GR3033534T3 - Genetic therapy of diseases of the central nervous system with a cell-specific active substance which is dependent on the cell cycle - Google Patents

Genetic therapy of diseases of the central nervous system with a cell-specific active substance which is dependent on the cell cycle

Info

Publication number
GR3033534T3
GR3033534T3 GR20000401226T GR20000401226T GR3033534T3 GR 3033534 T3 GR3033534 T3 GR 3033534T3 GR 20000401226 T GR20000401226 T GR 20000401226T GR 20000401226 T GR20000401226 T GR 20000401226T GR 3033534 T3 GR3033534 T3 GR 3033534T3
Authority
GR
Greece
Prior art keywords
cell
active substance
pct
diseases
dependent
Prior art date
Application number
GR20000401226T
Other languages
English (en)
Inventor
Hans-Harald Sedlacek
Rolf Mueller
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26305524&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR3033534(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB9417366A external-priority patent/GB9417366D0/en
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of GR3033534T3 publication Critical patent/GR3033534T3/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/15Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/30Vector systems having a special element relevant for transcription being an enhancer not forming part of the promoter region
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/80Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85Vector systems having a special element relevant for transcription from vertebrates mammalian

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)
GR20000401226T 1994-08-26 2000-05-31 Genetic therapy of diseases of the central nervous system with a cell-specific active substance which is dependent on the cell cycle GR3033534T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9417366A GB9417366D0 (en) 1994-08-26 1994-08-26 Cell cycle regulated repressor and DNA element
GBGB9506466.3A GB9506466D0 (en) 1994-08-26 1995-03-29 Cell cycle regulated repressor and dna element
PCT/EP1995/003369 WO1996006939A1 (de) 1994-08-26 1995-08-25 Gentherapeutische behandlung von erkrankungen des zentralen nervensystems (zns) durch einen zellspezifischen, zellzyklusabhängigen wirkstoff

Publications (1)

Publication Number Publication Date
GR3033534T3 true GR3033534T3 (en) 2000-09-29

Family

ID=26305524

Family Applications (3)

Application Number Title Priority Date Filing Date
GR20000401227T GR3033535T3 (en) 1994-08-26 2000-05-31 Genetic therapy of vascular diseases with a cell-specific active substance which is dependent on the cell cycle
GR20000401226T GR3033534T3 (en) 1994-08-26 2000-05-31 Genetic therapy of diseases of the central nervous system with a cell-specific active substance which is dependent on the cell cycle
GR20010400847T GR3035994T3 (en) 1994-08-26 2001-06-06 Genetic therapy of tumours with an endothelium cell-specific active substance which is dependent on the cell cycle

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GR20000401227T GR3033535T3 (en) 1994-08-26 2000-05-31 Genetic therapy of vascular diseases with a cell-specific active substance which is dependent on the cell cycle

Family Applications After (1)

Application Number Title Priority Date Filing Date
GR20010400847T GR3035994T3 (en) 1994-08-26 2001-06-06 Genetic therapy of tumours with an endothelium cell-specific active substance which is dependent on the cell cycle

Country Status (18)

Country Link
US (3) US6214614B1 (el)
EP (4) EP0802985B1 (el)
JP (4) JPH10508188A (el)
KR (1) KR970705638A (el)
CN (1) CN1158144A (el)
AT (4) ATE229569T1 (el)
AU (4) AU711012B2 (el)
CA (4) CA2198080A1 (el)
DE (4) DE69529174T2 (el)
DK (4) DK0802985T3 (el)
ES (4) ES2190787T3 (el)
FI (2) FI970768A0 (el)
GB (1) GB9506466D0 (el)
GR (3) GR3033535T3 (el)
IL (1) IL115051A0 (el)
NZ (1) NZ291495A (el)
PT (4) PT802985E (el)
WO (3) WO1996006943A1 (el)

Families Citing this family (228)

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AU3387495A (en) 1996-03-22
DK0802985T3 (da) 2003-03-17
PT777739E (pt) 2000-07-31
EP0777740A1 (de) 1997-06-11
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FI970768L (fi) 1997-02-24
PT777740E (pt) 2000-07-31
AU3263995A (en) 1996-03-22
GR3033535T3 (en) 2000-09-29
AU690733B2 (en) 1998-04-30
DE59508144D1 (de) 2000-05-11
CA2198472A1 (en) 1996-03-07
ATE199741T1 (de) 2001-03-15
GB9506466D0 (en) 1995-05-17
US6358732B1 (en) 2002-03-19
ES2155137T3 (es) 2001-05-01
US6214614B1 (en) 2001-04-10
EP0804601A1 (de) 1997-11-05
AU3518595A (en) 1996-03-22
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EP0802985B1 (en) 2002-12-11
CN1158144A (zh) 1997-08-27
FI970674L (fi) 1997-04-21
JPH10506526A (ja) 1998-06-30
AU696593B2 (en) 1998-09-17
PT804601E (pt) 2001-06-29
CA2198473A1 (en) 1996-03-07
DE69529174D1 (de) 2003-01-23
WO1996006939A1 (de) 1996-03-07
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DK0777740T3 (da) 2000-08-14
ATE191506T1 (de) 2000-04-15
PT802985E (pt) 2003-04-30
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IL115051A0 (en) 1995-12-08
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AU711012B2 (en) 1999-10-07
EP0777739B1 (de) 2000-04-05
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DK0777739T3 (da) 2000-07-31
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EP0802985A1 (en) 1997-10-29
WO1996006943A1 (en) 1996-03-07
AU695458B2 (en) 1998-08-13
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GR3035994T3 (en) 2001-09-28
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EP0777740B1 (de) 2000-04-05
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WO1996006940A1 (de) 1996-03-07
DE59508145D1 (de) 2000-05-11
EP0777739A1 (de) 1997-06-11
KR970705638A (ko) 1997-10-09
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