FR2456738B2 - - Google Patents

Info

Publication number
FR2456738B2
FR2456738B2 FR7833468A FR7833468A FR2456738B2 FR 2456738 B2 FR2456738 B2 FR 2456738B2 FR 7833468 A FR7833468 A FR 7833468A FR 7833468 A FR7833468 A FR 7833468A FR 2456738 B2 FR2456738 B2 FR 2456738B2
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7833468A
Other versions
FR2456738A2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/894,965 external-priority patent/US4178442A/en
Application filed by Delalande SA filed Critical Delalande SA
Publication of FR2456738A2 publication Critical patent/FR2456738A2/fr
Application granted granted Critical
Publication of FR2456738B2 publication Critical patent/FR2456738B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02—Seven-membered rings
    • C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/54—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FR7833468A 1978-04-10 1978-11-27 Nouvelles cinnamoyles piperazines et homopiperazines, leur procede de preparation et leur application en therapeutique Granted FR2456738A2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/894,965 US4178442A (en) 1977-04-19 1978-04-10 Novel cinnamoyles piperazines and homopiperazines, the method of preparing them and their application in therapeutics

Publications (2)

Publication Number Publication Date
FR2456738A2 FR2456738A2 (fr) 1980-12-12
FR2456738B2 true FR2456738B2 (fr) 1983-01-14

Family

ID=25403749

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7833468A Granted FR2456738A2 (fr) 1978-04-10 1978-11-27 Nouvelles cinnamoyles piperazines et homopiperazines, leur procede de preparation et leur application en therapeutique
FR7917586A Granted FR2438044A2 (fr) 1978-04-10 1979-07-06 Nouveaux derives de l'alkylene dioxy-1, 2 benzene

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7917586A Granted FR2438044A2 (fr) 1978-04-10 1979-07-06 Nouveaux derives de l'alkylene dioxy-1, 2 benzene

Country Status (3)

Country Link
FR (2) FR2456738A2 (fr)
LU (1) LU80680A1 (fr)
SE (2) SE438149B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2507604A2 (fr) * 1977-04-19 1982-12-17 Delalande Sa Nouvelles trimethoxy-3,4,5 cinnamoyle piperazines, leur procede de preparation et leur application en therapeutique
FR2497512A2 (fr) * 1981-01-07 1982-07-09 Delalande Sa Nouveaux derives de la trimethoxy-3,4,5 cinnamoyl piperazine, leurs sels, leur procede de preparation et leur application en therapeutique
ES530269A0 (es) * 1983-03-04 1985-12-01 Otsuka Pharma Co Ltd Derivados de indano y sus sales
US4499100A (en) * 1983-05-18 1985-02-12 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethyleneamino-piperidinyl acetanilides, ketones, esters and carbamates which effect immunity and calcium entry and β-blockade
US4567264A (en) * 1983-05-18 1986-01-28 Syntex (U.S.A.) Inc. Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry
US4558129A (en) * 1983-05-18 1985-12-10 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade
DE3407695A1 (de) * 1984-03-02 1985-09-12 Röhm Pharma GmbH, 6108 Weiterstadt Pteridinverbindungen mit pharmazeutischer wirksamkeit
EP0338906B1 (fr) * 1988-04-16 1994-10-05 Daicel Chemical Industries, Ltd. Procédé de moulage d'un substrat formaté pour disque optique et moule pour la mise en oeuvre du procédé
US6514996B2 (en) 1995-05-19 2003-02-04 Kyowa Hakko Kogyo Co., Ltd. Derivatives of benzofuran or benzodioxole
EP0943613A4 (fr) * 1996-11-19 2002-07-10 Kyowa Hakko Kogyo Kk Composes heterocycliques d'oxygene

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1509527A (en) * 1974-06-05 1978-05-04 Ici Ltd 1-(aryl-or heteroaryl)oxy-3-(substituted-amino)propan-2-ol derivatives processes for their manufacture and pharmaceutical compositions containing them
FR2267104A1 (en) * 1974-04-12 1975-11-07 Ferlux Labo Sa Hypotensive and antiarrhythmic piperazines - 1-(3-phenoxy-2-hydroxy propyl)-4-substd. piperazines
FR2387971A1 (fr) * 1977-04-19 1978-11-17 Delalande Sa Nouvelles trimethoxy cinnamoyles piperazines, leur procede de preparation et leur application en therapeutique
FR2396757A2 (fr) * 1977-07-08 1979-02-02 Ile De France Nouveaux 2,3-alkylene bis (oxy) benzamides substitues, leurs derives et leurs procedes de preparation

Also Published As

Publication number Publication date
SE431752B (sv) 1984-02-27
FR2438044A2 (fr) 1980-04-30
SE7900020L (sv) 1979-10-11
SE438149B (sv) 1985-04-01
FR2456738A2 (fr) 1980-12-12
FR2438044B2 (fr) 1982-04-09
SE7907312L (sv) 1979-10-11
LU80680A1 (fr) 1980-07-21

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Legal Events

Date Code Title Description
TP Transmission of property