HRP20000731A2 - Aryl fused azapolycyclic compounds - Google Patents

Aryl fused azapolycyclic compounds Download PDF

Info

Publication number
HRP20000731A2
HRP20000731A2 HR20000731A HRP20000731A HRP20000731A2 HR P20000731 A2 HRP20000731 A2 HR P20000731A2 HR 20000731 A HR20000731 A HR 20000731A HR P20000731 A HRP20000731 A HR P20000731A HR P20000731 A2 HRP20000731 A2 HR P20000731A2
Authority
HR
Croatia
Prior art keywords
trideca
triene
aza
tricyclo
alkyl
Prior art date
Application number
HR20000731A
Other languages
English (en)
Croatian (hr)
Inventor
Jotham Wadsworth Coe
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of HRP20000731A2 publication Critical patent/HRP20000731A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
HR20000731A 1998-04-29 1999-04-08 Aryl fused azapolycyclic compounds HRP20000731A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8355698P 1998-04-29 1998-04-29
PCT/IB1999/000617 WO1999055680A1 (en) 1998-04-29 1999-04-08 Aryl fused azapolycyclic compounds

Publications (1)

Publication Number Publication Date
HRP20000731A2 true HRP20000731A2 (en) 2001-06-30

Family

ID=22179102

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20000731A HRP20000731A2 (en) 1998-04-29 1999-04-08 Aryl fused azapolycyclic compounds

Country Status (41)

Country Link
US (3) US6462035B1 (de)
EP (1) EP1076650B1 (de)
JP (1) JP2002513007A (de)
KR (1) KR100420423B1 (de)
CN (1) CN1144787C (de)
AP (1) AP1154A (de)
AR (1) AR018596A1 (de)
AT (1) ATE258921T1 (de)
AU (1) AU749831B2 (de)
BG (1) BG64556B1 (de)
BR (1) BR9910058A (de)
CA (1) CA2330576A1 (de)
CO (1) CO5021124A1 (de)
DE (1) DE69914594T2 (de)
DK (1) DK1076650T3 (de)
DZ (1) DZ2778A1 (de)
EA (1) EA003669B1 (de)
ES (1) ES2213354T3 (de)
GT (1) GT199900059A (de)
HR (1) HRP20000731A2 (de)
HU (1) HUP0103340A3 (de)
ID (1) ID26700A (de)
IL (1) IL138917A0 (de)
IS (1) IS5649A (de)
MA (1) MA26623A1 (de)
MY (1) MY133474A (de)
NO (1) NO317300B1 (de)
NZ (1) NZ507035A (de)
OA (1) OA11506A (de)
PA (1) PA8471301A1 (de)
PE (1) PE20000435A1 (de)
PL (1) PL344010A1 (de)
PT (1) PT1076650E (de)
SK (1) SK15952000A3 (de)
TN (1) TNSN99080A1 (de)
TR (1) TR200003122T2 (de)
UA (1) UA61991C2 (de)
UY (1) UY25636A1 (de)
WO (1) WO1999055680A1 (de)
YU (1) YU64400A (de)
ZA (1) ZA992971B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6605610B1 (en) * 1997-12-31 2003-08-12 Pfizer Inc Aryl fused azapolycyclic compounds
PT1044189E (pt) 1997-12-31 2008-04-22 Pfizer Prod Inc Compostos azapolicíclicos condensados com arilo
US20010036943A1 (en) * 2000-04-07 2001-11-01 Coe Jotham W. Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines
PT1383733E (pt) 2001-04-20 2008-04-15 Pfizer Prod Inc Processo para a preparação de indenos 1,3-substituídos e compostos azapolicíclicos fundidos com arilo
PL370549A1 (en) * 2001-10-31 2005-05-30 Pfizer Products Inc. Nicotinic acetylcholine receptor agonists in the treatment of restless legs syndrome
DE60228478D1 (de) 2001-11-30 2008-10-02 Pfizer Prod Inc Aryl-annellierte azapolyzyklische verbindungen
US20060089400A1 (en) * 2002-05-03 2006-04-27 The Vernalis Group Of Companies Novel spiro ketone and carboxylic acid derivatives as specific inhibitors for (po3h2) ser/(po3h2)thr-pro-specific peptidyl-prolylcis/trans-isomerases
US20040224963A1 (en) * 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal
US20040224962A1 (en) * 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the treatment of obesity or to facilitate or promote weight loss
ES2331245T3 (es) * 2003-07-21 2009-12-28 Pfizer Products Inc. Compuestos azapoliciclicos condensados con heteroarilo que reducen la adiccion a la nicotina.
MXPA06000892A (es) * 2003-07-21 2006-03-30 Pfizer Prod Inc Compuestos azapoliciclicos arilo fusionados.
US20050043407A1 (en) * 2003-08-22 2005-02-24 Pfizer Inc Pharmaceutical composition for the prevention and treatment of addiction in a mammal
CA2591330A1 (en) * 2004-12-07 2006-06-15 Pfizer Products Inc. 1, 2, 3, 3a, 8, 8a-hexahydro-2, 7a-diada-cyclopenta [a] inden-7-one derivatives which bind to neuronal nicotinic acetylcholine specific receptor sites and are useful in modulatingcholinergic function and in the treatment of addictive disorders
US20060210497A1 (en) * 2005-03-18 2006-09-21 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Novel resorcinol derivatives
US20060210498A1 (en) 2005-03-18 2006-09-21 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Novel resorcinol derivatives for skin
DE102005061426A1 (de) * 2005-12-22 2007-07-05 Grünenthal GmbH Substituierte tricyclische Piperidon-Derivate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3687937A (en) * 1970-06-23 1972-08-29 Us Of America The 1,5-methano-3-benzazocine derivatives
JPS4914473A (de) * 1972-06-09 1974-02-07
JPS4924968A (de) * 1972-07-01 1974-03-05

Also Published As

Publication number Publication date
US20030008890A1 (en) 2003-01-09
AP1154A (en) 2003-03-27
DZ2778A1 (fr) 2005-04-23
AP9901524A0 (en) 1999-06-30
TR200003122T2 (tr) 2001-03-21
EA200000996A1 (ru) 2001-06-25
PA8471301A1 (es) 2000-09-29
DK1076650T3 (da) 2004-05-24
MY133474A (en) 2007-11-30
ID26700A (id) 2001-02-01
HUP0103340A3 (en) 2002-10-28
SK15952000A3 (sk) 2002-06-04
CO5021124A1 (es) 2001-03-27
AU749831B2 (en) 2002-07-04
HUP0103340A2 (hu) 2002-02-28
PT1076650E (pt) 2004-05-31
US6462035B1 (en) 2002-10-08
YU64400A (sh) 2003-01-31
AU2951699A (en) 1999-11-16
KR20010043143A (ko) 2001-05-25
ZA992971B (en) 2000-10-30
DE69914594T2 (de) 2004-12-09
BG64556B1 (bg) 2005-07-29
NO317300B1 (no) 2004-10-04
OA11506A (en) 2004-05-14
CN1298394A (zh) 2001-06-06
ES2213354T3 (es) 2004-08-16
EA003669B1 (ru) 2003-08-28
AR018596A1 (es) 2001-11-28
CN1144787C (zh) 2004-04-07
GT199900059A (es) 2000-10-11
CA2330576A1 (en) 1999-11-04
BR9910058A (pt) 2000-12-26
PE20000435A1 (es) 2000-05-26
US6706702B2 (en) 2004-03-16
NZ507035A (en) 2003-05-30
EP1076650B1 (de) 2004-02-04
WO1999055680A1 (en) 1999-11-04
TNSN99080A1 (fr) 2005-11-10
IS5649A (is) 2000-09-29
UA61991C2 (en) 2003-12-15
BG104983A (en) 2001-09-28
ATE258921T1 (de) 2004-02-15
PL344010A1 (en) 2001-09-24
US20040167149A1 (en) 2004-08-26
MA26623A1 (fr) 2004-12-20
HK1036453A1 (en) 2002-01-04
JP2002513007A (ja) 2002-05-08
IL138917A0 (en) 2001-11-25
US7122534B2 (en) 2006-10-17
NO20005397L (no) 2000-10-26
NO20005397D0 (no) 2000-10-26
UY25636A1 (es) 2000-02-23
KR100420423B1 (ko) 2004-03-04
DE69914594D1 (de) 2004-03-11
EP1076650A1 (de) 2001-02-21

Similar Documents

Publication Publication Date Title
US20030130261A1 (en) Aryl fused azapolycyclic compounds
KR100551183B1 (ko) 1,3-치환 인덴 및 아릴-융합 아자폴리시클릭 화합물의제조 방법
EP1076650B1 (de) Aryl-annellierte azapolycyclische verbindungen
HRP20000445A2 (en) Aryl fused azapolycyclic compounds
JP2023168623A (ja) シグマ－２受容体の新規調節物質およびその使用方法
AU2002234836A1 (en) Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic compounds
JP4493648B2 (ja) オピオイド受容体拮抗薬としての２‐アザビシクロ（３．３．１）ノナン誘導体
MXPA00010540A (en) Aryl fused azapolycyclic compounds
CZ20003972A3 (cs) Aryl-arelované azapolycyklické sloučeniny

Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
OBST Application withdrawn