HRP930613A2 - 4-oxo-azetidine-2-sulphonic acids amides and their salts, process for their production and their use - Google Patents

4-oxo-azetidine-2-sulphonic acids amides and their salts, process for their production and their use

Info

Publication number: HRP930613A2
Authority: HR; Croatia
Prior art keywords: me2c; hydrogen; azetidine; oxo; salts
Prior art date: 1992-09-08

Application number

HRP4230053.3A

Other languages

English (en)

Inventor

Zinka Brkic

Original Assignee

Pliva Pharm & Chem Works

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-09-08

Filing date

1993-03-30

Publication date

1998-06-30

1993-03-30 Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works

1998-06-30 Publication of HRP930613A2 publication Critical patent/HRP930613A2/xx

Links

-1 4-oxo-azetidine-2-sulphonic acids amides Chemical class 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 2
150000003839 salts Chemical class 0.000 title abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 5
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 abstract 2
238000002360 preparation method Methods 0.000 abstract 2
MBVWZZYHNWLOIK-UHFFFAOYSA-N 4-oxoazetidine-2-sulfonamide Chemical class NS(=O)(=O)C1CC(=O)N1 MBVWZZYHNWLOIK-UHFFFAOYSA-N 0.000 abstract 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
229910003204 NH2 Inorganic materials 0.000 abstract 1
WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical compound C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
238000011203 antimicrobial therapy Methods 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
CTAPFRYPJLPFDF-UHFFFAOYSA-N isoxazole Chemical compound C=1C=NOC=1 CTAPFRYPJLPFDF-UHFFFAOYSA-N 0.000 abstract 1
125000005544 phthalimido group Chemical group 0.000 abstract 1
229910052708 sodium Chemical group 0.000 abstract 1
239000011734 sodium Chemical group 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
150000003952 β-lactams Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)
Cephalosporin Compounds (AREA)

HRP4230053.3A 1992-09-08 1993-03-30 4-oxo-azetidine-2-sulphonic acids amides and their salts, process for their production and their use HRP930613A2 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4230053A DE4230053A1 (de)	1992-09-08	1992-09-08	4-Oxo-azetidin-2-sulfonsäureamide und ihre Salze, Verfahren zu deren Herstellung und ihre Verwendung

Publications (1)

Publication Number	Publication Date
HRP930613A2 true HRP930613A2 (en)	1998-06-30

Family

ID=6467533

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HRP4230053.3A HRP930613A2 (en)	1992-09-08	1993-03-30	4-oxo-azetidine-2-sulphonic acids amides and their salts, process for their production and their use

Country Status (19)

Country	Link
US (1)	US5466686A (cs)
EP (1)	EP0659177B1 (cs)
JP (1)	JPH08501093A (cs)
CN (1)	CN1042130C (cs)
AT (1)	ATE187441T1 (cs)
BG (1)	BG62135B1 (cs)
CA (1)	CA2142275A1 (cs)
CZ (1)	CZ54595A3 (cs)
DE (2)	DE4230053A1 (cs)
ES (1)	ES2142350T3 (cs)
GR (1)	GR3032702T3 (cs)
HR (1)	HRP930613A2 (cs)
HU (1)	HU217979B (cs)
PL (1)	PL173895B1 (cs)
PT (1)	PT659177E (cs)
RO (1)	RO115256B1 (cs)
RU (1)	RU2124003C1 (cs)
SK (1)	SK29295A3 (cs)
WO (1)	WO1994005632A1 (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HRP921292A2 (en) *	1992-11-17	1994-08-31	Pliva Pharm & Chem Works	5-thia-1,4-diazabicyclo (4.2.0.)octane -3,8-dioxo analogs of beta-lactams, the process for the preparation and use thereof
HRP970146A2 (en) *	1997-03-13	1998-10-31	Mice Kovacevic	Epoxi-azetidines, preparation and use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GR59922B (en) *	1974-12-24	1978-03-20	Lilly Co Eli	Process for preparing 3-methylene cepham
JPS58210060A (ja) *	1982-05-31	1983-12-07	Takeda Chem Ind Ltd	２−オキソアゼチジン誘導体、その製造法および用途
US4436596A (en) *	1982-11-16	1984-03-13	Eli Lilly And Company	N-Substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process
US5250525A (en) *	1991-02-12	1993-10-05	Pliva Handels Gmbh	4-oxo-azetidine-2-sulfonic acids and their salts, processes for the preparation thereof and their use

1992
- 1992-09-08 DE DE4230053A patent/DE4230053A1/de not_active Withdrawn
1993
- 1993-03-30 HR HRP4230053.3A patent/HRP930613A2/xx not_active Application Discontinuation
- 1993-09-03 US US08/115,538 patent/US5466686A/en not_active Expired - Fee Related
- 1993-09-08 SK SK292-95A patent/SK29295A3/sk unknown
- 1993-09-08 WO PCT/EP1993/002428 patent/WO1994005632A1/de not_active Ceased
- 1993-09-08 HU HU9500694A patent/HU217979B/hu not_active IP Right Cessation
- 1993-09-08 PT PT93919299T patent/PT659177E/pt unknown
- 1993-09-08 CZ CZ95545A patent/CZ54595A3/cs unknown
- 1993-09-08 JP JP6506898A patent/JPH08501093A/ja active Pending
- 1993-09-08 RO RO95-00477A patent/RO115256B1/ro unknown
- 1993-09-08 ES ES93919299T patent/ES2142350T3/es not_active Expired - Lifetime
- 1993-09-08 RU RU95111375A patent/RU2124003C1/ru active
- 1993-09-08 EP EP93919299A patent/EP0659177B1/de not_active Expired - Lifetime
- 1993-09-08 PL PL93307851A patent/PL173895B1/pl unknown
- 1993-09-08 CA CA002142275A patent/CA2142275A1/en not_active Abandoned
- 1993-09-08 DE DE59309898T patent/DE59309898D1/de not_active Expired - Fee Related
- 1993-09-08 CN CN93117362A patent/CN1042130C/zh not_active Expired - Fee Related
- 1993-09-08 AT AT93919299T patent/ATE187441T1/de not_active IP Right Cessation
1994
- 1994-12-28 BG BG99296A patent/BG62135B1/bg unknown
2000
- 2000-02-18 GR GR20000400400T patent/GR3032702T3/el unknown

Also Published As

Publication number	Publication date
HUT73528A (en)	1996-08-28
CA2142275A1 (en)	1994-03-17
WO1994005632A1 (de)	1994-03-17
US5466686A (en)	1995-11-14
JPH08501093A (ja)	1996-02-06
ATE187441T1 (de)	1999-12-15
PL307851A1 (en)	1995-06-26
RU95111375A (ru)	1997-03-20
CN1099750A (zh)	1995-03-08
CZ54595A3 (en)	1995-12-13
PL173895B1 (pl)	1998-05-29
BG62135B1 (bg)	1999-03-31
GR3032702T3 (en)	2000-06-30
HU9500694D0 (en)	1995-04-28
EP0659177A1 (de)	1995-06-28
HU217979B (hu)	2000-05-28
DE4230053A1 (de)	1994-03-10
PT659177E (pt)	2000-04-28
RU2124003C1 (ru)	1998-12-27
EP0659177B1 (de)	1999-12-08
RO115256B1 (ro)	1999-12-30
BG99296A (bg)	1995-12-29
ES2142350T3 (es)	2000-04-16
DE59309898D1 (de)	2000-01-13
CN1042130C (zh)	1999-02-17
SK29295A3 (en)	1995-09-13

Legal Events

Date	Code	Title
1998-06-30	A1OB	Publication of a patent application
1998-07-16	AIPI	Request for the grant of a patent on the basis of a substantive examination of a patent application
2000-08-30	OBST	Application withdrawn

Publication	Publication Date	Title
GR3029775T3 (en)	1999-06-30	Mono-N-substituted 1,4,7,10-Tetraazacyclododecan-derivatives, process for their preparation and pharmaceutical agent containing them
HUT44001A (en)	1988-01-28	Process for producing new phenoxy-acetamide derivatives and pharmaceutical compositions containing them as active components
HUT58322A (en)	1992-02-28	Process for producing new n-(3-hydroxy-4-piperidinyl)-dihydro-benzofurane-, -dihydro-2h-penzopyrane- and -dihydro-benzodioxine-carboxamide derivatives and pharmaceutical compositions containing them
FI943948A0 (fi)	1994-08-26	Heterosykliset hiilihappojohdannaiset
HUT48589A (en)	1989-06-28	Process for production of new derivatives of substituated n-/1-hydroxi-4-piperidinil/-benzamid
FR2800735B1 (fr)	2002-02-01	Nouvelles aralkyle-1,2-diamines possedant une activite calcimimetique et leur mode de preparation
DE3873578D1 (de)	1992-09-17	Verwendung von tetrahydrobenz(c,d)indol-6-carboxamiden zur herstellung von arzneimitteln zur behandlung von angstzustaenden.
HUP0104033A2 (hu)	2002-05-29	Benzoilpiridazin-származékok, a vegyületeket tartalmazó gyógyszerkészítmények, eljárás az előállításukra és alkalmazásuk
ATE169635T1 (de)	1998-08-15	Therapeutische verbindungen für die behandlung von krankheiten, die mit einem glutathion-defizit assoziiert sind, herstellungsprozess und diese enthaltene pharmazeutische zusammensetzungen
GR3032702T3 (en)	2000-06-30	4-oxo-azetidine-2-sulphonic acid amides and their salts, process for their production and their use.
ES2094545T3 (es)	1997-01-16	Derivados n-substituidos del 3-azabiciclo(3.2.0)heptano, como neurolepticos etc..
ATE90673T1 (de)	1993-07-15	Antifolat-mittel.
DE3674546D1 (de)	1990-10-31	Amidderivate.
IL99777A0 (en)	1992-08-18	Indole derivatives,processes for their preparation and pharmaceutical compositions containing them
HUT68806A (en)	1995-07-28	Isoxazole carboxylic acid amides, process for producing them and their use
JPS56118050A (en)	1981-09-16	Novel n-acylamino acid derivative
ES478502A1 (es)	1980-07-01	Un procedimiento para la preparacion de nuevas n-(piridotie-nopirazol)amidas
SU1781999A1 (ru)	1996-01-10	Ртутная соль адамантан-1-карбоновой кислоты, проявляющая антисептическую активность