HRP20060127A2 - Arylindenopyridines and arylindenopyridines and their use as adenosine a2a receptor antagonist - Google Patents
Arylindenopyridines and arylindenopyridines and their use as adenosine a2a receptor antagonistInfo
- Publication number
- HRP20060127A2 HRP20060127A2 HR20060127A HRP20060127A HRP20060127A2 HR P20060127 A2 HRP20060127 A2 HR P20060127A2 HR 20060127 A HR20060127 A HR 20060127A HR P20060127 A HRP20060127 A HR P20060127A HR P20060127 A2 HRP20060127 A2 HR P20060127A2
- Authority
- HR
- Croatia
- Prior art keywords
- arylindenopyridines
- adenosine
- receptor antagonist
- pharmaceutical compositions
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2003/031471 WO2005042500A1 (en) | 2003-10-03 | 2003-10-03 | Arylindenopyridines and arylindenopyridines and their use as adenosine a2a receptor antagonist |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20060127A2 true HRP20060127A2 (en) | 2006-07-31 |
Family
ID=34548801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20060127A HRP20060127A2 (en) | 2003-10-03 | 2003-10-03 | Arylindenopyridines and arylindenopyridines and their use as adenosine a2a receptor antagonist |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1673354B1 (de) |
| JP (1) | JP4725963B2 (de) |
| CN (1) | CN1878761A (de) |
| AT (1) | ATE429421T1 (de) |
| AU (1) | AU2003275430A1 (de) |
| BR (1) | BR0318521A (de) |
| CA (1) | CA2540686A1 (de) |
| CY (1) | CY1109808T1 (de) |
| DE (1) | DE60327375D1 (de) |
| DK (1) | DK1673354T3 (de) |
| EA (1) | EA200600688A1 (de) |
| EC (1) | ECSP066474A (de) |
| ES (1) | ES2326075T3 (de) |
| HR (1) | HRP20060127A2 (de) |
| IL (1) | IL174678A0 (de) |
| IS (1) | IS8377A (de) |
| NO (1) | NO20061981L (de) |
| PT (1) | PT1673354E (de) |
| RS (1) | RS20060237A (de) |
| SI (1) | SI1673354T1 (de) |
| WO (1) | WO2005042500A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2273599B1 (es) | 2005-10-14 | 2008-06-01 | Universidad De Barcelona | Compuestos para el tratamiento de la fibrilacion auricular. |
| AU2007272956B2 (en) | 2006-07-11 | 2013-05-02 | Janssen Pharmaceutica, N.V. | Benzofuro-and benzothienopyryimidine modulators of the histamine H4 receptor |
| US7985745B2 (en) | 2006-10-02 | 2011-07-26 | Abbott Laboratories | Method for pain treatment |
| US8735411B2 (en) | 2006-10-02 | 2014-05-27 | Abbvie Inc. | Macrocyclic benzofused pyrimidine derivatives |
| US7960400B2 (en) | 2007-08-27 | 2011-06-14 | Duquesne University Of The Holy Ghost | Tricyclic compounds having cytostatic and/or cytotoxic activity and methods of use thereof |
| WO2009055308A1 (en) | 2007-10-24 | 2009-04-30 | Janssen Pharmaceutica, N.V. | Arylindenopyrimidines and their use as adenosine a2a receptor antagonists |
| PA8801401A1 (es) * | 2007-10-25 | 2009-05-15 | Janssen Pharmaceutica Nv | Arilindenopirimidinas y su uso como adenosina a2a |
| US20100093763A1 (en) * | 2008-10-13 | 2010-04-15 | Barbay J Kent | PHENYL SUBSTITUTED THIENO[2,3-d]PYRIMIDINES AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS |
| US20110105492A1 (en) * | 2009-10-29 | 2011-05-05 | Jackson Paul F | ARYL SUBSTITUTED ARYLINDENOPYRIMIDINES AND THEIR USE AS HIGHLY SELECTIVE ADENOSINE A2a RECEPTOR ANTAGONISTS |
| US20110105540A1 (en) * | 2009-10-29 | 2011-05-05 | Jackson Paul F | 2-AMINO-9-[4-(4-METHOXY-PHENOXY)-PIPERIDIN-1-YL]-4-PHENYL-INDENO[1,2-D]PYRIMIDIN-5-ONE AND ITS USE AS A HIGHLY SELECTIVE ADENOSINE A2a RECEPTOR ANTAGONIST |
| US20110105493A1 (en) * | 2009-10-29 | 2011-05-05 | Jackson Paul F | HETEROCYCLYL SUBSTITUTED ARYLINDENOPYRIMIDINES AND THEIR USE AS HIGHLY SELECTIVE ADENOSINE A2a RECEPTOR ANTAGONISTS |
| US20110105494A1 (en) * | 2009-10-29 | 2011-05-05 | Jackson Paul F | Heteroaryl substituted arylindenopyrimidines and their use as highly selective adenosine a2a receptor antagonists |
| US20110105541A1 (en) * | 2009-10-29 | 2011-05-05 | Jackson Paul F | ALKYL SUBSTITUTED ARYLINDENOPYRIMIDINES AND THEIR USE AS HIGHLY SELECTIVE ADENOSINE A2a RECEPTOR ANTAGONISTS |
| WO2016114668A1 (en) | 2015-01-16 | 2016-07-21 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Method to prepare phenolics from biomass |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993008167A1 (fr) * | 1991-10-24 | 1993-04-29 | Nippon Soda Co., Ltd. | Nouveau derive heterocyclique et bactericide agrohorticole le renfermant |
| ES2126773T3 (es) * | 1993-09-15 | 1999-04-01 | Merck Sharp & Dohme | Derivados triciclicos heteroaromaticos condensados como ligandos de subtipos de receptores de dopamina. |
| JP2001139556A (ja) * | 1999-03-18 | 2001-05-22 | Nippon Soda Co Ltd | インデノピリジンおよびインデノピリミジン化合物並びにその製造法 |
| JP4064671B2 (ja) * | 2000-02-25 | 2008-03-19 | エフ．ホフマン−ラ ロシュ アーゲー | アデノシン受容体モジュレーター |
| EP1385843A1 (de) * | 2001-04-18 | 2004-02-04 | Ortho-Mcneil Pharmaceutical, Inc. | Arylindenopyridine mit pde-inhibierender wirkung |
| US6958328B2 (en) * | 2001-04-18 | 2005-10-25 | Ortho-Mcneil Pharmaceutical, Inc | Arylindenopyridines and related therapeutic and prophylactic methods |
-
2003
- 2003-10-03 AT AT03759708T patent/ATE429421T1/de active
- 2003-10-03 WO PCT/US2003/031471 patent/WO2005042500A1/en not_active Ceased
- 2003-10-03 PT PT03759708T patent/PT1673354E/pt unknown
- 2003-10-03 EP EP03759708A patent/EP1673354B1/de not_active Expired - Lifetime
- 2003-10-03 DK DK03759708T patent/DK1673354T3/da active
- 2003-10-03 EA EA200600688A patent/EA200600688A1/ru unknown
- 2003-10-03 AU AU2003275430A patent/AU2003275430A1/en not_active Abandoned
- 2003-10-03 CN CNA2003801107612A patent/CN1878761A/zh active Pending
- 2003-10-03 RS YUP-2006/0237A patent/RS20060237A/sr unknown
- 2003-10-03 ES ES03759708T patent/ES2326075T3/es not_active Expired - Lifetime
- 2003-10-03 SI SI200331625T patent/SI1673354T1/sl unknown
- 2003-10-03 BR BRPI0318521-4A patent/BR0318521A/pt not_active IP Right Cessation
- 2003-10-03 DE DE60327375T patent/DE60327375D1/de not_active Expired - Lifetime
- 2003-10-03 HR HR20060127A patent/HRP20060127A2/xx not_active Application Discontinuation
- 2003-10-03 CA CA002540686A patent/CA2540686A1/en not_active Abandoned
- 2003-10-03 JP JP2005510193A patent/JP4725963B2/ja not_active Expired - Fee Related
-
2006
- 2006-03-27 IS IS8377A patent/IS8377A/is unknown
- 2006-03-30 IL IL174678A patent/IL174678A0/en unknown
- 2006-04-03 EC EC2006006474A patent/ECSP066474A/es unknown
- 2006-05-03 NO NO20061981A patent/NO20061981L/no not_active Application Discontinuation
-
2009
- 2009-07-14 CY CY20091100752T patent/CY1109808T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IS8377A (is) | 2006-03-27 |
| EP1673354B1 (de) | 2009-04-22 |
| CN1878761A (zh) | 2006-12-13 |
| DE60327375D1 (de) | 2009-06-04 |
| BR0318521A (pt) | 2006-09-12 |
| SI1673354T1 (sl) | 2009-10-31 |
| JP2007521243A (ja) | 2007-08-02 |
| ECSP066474A (es) | 2006-10-10 |
| IL174678A0 (en) | 2006-08-20 |
| ATE429421T1 (de) | 2009-05-15 |
| EP1673354A1 (de) | 2006-06-28 |
| EA200600688A1 (ru) | 2006-10-27 |
| JP4725963B2 (ja) | 2011-07-13 |
| CY1109808T1 (el) | 2014-09-10 |
| AU2003275430A1 (en) | 2005-05-19 |
| ES2326075T3 (es) | 2009-09-30 |
| DK1673354T3 (da) | 2009-07-27 |
| NO20061981L (no) | 2006-07-03 |
| PT1673354E (pt) | 2009-07-14 |
| WO2005042500A1 (en) | 2005-05-12 |
| RS20060237A (sr) | 2008-11-28 |
| CA2540686A1 (en) | 2005-05-12 |
| HK1091200A1 (en) | 2007-01-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1109808T1 (el) | Αρυλινδενο-πυριδινες και αρυλινδενο-πυριμιδινες και η χρηση τους ως ανταγωνιστων των υποδοχεων αδενοσινης α2α | |
| MEP45308A (en) | [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia | |
| MXPA05011710A (es) | Derivados de pirimidina con actividad de crf. | |
| EA200500342A1 (ru) | Гетероциклические замещённые пиперазины для лечения шизофрении | |
| ATE466860T1 (de) | Cgrp-rezeptorantagonisten | |
| ATE461178T1 (de) | Pyridazinyl-piperazine und deren verwendung als histamin-h3-rezeptorliganden | |
| TW200505903A (en) | CGRP receptor antagonists | |
| ATE384050T1 (de) | Benzazepinderivate als histamin-h3-antagonisten | |
| ATE464304T1 (de) | Carboxamid-spirolactam-cgrp-rezeptor-antagonist n | |
| PT1716152E (pt) | Compostos heterocíclicos fundidos e sua utilização como antagonistas do receptor metabotrópico para o tratamento de distúrbios gastrointestinais | |
| EA200501595A1 (ru) | Азабициклические производные в качестве антагонистов мускаринового рецептора | |
| MXPA06003363A (es) | Derivados de fenil-piperazina como moduladores de receptores muscarinicos. | |
| SE0403171D0 (sv) | New compounds | |
| TW200624432A (en) | Imidazo [1,2-a] pyridine compounds, compositions, uses and methods related thereto | |
| TW200514781A (en) | Novel compounds | |
| CL2003002565A1 (es) | Compuestos derivados de 3h-quinazolin-4-ona, su proceso de preparacion, composicion farmaceutica que los contiene, y uso en el tratamiento y prevencion de enfermedades mediadas por inhibidores de mao-b, tales como la enfermedad de alzheimer y demenci | |
| TW200833697A (en) | Spiro-piperidine derivatives | |
| ATE383345T1 (de) | Quinoxalin-3-on-verdindungen als orexin-rezeptor antagonisten. | |
| NO20064238L (no) | Imidazolinderivater med CB1 agonistlsk aktivitet | |
| EA200501593A1 (ru) | Азабициклические производные в качестве антагонистов мускаринового рецептора | |
| ATE467636T1 (de) | Pyrazoloä3 , 4-düazepinderivate als histamin-h3- antagonisten | |
| MX2009005504A (es) | Derivados de espiro piperidina como antagonistas del receptor via. | |
| ATE406363T1 (de) | Methylindole und methylpyrrolopyridine als alpha- 1-adrenerge agonisten | |
| MXPA05012572A (es) | Derivado de 5-h-benzo[d]naft[2,1-b]azepina como antagonistas selectivos del receptor d1/d5 para el tratamiento de la obesidad y trastornos del sistema nervioso central. | |
| DE60224509D1 (de) | Imidazolderivate verwendbar als histamin h3 rezeptorliganden |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| ARAI | Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application | ||
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20110929 Year of fee payment: 9 |
|
| OBST | Application withdrawn |