NO20044645L - Substituerte amino-isoksazolinderivater og deres anvendelse som antidepressive midler - Google Patents
Substituerte amino-isoksazolinderivater og deres anvendelse som antidepressive midlerInfo
- Publication number
- NO20044645L NO20044645L NO20044645A NO20044645A NO20044645L NO 20044645 L NO20044645 L NO 20044645L NO 20044645 A NO20044645 A NO 20044645A NO 20044645 A NO20044645 A NO 20044645A NO 20044645 L NO20044645 L NO 20044645L
- Authority
- NO
- Norway
- Prior art keywords
- substituted amino
- isoxazoline derivatives
- antidepressants
- formula
- optionally substituted
- Prior art date
Links
- XPZOKPQZEPSMFC-UHFFFAOYSA-N 4,5-dihydro-1,2-oxazol-3-amine Chemical class NC1=NOCC1 XPZOKPQZEPSMFC-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000935 antidepressant agent Substances 0.000 title 1
- 229940005513 antidepressants Drugs 0.000 title 1
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 4
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 239000000670 adrenergic alpha-2 receptor antagonist Substances 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000005936 piperidyl group Chemical group 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Anesthesiology (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02076239 | 2002-04-02 | ||
| PCT/EP2003/003245 WO2003082878A1 (en) | 2002-04-02 | 2003-03-27 | Substituted amino isoxazoline derivatives and their use as anti-depressants. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20044645L true NO20044645L (no) | 2004-10-27 |
Family
ID=28459528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20044645A NO20044645L (no) | 2002-04-02 | 2004-10-27 | Substituerte amino-isoksazolinderivater og deres anvendelse som antidepressive midler |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US7265103B2 (pl) |
| EP (1) | EP1492796B1 (pl) |
| JP (1) | JP4580653B2 (pl) |
| KR (1) | KR20040093061A (pl) |
| CN (1) | CN100349897C (pl) |
| AR (1) | AR039207A1 (pl) |
| AT (1) | ATE372342T1 (pl) |
| BR (1) | BR0308309A (pl) |
| CA (1) | CA2480113C (pl) |
| DE (1) | DE60316134T2 (pl) |
| DK (1) | DK1492796T3 (pl) |
| EA (1) | EA008189B1 (pl) |
| ES (1) | ES2292949T3 (pl) |
| HK (1) | HK1080072A1 (pl) |
| HR (1) | HRP20040871A2 (pl) |
| IL (2) | IL164341A0 (pl) |
| MX (1) | MXPA04008626A (pl) |
| NO (1) | NO20044645L (pl) |
| NZ (1) | NZ536109A (pl) |
| PL (1) | PL211708B1 (pl) |
| PT (1) | PT1492796E (pl) |
| TW (1) | TWI286138B (pl) |
| WO (1) | WO2003082878A1 (pl) |
| ZA (1) | ZA200407904B (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200409777A (en) | 2002-08-12 | 2004-06-16 | Janssen Pharmaceutica Nv | C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants |
| JP4478570B2 (ja) * | 2002-08-21 | 2010-06-09 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Ｃ６−およびｃ９−置換’４，３−ｃ！イソキサゾリン誘導体およびそれらの抗鬱薬としての使用 |
| ES2331144T3 (es) | 2004-11-26 | 2009-12-22 | Janssen Pharmaceutica Nv | Derivados de isoxazolina-indol con actividad antipsicotica y ansiolitica mejorada. |
| AU2008270444A1 (en) * | 2007-07-03 | 2009-01-08 | F. Hoffmann-La Roche Ag | 4-imidazolines and their use as antidepressants |
| RS53416B (sr) | 2009-03-10 | 2014-12-31 | Takeda Pharmaceutical Company Limited | Derivati benzofurana |
| US20130062732A1 (en) | 2011-09-08 | 2013-03-14 | International Business Machines Corporation | Interconnect structures with functional components and methods for fabrication |
| CN105801510A (zh) * | 2016-04-08 | 2016-07-27 | 李勇 | 一种治疗抑郁症的药物组合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2055011T3 (es) | 1988-09-19 | 1994-08-16 | Akzo Nv | Un procedimiento para la preparacion de derivados de tetrahidronaftaleno e indano. |
| EP0874833A1 (en) * | 1996-01-05 | 1998-11-04 | Hoechst Marion Roussel, Inc. | 4,5-dihydronaphth 1,2-c]isoxazoles and derivatives thereof having cns activity |
| US6187774B1 (en) * | 1996-03-04 | 2001-02-13 | Yoshitomi Pharmaceutical Industries, Ltd. | Fused heterocyclic compounds and pharmaceutical applications thereof |
| CA2437505C (en) * | 2001-02-21 | 2010-02-09 | Janssen Pharmaceutica N.V. | Isoxazoline derivatives as anti-depressants |
| TW200409777A (en) * | 2002-08-12 | 2004-06-16 | Janssen Pharmaceutica Nv | C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants |
| JP4478570B2 (ja) * | 2002-08-21 | 2010-06-09 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Ｃ６−およびｃ９−置換’４，３−ｃ！イソキサゾリン誘導体およびそれらの抗鬱薬としての使用 |
-
2003
- 2003-03-27 AT AT03714897T patent/ATE372342T1/de not_active IP Right Cessation
- 2003-03-27 PT PT03714897T patent/PT1492796E/pt unknown
- 2003-03-27 IL IL16434103A patent/IL164341A0/xx unknown
- 2003-03-27 JP JP2003580343A patent/JP4580653B2/ja not_active Expired - Fee Related
- 2003-03-27 NZ NZ536109A patent/NZ536109A/en unknown
- 2003-03-27 DK DK03714897T patent/DK1492796T3/da active
- 2003-03-27 WO PCT/EP2003/003245 patent/WO2003082878A1/en not_active Ceased
- 2003-03-27 HK HK05112213.1A patent/HK1080072A1/zh unknown
- 2003-03-27 EP EP03714897A patent/EP1492796B1/en not_active Expired - Lifetime
- 2003-03-27 MX MXPA04008626A patent/MXPA04008626A/es active IP Right Grant
- 2003-03-27 EA EA200401297A patent/EA008189B1/ru not_active IP Right Cessation
- 2003-03-27 US US10/510,220 patent/US7265103B2/en not_active Expired - Lifetime
- 2003-03-27 PL PL371630A patent/PL211708B1/pl unknown
- 2003-03-27 CA CA2480113A patent/CA2480113C/en not_active Expired - Fee Related
- 2003-03-27 HR HR20040871A patent/HRP20040871A2/hr not_active Application Discontinuation
- 2003-03-27 BR BR0308309-8A patent/BR0308309A/pt not_active IP Right Cessation
- 2003-03-27 CN CNB038074192A patent/CN100349897C/zh not_active Expired - Fee Related
- 2003-03-27 ES ES03714897T patent/ES2292949T3/es not_active Expired - Lifetime
- 2003-03-27 DE DE60316134T patent/DE60316134T2/de not_active Expired - Lifetime
- 2003-03-27 KR KR10-2004-7012757A patent/KR20040093061A/ko not_active Ceased
- 2003-04-01 TW TW092107328A patent/TWI286138B/zh not_active IP Right Cessation
- 2003-04-01 AR ARP030101126A patent/AR039207A1/es unknown
-
2004
- 2004-09-28 IL IL164341A patent/IL164341A/en not_active IP Right Cessation
- 2004-09-30 ZA ZA200407904A patent/ZA200407904B/xx unknown
- 2004-10-27 NO NO20044645A patent/NO20044645L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN100349897C (zh) | 2007-11-21 |
| HK1080072A1 (zh) | 2006-04-21 |
| ZA200407904B (en) | 2005-10-20 |
| IL164341A0 (en) | 2005-12-18 |
| MXPA04008626A (es) | 2004-12-06 |
| AR039207A1 (es) | 2005-02-09 |
| CN1642960A (zh) | 2005-07-20 |
| NZ536109A (en) | 2006-06-30 |
| TWI286138B (en) | 2007-09-01 |
| CA2480113C (en) | 2012-04-24 |
| HRP20040871A2 (en) | 2005-04-30 |
| IL164341A (en) | 2009-06-15 |
| PT1492796E (pt) | 2007-11-16 |
| DE60316134T2 (de) | 2008-05-29 |
| BR0308309A (pt) | 2004-12-28 |
| CA2480113A1 (en) | 2003-10-09 |
| DE60316134D1 (de) | 2007-10-18 |
| EA200401297A1 (ru) | 2005-02-24 |
| WO2003082878A1 (en) | 2003-10-09 |
| TW200406414A (en) | 2004-05-01 |
| PL211708B1 (pl) | 2012-06-29 |
| EP1492796B1 (en) | 2007-09-05 |
| JP2005522469A (ja) | 2005-07-28 |
| AU2003219111A1 (en) | 2003-10-13 |
| EP1492796A1 (en) | 2005-01-05 |
| EA008189B1 (ru) | 2007-04-27 |
| US7265103B2 (en) | 2007-09-04 |
| ES2292949T3 (es) | 2008-03-16 |
| DK1492796T3 (da) | 2007-12-03 |
| ATE372342T1 (de) | 2007-09-15 |
| US20050222125A1 (en) | 2005-10-06 |
| JP4580653B2 (ja) | 2010-11-17 |
| KR20040093061A (ko) | 2004-11-04 |
| PL371630A1 (pl) | 2005-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |