FR2361909A1 - Procede pour la preparation de polysaccharides contenant de l'azote, et ayant des proprietes antitumorales, produits obtenus et leur utilisation en tant que medicaments - Google Patents

Procede pour la preparation de polysaccharides contenant de l'azote, et ayant des proprietes antitumorales, produits obtenus et leur utilisation en tant que medicaments

Info

Publication number
FR2361909A1
FR2361909A1 FR7710262A FR7710262A FR2361909A1 FR 2361909 A1 FR2361909 A1 FR 2361909A1 FR 7710262 A FR7710262 A FR 7710262A FR 7710262 A FR7710262 A FR 7710262A FR 2361909 A1 FR2361909 A1 FR 2361909A1
Authority
FR
France
Prior art keywords
products
preparation
fungus
containing nitrogen
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7710262A
Other languages
English (en)
Other versions
FR2361909B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kureha Corp
Original Assignee
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kureha Corp filed Critical Kureha Corp
Publication of FR2361909A1 publication Critical patent/FR2361909A1/fr
Application granted granted Critical
Publication of FR2361909B1 publication Critical patent/FR2361909B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/074—Ganoderma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Production d'un polysaccharide, contenant de l'azote, ayant une activité anti-tumeurs, par extraction d'un champignon du groupe des basidiomycètes avec un solvant aqueux. On soumet un champignon, appartenant au genre Coriolus des polyporacées, initialement avec de l'eau ou avec une solution aqueuse alcaline diluée, puis on effectue ensuite encore des stades d'extraction avec des solutions aqueuses alcalines, telles que des solutions d'hydroxyde de sodium, dont les concentrations croissent progressivement, mais restent cependant inférieures à 2 N. Obtention d'une substance qui, sous forme d'une poudre préparée par concentration, dialyse et cryodessiccation de l'extrait, est de couleur brune, est facilement soluble dans l'eau, dont la solution exerce d'intéressants effets anti-tumeurs et possède aussi d'autres très avantageuses propriétés pharmacodynamiques.
FR7710262A 1976-07-07 1977-04-05 Procede pour la preparation de polysaccharides contenant de l'azote, et ayant des proprietes antitumorales, produits obtenus et leur utilisation en tant que medicaments Granted FR2361909A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8066576A JPS536413A (en) 1976-07-07 1976-07-07 Preparation of n-containing polysaccharides

Publications (2)

Publication Number Publication Date
FR2361909A1 true FR2361909A1 (fr) 1978-03-17
FR2361909B1 FR2361909B1 (fr) 1983-02-11

Family

ID=13724651

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7710262A Granted FR2361909A1 (fr) 1976-07-07 1977-04-05 Procede pour la preparation de polysaccharides contenant de l'azote, et ayant des proprietes antitumorales, produits obtenus et leur utilisation en tant que medicaments

Country Status (28)

Country Link
US (1) US4229570A (fr)
JP (1) JPS536413A (fr)
AR (1) AR217256A1 (fr)
AT (1) AT360146B (fr)
AU (1) AU497397B2 (fr)
BE (1) BE853178A (fr)
BG (1) BG33008A3 (fr)
BR (1) BR7704434A (fr)
CA (1) CA1072033A (fr)
CH (1) CH628245A5 (fr)
CS (1) CS219325B2 (fr)
DD (1) DD130662A5 (fr)
DE (1) DE2713536C2 (fr)
DK (1) DK145424C (fr)
ES (1) ES457723A1 (fr)
FR (1) FR2361909A1 (fr)
GB (1) GB1570538A (fr)
HU (1) HU176828B (fr)
IN (1) IN144759B (fr)
IT (1) IT1075830B (fr)
MX (1) MX4255E (fr)
NL (1) NL169197C (fr)
PH (1) PH12619A (fr)
PL (1) PL103468B1 (fr)
SE (1) SE441893B (fr)
SU (1) SU704431A3 (fr)
YU (1) YU39796B (fr)
ZA (1) ZA773441B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2359203A1 (fr) * 1976-07-22 1978-02-17 Kureha Chemical Ind Co Ltd Polysaccharides, leur procede de preparation et medicaments les contenant
FR2361910A1 (fr) * 1976-07-07 1978-03-17 Kureha Chemical Ind Co Ltd Procede pour la production de polysaccharides contenant de l'azote et ayant des proprietes antitumorales, produits obtenus et leur utilisation en tant que medicament

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4851395A (en) * 1976-07-07 1989-07-25 Kureha Kagaku Kogyo Kabushiki Kausha Nitrogen-containing polysaccharide
JPS5394012A (en) * 1977-01-27 1978-08-17 Kureha Chem Ind Co Ltd Novel polysaccharide and its preparation
JPS5932480B2 (ja) * 1981-02-10 1984-08-09 呉羽化学工業株式会社 新規な糖蛋白複合体
US4614733A (en) * 1981-12-31 1986-09-30 Kureha Kagaku Kogyo Kabushiki Kaisha Polysaccharides pharmaceutical compositions and the use thereof
DE3448144C2 (fr) * 1983-08-11 1989-10-05 Kureha Kagaku Kogyo K.K., Tokio/Tokyo, Jp
JPH0643336B2 (ja) * 1988-06-30 1994-06-08 呉羽化学工業株式会社 血管増殖抑制剤
GB2304347A (en) 1995-08-11 1997-03-19 Boeringer Ingelheim Vetmedica Antigenic preparations
US7048932B2 (en) * 2002-05-22 2006-05-23 The Chinese University Of Hong Kong Preparation and standardization of immunomodulatory peptide-linked glucans with verifiable oral absorbability from coriolus versicolor
WO2005095413A1 (fr) * 2004-04-01 2005-10-13 Kureha Corporation Agent anti-tumeur
US7829098B2 (en) * 2005-11-08 2010-11-09 Vita Green Health Products Co., Ltd Herbal powder extracts and methods of preparing and using the same
JP5959523B2 (ja) * 2010-10-06 2016-08-02 バギ リサーチ リミテッド カワラタケ抽出物、その調製方法および使用
CN104804107B (zh) * 2015-04-24 2017-08-04 成都中医药大学 一种波棱瓜子多糖提取方法，该提取方法得到的波棱瓜子多糖提取物及用途

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2070133A1 (fr) * 1969-10-15 1971-09-10 Kureha Chemical Ind Co Ltd
JPS4948896A (fr) * 1972-09-16 1974-05-11
FR2335235A1 (fr) * 1975-12-18 1977-07-15 Kureha Chemical Ind Co Ltd Procede de preparation de substances anti-tumorales
FR2337144A1 (fr) * 1976-01-01 1977-07-29 Kureha Chemical Ind Co Ltd Polysaccharides a liaison de proteine
FR2361910A1 (fr) * 1976-07-07 1978-03-17 Kureha Chemical Ind Co Ltd Procede pour la production de polysaccharides contenant de l'azote et ayant des proprietes antitumorales, produits obtenus et leur utilisation en tant que medicament

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3382229A (en) * 1963-04-11 1968-05-07 Exxon Production Research Co Polysaccharide recovery process
US3436311A (en) * 1966-02-28 1969-04-01 Pillsbury Co Fungal polysaccharide composition and method for making same
US3759896A (en) * 1968-03-28 1973-09-18 T Yamamoto Process for manufacture of polysaccharides with antitumor action
US4051314A (en) * 1970-10-14 1977-09-27 Kureha Kagaku Kogyo Kabushiki Kaisha Polysaccharides and method for producing same
US3933788A (en) * 1971-11-11 1976-01-20 Kelco Company Polysaccharide and bacterial fermentation process for its preparation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2070133A1 (fr) * 1969-10-15 1971-09-10 Kureha Chemical Ind Co Ltd
JPS4948896A (fr) * 1972-09-16 1974-05-11
FR2335235A1 (fr) * 1975-12-18 1977-07-15 Kureha Chemical Ind Co Ltd Procede de preparation de substances anti-tumorales
FR2337144A1 (fr) * 1976-01-01 1977-07-29 Kureha Chemical Ind Co Ltd Polysaccharides a liaison de proteine
FR2361910A1 (fr) * 1976-07-07 1978-03-17 Kureha Chemical Ind Co Ltd Procede pour la production de polysaccharides contenant de l'azote et ayant des proprietes antitumorales, produits obtenus et leur utilisation en tant que medicament

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1974 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2361910A1 (fr) * 1976-07-07 1978-03-17 Kureha Chemical Ind Co Ltd Procede pour la production de polysaccharides contenant de l'azote et ayant des proprietes antitumorales, produits obtenus et leur utilisation en tant que medicament
FR2359203A1 (fr) * 1976-07-22 1978-02-17 Kureha Chemical Ind Co Ltd Polysaccharides, leur procede de preparation et medicaments les contenant

Also Published As

Publication number Publication date
DK145424B (da) 1982-11-15
AU497397B2 (en) 1978-12-14
SE7703264L (sv) 1978-01-08
YU39796B (en) 1985-04-30
US4229570A (en) 1980-10-21
BR7704434A (pt) 1978-03-28
NL169197C (nl) 1982-06-16
CH628245A5 (de) 1982-02-26
CS219325B2 (en) 1983-03-25
NL7703371A (nl) 1978-01-10
ES457723A1 (es) 1978-02-16
DK151977A (da) 1978-01-08
FR2361909B1 (fr) 1983-02-11
AT360146B (de) 1980-12-29
GB1570538A (en) 1980-07-02
MX4255E (es) 1982-03-05
DE2713536A1 (de) 1978-01-12
HU176828B (en) 1981-05-28
BE853178A (fr) 1977-08-01
IN144759B (fr) 1978-07-01
JPS536413A (en) 1978-01-20
PL197371A1 (pl) 1978-01-16
AR217256A1 (es) 1980-03-14
BG33008A3 (en) 1982-11-15
SU704431A3 (ru) 1979-12-15
DE2713536C2 (de) 1984-04-26
ATA219377A (de) 1980-05-15
PL103468B1 (pl) 1979-06-30
CA1072033A (fr) 1980-02-19
DK145424C (da) 1983-04-18
SE441893B (sv) 1985-11-18
IT1075830B (it) 1985-04-22
YU76477A (en) 1982-08-31
PH12619A (en) 1979-07-05
AU2416677A (en) 1978-10-19
ZA773441B (en) 1978-04-26
JPS5614275B2 (fr) 1981-04-03
DD130662A5 (de) 1978-04-19
NL169197B (nl) 1982-01-18

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