HRP20040871A2 - Substituted amino isoxazoline derivatives and their use as anti-depressants - Google Patents

Substituted amino isoxazoline derivatives and their use as anti-depressants

Info

Publication number: HRP20040871A2
Authority: HR; Croatia
Prior art keywords: alkyl; group; radical; mono; formula
Prior art date: 2002-04-02

Application number

HR20040871A

Other languages

English (en)

Croatian (hr)

Inventor

Jose

Manuel

Margaretha

Ana

Original Assignee

Janssen Pharmaceutica N.V.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-02

Filing date

2003-03-27

Publication date

2005-04-30

2003-03-27 Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.

2005-04-30 Publication of HRP20040871A2 publication Critical patent/HRP20040871A2/hr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Obesity (AREA)
Hematology (AREA)
Diabetes (AREA)
Hospice & Palliative Care (AREA)
Child & Adolescent Psychology (AREA)
Anesthesiology (AREA)
Addiction (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

HR20040871A 2002-04-02 2003-03-27 Substituted amino isoxazoline derivatives and their use as anti-depressants HRP20040871A2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP02076239		2002-04-02
PCT/EP2003/003245 WO2003082878A1 (en)	2002-04-02	2003-03-27	Substituted amino isoxazoline derivatives and their use as anti-depressants.

Publications (1)

Publication Number	Publication Date
HRP20040871A2 true HRP20040871A2 (en)	2005-04-30

Family

ID=28459528

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20040871A HRP20040871A2 (en)	2002-04-02	2003-03-27	Substituted amino isoxazoline derivatives and their use as anti-depressants

Country Status (24)

Country	Link
US (1)	US7265103B2 (pl)
EP (1)	EP1492796B1 (pl)
JP (1)	JP4580653B2 (pl)
KR (1)	KR20040093061A (pl)
CN (1)	CN100349897C (pl)
AR (1)	AR039207A1 (pl)
AT (1)	ATE372342T1 (pl)
BR (1)	BR0308309A (pl)
CA (1)	CA2480113C (pl)
DE (1)	DE60316134T2 (pl)
DK (1)	DK1492796T3 (pl)
EA (1)	EA008189B1 (pl)
ES (1)	ES2292949T3 (pl)
HK (1)	HK1080072A1 (pl)
HR (1)	HRP20040871A2 (pl)
IL (2)	IL164341A0 (pl)
MX (1)	MXPA04008626A (pl)
NO (1)	NO20044645L (pl)
NZ (1)	NZ536109A (pl)
PL (1)	PL211708B1 (pl)
PT (1)	PT1492796E (pl)
TW (1)	TWI286138B (pl)
WO (1)	WO2003082878A1 (pl)
ZA (1)	ZA200407904B (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW200409777A (en)	2002-08-12	2004-06-16	Janssen Pharmaceutica Nv	C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants
JP4478570B2 (ja) *	2002-08-21	2010-06-09	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	Ｃ６−およびｃ９−置換’４，３−ｃ！イソキサゾリン誘導体およびそれらの抗鬱薬としての使用
ES2331144T3 (es)	2004-11-26	2009-12-22	Janssen Pharmaceutica Nv	Derivados de isoxazolina-indol con actividad antipsicotica y ansiolitica mejorada.
AU2008270444A1 (en) *	2007-07-03	2009-01-08	F. Hoffmann-La Roche Ag	4-imidazolines and their use as antidepressants
RS53416B (sr)	2009-03-10	2014-12-31	Takeda Pharmaceutical Company Limited	Derivati benzofurana
US20130062732A1 (en)	2011-09-08	2013-03-14	International Business Machines Corporation	Interconnect structures with functional components and methods for fabrication
CN105801510A (zh) *	2016-04-08	2016-07-27	李勇	一种治疗抑郁症的药物组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2055011T3 (es)	1988-09-19	1994-08-16	Akzo Nv	Un procedimiento para la preparacion de derivados de tetrahidronaftaleno e indano.
EP0874833A1 (en) *	1996-01-05	1998-11-04	Hoechst Marion Roussel, Inc.	4,5-dihydronaphth 1,2-c]isoxazoles and derivatives thereof having cns activity
US6187774B1 (en) *	1996-03-04	2001-02-13	Yoshitomi Pharmaceutical Industries, Ltd.	Fused heterocyclic compounds and pharmaceutical applications thereof
CA2437505C (en) *	2001-02-21	2010-02-09	Janssen Pharmaceutica N.V.	Isoxazoline derivatives as anti-depressants
TW200409777A (en) *	2002-08-12	2004-06-16	Janssen Pharmaceutica Nv	C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants
JP4478570B2 (ja) *	2002-08-21	2010-06-09	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	Ｃ６−およびｃ９−置換’４，３−ｃ！イソキサゾリン誘導体およびそれらの抗鬱薬としての使用

2003
- 2003-03-27 AT AT03714897T patent/ATE372342T1/de not_active IP Right Cessation
- 2003-03-27 PT PT03714897T patent/PT1492796E/pt unknown
- 2003-03-27 IL IL16434103A patent/IL164341A0/xx unknown
- 2003-03-27 JP JP2003580343A patent/JP4580653B2/ja not_active Expired - Fee Related
- 2003-03-27 NZ NZ536109A patent/NZ536109A/en unknown
- 2003-03-27 DK DK03714897T patent/DK1492796T3/da active
- 2003-03-27 WO PCT/EP2003/003245 patent/WO2003082878A1/en not_active Ceased
- 2003-03-27 HK HK05112213.1A patent/HK1080072A1/zh unknown
- 2003-03-27 EP EP03714897A patent/EP1492796B1/en not_active Expired - Lifetime
- 2003-03-27 MX MXPA04008626A patent/MXPA04008626A/es active IP Right Grant
- 2003-03-27 EA EA200401297A patent/EA008189B1/ru not_active IP Right Cessation
- 2003-03-27 US US10/510,220 patent/US7265103B2/en not_active Expired - Lifetime
- 2003-03-27 PL PL371630A patent/PL211708B1/pl unknown
- 2003-03-27 CA CA2480113A patent/CA2480113C/en not_active Expired - Fee Related
- 2003-03-27 HR HR20040871A patent/HRP20040871A2/hr not_active Application Discontinuation
- 2003-03-27 BR BR0308309-8A patent/BR0308309A/pt not_active IP Right Cessation
- 2003-03-27 CN CNB038074192A patent/CN100349897C/zh not_active Expired - Fee Related
- 2003-03-27 ES ES03714897T patent/ES2292949T3/es not_active Expired - Lifetime
- 2003-03-27 DE DE60316134T patent/DE60316134T2/de not_active Expired - Lifetime
- 2003-03-27 KR KR10-2004-7012757A patent/KR20040093061A/ko not_active Ceased
- 2003-04-01 TW TW092107328A patent/TWI286138B/zh not_active IP Right Cessation
- 2003-04-01 AR ARP030101126A patent/AR039207A1/es unknown
2004
- 2004-09-28 IL IL164341A patent/IL164341A/en not_active IP Right Cessation
- 2004-09-30 ZA ZA200407904A patent/ZA200407904B/xx unknown
- 2004-10-27 NO NO20044645A patent/NO20044645L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CN100349897C (zh)	2007-11-21
HK1080072A1 (zh)	2006-04-21
ZA200407904B (en)	2005-10-20
IL164341A0 (en)	2005-12-18
MXPA04008626A (es)	2004-12-06
AR039207A1 (es)	2005-02-09
CN1642960A (zh)	2005-07-20
NZ536109A (en)	2006-06-30
NO20044645L (no)	2004-10-27
TWI286138B (en)	2007-09-01
CA2480113C (en)	2012-04-24
IL164341A (en)	2009-06-15
PT1492796E (pt)	2007-11-16
DE60316134T2 (de)	2008-05-29
BR0308309A (pt)	2004-12-28
CA2480113A1 (en)	2003-10-09
DE60316134D1 (de)	2007-10-18
EA200401297A1 (ru)	2005-02-24
WO2003082878A1 (en)	2003-10-09
TW200406414A (en)	2004-05-01
PL211708B1 (pl)	2012-06-29
EP1492796B1 (en)	2007-09-05
JP2005522469A (ja)	2005-07-28
AU2003219111A1 (en)	2003-10-13
EP1492796A1 (en)	2005-01-05
EA008189B1 (ru)	2007-04-27
US7265103B2 (en)	2007-09-04
ES2292949T3 (es)	2008-03-16
DK1492796T3 (da)	2007-12-03
ATE372342T1 (de)	2007-09-15
US20050222125A1 (en)	2005-10-06
JP4580653B2 (ja)	2010-11-17
KR20040093061A (ko)	2004-11-04
PL371630A1 (pl)	2005-06-27

Legal Events

Date	Code	Title	Description
2005-04-30	A1OB	Publication of a patent application
2005-10-12	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2007-02-17	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20070217 Year of fee payment: 5
2009-01-13	OBST	Application withdrawn

Publication	Publication Date	Title
AU2002244717B2 (en)	2007-07-19	Isoxazoline derivatives as anti-depressants
HRP20040871A2 (en)	2005-04-30	Substituted amino isoxazoline derivatives and their use as anti-depressants
CA2494557C (en)	2011-10-18	Fused heterocyclic isoxazoline derivatives and their use as anti-depressants
CA2495058C (en)	2012-01-03	C6- and c9-substituted isoxazoline derivatives and their use as anti-depressants
JP4681295B2 (ja)	2011-05-11	Ｃ−置換三環式イソオキサゾリン誘導体及び抗−うつ薬としてのそれらの使用
JP2008521771A (ja)	2008-06-26	改良された抗精神病活性および抗不安症活性を有するイソキサゾリン−インドール誘導体
AU2003219111B2 (en)	2008-11-27	Substituted amino isoxazoline derivatives and their use as anti-depressants