FR2469178A1 - Solution aqueuse de nitroglycerine et composition pharmaceutique renfermant cette solution - Google Patents

Solution aqueuse de nitroglycerine et composition pharmaceutique renfermant cette solution

Info

Publication number
FR2469178A1
FR2469178A1 FR8024070A FR8024070A FR2469178A1 FR 2469178 A1 FR2469178 A1 FR 2469178A1 FR 8024070 A FR8024070 A FR 8024070A FR 8024070 A FR8024070 A FR 8024070A FR 2469178 A1 FR2469178 A1 FR 2469178A1
Authority
FR
France
Prior art keywords
pharmaceutical composition
composition containing
same
solution
nitroglycerin solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8024070A
Other languages
English (en)
Other versions
FR2469178B1 (fr
Inventor
Takaaki Ohkuma
Hiroshi Ninomiya
Masaaki Nakamura
Genichi Idzu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Kayaku Co Ltd
Original Assignee
Nippon Kayaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kayaku Co Ltd filed Critical Nippon Kayaku Co Ltd
Publication of FR2469178A1 publication Critical patent/FR2469178A1/fr
Application granted granted Critical
Publication of FR2469178B1 publication Critical patent/FR2469178B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

SOLUTION AQUEUSE DE NITROGLYCERINE ET COMPOSITION PHARMACEUTIQUE RENFERMANT CETTE SOLUTION. LA PRESENTE INVENTION DECRIT UNE SOLUTION AQUEUSE DE NITROGLYCERINE COMPRENANT AU MOINS UNE SUBSTANCE CHOISIE PARMI LE SORBITOL, LE MANNITOL ET LE XYLITOL EN PLUS DE LA NITROGLYCERINE ET AYANT UN DEGRE ELEVE DE STABILITE AU STOCKAGE. UTILISATION DE CETTE SOLUTION POUR PREPARER DES INJECTIONS.
FR8024070A 1979-11-13 1980-11-12 Solution aqueuse de nitroglycerine et composition pharmaceutique renfermant cette solution Granted FR2469178A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54146011A JPS599539B2 (ja) 1979-11-13 1979-11-13 ニトログリセリン水溶液及びその製造法

Publications (2)

Publication Number Publication Date
FR2469178A1 true FR2469178A1 (fr) 1981-05-22
FR2469178B1 FR2469178B1 (fr) 1983-12-23

Family

ID=15398067

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8024070A Granted FR2469178A1 (fr) 1979-11-13 1980-11-12 Solution aqueuse de nitroglycerine et composition pharmaceutique renfermant cette solution

Country Status (9)

Country Link
US (1) US4323577A (fr)
JP (1) JPS599539B2 (fr)
CA (1) CA1163199A (fr)
DE (1) DE3042332A1 (fr)
DK (1) DK161186C (fr)
ES (1) ES8201419A1 (fr)
FR (1) FR2469178A1 (fr)
GB (1) GB2062467B (fr)
IT (1) IT1147022B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1163561A (fr) * 1979-11-06 1984-03-13 Cyril Boroda Preparation contenant de la nitroglycerine et parfois d'autres medicaments et methode de preparation
DE3109783C2 (de) * 1981-03-13 1987-04-02 Schwarz GmbH, 4019 Monheim Verfahren zur Herstellung einer ethanolfreien Nitroglycerinlösung mit einer Konzentration von etwa 1 mg Nitroglycerin/ml
DE3237284A1 (de) * 1982-10-08 1984-04-12 G. Pohl-Boskamp GmbH & Co Chemisch-pharmazeutische Fabrik, 2214 Hohenlockstedt Loesungsvermittlerfreie, waessrige nitroglycerinloesung
JPH0653658B2 (ja) * 1984-12-17 1994-07-20 中外製薬株式会社 安定な錠剤の製造法
JPH0665647B2 (ja) * 1985-06-12 1994-08-24 株式会社三和化学研究所 移植皮膚処置剤
KR950010150B1 (ko) * 1986-01-14 1995-09-11 쥬우가이세이야꾸 가부시끼가이샤 니코란딜 함유 주사제의 안정화 방법
KR940000232B1 (ko) * 1986-01-17 1994-01-12 쥬우가이세이야꾸 가부시끼가이샤 니코란딜 제제의 안정화 방법
FI871447A7 (fi) * 1986-04-07 1987-10-08 Bristol Myers Co Stabila injicerbara antivomitiva kompositioner.
US4882356A (en) * 1987-03-10 1989-11-21 Nassar Munir N Stable injectable antiemetic compositions
US4816568A (en) * 1986-05-16 1989-03-28 International Minerals & Chemical Corp. Stabilization of growth hormones
US4879308A (en) * 1987-08-11 1989-11-07 Lyphomed, Inc. Aqueous nitroglycerin injection and manufacturing process
US5001151A (en) * 1987-08-11 1991-03-19 Fujisawa Usa, Inc. Aqueous nitroglycerin injection and manufacturing process
JPH0645538B2 (ja) * 1987-09-30 1994-06-15 日本化薬株式会社 ニトログリセリンスプレー剤
DE4026072A1 (de) * 1990-08-17 1992-02-20 Sanol Arznei Schwarz Gmbh Nitroglycerinhaltiger, hydrophiler, waessriger pumpspray
ES2059264B1 (es) * 1992-11-05 1995-06-16 Berrazueta Fernandez Jose Ramo Utilizacion de los nitrovasodilatadores en la preparacion de medicamentos antiinflamatorios y analgesicos de uso topico.
IL122752A (en) 1995-06-27 2001-07-24 Boehringer Ingelheim Kg Stable preparations for creating propellant-free sprays
JO2735B1 (en) * 2003-01-30 2013-09-15 هيلسين هيلث كير أس ايه. Liquid pharmaceutical formulations of palonosetron
DE202008007318U1 (de) * 2008-03-14 2008-07-31 G. Pohl-Boskamp Gmbh & Co. Kg Langzeitstabile pharmazeutische Zubereitung mit dem Wirkstoff Glyceroltrinitrat
EP2600837A1 (fr) 2010-08-03 2013-06-12 G. Pohl-Boskamp GmbH & Co. KG Utilisation de trinitrate de glycéryle pour le traitement d'hématomes
EP2678006B1 (fr) 2011-02-25 2015-12-30 G. Pohl-Boskamp GmbH & Co. KG Conditionnement de préparations pharmaceutiques solides contenant la substance active trinitrate de glycéryle
EP2668947B1 (fr) 2012-05-31 2016-11-30 G. Pohl-Boskamp GmbH & Co. KG Induction de l'artériogénèse par un donneur d'oxyde nitrique tel que la nitroglycérine
US9248099B2 (en) 2012-05-31 2016-02-02 Desmoid Aktiengesellschaft Use of stabilized granules containing glyceryl trinitrate for arteriogenesis
EP2878310B1 (fr) 2013-11-29 2017-01-11 G. Pohl-Boskamp GmbH & Co. KG Composition aqueuse pulvérisable comprenant du trinitrate de glycéryle
CN116251057B (zh) * 2022-12-29 2024-06-07 平光制药股份有限公司 一种硝酸异山梨酯注射液及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2213779A1 (fr) * 1973-01-13 1974-08-09 Byk Gulden Lomberg Chem Fab
FR2285896A1 (fr) * 1974-09-24 1976-04-23 Nippon Kayaku Kk Preparation pharmaceutique destinee a l'administration dans la cavite buccale

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE632504A (fr) * 1962-05-24
CH513760A (it) 1970-10-14 1971-10-15 I B Anstalt Impianto automatico di caricamento di fardelli di formato uniforme su veicoli

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2213779A1 (fr) * 1973-01-13 1974-08-09 Byk Gulden Lomberg Chem Fab
FR2285896A1 (fr) * 1974-09-24 1976-04-23 Nippon Kayaku Kk Preparation pharmaceutique destinee a l'administration dans la cavite buccale
GB1516359A (en) * 1974-09-24 1978-07-05 Nippon Kayaku Kk Pharmaceutical preparation for oral cavity administration

Also Published As

Publication number Publication date
JPS599539B2 (ja) 1984-03-03
IT1147022B (it) 1986-11-19
GB2062467A (en) 1981-05-28
IT8050122A0 (it) 1980-11-11
CA1163199A (fr) 1984-03-06
JPS5671046A (en) 1981-06-13
GB2062467B (en) 1983-07-20
DK482180A (da) 1981-05-14
US4323577A (en) 1982-04-06
DK161186B (da) 1991-06-10
DE3042332A1 (de) 1981-05-21
DK161186C (da) 1991-11-25
DE3042332C2 (fr) 1988-08-25
FR2469178B1 (fr) 1983-12-23
ES496747A0 (es) 1981-11-16
ES8201419A1 (es) 1981-11-16

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Legal Events

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