HRP20070570T3 - Method for producing 1,4-diphenyl azetidinone derivatives - Google Patents

Method for producing 1,4-diphenyl azetidinone derivatives

Info

Publication number
HRP20070570T3
HRP20070570T3 HR20070570T HRP20070570T HRP20070570T3 HR P20070570 T3 HRP20070570 T3 HR P20070570T3 HR 20070570 T HR20070570 T HR 20070570T HR P20070570 T HRP20070570 T HR P20070570T HR P20070570 T3 HRP20070570 T3 HR P20070570T3
Authority
HR
Croatia
Prior art keywords
alkyl
aryl
naryl
coo
substituted
Prior art date
Application number
HR20070570T
Other languages
English (en)
Croatian (hr)
Inventor
Lindenschmidt Andreas
William Will David
Jaehne Gerhard
Andreas Wollmann Theodor
Frick Wendelin
Junker Bernd
Rigal David
Billen Guenter
Jendralla Heiner
Original Assignee
Sanofi-Aventis Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE200410025071 external-priority patent/DE102004025071B4/de
Priority claimed from DE102005010770A external-priority patent/DE102005010770A1/de
Application filed by Sanofi-Aventis Deutschland Gmbh filed Critical Sanofi-Aventis Deutschland Gmbh
Publication of HRP20070570T3 publication Critical patent/HRP20070570T3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HR20070570T 2004-05-21 2005-05-20 Method for producing 1,4-diphenyl azetidinone derivatives HRP20070570T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE200410025071 DE102004025071B4 (de) 2004-05-21 2004-05-21 Verfahren zur Herstellung von Diphenylazetidinon-Derivaten
DE102005010770A DE102005010770A1 (de) 2005-03-09 2005-03-09 Verfahren zur Herstellung von 1,4-Diphenylazetidinon-Derivaten
PCT/EP2005/005498 WO2005113496A1 (de) 2004-05-21 2005-05-20 Verfahren zur herstellung von 1,4-diphenylazetidinon-derivaten

Publications (1)

Publication Number Publication Date
HRP20070570T3 true HRP20070570T3 (en) 2008-01-31

Family

ID=37561403

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20070570T HRP20070570T3 (en) 2004-05-21 2005-05-20 Method for producing 1,4-diphenyl azetidinone derivatives

Country Status (25)

Country Link
US (1) US7488818B2 (da)
EP (1) EP1756049B1 (da)
JP (1) JP2007538042A (da)
KR (1) KR20070027554A (da)
AR (1) AR049184A1 (da)
AT (1) ATE376997T1 (da)
AU (1) AU2005245124A1 (da)
BR (1) BRPI0510150A (da)
CA (1) CA2567149A1 (da)
CY (1) CY1107425T1 (da)
DE (1) DE502005001841D1 (da)
DK (1) DK1756049T3 (da)
ES (1) ES2294712T3 (da)
HR (1) HRP20070570T3 (da)
IL (1) IL178991A0 (da)
MA (1) MA28635B1 (da)
MX (1) MXPA06013456A (da)
NZ (1) NZ551413A (da)
PL (1) PL1756049T3 (da)
PT (1) PT1756049E (da)
RS (1) RS50539B (da)
RU (1) RU2380361C2 (da)
TW (1) TW200611896A (da)
UY (1) UY28912A1 (da)
WO (1) WO2005113496A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0215579D0 (en) 2002-07-05 2002-08-14 Astrazeneca Ab Chemical compounds
CN100471835C (zh) * 2003-12-23 2009-03-25 默克公司 抗高胆固醇血症化合物
EP1699759B1 (en) 2003-12-23 2010-10-20 AstraZeneca AB Diphenylazetidinone derivates possessing cholesterol absorption inhibitory activity
UY29607A1 (es) 2005-06-20 2007-01-31 Astrazeneca Ab Compuestos quimicos
MY148538A (en) 2005-06-22 2013-04-30 Astrazeneca Ab Novel 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions
SA06270191B1 (ar) 2005-06-22 2010-03-29 استرازينيكا ايه بي مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
TW200811098A (en) 2006-04-27 2008-03-01 Astrazeneca Ab Chemical compounds
US20090047716A1 (en) * 2007-06-07 2009-02-19 Nurit Perlman Reduction processes for the preparation of ezetimibe
EP2414529A2 (en) 2009-04-01 2012-02-08 Matrix Laboratories Ltd Enzymatic process for the preparation of (s)-5-(4-fluoro-phenyl)-5-hydroxy- 1morpholin-4-yl-pentan-1-one, an intermediate of ezetimibe and further conversion to ezetimibe
WO2011056895A1 (en) * 2009-11-03 2011-05-12 University Of Notre Dame Du Lac Ionic liquids comprising heteraromatic anions
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
US9670237B2 (en) 2011-09-22 2017-06-06 Ut-Battelle, Llc Phosphonium-based ionic liquids and their use in the capture of polluting gases
WO2015048765A1 (en) 2013-09-30 2015-04-02 University Of Notre Dame Du Lac Compounds, complexes, compositions, methods and systems for heating and cooling
US10086331B2 (en) 2013-11-05 2018-10-02 University Of Notre Dame Du Lac Carbon dioxide capture using phase change ionic liquids
JP6803138B2 (ja) * 2014-10-22 2020-12-23 三星エスディアイ株式会社Samsung SDI Co., Ltd. ホスホニウム系化合物、それを含むエポキシ樹脂組成物、およびそれを用いて製造された半導体装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2107548T3 (es) * 1991-07-23 1997-12-01 Schering Corp Compuestos de beta-lactama sustituidos utiles como agentes hipocolesterolemicos y procedimientos para su preparacion.
FI960095L (fi) * 1993-07-09 1996-01-09 Schering Corp Menetelmä atsetidinonien syntetitoimiseksi
US5631365A (en) * 1993-09-21 1997-05-20 Schering Corporation Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
HRP20030498A2 (en) * 2000-12-21 2005-04-30 Aventis Pharma Deutschland Gmbh Novel 1,2-diphenzylazetidinones, method for producing the same, medicaments containing said compounds, and the use thereof for treating disorders of the lipid metabolism
TWI291957B (en) * 2001-02-23 2008-01-01 Kotobuki Pharmaceutical Co Ltd Beta-lactam compounds, process for repoducing the same and serum cholesterol-lowering agents containing the same

Also Published As

Publication number Publication date
DE502005001841D1 (de) 2007-12-13
EP1756049A1 (de) 2007-02-28
KR20070027554A (ko) 2007-03-09
AR049184A1 (es) 2006-07-05
BRPI0510150A (pt) 2007-10-02
US20070149776A1 (en) 2007-06-28
TW200611896A (en) 2006-04-16
IL178991A0 (en) 2007-03-08
NZ551413A (en) 2009-07-31
MA28635B1 (fr) 2007-06-01
PT1756049E (pt) 2007-12-17
MXPA06013456A (es) 2007-03-01
WO2005113496A1 (de) 2005-12-01
US7488818B2 (en) 2009-02-10
JP2007538042A (ja) 2007-12-27
PL1756049T3 (pl) 2008-02-29
RU2380361C2 (ru) 2010-01-27
CA2567149A1 (en) 2005-12-01
CY1107425T1 (el) 2013-03-13
RS50539B (sr) 2010-05-07
AU2005245124A1 (en) 2005-12-01
RU2006145444A (ru) 2008-06-27
ES2294712T3 (es) 2008-04-01
EP1756049B1 (de) 2007-10-31
DK1756049T3 (da) 2008-02-25
ATE376997T1 (de) 2007-11-15
UY28912A1 (es) 2005-12-30
HK1103296A1 (zh) 2007-12-14

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