GR3017304T3 - Derivatives of pyridone carboxylic acids substituted by an azetidine, their preparation and their use as medicines. - Google Patents

Derivatives of pyridone carboxylic acids substituted by an azetidine, their preparation and their use as medicines.

Info

Publication number: GR3017304T3
Authority: GR; Greece
Prior art keywords: azetidine; derivatives; carboxylic acids; medicines; preparation
Prior art date: 1989-03-16

Application number

GR950402431T

Other languages

English (en)

Inventor

Corominas Juan Pares

Pinol Augusto Colombo

Constansa Jordi Frigola

Original Assignee

Esteve Labor Dr

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-16

Filing date

1995-09-06

Publication date

1995-12-31

1989-03-16 Priority claimed from FR8903459A external-priority patent/FR2644455B1/fr

1989-06-29 Priority claimed from FR8908695A external-priority patent/FR2649106A2/fr

1989-11-20 Priority claimed from FR8915178A external-priority patent/FR2654728B2/fr

1995-09-06 Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr

1995-12-31 Publication of GR3017304T3 publication Critical patent/GR3017304T3/el

Links

HONIICLYMWZJFZ-UHFFFAOYSA-N azetidine Chemical compound C1CNC1 HONIICLYMWZJFZ-UHFFFAOYSA-N 0.000 title abstract 2
239000003814 drug Substances 0.000 title abstract 2
229940079593 drug Drugs 0.000 title 1
YILGXIZRZUDENO-UHFFFAOYSA-N 10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5,7,9(13),11-tetraene-11-carboxylic acid Chemical class C1COC2=CC=CC3=C2N1C=C(C(=O)O)C3=O YILGXIZRZUDENO-UHFFFAOYSA-N 0.000 abstract 1
ILNJBIQQAIIMEY-UHFFFAOYSA-N 4-oxo-1h-quinoline-3-carboxylic acid Chemical compound C1=CC=CC2=C(O)C(C(=O)O)=CN=C21 ILNJBIQQAIIMEY-UHFFFAOYSA-N 0.000 abstract 1
ZMMAJVZOYAEFNK-UHFFFAOYSA-N 4-oxo-3h-1,8-naphthyridine-3-carboxylic acid Chemical compound C1=CC=C2C(=O)C(C(=O)O)C=NC2=N1 ZMMAJVZOYAEFNK-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
150000001539 azetidines Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)

GR950402431T 1989-03-16 1995-09-06 Derivatives of pyridone carboxylic acids substituted by an azetidine, their preparation and their use as medicines. GR3017304T3 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR8903459A FR2644455B1 (fr)	1989-03-16	1989-03-16	Derives d'acides pyridone carboxyliques azetidinyl substitues, leur preparation et leur application en tant que medicaments
FR8908695A FR2649106A2 (fr)	1989-06-29	1989-06-29	Derives d'acides pyridone carboxyliques azetidinyl substitues, leur preparation et leur application en tant que medicament
FR8915178A FR2654728B2 (fr)	1989-03-16	1989-11-20	Derives d'acides pyridone carboxyliques azetidinyl substitues, leur preparation et leur application en tant que medicament.

Publications (1)

Publication Number	Publication Date
GR3017304T3 true GR3017304T3 (en)	1995-12-31

Family

ID=27251837

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR950402431T GR3017304T3 (en)	1989-03-16	1995-09-06	Derivatives of pyridone carboxylic acids substituted by an azetidine, their preparation and their use as medicines.

Country Status (16)

Country	Link
US (1)	US5393758A (el)
EP (1)	EP0388298B1 (el)
JP (1)	JPH075586B2 (el)
KR (1)	KR940006595B1 (el)
AT (1)	ATE124039T1 (el)
AU (2)	AU638437B2 (el)
CA (1)	CA2012223A1 (el)
DE (1)	DE69020199T2 (el)
DK (1)	DK0388298T3 (el)
ES (1)	ES2022006A6 (el)
GR (1)	GR3017304T3 (el)
HU (1)	HU206702B (el)
NO (1)	NO177302C (el)
PT (1)	PT93450B (el)
RU (1)	RU2044735C1 (el)
YU (1)	YU47430B (el)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5342846A (en) *	1990-12-05	1994-08-30	Synphar Laboratories, Inc.	7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents
WO1992010492A1 (en) *	1990-12-05	1992-06-25	Synphar Laboratories, Inc.	7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds useful as antibacterial agents
FR2676445B1 (fr) *	1991-05-16	1995-02-03	Esteve Labor Dr	Derives de pyridone amino acide azetidinyl substitues, leur preparation et leur application en tant que medicaments.
FR2681865B1 (fr) *	1991-10-01	1993-11-19	Bel Laboratoire Roger	Nouveaux derives de la benzonaphtyridine-1,8 leur preparation et les compositions qui les contiennent.
US5221676A (en) *	1992-02-06	1993-06-22	Warner-Lambert Company	7-substituted quinolones and naphthyridones as antibacterial agents
FR2690161B1 (fr) *	1992-04-16	1995-06-30	Esteve Labor Dr	Derives de pyridone azetidinyl substitues avec activite antimicrobienne.
JPH0999195A (ja) *	1995-10-02	1997-04-15	Eiji Maruko	高能率電子洗濯法
ZA984527B (en) *	1997-05-30	1998-12-03	Daiichi Seiyaku Co	Substituted cyclobutylamine derivative
IL147043A0 (en) *	1999-07-01	2002-08-14	Wakunaga Pharma Co Ltd	Quinolinecarboxylic acid derivative or salts thereof
RU2298006C2 (ru) *	2000-11-20	2007-04-27	Дайити Фармасьютикал Ко., Лтд.	Дегалогенированные соединения, антибактериальное средство и терапевтическое средство на их основе, способ получения антибактериального или лекарственного средства, применение дегалогенированных соединений для получения антибактериального или лекарственного средства
WO2005026146A1 (en) *	2003-09-12	2005-03-24	Warner-Lambert Company Llc	Azetidinyl quinolones as antibacterial agents

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3998808A (en) *	1968-05-22	1976-12-21	Velsicol Chemical Corporation	Compositions of matter D-hetero-1,1-(α-thiocyanoacetyl) compounds
US4183923A (en) *	1977-11-07	1980-01-15	Schering Corporation	Antipsoriatic compositions
JPS5746986A (en) *	1980-09-02	1982-03-17	Dai Ichi Seiyaku Co Ltd	Pyrido(1,2,3-de)(1,4)benzoxazine derivative
US4665079A (en) *	1984-02-17	1987-05-12	Warner-Lambert Company	Antibacterial agents
US4777175A (en) *	1982-09-09	1988-10-11	Warner-Lambert Company	Antibacterial agents
IE55898B1 (en) *	1982-09-09	1991-02-14	Warner Lambert Co	Antibacterial agents
JPS6089480A (ja) *	1983-10-21	1985-05-20	Dainippon Pharmaceut Co Ltd	ピリドンカルボン酸誘導体
JPS60126284A (ja) *	1983-12-09	1985-07-05	Dainippon Pharmaceut Co Ltd	ピリドンカルボン酸誘導体およびその塩
FR2560194B1 (fr) *	1984-02-27	1987-08-07	Midy Spa	3-aminoazetidine, ses sels, procede pour leur preparation et intermediaires de synthese
JPS61137885A (ja) *	1984-12-08	1986-06-25	Dainippon Pharmaceut Co Ltd	１，８−ナフチリジン誘導体、そのエステルおよびその塩
JPS61143383A (ja) *	1985-10-28	1986-07-01	Toyama Chem Co Ltd	１，４−ジヒドロ−４−オキソナフチリジン誘導体またはその塩を含有する抗菌剤
JPS63198664A (ja) *	1986-03-31	1988-08-17	Sankyo Co Ltd	キノロンカルボン酸誘導体
DK164287A (da) *	1986-03-31	1987-10-01	Sankyo Co	Quinolin-3-carboxylsyrederivater og fremgangsmaade til fremstilling deraf og deres anvendelse
JPH0633262B2 (ja) *	1987-10-12	1994-05-02	富山化学工業株式会社	１，４−ジヒドロ−４−オキソナフチリジン誘導体およびその塩
WO1989003828A1 (en) *	1987-10-26	1989-05-05	Pfizer Inc.	Azetidinyl quinolone carboxylic acids and esters
FR2634483B2 (fr) *	1987-12-29	1994-03-04	Esteve Labor Dr	Derives des acides 7-(1-azetidinyl)-1,4-dihydro-4-oxoquinoleine-3-carboxyliques, leur preparation et leur application en tant que medicaments

1990
- 1990-03-13 NO NO901171A patent/NO177302C/no unknown
- 1990-03-14 EP EP90400684A patent/EP0388298B1/fr not_active Expired - Lifetime
- 1990-03-14 HU HU901570A patent/HU206702B/hu not_active IP Right Cessation
- 1990-03-14 YU YU50590A patent/YU47430B/sh unknown
- 1990-03-14 DE DE69020199T patent/DE69020199T2/de not_active Expired - Fee Related
- 1990-03-14 DK DK90400684.8T patent/DK0388298T3/da active
- 1990-03-14 AT AT90400684T patent/ATE124039T1/de not_active IP Right Cessation
- 1990-03-15 CA CA002012223A patent/CA2012223A1/en not_active Abandoned
- 1990-03-15 PT PT93450A patent/PT93450B/pt not_active IP Right Cessation
- 1990-03-15 AU AU51375/90A patent/AU638437B2/en not_active Ceased
- 1990-03-16 JP JP2068014A patent/JPH075586B2/ja not_active Expired - Lifetime
- 1990-03-16 ES ES9000945A patent/ES2022006A6/es not_active Expired - Lifetime
- 1990-03-16 KR KR1019900003679A patent/KR940006595B1/ko not_active Expired - Fee Related
1991
- 1991-09-18 RU SU915001502A patent/RU2044735C1/ru active
1993
- 1993-09-21 AU AU47469/93A patent/AU648212B2/en not_active Ceased
1994
- 1994-02-03 US US08/191,153 patent/US5393758A/en not_active Expired - Fee Related
1995
- 1995-09-06 GR GR950402431T patent/GR3017304T3/el unknown

Also Published As

Publication number	Publication date
KR900014380A (ko)	1990-10-23
HU901570D0 (en)	1990-06-28
PT93450B (pt)	1996-07-31
EP0388298B1 (fr)	1995-06-21
US5393758A (en)	1995-02-28
DK0388298T3 (da)	1995-08-14
YU47430B (sh)	1995-03-27
RU2044735C1 (ru)	1995-09-27
PT93450A (pt)	1990-11-07
HU206702B (en)	1992-12-28
CA2012223A1 (en)	1990-09-16
HUT53643A (en)	1990-11-28
NO177302B (no)	1995-05-15
AU648212B2 (en)	1994-04-14
NO177302C (no)	1995-08-23
EP0388298A2 (fr)	1990-09-19
KR940006595B1 (ko)	1994-07-23
DE69020199D1 (de)	1995-07-27
AU5137590A (en)	1990-09-20
NO901171L (no)	1990-09-17
DE69020199T2 (de)	1995-12-14
ES2022006A6 (es)	1991-11-16
JPH075586B2 (ja)	1995-01-25
JPH02279683A (ja)	1990-11-15
ATE124039T1 (de)	1995-07-15
AU638437B2 (en)	1993-07-01
AU4746993A (en)	1993-12-02
EP0388298A3 (fr)	1991-07-31
NO901171D0 (no)	1990-03-13
YU50590A (sh)	1993-05-28

Publication	Publication Date	Title
PH25459A (en)	1991-07-01	Compound useful in the production of quinoline, naphthyridine carboxylic acids useful as antibacterials
IL111843A (en)	2000-02-29	Crystalline 3,4,4-trisubstituted piperidinyl-N-(3-phenylprop-2-YL) carboxylic acid derivatives pharmaceutical compositions containing them and processes for their preparation
AU1331588A (en)	1988-09-29	Method for treatment of alcohol abuse
DK449588D0 (da)	1988-08-11	4-oxo-1,4-dihydroquinolin-2-carboxylsyrederivat, dets anvendelse og fremstilling
HUT66596A (en)	1994-12-28	Process for preparing piperidine derivatives
GR3019796T3 (en)	1996-07-31	Quinolone carboxylic acid derivatives, process for their preparation and their use
EP0255908A3 (en)	1989-10-25	7-ûû3-(aminomethyl)-3-alkyl¨-1-pyrrolidinyl¨-quinoline-carboxylic acid-derivatives and pharmaceutical compositions containing them
GR3017304T3 (en)	1995-12-31	Derivatives of pyridone carboxylic acids substituted by an azetidine, their preparation and their use as medicines.
EP0287926A3 (en)	1990-05-09	Process for the preparation of quinoline carboxylic acids for parenteral application
NZ232207A (en)	1991-08-27	Dihydrobenz(c)acridine derivatives and pharmaceutical compositions
ZA895959B (en)	1990-04-25	New 6-fluoro-3,5-dihydroxy carboxylic acids and derivatives thereof,a process for the preparation thereof,the use thereof as medicinal agents,pharmaceutical products and intermediates
GR3020230T3 (en)	1996-09-30	Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments