HRP20060119A2 - A method of removing the triphenylmethane protecting group - Google Patents

A method of removing the triphenylmethane protecting group Download PDF

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Publication number
HRP20060119A2
HRP20060119A2 HR20060119A HRP20060119A HRP20060119A2 HR P20060119 A2 HRP20060119 A2 HR P20060119A2 HR 20060119 A HR20060119 A HR 20060119A HR P20060119 A HRP20060119 A HR P20060119A HR P20060119 A2 HRP20060119 A2 HR P20060119A2
Authority
HR
Croatia
Prior art keywords
formula
image
trityl
biphenyl
methyl
Prior art date
Application number
HR20060119A
Other languages
English (en)
Croatian (hr)
Inventor
Radl Stanislav
Stach Jan
Klecan Ondrej
Original Assignee
Zentiva
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CZ20032319A external-priority patent/CZ297016B6/cs
Priority claimed from CZ20040733A external-priority patent/CZ298329B6/cs
Application filed by Zentiva filed Critical Zentiva
Publication of HRP20060119A2 publication Critical patent/HRP20060119A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Encapsulation Of And Coatings For Semiconductor Or Solid State Devices (AREA)
  • Dicing (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Manufacture Of Electron Tubes, Discharge Lamp Vessels, Lead-In Wires, And The Like (AREA)
  • Peptides Or Proteins (AREA)
HR20060119A 2003-08-27 2004-08-26 A method of removing the triphenylmethane protecting group HRP20060119A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CZ20032319A CZ297016B6 (cs) 2003-08-27 2003-08-27 Zpusob odstranování trifenylmethanové chránicí skupiny z 1-trityl-5-(4'-subst. aminomethyl-1,1' -bifenyl-2-yl)-1H-tetrazolu a zpusob výroby draselné soli losartanu, irbesartanu a valsartanu s jeho pouzitím
CZ20040733A CZ298329B6 (cs) 2004-06-16 2004-06-16 Zpusob výroby 1-(cyklohexyloxykarbonyloxy)ethyl-2-ethoxy-1-[[2´-(1H-tetrazol-5-yl)bifenyl-4-yl]methyl]benzimidazol-7-karboxylátu (candesartan cilexetilu)
PCT/CZ2004/000051 WO2005021535A2 (en) 2003-08-27 2004-08-26 A method of removing the triphenylmethane protecting group

Publications (1)

Publication Number Publication Date
HRP20060119A2 true HRP20060119A2 (en) 2006-05-31

Family

ID=34276338

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20060119A HRP20060119A2 (en) 2003-08-27 2004-08-26 A method of removing the triphenylmethane protecting group

Country Status (13)

Country Link
US (1) US20060287537A1 (de)
EP (1) EP1658281B1 (de)
AT (1) ATE482950T1 (de)
CA (1) CA2536781A1 (de)
DE (1) DE602004029373D1 (de)
EA (1) EA011507B1 (de)
ES (1) ES2348300T3 (de)
HR (1) HRP20060119A2 (de)
PL (2) PL1658281T3 (de)
PT (1) PT1658281E (de)
RS (1) RS20060125A (de)
SK (1) SK50142006A3 (de)
WO (1) WO2005021535A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005077941A2 (en) 2004-02-11 2005-08-25 Teva Pharmaceutical Industries Ltd. Candesartan cilexetil polymorphs
WO2006050922A1 (en) * 2004-11-11 2006-05-18 Lek Pharmaceuticals D.D. Process for the synthesis of tetrazoles
EP1661891A1 (de) * 2004-11-30 2006-05-31 KRKA, D.D., Novo Mesto Verfahren zur Herstellung von Valsartan
SI22127A (sl) 2005-10-07 2007-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Postopek za pripravo kandesartan cileksetila
CZ299902B6 (cs) * 2005-10-27 2008-12-29 Zentiva, A. S Zpusob odstranování trifenylmethanové chránicí skupiny u prekurzoru antihypertenzních léciv
WO2008018843A1 (en) * 2006-08-08 2008-02-14 Ulkar Kimya Sanayi Ve Ticaret As Process for producing useful salts form of biphenyl-tetrazole compounds
US8492577B2 (en) 2008-04-07 2013-07-23 Hetero Research Foundation Process for preparation of valsartan intermediate
WO2010046804A2 (en) * 2008-10-21 2010-04-29 Alembic Limited A process for preparation of losartan potassium form i
CA2762846A1 (en) 2009-05-20 2010-11-25 Ranbaxy Laboratories Limited Process for the preparation of olmesartan medoxomil
WO2011080684A1 (en) 2009-12-31 2011-07-07 Ranbaxy Laboratories Limited Process for the preparation of candesartan cilexetil
WO2011092666A1 (en) 2010-01-29 2011-08-04 Ranbaxy Laboratories Limited An improved process for the preparation of candesartan cilexetil, polymorphic forms of n-trityl candesartan and their uses thereof
CN103012382B (zh) * 2012-12-05 2016-10-05 迪沙药业集团有限公司 一种奥美沙坦酯的制备方法
CA2962922C (en) 2014-09-29 2021-10-26 The Scripps Research Institute Sphingosine-1-phosphate receptor modulators for treatment of cardiopulmonary disorders
US11327065B1 (en) * 2021-08-27 2022-05-10 Jubilant Generics Limited Preparation of angiotensin receptor blockers or pharmaceutically acceptable salts thereof
CN116606282A (zh) * 2023-05-17 2023-08-18 杭州新曦科技有限公司 用于制备氯沙坦钾及其相关中间体的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE122007000050I1 (de) * 1990-02-19 2007-11-08 Novartis Ag Acylverbindungen
US5270317A (en) * 1990-03-20 1993-12-14 Elf Sanofi N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
US5196444A (en) * 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
AT395853B (de) * 1991-01-31 1993-03-25 Chem Pharm Forsch Gmbh Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung
US5281604A (en) * 1993-04-23 1994-01-25 American Cyanamid Company Angiotensin II receptor blocking 2,3,6-substituted quinazolinones
JP2004520446A (ja) * 2001-05-18 2004-07-08 オーロビンド ファーマ リミテッド ロサルタンカリウムの結晶化方法

Also Published As

Publication number Publication date
CA2536781A1 (en) 2005-03-10
US20060287537A1 (en) 2006-12-21
EA011507B1 (ru) 2009-04-28
EA200600079A1 (ru) 2006-08-25
ATE482950T1 (de) 2010-10-15
RS20060125A (sr) 2008-06-05
PL379886A1 (pl) 2006-11-27
EP1658281B1 (de) 2010-09-29
WO2005021535A3 (en) 2005-06-09
DE602004029373D1 (de) 2010-11-11
EP1658281A2 (de) 2006-05-24
ES2348300T3 (es) 2010-12-02
PT1658281E (pt) 2010-10-12
WO2005021535A2 (en) 2005-03-10
PL1658281T3 (pl) 2010-12-31
SK50142006A3 (sk) 2006-05-04

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