HRP20100521T1 - Monoklonska antitijela protiv čimbenika rasta hepatocita - Google Patents

Monoklonska antitijela protiv čimbenika rasta hepatocita Download PDF

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Publication number
HRP20100521T1
HRP20100521T1 HR20100521T HRP20100521T HRP20100521T1 HR P20100521 T1 HRP20100521 T1 HR P20100521T1 HR 20100521 T HR20100521 T HR 20100521T HR P20100521 T HRP20100521 T HR P20100521T HR P20100521 T1 HRP20100521 T1 HR P20100521T1
Authority
HR
Croatia
Prior art keywords
hgf
monoclonal antibody
mab
inhibits
binding
Prior art date
Application number
HR20100521T
Other languages
English (en)
Croatian (hr)
Inventor
Jin Kim Kyung
Su Yi-Chi
Original Assignee
Galaxy Biotech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35320045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20100521(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Galaxy Biotech filed Critical Galaxy Biotech
Publication of HRP20100521T1 publication Critical patent/HRP20100521T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HR20100521T 2004-04-15 2004-08-13 Monoklonska antitijela protiv čimbenika rasta hepatocita HRP20100521T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/825,060 US20040208876A1 (en) 2003-04-18 2004-04-15 Monoclonal antibodies to hepatocyte growth factor
PCT/US2004/026565 WO2005107800A1 (fr) 2004-04-15 2004-08-13 Anticorps monoclonaux du facteur de croissance des hepatocytes

Publications (1)

Publication Number Publication Date
HRP20100521T1 true HRP20100521T1 (hr) 2010-10-31

Family

ID=35320045

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20100521T HRP20100521T1 (hr) 2004-04-15 2004-08-13 Monoklonska antitijela protiv čimbenika rasta hepatocita

Country Status (25)

Country Link
US (5) US20040208876A1 (fr)
EP (2) EP1734995B1 (fr)
JP (2) JP4594381B2 (fr)
KR (1) KR101072736B1 (fr)
CN (1) CN1964738A (fr)
AT (1) ATE473760T1 (fr)
AU (1) AU2004319276C1 (fr)
BR (1) BRPI0418745A (fr)
CA (1) CA2563080C (fr)
CR (1) CR8698A (fr)
CY (1) CY1110783T1 (fr)
DE (1) DE602004028168D1 (fr)
DK (1) DK1734995T3 (fr)
ES (1) ES2346886T3 (fr)
HR (1) HRP20100521T1 (fr)
IL (1) IL178474A (fr)
MX (1) MXPA06011822A (fr)
NO (1) NO20065227L (fr)
NZ (1) NZ550324A (fr)
PL (1) PL1734995T3 (fr)
PT (1) PT1734995E (fr)
RU (1) RU2361879C2 (fr)
SI (1) SI1734995T1 (fr)
WO (1) WO2005107800A1 (fr)
ZA (1) ZA200609407B (fr)

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ME01803B (fr) * 2004-08-05 2010-12-31 Genentech Inc Antagonistes anti-cmet humanises
RU2007146986A (ru) * 2005-06-02 2009-06-27 ГЭЛЭКСИ БАЙОТЕК, ЭлЭлСи (US) Способы лечения опухолей головного мозга с использованием антител
US8470316B2 (en) 2005-10-14 2013-06-25 Chugai Seiyaku Kabushiki Kaisha Agents for suppressing damage to transplanted islets after islet transplantation
RU2450830C2 (ru) 2005-10-21 2012-05-20 Чугаи Сейяку Кабусики Кайся Средства для лечения кардиопатии
AR057582A1 (es) 2005-11-15 2007-12-05 Nat Hospital Organization Agentes para suprimir la induccion de linfocitos t citotoxicos
WO2007061029A1 (fr) * 2005-11-25 2007-05-31 Keio University Agent thérapeutique pour le cancer de la prostate
JP5033643B2 (ja) 2006-01-27 2012-09-26 学校法人慶應義塾 脈絡膜血管新生を伴う疾患の治療剤
AR059922A1 (es) * 2006-04-01 2008-05-07 Galaxy Biotech Llc Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos
JP5754875B2 (ja) 2006-04-07 2015-07-29 国立大学法人大阪大学 筋再生促進剤
US7649083B2 (en) 2006-06-02 2010-01-19 Aveo Pharmaceuticals, Inc. Hepatocyte growth factor (HGF) binding antibody
MX2008015138A (es) 2006-06-02 2009-01-28 Aveo Pharmaceuticals Inc Proteinas de union al factor de crecimiento de hepatocitos (fch).
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AU2008269086B2 (en) * 2007-06-25 2014-06-12 Amgen Inc. Compositions of specific binding agents to hepatocyte growth factor
PE20091827A1 (es) * 2008-04-11 2009-11-20 Galaxy Biotech Llc Combinacion del inhibidor hgf y el inhibidor egf para el tratamiento del cancer
WO2009140549A1 (fr) * 2008-05-14 2009-11-19 Amgen Inc. Combinaisons d'inhibiteurs de vegf(r) et d'inhibiteurs du facteur de croissance d'hépatocyte (c-met) pour le traitement du cancer
TW201503898A (zh) 2008-06-05 2015-02-01 Chugai Pharmaceutical Co Ltd 神經浸潤抑制劑
PA8849001A1 (es) * 2008-11-21 2010-06-28 Lilly Co Eli Anticuerpos de c-met
US8545839B2 (en) * 2008-12-02 2013-10-01 Pierre Fabre Medicament Anti-c-Met antibody
WO2010119991A2 (fr) 2009-04-17 2010-10-21 Takeda Pharmaceutical Company Limited Nouveau procédé de traitement anticancéreux
CN101555912B (zh) * 2009-04-29 2012-10-03 深圳市特辰科技股份有限公司 一种转轮式自锁安全制动装置及其工作方法
EP2287197A1 (fr) * 2009-08-21 2011-02-23 Pierre Fabre Medicament Anticorps anti-cMET et son utilisation pour la détection et le diagnostic du cancer
RS63800B1 (sr) 2010-05-28 2022-12-30 Chugai Pharmaceutical Co Ltd Poboljšanje antitumorskog odgovora t ćelije
EP2588107A1 (fr) 2010-07-01 2013-05-08 Takeda Pharmaceutical Company Limited Combinaison d'un inhibiteur de cmet et d'un anticorps dirigé contre hgf et/ou cmet
WO2012044577A1 (fr) 2010-09-27 2012-04-05 Exelixis, Inc. Doubles inhibiteurs de met et vegf pour le traitement du cancer de la prostate résistant à la castration et des métastases osseuses ostéoblastiques
RU2013155695A (ru) 2011-06-30 2015-08-10 Дженентек, Инк. Препараты антител против с-мет
CZ303636B6 (cs) * 2011-08-19 2013-01-23 Invos, Spol. S R. O. Biokontejner pro sber bioodpadu a komunálního odpadu
CA2847245A1 (fr) 2011-09-09 2013-03-14 Amgen Inc. Utilisation de la proteine c-met pour predire l'efficacite d'anticorps anti-facteur de croissance des hepatocytes (« hgf ») chez des patients atteints d'un cancer de l'ƒsophage et de l'estomac
EP2758430A4 (fr) 2011-09-20 2015-06-03 Lilly Co Eli Anticorps anti-c-met
US20150157619A1 (en) 2012-07-10 2015-06-11 Takeda Pharmaceutical Company Limited Pharmaceutical preparation for injection
EP2708556B1 (fr) 2012-09-12 2018-11-07 Samsung Electronics Co., Ltd Composition pharmaceutique à utiliser dans une thérapie combinée pour la prévention ou le traitement des maladies induites par c-met ou le facteur d'angiogénèse
TW201444868A (zh) * 2013-03-14 2014-12-01 Alder Biopharmaceuticals Inc Ｈｇｆ抗體及其組成物
US9481725B2 (en) 2013-03-14 2016-11-01 Alderbio Holdings, Llc Antibodies to HGF and compositions containing
WO2015031578A1 (fr) * 2013-08-28 2015-03-05 Abbvie Inc. Dosage de hgf
EP3620531A4 (fr) 2017-05-02 2021-03-17 National Center of Neurology and Psychiatry Procédé de prédiction et d'évaluation d'un effet thérapeutique dans des maladies associées à il-6 et à des neutrophiles
WO2019078344A1 (fr) 2017-10-20 2019-04-25 学校法人兵庫医科大学 Composition médicinale contenant un anticorps du recepteur anti-il -6 pour prévenir l'adhérence post-chirurgicale
TWI822728B (zh) 2018-01-31 2023-11-21 加藤元一 含有il-6抑制劑的哮喘治療劑
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WO2024229542A2 (fr) * 2023-05-05 2024-11-14 Instituto Butantan Anticorps monoclonal (mab) humain anti-fgf2, composition pharmaceutique le comprenant, utilisation de celui-ci et kit pour la détection d'un cancer dans un échantillon biologique comprenant ledit mab

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AR059922A1 (es) * 2006-04-01 2008-05-07 Galaxy Biotech Llc Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos

Also Published As

Publication number Publication date
EP1734995B1 (fr) 2010-07-14
US20090104192A1 (en) 2009-04-23
CR8698A (es) 2007-12-17
AU2004319276A1 (en) 2005-11-17
US7494650B2 (en) 2009-02-24
KR101072736B1 (ko) 2011-10-11
HK1094167A1 (en) 2007-03-23
ZA200609407B (en) 2008-07-30
PT1734995E (pt) 2010-08-18
EP1734995A1 (fr) 2006-12-27
IL178474A (en) 2011-04-28
SI1734995T1 (sl) 2010-09-30
AU2004319276C1 (en) 2011-03-03
CN1964738A (zh) 2007-05-16
JP4594381B2 (ja) 2010-12-08
US20080019966A1 (en) 2008-01-24
JP2011012067A (ja) 2011-01-20
DE602004028168D1 (de) 2010-08-26
EP2204191A1 (fr) 2010-07-07
US20120064066A1 (en) 2012-03-15
RU2361879C2 (ru) 2009-07-20
KR20070012711A (ko) 2007-01-26
BRPI0418745A (pt) 2007-12-11
EP1734995A4 (fr) 2007-04-25
ATE473760T1 (de) 2010-07-15
PL1734995T3 (pl) 2010-12-31
MXPA06011822A (es) 2007-03-23
ES2346886T3 (es) 2010-10-21
NO20065227L (no) 2007-01-10
RU2006140257A (ru) 2008-05-20
DK1734995T3 (da) 2010-10-25
CA2563080A1 (fr) 2005-11-17
CA2563080C (fr) 2015-01-27
IL178474A0 (en) 2007-02-11
US20070160613A1 (en) 2007-07-12
US7687063B2 (en) 2010-03-30
JP2007532643A (ja) 2007-11-15
NZ550324A (en) 2009-12-24
CY1110783T1 (el) 2015-06-10
US20040208876A1 (en) 2004-10-21
AU2004319276B2 (en) 2010-08-26
WO2005107800A1 (fr) 2005-11-17

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