FR2446830A1 - Di:thienyl-piperidine derivs. - have e.g. anti-ischaemic and hypertensive activity and stimulate peripheral circulation - Google Patents
Di:thienyl-piperidine derivs. - have e.g. anti-ischaemic and hypertensive activity and stimulate peripheral circulationInfo
- Publication number
- FR2446830A1 FR2446830A1 FR8000893A FR8000893A FR2446830A1 FR 2446830 A1 FR2446830 A1 FR 2446830A1 FR 8000893 A FR8000893 A FR 8000893A FR 8000893 A FR8000893 A FR 8000893A FR 2446830 A1 FR2446830 A1 FR 2446830A1
- Authority
- FR
- France
- Prior art keywords
- alkyl
- thienyl
- ischaemic
- peripheral circulation
- hypertensive activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- SVUBKHLEMUNAQT-UHFFFAOYSA-N 1-thiophen-2-ylpiperidine Chemical compound C1CCCCN1C1=CC=CS1 SVUBKHLEMUNAQT-UHFFFAOYSA-N 0.000 title 1
- 230000003276 anti-hypertensive effect Effects 0.000 title 1
- 230000002253 anti-ischaemic effect Effects 0.000 title 1
- 230000003836 peripheral circulation Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- -1 salts N-oxide Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Di thienylpiperidines of formula (I) and their acid addn salts N-oxide, and quaternary salts are new. R1 is H or OH. R2 is H; or R1 and R2 form a double bond; R3 is H; 3-8C cycloalkyl, 1-20C alkyl opt. contg. 2 OH gps. or 2-6C hydroxyalkyl substd. on the H of the OH gp. by 3-8c cycloalkyl 1-6C alkyl, 1-6C hydroxyalkyl or hydroxyalkoxy-alkyl (alkoxy gp. is 2-6C and alkyl is 1-6C); R4-7 are H, 1-6C alkyl or halogen, >=1 thienyl-(3) gp. must be present if R3 is unsubstd. 1-6C alkyl.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7901660 | 1979-01-17 | ||
| GB7901659 | 1979-01-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2446830A1 true FR2446830A1 (en) | 1980-08-14 |
Family
ID=26270248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8000893A Withdrawn FR2446830A1 (en) | 1979-01-17 | 1980-01-16 | Di:thienyl-piperidine derivs. - have e.g. anti-ischaemic and hypertensive activity and stimulate peripheral circulation |
Country Status (5)
| Country | Link |
|---|---|
| AT (2) | AT369741B (en) |
| DD (1) | DD148775A5 (en) |
| DK (1) | DK18780A (en) |
| ES (2) | ES487741A0 (en) |
| FR (1) | FR2446830A1 (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU176903A1 (en) * | А. А. Пономарев , Н. И. Мартемь нова | METHOD OF OBTAINING CITRATE1-METHIL-3- | ||
| GB740740A (en) * | 1950-12-05 | 1955-11-16 | Schering Corp | Substituted piperidines |
| GB740689A (en) * | 1950-12-05 | 1955-11-16 | Schering Corp | Substituted piperidines |
| CH333016A (en) * | 1954-02-05 | 1958-09-30 | Ciba Geigy | Process for the production of new piperidines |
-
1980
- 1980-01-15 DD DD21847080A patent/DD148775A5/en unknown
- 1980-01-16 AT AT21780A patent/AT369741B/en not_active IP Right Cessation
- 1980-01-16 AT AT21680A patent/ATA21680A/en not_active IP Right Cessation
- 1980-01-16 FR FR8000893A patent/FR2446830A1/en not_active Withdrawn
- 1980-01-16 ES ES487741A patent/ES487741A0/en active Granted
- 1980-01-16 DK DK18780A patent/DK18780A/en unknown
- 1980-01-16 ES ES487740A patent/ES8100266A1/en not_active Expired
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU176903A1 (en) * | А. А. Пономарев , Н. И. Мартемь нова | METHOD OF OBTAINING CITRATE1-METHIL-3- | ||
| GB740740A (en) * | 1950-12-05 | 1955-11-16 | Schering Corp | Substituted piperidines |
| GB740689A (en) * | 1950-12-05 | 1955-11-16 | Schering Corp | Substituted piperidines |
| CH333016A (en) * | 1954-02-05 | 1958-09-30 | Ciba Geigy | Process for the production of new piperidines |
Non-Patent Citations (1)
| Title |
|---|
| CA1966 * |
Also Published As
| Publication number | Publication date |
|---|---|
| ES8100267A1 (en) | 1980-11-01 |
| ATA21680A (en) | 1982-08-15 |
| ES487741A0 (en) | 1980-11-01 |
| AT369741B (en) | 1983-01-25 |
| ATA21780A (en) | 1982-06-15 |
| ES487740A0 (en) | 1980-11-01 |
| DK18780A (en) | 1980-07-18 |
| DD148775A5 (en) | 1981-06-10 |
| ES8100266A1 (en) | 1980-11-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Withdrawal of published application |