HK42696A - Use of 2-amino-2,4,4-trimethylpentane salt of clavulanic acid in producing pharmaceutically acceptable salts of clavulanic acid - Google Patents

Use of 2-amino-2,4,4-trimethylpentane salt of clavulanic acid in producing pharmaceutically acceptable salts of clavulanic acid Download PDF

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Publication number
HK42696A
HK42696A HK42696A HK42696A HK42696A HK 42696 A HK42696 A HK 42696A HK 42696 A HK42696 A HK 42696A HK 42696 A HK42696 A HK 42696A HK 42696 A HK42696 A HK 42696A
Authority
HK
Hong Kong
Prior art keywords
clavulanic acid
amino
pharmaceutically acceptable
acceptable salts
producing pharmaceutically
Prior art date
Application number
HK42696A
Other languages
English (en)
Inventor
Krenmueller Franz
Summer Harald
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HK42696A publication Critical patent/HK42696A/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
HK42696A 1992-03-10 1996-03-14 Use of 2-amino-2,4,4-trimethylpentane salt of clavulanic acid in producing pharmaceutically acceptable salts of clavulanic acid HK42696A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0047292A AT400033B (de) 1992-03-10 1992-03-10 Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben

Publications (1)

Publication Number Publication Date
HK42696A true HK42696A (en) 1996-03-22

Family

ID=3491521

Family Applications (1)

Application Number Title Priority Date Filing Date
HK42696A HK42696A (en) 1992-03-10 1996-03-14 Use of 2-amino-2,4,4-trimethylpentane salt of clavulanic acid in producing pharmaceutically acceptable salts of clavulanic acid

Country Status (21)

Country Link
US (4) US20010036940A1 (de)
JP (2) JP2817563B2 (de)
CN (3) CN1045604C (de)
AT (1) AT400033B (de)
AU (1) AU659282B2 (de)
CH (1) CH685054A5 (de)
CY (1) CY1995A (de)
DE (1) DE4307422B4 (de)
DK (1) DK26093A (de)
ES (1) ES2058029B1 (de)
FI (1) FI101965B (de)
FR (1) FR2688506B1 (de)
GB (1) GB2264944B (de)
GR (1) GR1002329B (de)
HK (1) HK42696A (de)
IE (1) IE70926B1 (de)
IT (1) IT1261213B (de)
NL (1) NL9300430A (de)
NO (1) NO301372B1 (de)
SE (1) SE508043C2 (de)
TW (1) TW364907B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT399155B (de) * 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) * 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
KR100200239B1 (ko) * 1992-10-21 1999-06-15 김충환 클라불란산 칼륨염의 제조방법
DK0658558T3 (da) 1993-11-17 2001-04-17 Biochemie Gmbh Adskillelse af cephalosporinisomere
GB9426261D0 (en) * 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts
NZ301765A (en) * 1995-02-25 1999-10-28 Spurcourt Ltd Clavulanic acid salts with a benzhydrylamine
KR100200242B1 (ko) * 1995-05-16 1999-06-15 김충환 클라불란산염의 제조 방법
AT403375B (de) * 1995-11-15 1998-01-26 Biochemie Gmbh Verfahren zur fällung von alkalisalzen der clavulansäure
WO2000004028A1 (en) * 1998-07-16 2000-01-27 Dsm N.V. Improved process for the preparation of salts and esters of clavulanic acid
CN1209099C (zh) * 1999-04-01 2005-07-06 Dsm公司 结晶化附聚物
CA2408853C (en) * 2000-05-13 2012-01-10 Smithkline Beecham P.L.C. Process
EP1933857A2 (de) * 2005-09-07 2008-06-25 Jennerex Biotherapeutics ULC Systemische behandlung von metastasierten und/oder systemisch dissemierten tumoren mit gm-csf-exprimierenden pockenviren
JP7028064B2 (ja) 2018-05-30 2022-03-02 横河電機株式会社 機器保全装置、機器保全方法、機器保全プログラム及び記録媒体
JP2023533544A (ja) 2020-07-10 2023-08-03 カーボン クリーン ソリューションズ リミテッド 低位熱を使用して溶媒から二酸化炭素を除去するための方法およびシステム

Family Cites Families (34)

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Publication number Priority date Publication date Assignee Title
US3288800A (en) * 1962-05-29 1966-11-29 Squibb & Sons Inc Schiff's bases of 6-amino-penicillanic acid and purification of 6-aminopenicillanic acid by the use thereof
GB1508977A (en) 1974-04-20 1978-04-26 Beecham Group Ltd Beta-lactam antibiotic from streptomyces clavuligerus
IE41109B1 (en) * 1974-04-20 1979-10-24 Beecham Group Ltd Novel -lactam antibiotic from streptomyces clavuligerus
US4110165A (en) * 1974-04-20 1978-08-29 Beecham Group Limited Process for the production of clavulanic acid
GB1543563A (en) 1975-02-07 1979-04-04 Glaxo Lab Ltd Beta-lactam antibiotic in purified form
US4144242A (en) * 1975-02-07 1979-03-13 Glaxo Laboratories Limited Process for the purification of clavulanic acid
GB1561395A (en) 1976-02-26 1980-02-20 Beecham Group Ltd -lactam antibiotic
GB1578739A (en) * 1976-07-23 1980-11-05 Beecham Group Ltd Amine salts of clavulanic acid methods for their preparation and compositions containing them
GB2003863B (en) 1977-09-01 1982-03-31 Beecham Group Ltd Chemical process
DE2861607D1 (en) 1977-11-26 1982-03-11 Beecham Group Plc Derivatives of clavulanic acid and pharmaceutical compositions containing them
BE862211A (fr) * 1977-12-22 1978-06-22 Beecham Group Ltd Agents antibacteriens
US4454069A (en) * 1979-08-24 1984-06-12 Beecham Group Limited Clavulanic acid salts and their preparation from the tertiary butyl amine salt
DE3063683D1 (en) * 1979-08-24 1983-07-14 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
NZ213963A (en) 1984-10-27 1989-01-06 Antibioticos Sa Production of clavulanic acid
GB8618888D0 (en) * 1986-08-01 1986-09-10 Davy Mckee Ltd Process
US5679789A (en) * 1987-01-29 1997-10-21 Beecham Group, P.L.C. Pharmaceutical compositions comprising potassium clavulanate and methods of using them
PT86631B (pt) 1987-01-29 1992-01-31 Beecham Group Plc Processo para a preparacao de uma nova forma cristalina de clavulanato de potassio
ES2010143A6 (es) * 1989-03-01 1989-10-16 Pharma Mar S A Pharmar Un nuevo procedimiento de obtencion del acido z(2r,5r)-3-(2-hiadroxietiliden)-7- oxo-4-oxa-1-azabiciclo(3,2,0) -heptano-2-carboxilico y de sales estares farmaceutiacamente aceptables del mismo,a partir de caldos de fermentacion de streptomyces, sp.
US5210296A (en) * 1990-11-19 1993-05-11 E. I. Du Pont De Nemours And Company Recovery of lactate esters and lactic acid from fermentation broth
AT399155B (de) * 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
SI9200139A (en) * 1992-07-08 1994-03-31 Lek Tovarna Farmacevtskih New inclusion complex of clavulanic acid with hydrophylyc and hydropholyc beta-cyclodextrin derivates for production of them
KR100200239B1 (ko) 1992-10-21 1999-06-15 김충환 클라불란산 칼륨염의 제조방법
GB9401969D0 (en) 1994-02-02 1994-03-30 Smithkline Beecham Plc Process
SI9400107A (en) 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
NZ301765A (en) * 1995-02-25 1999-10-28 Spurcourt Ltd Clavulanic acid salts with a benzhydrylamine
GB2298201B (en) 1995-02-25 1997-05-28 Spurcourt Ltd Clavulanic acid salts
SI9500074A (en) 1995-03-10 1996-10-31 Lek Tovarna Farmacevtskih Process for preparation of alkani salts of clavulanic acid.
SI9500134B (sl) 1995-04-20 2004-04-30 Lek, Postopek za pripravo čistih alkalijskih soli klavulanske kisline
KR100200242B1 (ko) 1995-05-16 1999-06-15 김충환 클라불란산염의 제조 방법
GB9515809D0 (en) 1995-08-02 1995-10-04 Smithkline Beecham Plc Process
SI9500265A1 (en) 1995-08-28 1997-02-28 Lek Tovarna Farmacevtskih Process for purification of the aqueous fermented broth filtrate of streptomyces sp. p 6621 ferm p 2804 by ultrafiltration
US6414142B1 (en) 1996-06-13 2002-07-02 Smithkline Beecham Corporation Process for preparing potassium clavulanate
CA2271847A1 (en) 1996-11-11 1998-05-22 Gist-Brocades B.V. Process for the preparation of salts and esters of clavulanic acid

Also Published As

Publication number Publication date
IE70926B1 (en) 1997-01-15
IT1261213B (it) 1996-05-09
NO930829D0 (no) 1993-03-08
DK26093D0 (da) 1993-03-09
US20030022882A1 (en) 2003-01-30
GB9304704D0 (en) 1993-04-28
CN1145906A (zh) 1997-03-26
SE9300758D0 (sv) 1993-03-08
FR2688506A1 (fr) 1993-09-17
CN1045604C (zh) 1999-10-13
GB2264944A (en) 1993-09-15
AU659282B2 (en) 1995-05-11
USH2158H1 (en) 2006-06-06
ES2058029B1 (es) 1995-05-01
ES2058029A1 (es) 1994-10-16
NL9300430A (nl) 1993-10-01
FI101965B1 (fi) 1998-09-30
TW364907B (en) 1999-07-21
GB2264944B (en) 1995-09-06
IE930172A1 (en) 1993-09-22
ATA47292A (de) 1995-01-15
CN1150153A (zh) 1997-05-21
CH685054A5 (de) 1995-03-15
AU3407093A (en) 1993-09-16
SE9300758L (sv) 1993-09-11
NO930829L (no) 1993-09-13
DK26093A (da) 1993-09-11
ITRM930147A0 (it) 1993-03-10
CY1995A (en) 1997-09-05
AT400033B (de) 1995-09-25
FR2688506B1 (fr) 1995-06-23
FI931032A0 (fi) 1993-03-09
FI931032L (fi) 1993-09-11
DE4307422A1 (de) 1993-09-30
GR930100090A (el) 1993-11-30
US20010036940A1 (en) 2001-11-01
US20030203886A1 (en) 2003-10-30
NO301372B1 (no) 1997-10-20
ITRM930147A1 (it) 1994-09-10
GR1002329B (el) 1996-05-15
US20020072513A1 (en) 2002-06-13
DE4307422B4 (de) 2004-11-25
SE508043C2 (sv) 1998-08-17
JPH0641143A (ja) 1994-02-15
CN1079743A (zh) 1993-12-22
FI101965B (fi) 1998-09-30
JP2817563B2 (ja) 1998-10-30
JPH1067785A (ja) 1998-03-10

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Legal Events

Date Code Title Description
PF Patent in force
AS Change of ownership

Owner name: SANDOZ AG

Free format text: FORMER OWNER(S): SANDOZ GMBH

CHPA Change of a particular in the register (except of change of ownership)
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20100308