GR3021971T3 - Imidazonaphthyridine derivatives - Google Patents

Imidazonaphthyridine derivatives

Info

Publication number: GR3021971T3
Authority: GR; Greece
Prior art keywords: lower alkyl; substituted; represents hydrogen; hydroxy; unsubstituted
Prior art date: 1990-06-01

Application number

GR960403401T

Other languages

English (en)

Inventor

Fumio Suzuki

Takeshi Kuroda

Shigeto Kitamura

Kenji Ohmori

Original Assignee

Kyowa Hakko Kogyo Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-06-01

Filing date

1996-12-11

Publication date

1997-03-31

1996-12-11 Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk

1997-03-31 Publication of GR3021971T3 publication Critical patent/GR3021971T3/el

Links

VFTLXHXYGQSOEN-UHFFFAOYSA-N 1h-imidazo[4,5-b][1,8]naphthyridine Chemical class C1=CN=C2NC3=NC=NC3=CC2=C1 VFTLXHXYGQSOEN-UHFFFAOYSA-N 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 6
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000003118 aryl group Chemical group 0.000 abstract 3
150000002431 hydrogen Chemical class 0.000 abstract 3
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
230000003266 anti-allergic effect Effects 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
125000001589 carboacyl group Chemical group 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
-1 mercapto, hydroxy Chemical group 0.000 abstract 1
125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Luminescent Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

GR960403401T 1990-06-01 1996-12-11 Imidazonaphthyridine derivatives GR3021971T3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP14346090		1990-06-01
JP33465790		1990-11-30

Publications (1)

Publication Number	Publication Date
GR3021971T3 true GR3021971T3 (en)	1997-03-31

Family

ID=26475184

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR960403401T GR3021971T3 (en)	1990-06-01	1996-12-11	Imidazonaphthyridine derivatives

Country Status (9)

Country	Link
US (3)	US5364859A (el)
EP (1)	EP0459505B1 (el)
JP (1)	JP3016905B2 (el)
AT (1)	ATE143661T1 (el)
CA (1)	CA2043715C (el)
DE (1)	DE69122427T2 (el)
DK (1)	DK0459505T3 (el)
ES (1)	ES2094772T3 (el)
GR (1)	GR3021971T3 (el)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69122427T2 (de) *	1990-06-01	1997-03-06	Kyowa Hakko Kogyo Kk	Imidazonaphthyridinderivate
US5281610A (en) *	1991-07-31	1994-01-25	Kyowa Hakko Kogyo Co., Ltd.	Condensed naphthyridine derivatives
JPH05194515A (ja) *	1991-07-31	1993-08-03	Kyowa Hakko Kogyo Co Ltd	縮合ナフチリジン誘導体
WO1993011127A1 (fr) *	1991-11-25	1993-06-10	Kyowa Hakko Kogyo Co., Ltd.	Derive d'imidazonaphtyridine
WO1994002481A1 (fr) *	1992-07-20	1994-02-03	Kyowa Hakko Kogyo Co., Ltd.	Derive d'imidazonaphtyridine
US6365231B2 (en)	1998-06-26	2002-04-02	Kabushiki Kaisha Toshiba	Ammonium halide eliminator, chemical vapor deposition system and chemical vapor deposition process
JP2000119271A (ja) *	1998-08-12	2000-04-25	Hokuriku Seiyaku Co Ltd	１ｈ―イミダゾピリジン誘導体
PL200923B1 (pl)	1999-08-21	2009-02-27	Nycomed Gmbh	Lek zawierający inhibitor PDE w połączeniu z agonistą receptoraß₂ -adrenergicznego oraz zastosowanie połączenia roflumilastu i salmeterolu
US6949247B2 (en)	2000-12-28	2005-09-27	Unilever Home & Personal Care Usa Division Of Conopco, Inc.	Stable skin care compositions containing a retinoid and a retinoid booster system
WO2002094321A1 (en)	2001-05-23	2002-11-28	Tanabe Seiyaku Co., Ltd.	Compositions for promoting healing of bone fracture
KR20040007583A (ko)	2001-05-23	2004-01-24	다나베 세이야꾸 가부시키가이샤	연골 질환의 재생치료용 조성물
US7087631B2 (en) *	2002-07-18	2006-08-08	Inotek Pharmaceuticals Corporation	Aryltetrazole compounds, and compositions thereof
JP2006522151A (ja)	2003-04-01	2006-09-28	アプライドリサーチシステムズエーアールエスホールディングナームロゼフェンノートシャップ	不妊症におけるホスホジエステラーゼ阻害剤
WO2007032466A1 (ja)	2005-09-15	2007-03-22	Aska Pharmaceutical Co., Ltd.	複素環化合物、その製造方法並びに用途
ES2550101T3 (es) *	2008-12-17	2015-11-04	Merck Patent Gmbh	Inhibidores de proteína quinasa de benzonaftiridinona tricíclica modificada con anillo C y su uso
WO2022143864A1 (zh) *	2020-12-31	2022-07-07	江苏先声药业有限公司	三环类化合物及用途
KR20240138099A (ko) *	2022-01-26	2024-09-20	쑤저우 젠하우스 바이오 컴퍼니 리미티드	Mtap 결실 암을 치료하기 위한 메티오닌 아데노실트랜스퍼라제 2a 억제제

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RO66801A (fr) *	1973-05-25	1979-08-15	Lepetit Spa	Procede pour obtenir des derives des triazoloizoquinolines
US4059584A (en) *	1974-08-07	1977-11-22	Pfizer	2-Acylamino-3-[3-(dialkylamino)propyl]imidazo[4,5-b]pyridines
ZA848968B (en) *	1983-11-18	1986-06-25	Riker Laboratories Inc	1h-imidazo(4,5-c)quinolines and 1h-imidazo(4,5-c)quinolin-4-amines
CA1271477A (en) *	1983-11-18	1990-07-10	John F. Gerster	1h-imidazo[4,5-c]quinolin-4-amines
IL73534A (en) *	1983-11-18	1990-12-23	Riker Laboratories Inc	1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
US4760073A (en) *	1986-04-11	1988-07-26	Schering Corporation	Aryl-substituted naphthyridine and pyridopyrazine derivatives, useful as anti-allergic agents
AU632461B2 (en) *	1987-07-22	1993-01-07	Schering Corporation	Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
DE69122427T2 (de) *	1990-06-01	1997-03-06	Kyowa Hakko Kogyo Kk	Imidazonaphthyridinderivate

1991
- 1991-05-31 DE DE69122427T patent/DE69122427T2/de not_active Expired - Fee Related
- 1991-05-31 ES ES91108908T patent/ES2094772T3/es not_active Expired - Lifetime
- 1991-05-31 DK DK91108908.4T patent/DK0459505T3/da active
- 1991-05-31 JP JP3129651A patent/JP3016905B2/ja not_active Expired - Fee Related
- 1991-05-31 AT AT91108908T patent/ATE143661T1/de not_active IP Right Cessation
- 1991-05-31 CA CA002043715A patent/CA2043715C/en not_active Expired - Fee Related
- 1991-05-31 EP EP91108908A patent/EP0459505B1/en not_active Expired - Lifetime
1992
- 1992-12-29 US US07/999,658 patent/US5364859A/en not_active Expired - Fee Related
1994
- 1994-05-12 US US08/241,631 patent/US5468756A/en not_active Expired - Fee Related
1995
- 1995-09-11 US US08/526,323 patent/US5536730A/en not_active Expired - Fee Related
1996
- 1996-12-11 GR GR960403401T patent/GR3021971T3/el unknown

Also Published As

Publication number	Publication date
DK0459505T3 (da)	1996-11-18
CA2043715C (en)	1997-01-07
US5364859A (en)	1994-11-15
EP0459505B1 (en)	1996-10-02
EP0459505A1 (en)	1991-12-04
JP3016905B2 (ja)	2000-03-06
CA2043715A1 (en)	1991-12-02
US5468756A (en)	1995-11-21
DE69122427T2 (de)	1997-03-06
ES2094772T3 (es)	1997-02-01
ATE143661T1 (de)	1996-10-15
US5536730A (en)	1996-07-16
JPH04226985A (ja)	1992-08-17
DE69122427D1 (de)	1996-11-07

Publication	Publication Date	Title
ES2094772T3 (es)	1997-02-01	Derivados de imidazonaftiridinas.
HU906029D0 (en)	1991-03-28	Process for the preparation of pleuromuthylyne derivatives
GB2248616B (en)	1994-06-15	Piperazine derivatives
PL309874A1 (en)	1996-02-05	Novel derivatives of pyrrolocarbasol, method of obtaining them and pharmaceutical composition containing such derivatives
NO882626D0 (no)	1988-06-15	Fremgangsmaate for fremstilling av farmakologisk aktive pyridin-derivater.
NO910804D0 (no)	1991-02-28	Substituerte beta-diketoner.
JPS6416781A (en)	1989-01-20	Cycloalkylamides of (8 beta)-1-alkyl-6- (substituted)ergoline
GB2254324B (en)	1994-06-22	Piperazine derivatives
ES2097295T3 (es)	1997-04-01	Preparacion de 2-(2-tienil)etilamina y sintesis de sus derivados de tieno(3,2-c)piridina.
ATE140919T1 (de)	1996-08-15	Indolderivate
DE69221006D1 (de)	1997-08-28	Mitomycinderivate
EP1251129A4 (en)	2003-03-05	PYRIMIDINE DERIVATIVES WITH ANTI-TUMOR EFFECT
ES2076995T3 (es)	1995-11-16	Procedimiento para preparar derivados de carbamato de lankacidina.