A (ja)
BG (1)	BG21408A3 (ja)
CA (1)	CA1029019A (ja)
CH (5)	CH595361A5 (ja)
CS (1)	CS200455B2 (ja)
CY (1)	CY1016A (ja)
DD (1)	DD105229A5 (ja)
DE (1)	DE2324443A1 (ja)
DK (1)	DK140340B (ja)
ES (1)	ES414863A1 (ja)
FR (2)	FR2184966B1 (ja)
GB (1)	GB1435721A (ja)
HK (1)	HK72579A (ja)
HU (1)	HU167933B (ja)
IE (2)	IE37564B1 (ja)
IL (2)	IL42102A (ja)
KE (1)	KE2975A (ja)
MY (1)	MY8000063A (ja)
NL (1)	NL170145C (ja)
PH (3)	PH9685A (ja)
PL (3)	PL89247B1 (ja)
RO (2)	RO66800A (ja)
SE (3)	SE386174B (ja)
SU (3)	SU574157A3 (ja)
YU (3)	YU130473A (ja)
ZA (1)	ZA732791B (ja)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1495488A (en) *	1976-06-23	1977-12-21	Ippco Int Pharma Patents Co Es	Optically active 2-(2-phenyl-5-benzoxazolyl)propionic acids
US4087437A (en) *	1976-09-07	1978-05-02	Eli Lilly And Company	2-Phenyl-5-benzoxazolylalkanoic acid purification process
GB1590587A (en) *	1977-06-28	1981-06-03	Lilly Industries Ltd	Benoxaprofen
IT1099589B (it) *	1978-08-04	1985-09-18	Ravizza Spa	Processo per la preparazione di derivati dell'acido benzoxazolil propionico
CA1125768A (en) *	1978-10-31	1982-06-15	Hoffmann-La Roche Limited	Benzoxazole derivatives
GR75153B (ja) *	1981-03-27	1984-07-13	Lilly Co Eli
IT1157295B (it) *	1982-07-19	1987-02-11	Ravizza Spa	Processo perfezionato per la preparazione di derivati dell'acido benzoxazolil propionico
DE3413875A1 (de) *	1984-04-12	1985-10-17	Ludwig Heumann & Co GmbH, 8500 Nürnberg	Benzothiazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltendes arzneimittel
IT1177017B (it) *	1984-10-22	1987-08-26	Ravizza Spa	Processo per la preparazione dell'acido 2(4-flurofenil)alfa-metil-5-benzox azoloacetico
US4873259A (en) *	1987-06-10	1989-10-10	Abbott Laboratories	Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds
US4822809A (en) *	1987-11-13	1989-04-18	Abbott Laboratories	Benzazole lipoxygenase inhibiting compounds
IT1233836B (it) *	1988-01-13	1992-04-21	Euroresearch Srl	Sali idrosolubili dell'acido (+)2-(4 fluorofenil)-alfa-metil-5 benzoxazolo acetato.
UA83620C2 (ru) *	2001-12-05	2008-08-11	Уайт	Замещенные бензоксазолы и их аналоги как эстрогенные агенты
WO2004046122A2 (en) *	2002-11-16	2004-06-03	Oxford Glycosciences (Uk) Ltd	Benzoxazole, benzthiazole and benzimidazole acid derivatives and their use as heparanase inhibitors
WO2004076386A2 (en)	2003-02-25	2004-09-10	Topotarget Uk Limited	Carbamic acid compounds comprising a bicyclic heteroaryl group as hdac inhibitors
NZ555502A (en) *	2004-12-15	2010-12-24	Dompe Pha R Ma Spa Res & Mfg	2-arylpropionic acid derivatives and pharmaceutical compositions containing them
EP2336117A1 (en)	2005-05-26	2011-06-22	Neuron Systems, Inc	Heterocyclic compounds for treating retinal diseases
JP5369854B2 (ja)	2008-04-21	2013-12-18	住友化学株式会社	有害節足動物防除組成物および縮合複素環化合物
WO2011072141A1 (en)	2009-12-11	2011-06-16	Neuron Systems, Inc.	Compositions and methods for the treatment of macular degeneration
CA2898631C (en)	2013-01-23	2023-06-13	Aldeyra Therapeutics, Inc.	Toxic aldehyde related diseases and treatment
HK1217490A1 (zh)	2013-01-25	2017-01-13	Aldeyra Therapeutics, Inc.	黃斑變性治療中的新穎捕獲劑
WO2016021706A1 (ja) *	2014-08-08	2016-02-11	カズマパートナーズ株式会社	縮合複素環化合物
CN108135907A (zh)	2015-08-21	2018-06-08	奥尔德拉医疗公司	氘化化合物和其用途
US11129823B2 (en)	2016-05-09	2021-09-28	Aldeyra Therapeutics, Inc.	Combination treatment of ocular inflammatory disorders and diseases
US10414732B2 (en)	2017-03-16	2019-09-17	Aldeyra Therapeutics, Inc.	Polymorphic compounds and uses thereof
MX2020003425A (es)	2017-10-10	2020-07-29	Aldeyra Therapeutics Inc	Tratamiento de trastornos inflamatorios.
EP3833660A4 (en)	2018-08-06	2022-05-11	Aldeyra Therapeutics, Inc.	POLYMORPHIC COMPOUNDS AND THEIR USES
JP7505786B2 (ja)	2018-09-25	2024-06-25	アルデイラセラピューティクス，インコーポレイテッド	ドライアイ疾患を処置するための製剤
WO2020198064A1 (en)	2019-03-26	2020-10-01	Aldeyra Therapeutics, Inc.	Ophthalmic formulations and uses thereof
CA3137301A1 (en)	2019-05-02	2020-11-05	Aldeyra Therapeutics, Inc.	Polymorphic compounds and uses thereof
US12098132B2 (en)	2019-05-02	2024-09-24	Aldeyra Therapeutics, Inc.	Process for preparation of aldehyde scavenger and intermediates
WO2021231792A1 (en)	2020-05-13	2021-11-18	Aldeyra Therapeutics, Inc.	Pharmaceutical formulations and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DD70860A (ja) *
NL285932A (ja) *	1961-11-27
CH516339A (de) *	1969-03-03	1971-12-15	Ciba Geigy Ag	Verwendung von Azolverbindungen als Antioxydantien
DE2118315C3 (de) *	1970-04-20	1975-04-03	Sumitomo Chemical Co., Ltd., Osaka (Japan)	2-(1H)-Chinazolinonderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
IL37633A (en) *	1970-09-10	1975-08-31	Merck & Co Inc	2-(4-(2-benzoxazolyl)phenyl)alkanoic acid derivatives
DE2115926C3 (de) *	1971-04-01	1978-05-03	C.H. Boehringer Sohn, 6507 Ingelheim	1 -(4-Hydroxy-3-dimethylaminosuIfamidophenyI)-2-aminoäthanderivate, Verfahren zu ihrer Herstellung und diese enthaltende Mittel
GB1491863A (en) *	1973-10-23	1977-11-16	Lilly Industries Ltd	2,5-or 2,6-disubstituted benzoxazoles
GB1590587A (en) *	1977-06-28	1981-06-03	Lilly Industries Ltd	Benoxaprofen

1972
- 1972-05-18 GB GB2340972A patent/GB1435721A/en not_active Expired
1973
- 1973-04-25 ZA ZA732791A patent/ZA732791B/xx unknown
- 1973-04-25 IL IL42102A patent/IL42102A/en unknown
- 1973-04-25 IE IE1898/76A patent/IE37564B1/xx unknown
- 1973-04-28 IE IE648/73A patent/IE37563B1/xx unknown
- 1973-05-01 CA CA170,186A patent/CA1029019A/en not_active Expired
- 1973-05-01 US US356251A patent/US3912748A/en not_active Expired - Lifetime
- 1973-05-07 PH PH14592*UA patent/PH9685A/en unknown
- 1973-05-11 AR AR247979A patent/AR230991A1/es active
- 1973-05-15 DE DE2324443A patent/DE2324443A1/de not_active Ceased
- 1973-05-15 CY CY1016A patent/CY1016A/xx unknown
- 1973-05-16 KR KR7300790A patent/KR780000234B1/ko not_active Expired
- 1973-05-16 HU HULI244A patent/HU167933B/hu not_active IP Right Cessation
- 1973-05-16 DD DD170872A patent/DD105229A5/xx unknown
- 1973-05-16 CS CS733508A patent/CS200455B2/cs unknown
- 1973-05-17 CH CH1621275A patent/CH595361A5/xx not_active IP Right Cessation
- 1973-05-17 SU SU7301916802A patent/SU574157A3/ru active
- 1973-05-17 DK DK274673AA patent/DK140340B/da not_active IP Right Cessation
- 1973-05-17 AT AT432573A patent/AT333752B/de not_active IP Right Cessation
- 1973-05-17 CH CH1298576A patent/CH595362A5/xx not_active IP Right Cessation
- 1973-05-17 FR FR7317894A patent/FR2184966B1/fr not_active Expired
- 1973-05-17 CH CH1621375A patent/CH587834A5/xx not_active IP Right Cessation
- 1973-05-17 CH CH703673A patent/CH592071A5/xx not_active IP Right Cessation
- 1973-05-17 YU YU01304/73A patent/YU130473A/xx unknown
- 1973-05-17 JP JP48055110A patent/JPS5912672B2/ja not_active Expired
- 1973-05-17 CH CH1298676A patent/CH594643A5/xx not_active IP Right Cessation
- 1973-05-17 SE SE7307005A patent/SE386174B/xx unknown
- 1973-05-17 ES ES414863A patent/ES414863A1/es not_active Expired
- 1973-05-18 RO RO7384621A patent/RO66800A/ro unknown
- 1973-05-18 PL PL1973162653A patent/PL89247B1/pl unknown
- 1973-05-18 PL PL1973183011A patent/PL94208B1/pl unknown
- 1973-05-18 BG BG023657A patent/BG21408A3/xx unknown
- 1973-05-18 PL PL1973182614A patent/PL92565B1/pl unknown
- 1973-05-18 RO RO7374829A patent/RO66278A/ro unknown
- 1973-05-18 BE BE6044169A patent/BE799790A/xx not_active IP Right Cessation
- 1973-05-18 NL NLAANVRAGE7307018,A patent/NL170145C/xx not_active IP Right Cessation
1974
- 1974-11-21 PH PH16542A patent/PH10704A/en unknown
- 1974-11-21 PH PH16541A patent/PH11718A/en unknown
- 1974-11-29 SU SU7402079273A patent/SU582762A3/ru active
- 1974-11-29 SU SU7402079274A patent/SU580837A3/ru active
1975
- 1975-01-01 AR AR257862A patent/AR207857A1/es active
- 1975-01-01 AR AR257863A patent/AR205021A1/es active
- 1975-06-12 FR FR7518361A patent/FR2284592A1/fr active Granted
- 1975-08-22 SE SE7509387A patent/SE434399B/xx not_active IP Right Cessation
- 1975-12-23 IL IL48711A patent/IL48711A0/xx unknown
1976
- 1976-03-06 AR AR257861A patent/AR212010A1/es active
1977
- 1977-09-21 SE SE7710602A patent/SE435838B/xx not_active IP Right Cessation
1979
- 1979-05-17 YU YU01170/79A patent/YU117079A/xx unknown
- 1979-05-17 YU YU1171/79A patent/YU36298B/xx unknown
- 1979-07-03 KE KE2975A patent/KE2975A/xx unknown
- 1979-10-11 HK HK725/79A patent/HK72579A/xx unknown
1980
- 1980-12-31 MY MY198063A patent/MY8000063A/xx unknown
1981
- 1981-05-13 JP JP7212481A patent/JPS56167675A/ja active Pending
- 1981-05-13 JP JP7212281A patent/JPS56167674A/ja active Pending
- 1981-05-13 JP JP7212181A patent/JPS56167673A/ja active Pending
- 1981-05-13 JP JP56072123A patent/JPS5929185B2/ja not_active Expired
1984
- 1984-02-02 JP JP59017637A patent/JPS6021976B2/ja not_active Expired

Also Published As

Publication number	Publication date
IE37564B1 (en)	1977-08-17
JPS56167674A (en)	1981-12-23
YU117079A (en)	1981-08-31
AT333752B (de)	1976-12-10
AU5590773A (en)	1974-11-21
YU36298B (en)	1982-06-18
PL92565B1 (ja)	1977-04-30
SE7710602L (sv)	1977-09-21
PH11718A (en)	1978-05-30
RO66278A (ro)	1981-06-26
YU117179A (en)	1981-08-31
CH587834A5 (ja)	1977-05-13
RO66800A (ro)	1982-03-24
JPS4954363A (ja)	1974-05-27
PL94208B1 (ja)	1977-07-30
BE799790A (fr)	1973-11-19
GB1435721A (en)	1976-05-12
IL42102A (en)	1977-07-31
FR2184966B1 (ja)	1979-01-12
SE386174B (sv)	1976-08-02
FR2284592B1 (ja)	1979-01-05
CS200455B2 (en)	1980-09-15
JPS5912672B2 (ja)	1984-03-24
JPS56167673A (en)	1981-12-23
AR207857A1 (es)	1976-11-08
DK140340B (da)	1979-08-06
CA1029019A (en)	1978-04-04
JPS5929185B2 (ja)	1984-07-18
KR780000234B1 (en)	1978-07-01
AR205021A1 (es)	1976-03-31
PH10704A (en)	1977-08-24
US3912748A (en)	1975-10-14
ATA432573A (de)	1976-04-15
IL42102A0 (en)	1973-06-29
DE2324443A1 (de)	1973-11-29
YU130473A (en)	1981-08-31
ZA732791B (en)	1974-12-24
AR230991A1 (es)	1984-08-31
IE37563B1 (en)	1977-08-17
SE434399B (sv)	1984-07-23
JPS56167645A (en)	1981-12-23
AR212010A1 (es)	1978-04-28
SU582762A3 (ru)	1977-11-30
HU167933B (ja)	1976-01-28
SU580837A3 (ru)	1977-11-15
CY1016A (en)	1979-11-23
SE7509387L (sv)	1975-08-22
PL89247B1 (ja)	1976-11-30
ES414863A1 (es)	1976-02-01
SU574157A3 (ru)	1977-09-25
FR2284592A1 (fr)	1976-04-09
MY8000063A (en)	1980-12-31
HK72579A (en)	1979-10-19
CH595361A5 (ja)	1978-02-15
BG21408A3 (bg)	1976-05-20
FR2184966A1 (ja)	1973-12-28
DK140340C (ja)	1979-12-31
NL170145C (nl)	1982-10-01
DD105229A5 (ja)	1974-04-12
NL7307018A (ja)	1973-11-20
PH9685A (en)	1976-02-10
JPS6021976B2 (ja)	1985-05-30
CH594643A5 (ja)	1978-01-13
IL48711A0 (en)	1976-02-29
IE37563L (en)	1973-11-18
JPS59161346A (ja)	1984-09-12
KE2975A (en)	1979-07-20
CH592071A5 (ja)	1977-10-14
NL170145B (nl)	1982-05-03
IE37564L (en)	1973-11-18
SE435838B (sv)	1984-10-22
CH595362A5 (ja)	1978-02-15

Publication	Publication Date	Title
JPS56167673A (en)	1981-12-23	Manufacture of benzoxazole derivative
OA04406A (fr)	1980-02-29	Procédé de préparation de dérivés de 14-hydroxy-morphinane.
ES412813A1 (es)	1976-07-01	Un procedimiento de preparacion de derivados de 1,2-benzoi-soxazol 3-sustituidos.
OA04555A (fr)	1980-04-30	Procédé de préparation de dérivés de benzofuranne.
BG49615A3 (bg)	1991-12-16	Метод за получаване на производни на 3-заместени тиометилцефало- спорини или техни етилови, или дифенилетилови естери, или техни соли
OA04655A (fr)	1980-12-31	Procédé de production de dérivés 3-thiolés d'acides 7-acylamidocéphalosporanique.
ES432334A1 (es)	1976-11-01	Procedimiento de obtencion de derivados 1-amido alquil-4- sulfonil-piperazina.
ES414645A1 (es)	1976-06-16	Un procedimiento para convertir un penilinsufoxido en una desacetoxi-cefalosporina.
SE427276B (sv)	1983-03-21	Forfarande for framstellning av d-homosteroider
GB1122135A (en)	1968-07-31	A new derivative of 4-hydroxy-coumarin, process for preparing same, and applications thereof
FR1247320A (fr)	1960-12-02	Procédé de préparation des dérivés de l'aldéhyde de la vitamine a
ES399544A3 (es)	1974-11-16	Un procedimiento de preparacion de un derivado flavonico.
CH513099A (fr)	1971-09-30	Procédé de fabrication d'isomères trans des acides cyclopentanetétracarboxyliques 1,2,3,4
JPS51111237A (en)	1976-10-01	A novel method for preparing 1,8-naphthoylene benzimidazole derivative s
ES403313A1 (es)	1975-12-16	Procedimiento de obtencion de un nuevo derivado del acido 3,4,5 trimetoxibenzoico y sus sales.
AR197014A1 (es)	1974-03-08	Procedimiento para la preparacion de lactonas hidrolizadas de anillo a insaturadas de compuestos de 6,7-metilen-20-espiroxa-3,21 diona activos como antagonicos de aldosterona