HRP20070328T3 - SUPSTITUIRANI 8'-PIRI(MI)DINILDIHIDROSPIRO[CIKLO-ALKLIAMIN]PIRIMIDO[1,2-a]PIRIMIDIN-6-ONSKI DERIVATI - Google Patents

SUPSTITUIRANI 8'-PIRI(MI)DINILDIHIDROSPIRO[CIKLO-ALKLIAMIN]PIRIMIDO[1,2-a]PIRIMIDIN-6-ONSKI DERIVATI

Info

Publication number: HRP20070328T3
Authority: HR; Croatia
Prior art keywords: group; groups; alkyl; optionally substituted; alkyl group
Prior art date: 2003-12-19

Application number

HR20070328T

Other languages

English (en)

Croatian (hr)

Inventor

Chereze Nathalie

Lochead Alistair

Saady Mourad

Slowinski Franck

Yaiche Philippe

Original Assignee

Sanofi-Aventis

Mitsubishi Pharma Corporation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-12-19

Filing date

2004-12-17

Publication date

2008-03-31

2004-12-17 Application filed by Sanofi-Aventis, Mitsubishi Pharma Corporation filed Critical Sanofi-Aventis

2008-03-31 Publication of HRP20070328T3 publication Critical patent/HRP20070328T3/xx

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/527—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim spiro-condensed
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/141—Feedstock

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Hematology (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)
Psychology (AREA)
Dermatology (AREA)
Obesity (AREA)
Epidemiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Oncology (AREA)
Heart & Thoracic Surgery (AREA)
Emergency Medicine (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

HR20070328T 2003-12-19 2004-12-17 SUPSTITUIRANI 8'-PIRI(MI)DINILDIHIDROSPIRO[CIKLO-ALKLIAMIN]PIRIMIDO[1,2-a]PIRIMIDIN-6-ONSKI DERIVATI HRP20070328T3 (hr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP03293236A EP1557417B1 (en)	2003-12-19	2003-12-19	Substituted 8'-pyri(mi)dinyl-dihydrospiro-[cycloalkylamine]-pyrimido[1,2-a] pyrimidin-6-one derivatives
PCT/EP2004/014846 WO2005058908A1 (en)	2003-12-19	2004-12-17	SUBSTITUTED 8’-PYRI(MI)DINYL-DIHYDROSPIRO-[CYCLOALKYLAMINE]-PYRIMIDO[1,2-a]PYRIMIDIN-6-ONE DERIVATIVES

Publications (1)

Publication Number	Publication Date
HRP20070328T3 true HRP20070328T3 (hr)	2008-03-31

Family

ID=34626443

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20070328T HRP20070328T3 (hr)	2003-12-19	2004-12-17	SUPSTITUIRANI 8'-PIRI(MI)DINILDIHIDROSPIRO[CIKLO-ALKLIAMIN]PIRIMIDO[1,2-a]PIRIMIDIN-6-ONSKI DERIVATI

Country Status (28)

Country	Link
US (2)	US7294631B2 (sr)
EP (2)	EP1557417B1 (sr)
JP (1)	JP4896734B2 (sr)
KR (1)	KR20060127055A (sr)
CN (1)	CN1914208B (sr)
AR (1)	AR047056A1 (sr)
AT (1)	ATE360632T1 (sr)
AU (1)	AU2004299285B2 (sr)
BR (1)	BRPI0417208A (sr)
CA (1)	CA2550168A1 (sr)
CY (1)	CY1107982T1 (sr)
DE (1)	DE602004006169T2 (sr)
DK (1)	DK1699795T3 (sr)
EA (1)	EA010419B1 (sr)
ES (1)	ES2286707T3 (sr)
HR (1)	HRP20070328T3 (sr)
IL (1)	IL176287A0 (sr)
ME (1)	MEP21408A (sr)
MX (1)	MXPA06006931A (sr)
NO (1)	NO20063187L (sr)
NZ (1)	NZ547956A (sr)
PL (1)	PL1699795T3 (sr)
PT (1)	PT1699795E (sr)
RS (1)	RS50519B (sr)
SI (1)	SI1699795T1 (sr)
TW (1)	TWI346664B (sr)
WO (1)	WO2005058908A1 (sr)
ZA (1)	ZA200604960B (sr)

Families Citing this family (37)

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CN101237875B (zh) *	2005-07-29	2011-07-13	巴塞罗纳大学	用于治疗神经退行性障碍特别是阿尔茨海默病或精神分裂症的含钨盐（vi）的药物组合物
JP2010500300A (ja)	2006-08-08	2010-01-07	サノフィ−アベンティス	アリールアミノアリール−アルキル−置換イミダゾリジン−２，４−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用
EP1921080B1 (en) *	2006-11-07	2009-08-05	Sanofi-Aventis	Subsitituted 8-piperidinyl-2-pyridinyl-pyrimido(1,2-a)pyrimidin-6-one and 8-piperidinyl-2-pyrimidinyl-pyrimido(1,2-a)pyrimidin-6-one derivatives
EP2025674A1 (de)	2007-08-15	2009-02-18	sanofi-aventis	Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP2090579A1 (en) *	2008-01-29	2009-08-19	Sanofi-Aventis	Substituted heteroarylamide diazepinopyrimidone derivatives
EP2090578A1 (en)	2008-01-29	2009-08-19	Sanofi-Aventis	Substituted arylamide diazepinopyrimidone derivatives for the treatment of neurodegenerative diseases caused by abnormal activity of GSK3-beta
EP2085400A1 (en)	2008-01-29	2009-08-05	Sanofi-Aventis	Substituted heteroarylamide oxazepinopyrimidone derivatives
EP2085399A1 (en)	2008-01-29	2009-08-05	Sanofi-Aventis	substituted arylamide oxazepinopyrimidone derivatives
WO2010003624A2 (en)	2008-07-09	2010-01-14	Sanofi-Aventis	Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
JPWO2010038397A1 (ja)	2008-10-01	2012-03-01	パナソニック株式会社	情報記録媒体および記録再生装置
WO2010068601A1 (en)	2008-12-08	2010-06-17	Sanofi-Aventis	A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
BRPI1015943A8 (pt)	2009-07-02	2018-01-09	Sanofi Sa	derivados de 1,2,3,4-tetra - hidro - pirimido {1,2-a} pirimidin-6-ona, o respectivo preparo e a respectiva utilização farmacêutica.
RU2012111354A (ru)	2009-08-26	2013-10-10	Санофи	Новые кристаллические гидраты фторгликозидов, содержащие их фармацевтические препараты и их использование
WO2011107494A1 (de)	2010-03-03	2011-09-09	Sanofi	Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2582709B1 (de)	2010-06-18	2018-01-24	Sanofi	Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en)	2010-07-05	2012-06-01	Sanofi Sa	Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en)	2010-07-05	2012-04-16	Sanofi Aventis	Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en)	2010-07-05	2012-04-16	Sanofi Sa	(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
SI2655375T1 (sl)	2010-12-23	2015-03-31	Sanofi	Derivati pirimidinona, njihova priprava in njihova farmacevtska uporaba
EP2683702B1 (de)	2011-03-08	2014-12-24	Sanofi	Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683703B1 (de)	2011-03-08	2015-05-27	Sanofi	Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2012120052A1 (de)	2011-03-08	2012-09-13	Sanofi	Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683705B1 (de)	2011-03-08	2015-04-22	Sanofi	Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120056A1 (de)	2011-03-08	2012-09-13	Sanofi	Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120053A1 (de)	2011-03-08	2012-09-13	Sanofi	Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683699B1 (de)	2011-03-08	2015-06-24	Sanofi	Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120051A1 (de)	2011-03-08	2012-09-13	Sanofi	Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683701B1 (de)	2011-03-08	2014-12-24	Sanofi	Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2013037390A1 (en)	2011-09-12	2013-03-21	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en)	2011-09-27	2015-10-21	Sanofi	6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
FR2992314B1 (fr)	2012-06-22	2015-10-16	Sanofi Sa	Nouveaux derives de 2,3-dihydro-1h-imidazo{1,2-a}pyrimidin-5-one et 1,2,3,4-tetrahydro-pyrimido{1,2-a}pyrimidin-6-one comportant une morpholine substituee, leur preparation et leur utilisation pharmaceutique
FR2992316A1 (fr)	2012-06-22	2013-12-27	Sanofi Sa	Derives de pyrimidinones, leur preparation et leur application en therapeutique
WO2015155738A2 (en)	2014-04-09	2015-10-15	Christopher Rudd	Use of gsk-3 inhibitors or activators which modulate pd-1 or t-bet expression to modulate t cell immunity
EP3592747A1 (en)	2017-03-10	2020-01-15	Council of Scientific and Industrial Research	Spirooxindole compounds as gsk3 inhibitors and process for preparation thereof
CN112739365B (zh)	2018-08-10	2025-10-28	糖平制药公司	三肽以及代谢、心血管和炎性病症的治疗
CN112694478A (zh) *	2020-12-24	2021-04-23	绍兴文理学院	一种硝基取代含哒嗪酮结构的螺吡唑-吡咯里嗪衍生物及其制备方法与应用

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JP2002514196A (ja) *	1996-12-05	2002-05-14	アムジエン・インコーポレーテツド	置換ピリミジノンおよびピリドン化合物ならびに使用方法
KR100800250B1 (ko) *	2000-09-01	2008-02-01	사노피-아벤티스	2-피리디닐-6,7,8,9-테트라히드로피리미도[1,2-α]피리미딘-4-온 및7-피리디닐-2,3-디히드로이미다조[1,2-α]피리미딘-5(1Ｈ)온유도체
CA2457965C (en) *	2001-09-21	2010-06-01	Sanofi-Synthelabo	Substituted 2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1h)one derivatives
EP1295884A1 (en) *	2001-09-21	2003-03-26	Sanofi-Synthelabo	2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a]Pyrimidin-4-one and 7-Pyrimidinyl-2,3-Dihydroimidazo[1,2-a]Pyrimidin-5(1H)one derivatives
EP1340760A1 (en) *	2002-02-28	2003-09-03	Sanofi-Synthelabo	Substituted 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyrimidinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1H)one derivatives
EP1295885A1 (en) *	2001-09-21	2003-03-26	Sanofi-Synthelabo	Substituted 2-pyridinyl-6,7,8,9-tetrahydropyrimido(1,2-a)pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo(1,2-a)pyrimidin-5(1H)one derivatives
JP4570361B2 (ja) *	2001-09-21	2010-10-27	サノフィ−アベンティス	置換した２−ピリミジニル−６，７，８，９−テトラヒドロピリミド［１，２−ａ］ピリミジン−４−オンおよび７−ピリミジニル−２，３−ジヒドロイミダゾ［１，２−ａ］ピリミジン−５（１Ｈ）オン誘導体
EP1340761A1 (en) *	2002-02-28	2003-09-03	Sanofi-Synthelabo	Substituted 2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1H)one derivatives
US7232827B2 (en) *	2002-02-28	2007-06-19	Sanofi-Aventis	Heteroaryl substituted 2-pyridinyl and 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one derivatives
US7192948B2 (en) *	2004-05-28	2007-03-20	Bristol-Myers Squibb Company	Bicyclic heterocycles as HIV integrase inhibitors

2003
- 2003-12-19 EP EP03293236A patent/EP1557417B1/en not_active Expired - Lifetime
2004
- 2004-12-14 TW TW093138812A patent/TWI346664B/zh not_active IP Right Cessation
- 2004-12-17 EA EA200601192A patent/EA010419B1/ru not_active IP Right Cessation
- 2004-12-17 CA CA002550168A patent/CA2550168A1/en not_active Abandoned
- 2004-12-17 HR HR20070328T patent/HRP20070328T3/xx unknown
- 2004-12-17 DE DE602004006169T patent/DE602004006169T2/de not_active Expired - Lifetime
- 2004-12-17 ME MEP-214/08A patent/MEP21408A/xx unknown
- 2004-12-17 RS RSP-2007/0317A patent/RS50519B/sr unknown
- 2004-12-17 EP EP04804431A patent/EP1699795B1/en not_active Expired - Lifetime
- 2004-12-17 AT AT04804431T patent/ATE360632T1/de active
- 2004-12-17 PT PT04804431T patent/PT1699795E/pt unknown
- 2004-12-17 KR KR1020067014364A patent/KR20060127055A/ko not_active Abandoned
- 2004-12-17 NZ NZ547956A patent/NZ547956A/en not_active IP Right Cessation
- 2004-12-17 PL PL04804431T patent/PL1699795T3/pl unknown
- 2004-12-17 BR BRPI0417208-6A patent/BRPI0417208A/pt not_active IP Right Cessation
- 2004-12-17 WO PCT/EP2004/014846 patent/WO2005058908A1/en not_active Ceased
- 2004-12-17 ZA ZA200604960A patent/ZA200604960B/xx unknown
- 2004-12-17 SI SI200430369T patent/SI1699795T1/sl unknown
- 2004-12-17 MX MXPA06006931A patent/MXPA06006931A/es active IP Right Grant
- 2004-12-17 JP JP2006544393A patent/JP4896734B2/ja not_active Expired - Fee Related
- 2004-12-17 DK DK04804431T patent/DK1699795T3/da active
- 2004-12-17 AU AU2004299285A patent/AU2004299285B2/en not_active Ceased
- 2004-12-17 AR ARP040104725A patent/AR047056A1/es unknown
- 2004-12-17 CN CN2004800413403A patent/CN1914208B/zh not_active Expired - Fee Related
- 2004-12-17 ES ES04804431T patent/ES2286707T3/es not_active Expired - Lifetime
2006
- 2006-06-12 US US11/423,557 patent/US7294631B2/en not_active Expired - Fee Related
- 2006-06-13 IL IL176287A patent/IL176287A0/en not_active IP Right Cessation
- 2006-07-10 NO NO20063187A patent/NO20063187L/no not_active Application Discontinuation
2007
- 2007-07-24 CY CY20071100987T patent/CY1107982T1/el unknown
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Also Published As

Publication number	Publication date
AR047056A1 (es)	2006-01-04
US7547705B2 (en)	2009-06-16
DE602004006169T2 (de)	2008-01-10
US20080081820A1 (en)	2008-04-03
AU2004299285B2 (en)	2010-03-18
EA200601192A1 (ru)	2006-10-27
BRPI0417208A (pt)	2007-02-06
CN1914208A (zh)	2007-02-14
DE602004006169D1 (de)	2007-06-06
IL176287A0 (en)	2006-10-05
MXPA06006931A (es)	2007-04-24
NO20063187L (no)	2006-09-19
EP1699795B1 (en)	2007-04-25
ES2286707T3 (es)	2007-12-01
DK1699795T3 (da)	2007-09-10
EA010419B1 (ru)	2008-08-29
RS50519B (sr)	2010-05-07
TWI346664B (en)	2011-08-11
JP2007514707A (ja)	2007-06-07
TW200530247A (en)	2005-09-16
EP1557417B1 (en)	2007-03-07
EP1699795A1 (en)	2006-09-13
JP4896734B2 (ja)	2012-03-14
HK1096401A1 (en)	2007-06-01
EP1557417A1 (en)	2005-07-27
WO2005058908A1 (en)	2005-06-30
ATE360632T1 (de)	2007-05-15
US20070010539A1 (en)	2007-01-11
CY1107982T1 (el)	2013-09-04
MEP21408A (en)	2010-06-10
ZA200604960B (en)	2007-11-28
PT1699795E (pt)	2007-08-03
KR20060127055A (ko)	2006-12-11
US7294631B2 (en)	2007-11-13
AU2004299285A1 (en)	2005-06-30
NZ547956A (en)	2010-03-26
PL1699795T3 (pl)	2008-01-31
CA2550168A1 (en)	2005-06-30
SI1699795T1 (sl)	2007-10-31
CN1914208B (zh)	2010-12-22

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