GEP20074025B - Process for preparing acid salts of gemifloxacin - Google Patents

Process for preparing acid salts of gemifloxacin

Info

Publication number: GEP20074025B
Authority: GE; Georgia
Prior art keywords: gemifloxacin; acid salts; preparing acid; improvement; preparing
Prior art date: 2002-04-08

Application number

GEAP8436A

Other languages

English (en)

Inventor

Hoon Choi

Sang-Chul Choi

Do-Hyun Nam

Bo-Seung Choi

Original Assignee

Lg Life Sciences Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-08

Filing date

2003-04-04

Publication date

2007-01-25

2003-04-04 Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd

2007-01-25 Publication of GEP20074025B publication Critical patent/GEP20074025B/en

Links

239000002253 acid Substances 0.000 title 1
ZRCVYEYHRGVLOC-HYARGMPZSA-N gemifloxacin Chemical class C1C(CN)C(=N/OC)/CN1C(C(=C1)F)=NC2=C1C(=O)C(C(O)=O)=CN2C1CC1 ZRCVYEYHRGVLOC-HYARGMPZSA-N 0.000 title 1
229960003170 gemifloxacin Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
150000003839 salts Chemical class 0.000 title 1
238000000034 method Methods 0.000 abstract 5

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Saccharide Compounds (AREA)

GEAP8436A 2002-04-08 2003-04-04 Process for preparing acid salts of gemifloxacin GEP20074025B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
KR10-2002-0018847A KR100517638B1 (ko)	2002-04-08	2002-04-08	게미플록사신 산염의 새로운 제조방법

Publications (1)

Publication Number	Publication Date
GEP20074025B true GEP20074025B (en)	2007-01-25

Family

ID=36241771

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GEAP8436A GEP20074025B (en)	2002-04-08	2003-04-04	Process for preparing acid salts of gemifloxacin

Country Status (31)

Country	Link
US (1)	US7361762B2 (de)
EP (1)	EP1497290B1 (de)
JP (1)	JP4315815B2 (de)
KR (1)	KR100517638B1 (de)
CN (1)	CN1291987C (de)
AP (1)	AP1786A (de)
AT (1)	ATE404559T1 (de)
AU (1)	AU2003219581B2 (de)
BR (1)	BRPI0309037B8 (de)
CA (1)	CA2481217C (de)
CO (1)	CO5611198A2 (de)
CY (1)	CY1108469T1 (de)
DE (1)	DE60322872D1 (de)
DK (1)	DK1497290T3 (de)
EA (1)	EA007222B1 (de)
ES (1)	ES2311694T3 (de)
GE (1)	GEP20074025B (de)
HR (1)	HRP20040929B1 (de)
IL (1)	IL164328A (de)
IS (1)	IS2731B (de)
MA (1)	MA26408A1 (de)
MX (1)	MXPA04009777A (de)
NO (1)	NO330042B1 (de)
NZ (1)	NZ536174A (de)
OA (1)	OA12801A (de)
PL (1)	PL372815A1 (de)
PT (1)	PT1497290E (de)
SI (1)	SI1497290T1 (de)
UA (1)	UA77070C2 (de)
WO (1)	WO2003087100A1 (de)
ZA (1)	ZA200408088B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2314082T3 (es) *	2001-08-02	2009-03-16	Lg Life Sciences Limited	Procedimientos para la produccion de derivados amino protegidos de 4-aminometilenpirrolidin-3-ona, gemifloxacina y sus sales.
WO2006134431A1 (en) *	2005-05-03	2006-12-21	Ranbaxy Laboratories Limited	Formate salt of gemifloxacin
US7834027B2 (en) *	2005-06-15	2010-11-16	Hetero Drugs Limited	Gemifloxacin process and polymorphs
CN101500564B (zh) *	2006-03-07	2012-07-25	沃克哈特有限公司	苯并喹嗪-2-羧酸的前药
WO2008053324A1 (en) *	2006-10-31	2008-05-08	Orchid Chemicals & Pharmaceuticals Limited	An improved process for the preparation of gemifloxacin mesylate

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PL166381B1 (pl)	1989-08-16	1995-05-31	Pfizer	Sposób wytwarzania nowych podstawionych kwasów 7-azabicyklochinolonokarboksylowych PL PL PL PL
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JPH0673056A (ja)	1992-08-26	1994-03-15	Kaken Pharmaceut Co Ltd	キノリンカルボン酸誘導体およびその塩
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DK0688772T3 (da) *	1994-06-16	1999-11-01	Lg Chemical Ltd	Quinolincarboxylsyrederivater med 7-(4-aminomethyl-3-oxim)-pyrrolidinsubstituenter og fremgangsmåde til deres fremstilling
JP3449658B2 (ja)	1994-12-21	2003-09-22	杏林製薬株式会社	安定性に優れた８−アルコキシキノロンカルボン酸水和物並びにその製造方法
DE69503066T2 (de)	1995-06-06	1998-10-15	Pfizer Inc., New York, N.Y.	KRISTALLFORM VON WASSERFREIEN 7-((1a,5a,6a)-6-AMINO-3-AZABICYCLO (3.1.0.) HEX-3-YL)-6-FLUORO-1-(2,4-DIFLUOROPHENYL)-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDIN-CARBONSÄURE METHANESULFONSÄURE SALZ
IL122649A (en)	1995-08-11	2001-08-26	Pfizer	(1s, 2s) - 1- (4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol methanesulfonate trihydrate, its use in the preparation of medicaments and pharmaceutical compositions comprising same
UA49880C2 (uk)	1996-03-29	2002-10-15	Смітклайн Бічам Корпорейшн	Дигідрат ерпоcартану, фармацевтична композиція, спосіб отримання твердої дозованої форми, спосіб блокування рецепторів ангіотензину іі
MA24500A1 (fr) *	1997-03-21	1998-10-01	Lg Life Sciences Ltd	Derive du sel d'acide carboxylique de naphthyridine .
KR100286874B1 (ko) *	1998-03-04	2001-04-16	성재갑	보호된 4-아미노메틸-피롤리딘-3-온의 제조방법
EP1082300B1 (de)	1998-05-29	2003-09-10	PHARMACIA & UPJOHN COMPANY	3-[(1'-n-methylamino)ethyl-n-benzyl]pyrrolidin-monomethanesulfonat
GB9820405D0 (en)	1998-09-18	1998-11-11	Smithkline Beecham Plc	Process
DK1223935T3 (da)	1999-06-29	2008-02-04	Lg Life Sciences Ltd	Anvendelse af gemifloxacinforbindelser mod bakterier
AU6947900A (en)	1999-09-01	2001-03-26	Smithkline Beecham Corporation	Methods of use of fluoroquinolone compounds against bacteria
GB9920917D0 (en) *	1999-09-03	1999-11-10	Sb Pharmco Inc	Novel process
GB9920919D0 (en)	1999-09-03	1999-11-10	Sb Pharmco Inc	Novel compound
EP1242079A4 (de)	1999-09-22	2003-01-22	Smithkline Beecham	Methode zur anti-bakteriellen verwendung von fluoroquinolon-verbindungen
KR20010091379A (ko)	2000-03-15	2001-10-23	성재갑	7-(4-아미노메틸-3-옥심)피롤리딘 치환체를 갖는 퀴놀린카르복실산 유도체의 신규 제조방법
KR20020018560A (ko)	2000-09-01	2002-03-08	성재갑	3-아미노메틸-4-ｚ-메톡시이미노피롤리딘의 신규 제조방법

2002
- 2002-04-08 KR KR10-2002-0018847A patent/KR100517638B1/ko not_active Expired - Lifetime
2003
- 2003-04-04 AT AT03715805T patent/ATE404559T1/de active
- 2003-04-04 BR BRPI0309037A patent/BRPI0309037B8/pt not_active IP Right Cessation
- 2003-04-04 PT PT03715805T patent/PT1497290E/pt unknown
- 2003-04-04 EA EA200401328A patent/EA007222B1/ru not_active IP Right Cessation
- 2003-04-04 DK DK03715805T patent/DK1497290T3/da active
- 2003-04-04 JP JP2003584056A patent/JP4315815B2/ja not_active Expired - Fee Related
- 2003-04-04 PL PL03372815A patent/PL372815A1/xx not_active Application Discontinuation
- 2003-04-04 EP EP03715805A patent/EP1497290B1/de not_active Expired - Lifetime
- 2003-04-04 NZ NZ536174A patent/NZ536174A/en not_active IP Right Cessation
- 2003-04-04 MX MXPA04009777A patent/MXPA04009777A/es active IP Right Grant
- 2003-04-04 OA OA1200400271A patent/OA12801A/en unknown
- 2003-04-04 HR HRP20040929AA patent/HRP20040929B1/hr not_active IP Right Cessation
- 2003-04-04 CA CA2481217A patent/CA2481217C/en not_active Expired - Lifetime
- 2003-04-04 ES ES03715805T patent/ES2311694T3/es not_active Expired - Lifetime
- 2003-04-04 WO PCT/KR2003/000683 patent/WO2003087100A1/en not_active Ceased
- 2003-04-04 US US10/510,514 patent/US7361762B2/en not_active Expired - Lifetime
- 2003-04-04 AU AU2003219581A patent/AU2003219581B2/en not_active Ceased
- 2003-04-04 GE GEAP8436A patent/GEP20074025B/en unknown
- 2003-04-04 AP APAP/P/2004/003148A patent/AP1786A/en active
- 2003-04-04 SI SI200331341T patent/SI1497290T1/sl unknown
- 2003-04-04 DE DE60322872T patent/DE60322872D1/de not_active Expired - Lifetime
- 2003-04-04 UA UA20041008144A patent/UA77070C2/uk unknown
- 2003-04-04 CN CNB038095483A patent/CN1291987C/zh not_active Expired - Lifetime
2004
- 2004-09-30 IS IS7477A patent/IS2731B/is unknown
- 2004-10-05 CO CO04099283A patent/CO5611198A2/es active IP Right Grant
- 2004-10-07 ZA ZA200408088A patent/ZA200408088B/xx unknown
- 2004-10-07 MA MA27894A patent/MA26408A1/fr unknown
- 2004-10-21 IL IL164328A patent/IL164328A/en unknown
- 2004-10-27 NO NO20044629A patent/NO330042B1/no not_active IP Right Cessation
2008
- 2008-10-31 CY CY20081101234T patent/CY1108469T1/el unknown

Also Published As

Publication number	Publication date
UA77070C2 (uk)	2006-10-16
PL372815A1 (en)	2005-08-08
NO330042B1 (no)	2011-02-07
IS2731B (is)	2011-04-15
IS7477A (is)	2004-09-30
CN1649868A (zh)	2005-08-03
BRPI0309037B8 (pt)	2021-05-25
HK1074440A1 (en)	2005-11-11
EP1497290A1 (de)	2005-01-19
NO20044629L (no)	2004-10-27
JP4315815B2 (ja)	2009-08-19
ZA200408088B (en)	2006-05-31
CO5611198A2 (es)	2006-02-28
OA12801A (en)	2006-07-11
EA200401328A1 (ru)	2005-06-30
CY1108469T1 (el)	2014-04-09
AP2004003148A0 (en)	2004-12-31
CA2481217C (en)	2010-06-01
KR20030080292A (ko)	2003-10-17
DE60322872D1 (de)	2008-09-25
BR0309037A (pt)	2005-02-01
HRP20040929A2 (en)	2005-02-28
DK1497290T3 (da)	2008-12-15
IL164328A (en)	2009-08-03
US20050148622A1 (en)	2005-07-07
MXPA04009777A (es)	2004-12-13
MA26408A1 (fr)	2004-12-01
AP1786A (en)	2007-10-04
PT1497290E (pt)	2008-11-14
KR100517638B1 (ko)	2005-09-28
AU2003219581B2 (en)	2006-08-24
NZ536174A (en)	2006-09-29
BRPI0309037B1 (pt)	2018-07-31
JP2005529112A (ja)	2005-09-29
EP1497290B1 (de)	2008-08-13
EA007222B1 (ru)	2006-08-25
US7361762B2 (en)	2008-04-22
CA2481217A1 (en)	2003-10-23
SI1497290T1 (sl)	2008-12-31
WO2003087100A1 (en)	2003-10-23
ATE404559T1 (de)	2008-08-15
CN1291987C (zh)	2006-12-27
HRP20040929B1 (hr)	2013-12-06
ES2311694T3 (es)	2009-02-16
EP1497290A4 (de)	2006-05-10
IL164328A0 (en)	2005-12-18
AU2003219581A1 (en)	2003-10-27

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