HRP20060401A2 - Piperazine derivatives of alkyl oxindoles - Google Patents

Piperazine derivatives of alkyl oxindoles

Info

Publication number: HRP20060401A2
Authority: HR; Croatia
Prior art keywords: piperazine derivatives; oxindoles; alkyl; alkyl oxindoles; derivatives
Prior art date: 2004-05-11

Application number

HR20060401A

Other languages

English (en)

Croatian (hr)

Inventor

Volk Bal�zs

Bark�czy J�zsef

Simig Gyula

Mezei Tibor

Kapillern� Dezsofi Rita

Gacs�lyi Istv�n

Pallagi Katalin

Gigler G�bor

L�vay Gy�rgy

M�ricz Krisztina

Leveleki Csilla

Sziray N�ra

Sz�n�si G�bor

Egyed Andr�s

G�bor H�rsing L�szl�

Original Assignee

Egis Gy�gyszergy�r Nyrt.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-05-11

Filing date

2005-05-10

Publication date

2007-03-31

2004-05-11 Priority claimed from HU0400954A external-priority patent/HU0400954D0/hu

2005-05-05 Priority claimed from HU0500461A external-priority patent/HUP0500461A3/hu

2005-05-10 Application filed by Egis Gy�gyszergy�r Nyrt. filed Critical Egis Gy�gyszergy�r Nyrt.

2007-03-31 Publication of HRP20060401A2 publication Critical patent/HRP20060401A2/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)

HR20060401A 2004-05-11 2005-05-10 Piperazine derivatives of alkyl oxindoles HRP20060401A2 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
HU0400954A HU0400954D0 (en)	2004-05-11	2004-05-11	Piperazine derivatives of alkyl oxindoles
HU0500461A HUP0500461A3 (en)	2005-05-05	2005-05-05	Pyperazine derivatives of alkyl-oxindoles
PCT/HU2005/000048 WO2005108363A1 (en)	2004-05-11	2005-05-10	Piperazine derivatives of alkyl oxindoles

Publications (1)

Publication Number	Publication Date
HRP20060401A2 true HRP20060401A2 (en)	2007-03-31

Family

ID=89985994

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
HR20060401A HRP20060401A2 (en)	2004-05-11	2005-05-10	Piperazine derivatives of alkyl oxindoles
HR20090054T HRP20090054T3 (hr)	2004-05-11	2005-05-10	Derivati piperazina alkilnih oksindola

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
HR20090054T HRP20090054T3 (hr)	2004-05-11	2005-05-10	Derivati piperazina alkilnih oksindola

Country Status (24)

Country	Link
US (1)	US20070219209A1 (de)
EP (1)	EP1751106B1 (de)
JP (1)	JP2007537226A (de)
KR (1)	KR20070011551A (de)
AT (1)	ATE412634T1 (de)
AU (1)	AU2005240842B2 (de)
BG (1)	BG109768A (de)
CA (1)	CA2564009A1 (de)
CZ (1)	CZ2006778A3 (de)
DE (1)	DE602005010694D1 (de)
DK (1)	DK1751106T3 (de)
EA (1)	EA011280B1 (de)
ES (1)	ES2317241T3 (de)
HR (2)	HRP20060401A2 (de)
IL (1)	IL178759A0 (de)
MX (1)	MXPA06013064A (de)
NO (1)	NO20065697L (de)
NZ (1)	NZ551542A (de)
PL (1)	PL1751106T3 (de)
PT (1)	PT1751106E (de)
RS (1)	RS20060620A (de)
SI (1)	SI1751106T1 (de)
SK (1)	SK51112006A3 (de)
WO (1)	WO2005108363A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE602005015223D1 (de) *	2004-05-11	2009-08-13	Egis Gyogyszergyar Nyrt	3-(((4-phenyl)-piperazin-1-yl)-alkyl)-3-alkyl-1,3-dihydro-2h-indol-2-on-derivate und verwandte verbindungen zur behandlung von erkrankungen des zentralnervensystems
US10316025B2 (en)	2015-06-03	2019-06-11	Sunshine Lake Pharma Co., Ltd.	Substituted piperazine compounds and methods of use and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4452808A (en) *	1982-12-07	1984-06-05	Smithkline Beckman Corporation	4-Aminoalkyl-2(3H)-indolones
MX173362B (es) *	1987-03-02	1994-02-23	Pfizer	Compuestos de piperazinil heterociclicos y procedimiento para su preparacion
FR2635104B1 (fr) *	1988-08-03	1992-04-30	Synthelabo	Derives d'indolone, leur preparation et leur application en therapeutique
GB8830312D0 (en) *	1988-12-28	1989-02-22	Lundbeck & Co As H	Heterocyclic compounds
WO1998008816A1 (en) *	1996-08-26	1998-03-05	Meiji Seika Kaisha, Ltd.	Oxindole derivatives and psychotropic drugs

2005
- 2005-05-10 NZ NZ551542A patent/NZ551542A/en unknown
- 2005-05-10 HR HR20060401A patent/HRP20060401A2/xx not_active Application Discontinuation
- 2005-05-10 EP EP05745442A patent/EP1751106B1/de not_active Expired - Lifetime
- 2005-05-10 AU AU2005240842A patent/AU2005240842B2/en not_active Ceased
- 2005-05-10 PT PT05745442T patent/PT1751106E/pt unknown
- 2005-05-10 US US11/596,466 patent/US20070219209A1/en not_active Abandoned
- 2005-05-10 WO PCT/HU2005/000048 patent/WO2005108363A1/en not_active Ceased
- 2005-05-10 PL PL05745442T patent/PL1751106T3/pl unknown
- 2005-05-10 DK DK05745442T patent/DK1751106T3/da active
- 2005-05-10 CZ CZ20060778A patent/CZ2006778A3/cs unknown
- 2005-05-10 SI SI200530563T patent/SI1751106T1/sl unknown
- 2005-05-10 KR KR1020067025135A patent/KR20070011551A/ko not_active Ceased
- 2005-05-10 HR HR20090054T patent/HRP20090054T3/xx unknown
- 2005-05-10 AT AT05745442T patent/ATE412634T1/de active
- 2005-05-10 SK SK5111-2006A patent/SK51112006A3/sk not_active Application Discontinuation
- 2005-05-10 MX MXPA06013064A patent/MXPA06013064A/es active IP Right Grant
- 2005-05-10 JP JP2007512356A patent/JP2007537226A/ja active Pending
- 2005-05-10 CA CA002564009A patent/CA2564009A1/en not_active Abandoned
- 2005-05-10 DE DE602005010694T patent/DE602005010694D1/de not_active Expired - Lifetime
- 2005-05-10 ES ES05745442T patent/ES2317241T3/es not_active Expired - Lifetime
- 2005-05-10 EA EA200602080A patent/EA011280B1/ru not_active IP Right Cessation
- 2005-05-10 RS RSP-2006/0620A patent/RS20060620A/sr unknown
2006
- 2006-10-19 IL IL178759A patent/IL178759A0/en unknown
- 2006-12-11 NO NO20065697A patent/NO20065697L/no not_active Application Discontinuation
- 2006-12-11 BG BG109768A patent/BG109768A/bg unknown

Also Published As

Publication number	Publication date
SI1751106T1 (sl)	2009-06-30
AU2005240842B2 (en)	2011-10-06
AU2005240842A1 (en)	2005-11-17
ATE412634T1 (de)	2008-11-15
SK51112006A3 (sk)	2007-05-03
EA200602080A1 (ru)	2007-04-27
DE602005010694D1 (de)	2008-12-11
EA011280B1 (ru)	2009-02-27
CA2564009A1 (en)	2005-11-17
EP1751106B1 (de)	2008-10-29
DK1751106T3 (da)	2009-03-09
BG109768A (bg)	2008-03-31
NO20065697L (no)	2007-02-02
JP2007537226A (ja)	2007-12-20
CZ2006778A3 (cs)	2007-03-07
ES2317241T3 (es)	2009-04-16
NZ551542A (en)	2010-06-25
US20070219209A1 (en)	2007-09-20
EP1751106A1 (de)	2007-02-14
PT1751106E (pt)	2009-02-10
KR20070011551A (ko)	2007-01-24
PL1751106T3 (pl)	2009-07-31
WO2005108363A1 (en)	2005-11-17
RS20060620A (sr)	2008-09-29
MXPA06013064A (es)	2007-04-27
HRP20090054T3 (hr)	2009-03-31
IL178759A0 (en)	2007-02-11

Legal Events

Date	Code	Title	Description
2007-03-31	A1OB	Publication of a patent application
2007-08-16	AIPI	Request for the grant of a patent on the basis of a substantive examination of a patent application
2010-04-19	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20100419 Year of fee payment: 6
2011-11-14	OBST	Application withdrawn

Publication	Publication Date	Title
SE0303180D0 (sv)	2003-11-26	Novel compounds
SE0302232D0 (sv)	2003-08-18	Novel Compounds
SE0201635D0 (sv)	2002-05-30	Novel compounds
EA201100749A1 (ru)	2011-10-31	Производные пиридина и пиримидина в качестве ингибиторов фосфодиэстеразы 10
CY1112914T1 (el)	2016-04-13	Υποκατεστημενα παραγωγα ινδολυλ αλκυλ αμινης ως νεοι αναστολεις των αποακετυλασων ιστονης
MA30076B1 (fr)	2008-12-01	Carbonylaminopyrrolopyrazoles servant de puissants inhibiteurs de kinases.
EA201100311A1 (ru)	2011-10-31	Амидные производные гетероарилов и их применение в качестве активаторов глюкокиназы
ATE429427T1 (de)	2009-05-15	Pyrimidinderivate als orexin-rezeptorantagonisten
CY1109854T1 (el)	2014-09-10	Παραγωγα αζαδικυκλο(3.1.0)εξανιου χρησιμα ως ρυθμιστες υποδοχεων d3 ντοπαμινης
SE0202241D0 (sv)	2002-07-17	Novel Compounds
HRP20050533A2 (en)	2006-11-30	Aminoindazole derivatives and use thereof as kinase inhibitors
EA201001481A1 (ru)	2011-06-30	Производные третичного амина в качестве ингибиторов фосфодиэстеразы-4
DE60214990D1 (de)	2006-11-09	Benzolsulfonsäureester-indol-5-yl als 5-ht6 rezeptor-antagonisten
EA201070804A1 (ru)	2010-12-30	(аза)индольное производное, замещенное по положению 5, содержащая его фармацевтическая композиция, промежуточные соединения и способ их получения
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EA201000675A1 (ru)	2011-06-30	Производные хромана как модуляторы trpv3
MX2007011847A (es)	2008-03-11	Derivados de pirimidindiona como antagonistas del receptor de procineticina 2.
MX2007011848A (es)	2008-04-22	Antagonistas del receptor de procineticina i.
TW200728258A (en)	2007-08-01	Novel compounds
DE502008002974D1 (de)	2011-05-05	ä Ä5- ( PHENYL) - 6- PHENYLPYRROLO Ä2,1-FÜÄ2,1, 4ÜTRIAZIN-4-YLÜAMINOü CARBONSÄUREDERIVATE UND VERWANDTE VERBINDUNGEN ALS PROSTAZYKLIN (PGI2) IP-REZEPTOR AKTIVATOREN ZUR BEHANDLUNG VON KARDIOVASKULÄREN ERKRANKUNGEN
EA200801366A1 (ru)	2008-10-30	Производные 3,6-дигидро-2-оксо-6н-1,3,4-тиадиазина
ATE542796T1 (de)	2012-02-15	N-sulfonylcarboximidamidverbindungen als apoptosepromotoren
HRP20060401A2 (en)	2007-03-31	Piperazine derivatives of alkyl oxindoles
HRP20060420A2 (en)	2007-04-30	Piperazine derivatives of alkyl oxindoles
EA200801549A1 (ru)	2008-10-30	Новые производные фенантридина в качестве антагонистов брадикинина