HRP20030654A2 - Method for purifying 20(s)-camptothecin - Google Patents

Method for purifying 20(s)-camptothecin Download PDF

Info

Publication number
HRP20030654A2
HRP20030654A2 HR20030654A HRP20030654A HRP20030654A2 HR P20030654 A2 HRP20030654 A2 HR P20030654A2 HR 20030654 A HR20030654 A HR 20030654A HR P20030654 A HRP20030654 A HR P20030654A HR P20030654 A2 HRP20030654 A2 HR P20030654A2
Authority
HR
Croatia
Prior art keywords
camptothecin
vinyl
crystals
formula
mixture
Prior art date
Application number
HR20030654A
Other languages
English (en)
Croatian (hr)
Inventor
Sobotta Rainer
Rapp Armin
Original Assignee
Boehringer Ingelheim Pharma Gmbh & Co.Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma Gmbh & Co.Kg filed Critical Boehringer Ingelheim Pharma Gmbh & Co.Kg
Publication of HRP20030654A2 publication Critical patent/HRP20030654A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
HR20030654A 2001-02-15 2002-02-09 Method for purifying 20(s)-camptothecin HRP20030654A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10106969A DE10106969C1 (de) 2001-02-15 2001-02-15 Verfahren zur Reinigung und zur Herstellung von 20(S)-Camptothecin
PCT/EP2002/001375 WO2002064597A2 (de) 2001-02-15 2002-02-09 Verfahren zur reinigung von 20(s)-camptothecin

Publications (1)

Publication Number Publication Date
HRP20030654A2 true HRP20030654A2 (en) 2005-06-30

Family

ID=7674093

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20030654A HRP20030654A2 (en) 2001-02-15 2002-02-09 Method for purifying 20(s)-camptothecin

Country Status (26)

Country Link
EP (1) EP1362051B1 (cs)
JP (1) JP4467884B2 (cs)
KR (1) KR100813087B1 (cs)
CN (1) CN1228340C (cs)
AT (1) ATE301124T1 (cs)
AU (1) AU2002244711B2 (cs)
BG (1) BG108064A (cs)
BR (1) BR0207261A (cs)
CA (1) CA2435372C (cs)
CZ (1) CZ300671B6 (cs)
DE (2) DE10106969C1 (cs)
EA (1) EA005618B1 (cs)
EE (1) EE05131B1 (cs)
ES (1) ES2246389T3 (cs)
HR (1) HRP20030654A2 (cs)
HU (1) HUP0303030A3 (cs)
IL (2) IL157148A0 (cs)
MX (1) MXPA03007194A (cs)
NO (1) NO328106B1 (cs)
NZ (1) NZ528039A (cs)
PL (1) PL202135B1 (cs)
RS (1) RS50496B (cs)
SK (1) SK10192003A3 (cs)
UA (1) UA74874C2 (cs)
WO (1) WO2002064597A2 (cs)
ZA (1) ZA200305364B (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI396690B (zh) * 2006-04-27 2013-05-21 Yakult Honsha Kk 喜樹鹼衍生物的製造方法
CN102046634B (zh) * 2008-05-29 2013-04-24 日本迈科洛生物制药有限公司 喜树碱衍生物的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527913A (en) * 1993-02-25 1996-06-18 The Stehlin Foundation For Cancer Research Methods for purifying camptothecin compounds

Also Published As

Publication number Publication date
ZA200305364B (en) 2004-04-28
CZ20032211A3 (cs) 2003-12-17
ATE301124T1 (de) 2005-08-15
BG108064A (bg) 2005-04-30
EE05131B1 (et) 2009-02-16
CZ300671B6 (cs) 2009-07-15
WO2002064597A3 (de) 2002-10-24
CN1228340C (zh) 2005-11-23
NO20033614L (no) 2003-08-14
NO328106B1 (no) 2009-12-07
PL202135B1 (pl) 2009-06-30
CA2435372C (en) 2010-04-20
HUP0303030A2 (hu) 2003-12-29
EA005618B1 (ru) 2005-04-28
RS50496B (sr) 2010-03-02
IL157148A (en) 2008-08-07
EP1362051A2 (de) 2003-11-19
PL362128A1 (en) 2004-10-18
BR0207261A (pt) 2004-06-15
ES2246389T3 (es) 2006-02-16
EA200300837A1 (ru) 2003-12-25
CA2435372A1 (en) 2002-08-22
AU2002244711B2 (en) 2007-05-31
UA74874C2 (en) 2006-02-15
SK10192003A3 (sk) 2004-01-08
DE10106969C1 (de) 2002-10-02
HK1064092A1 (en) 2005-01-21
EP1362051B1 (de) 2005-08-03
EE200300389A (et) 2003-12-15
IL157148A0 (en) 2004-02-08
NZ528039A (en) 2006-02-24
HUP0303030A3 (en) 2004-11-29
JP2004521909A (ja) 2004-07-22
CN1491228A (zh) 2004-04-21
KR100813087B1 (ko) 2008-03-17
DE50203824D1 (de) 2005-09-08
JP4467884B2 (ja) 2010-05-26
NO20033614D0 (no) 2003-08-14
KR20030076674A (ko) 2003-09-26
WO2002064597A2 (de) 2002-08-22
MXPA03007194A (es) 2003-12-04
YU61403A (sh) 2006-05-25

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A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
ODBC Application rejected